50 Matching Annotations
  1. Nov 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sphingosine-1-phosphate receptor 1 reporter mice reveal receptor activation sites in vivo
    1
    1. scibot 22 Nov 2024
      003556

      DOI: 10.1172/JCI71194

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC4001537/
  3. Oct 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Selective translation of nuclear mitochondrial respiratory proteins reprograms succinate metabolism in AML development and chemoresistance
    1
    1. scibot 02 Oct 2024
      Cat#003556

      DOI: 10.1016/j.stem.2024.09.008

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @vtello

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    sciencedirect.com/science/article/pii/S1934590924003229
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
    1
    1. scibot 02 Oct 2024
      JAX:003556

      DOI: 10.1158/0008-5472.CAN-23-3553

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      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
  6. Sep 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification
    1
    1. scibot 04 Sep 2024
      JAX:003556

      DOI: 10.1016/j.devcel.2024.08.007

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

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    sciencedirect.com/science/article/pii/S1534580724004908
  8. Aug 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
    1
    1. scibot 27 Aug 2024
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2024.07.009

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

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    sciencedirect.com/science/article/pii/S1934590924002856
  10. www.sciencedirect.com www.sciencedirect.com
    Baf155 controls hematopoietic differentiation and regeneration through chromatin priming
    1
    1. scibot 01 Aug 2024
      JAX:003556

      DOI: 10.1016/j.celrep.2024.114558

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    sciencedirect.com/science/article/pii/S2211124724008878
  11. Jul 2024
  12. www.sciencedirect.com www.sciencedirect.com
    Innate immune memory after brain injury drives inflammatory cardiac dysfunction
    1
    1. scibot 25 Jul 2024
      Strain #: 003556

      DOI: 10.1016/j.cell.2024.06.028

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @vtello

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    sciencedirect.com/science/article/pii/S0092867424007025
  13. May 2024
  14. www.sciencedirect.com www.sciencedirect.com
    SMARCA5 reprograms AKR1B1-mediated fructose metabolism to control leukemogenesis
    1
    1. scibot 23 May 2024
      003556

      DOI: 10.1016/j.devcel.2024.04.023

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      Curator: @abever99

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    sciencedirect.com/science/article/pii/S153458072400296X
  15. Apr 2024
  16. www.sciencedirect.com www.sciencedirect.com
    GPATCH8 modulates mutant SF3B1 mis-splicing and pathogenicity in hematologic malignancies
    1
    1. scibot 30 Apr 2024
      The Jackson LaboratoryStrain #:003556

      DOI: 10.1016/j.molcel.2024.04.006

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @abever99

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    sciencedirect.com/science/article/pii/S1097276524002843
  17. www.biorxiv.org www.biorxiv.org
    Ascorbate depletion increases quiescence and self-renewal potential in hematopoietic stem cells and multipotent progenitors
    1
    1. scibot 12 Apr 2024
      RRID:IMSR_JAX:003556

      DOI: 10.1101/2024.04.01.587574

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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    biorxiv.org/content/10.1101/2024.04.01.587574v1
  18. Mar 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Type-I-interferon-responsive microglia shape cortical development and behavior
    2
    1. scibot 15 Mar 2024
      JAX:003556

      DOI: 10.1016/j.cell.2024.02.020

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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      RRID:IMSR_JAX:003556
    2. scibot 15 Mar 2024
      JAX:003556

      DOI: 10.1016/j.cell.2024.02.020

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      Curator: @scibot

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    sciencedirect.com/science/article/pii/S0092867424001867
  20. Oct 2023
  21. 52.53.155.43 52.53.155.43
    Cell of origin epigenetic priming determines susceptibility to Tet2 mutation
    1
    1. scibot 20 Oct 2023
      RRID:IMSR_JAX:003556

      DOI: 10.1101/2023.09.04.556230

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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    52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
  22. Mar 2023
  23. europepmc.org europepmc.org
    Hematopoietic stem cells preferentially traffic misfolded proteins to aggresomes and depend on aggrephagy to maintain protein homeostasis
    1
    1. scibot 28 Mar 2023
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2023.02.010

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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    europepmc.org/article/med/36948186
  24. Jan 2023
  25. www.sciencedirect.com www.sciencedirect.com
    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
    1
    1. scibot 06 Jan 2023
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2022.12.006

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1934590922004908
  26. Dec 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis
    1
    1. scibot 16 Dec 2022
      RRID:IMSR_JAX:003556

      DOI: 10.1158/2159-8290.CD-22-0086

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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    ncbi.nlm.nih.gov/pmc/articles/PMC9716249/
  28. Nov 2022
  29. www.sciencedirect.com www.sciencedirect.com
    Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
    2
    1. scibot 24 Nov 2022
      JAX:003556

      DOI: 10.1016/j.celrep.2022.111677

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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      RRID:IMSR_JAX:003556
    2. scibot 24 Nov 2022
      JAX:003

      DOI: 10.1016/j.celrep.2022.111677

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @a5munoz

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      RRIDCUR:Unresolved RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S2211124722015510
  30. Oct 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Bone marrow and periosteal skeletal stem/progenitor cells make distinct contributions to bone maintenance and repair
    1
    1. scibot 22 Oct 2022
      RRID:IMSR_JAX:003

      DOI: 10.1016/j.stem.2022.10.002

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @a5munoz

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      RRID:IMSR_JAX:003556 RRIDCUR:Unresolved
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    sciencedirect.com/science/article/pii/S1934590922004209
  32. Apr 2022
  33. www.sciencedirect.com www.sciencedirect.com
    Concerted type I interferon signaling in microglia and neural cells promotes memory impairment associated with amyloid β plaques
    1
    1. scibot 20 Apr 2022
      The Jackson LaboratoriesStrain #003556

      DOI: 10.1016/j.immuni.2022.03.018

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @sophiastull

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1074761322001418
  34. Mar 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A type I interferon response defines a conserved microglial state required for effective neuronal phagocytosis
    1
    1. scibot 09 Mar 2022
      JAX #003556

      DOI: 10.1101/2021.04.29.441889

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @evieth

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      RRID:IMSR_JAX:003556
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    ncbi.nlm.nih.gov/pmc/articles/PMC8887080/
  36. Nov 2021
  37. www.sciencedirect.com www.sciencedirect.com
    HRD1-mediated METTL14 degradation regulates m6A mRNA modification to suppress ER proteotoxic liver disease
    1
    1. scibot 30 Nov 2021
      Cat# 003556

      DOI: 10.1016/j.molcel.2021.10.028

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1097276521009485
  38. Oct 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
    1
    1. scibot 27 Oct 2021
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2021.10.002

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1934590921004148
  40. Sep 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction
    1
    1. scibot 28 Sep 2021
      Jax: 003556

      DOI: 10.1016/j.immuni.2021.09.001

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1074761321003642
  42. Aug 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration
    1
    1. scibot 27 Aug 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.stem.2021.07.011

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:003556

      Curator comments: B6.Cg-Tg(Mx1-cre)1Cgn/J Mus musculus IMSR Cat# JAX:003556

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      RRIDCUR:Unresolved RRID:IMSR_JAX:003556 RRIDCUR:SyntaxError
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    sciencedirect.com/science/article/pii/S1934590921002964
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Aug 2021
      JAX:003556

      DOI: 10.1016/j.celrep.2018.12.030

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @scibot

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      RRID:IMSR_JAX:003556
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    ncbi.nlm.nih.gov/pmc/articles/PMC6362848/
  45. elifesciences.org elifesciences.org
    The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:003556

      DOI: 10.7554/eLife.51067

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    elifesciences.org/articles/51067
  46. Jul 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
    1
    1. scibot 30 Jul 2021
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2018.08.016

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Jmenke

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1934590918304016
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    2
    1. scibot 29 Jul 2021
      RRID:IMSR_JAX:003556

      DOI: 10.7554/eLife.32497

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @evieth

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      RRIDCUR:Duplicate RRIDCUR:Validated RRID:IMSR_JAX:003556
    2. scibot 29 Jul 2021
      RRID:IMSR_JAX:003556

      DOI: 10.7554/eLife.32497

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      Curator: @evieth

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    ncbi.nlm.nih.gov/pmc/articles/PMC5762159/
  49. Jun 2021
  50. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
      RRID:IMSR_JAX:003556

      DOI: 10.1158/2159-8290.CD-20-1353

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      Curator: @scibot

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  51. Apr 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations
    1
    1. scibot 30 Apr 2021
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.ccell.2021.03.012

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      Curator: @scibot

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1535610821001707
  53. www.sciencedirect.com www.sciencedirect.com
    Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging
    1
    1. scibot 13 Apr 2021
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2021.03.017

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      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1934590921001235
  54. Jan 2021
  55. www.sciencedirect.com www.sciencedirect.com
    OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy
    1
    1. scibot 07 Jan 2021
      JAX:003556

      DOI: 10.1016/j.celrep.2020.108579

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

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      RRID:IMSR_JAX:003556 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720315680
  56. Sep 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.devcel.2020.04.012

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Naa003

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1534580720303105
  58. www.sciencedirect.com www.sciencedirect.com
    Leukemogenic Chromatin Alterations Promote AML Leukemia Stem Cells via a KDM4C-ALKBH5-AXL Signaling Axis
    1
    1. scibot 17 Sep 2020
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2020.04.001

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1934590920301405
  59. www.sciencedirect.com www.sciencedirect.com
    ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms
    1
    1. scibot 04 Sep 2020
      Mx1-Cre mice (B6.Cg-Tg(Mx1-cre)1Cgn/J)

      DOI: 10.1016/j.celrep.2020.02.056

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S2211124720302242
  60. www.sciencedirect.com www.sciencedirect.com
    A FLCN-TFE3 Feedback Loop Prevents Excessive Glycogenesis and Phagocyte Activation by Regulating Lysosome Activity
    1
    1. scibot 03 Sep 2020
      Jackson laboratory003556

      DOI: 10.1016/j.celrep.2020.01.042

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S2211124720300668
  61. Jan 2020
  62. www.sciencedirect.com www.sciencedirect.com
    Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.stem.2019.08.003

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:003556 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1934590919303388
  63. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      JAX:003556

      DOI: 10.1016/j.celrep.2018.12.030

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @evieth

      SciCrunch record: JAX:003556

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      RRID:IMSR_JAX:003556 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124718319600
  64. www.sciencedirect.com www.sciencedirect.com
    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
    1
    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:003556

      DOI: 10.1016/j.ccell.2018.10.004

      Resource: (IMSR Cat# JAX_003556,RRID:IMSR_JAX:003556)

      Curator: @Jmenke

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      RRID:IMSR_JAX:003556 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818304707
  65. Nov 2018
  66. www.sciencedirect.com www.sciencedirect.com
    Mutant NPM1 Maintains the Leukemic State through HOX Expression
    1
    1. scibot 05 Nov 2018
      003556

      Curator: @Jmenke

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      RRID:IMSR_JAX:003556

      SciCrunch record: RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818303593
  67. www.sciencedirect.com www.sciencedirect.com
    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556
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    sciencedirect.com/science/article/pii/S1535610817305159
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    1
    1. scibot 05 Nov 2018
      Jackson Laboratories; stock 003556

      Curator: @bandrow

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      RRID:IMSR_JAX:003556

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    ncbi.nlm.nih.gov/pmc/articles/PMC5480394/
  69. Nov 2017
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioluminescence imaging of G protein-coupled receptor activation in living mice
    1
    1. scibot 08 Nov 2017
      003556

      Curator: @bandrow

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      RRID:IMSR_JAX:003556

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    ncbi.nlm.nih.gov/pmc/articles/PMC5660082/
  71. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
    1
    1. scibot 08 Nov 2017
      003556

      Curator: @Jmenke

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      RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867416314660
  72. www.sciencedirect.com www.sciencedirect.com
    Cholinergic Signals from the CNS Regulate G-CSF-Mediated HSC Mobilization from Bone Marrow via a Glucocorticoid Signaling Relay
    1
    1. scibot 08 Nov 2017
      003556

      Curator: @Jmenke

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      RRID:IMSR_JAX:003556

      SciCrunch record: RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1934590917300024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Memory Underlies Cell-Autonomous Heterogeneous Behavior of Hematopoietic Stem Cells
    1
    1. scibot 08 Nov 2017
      003556

      Curator: @bandrow

      Resource used:

      RRID:IMSR_JAX:003556

      SciCrunch record: RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556
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    ncbi.nlm.nih.gov/pmc/articles/PMC5510238/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations
    2
    1. scibot 08 Nov 2017
      IMSR_JAX:003556

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      RRID:IMSR_JAX:003556

      SciCrunch record: RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556
    2. scibot 08 Nov 2017
      IMSR_JAX:003556

      Curator: @chewbeccax

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      RRID:IMSR_JAX:003556

      SciCrunch record: RRID:IMSR_JAX:003556

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      RRID:IMSR_JAX:003556 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC5153248/