97 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    SPTLC3 regulates plasma membrane sphingolipid composition to facilitate hepatic gluconeogenesis
    1
    1. scibot 12 Dec 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2024.115054

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    sciencedirect.com/science/article/pii/S2211124724014050
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    Spatial organizations of heterochromatin underpin nuclear structural integrity of ventricular cardiomyocytes against mechanical stress
    1
    1. scibot 10 Dec 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2024.115048

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    sciencedirect.com/science/article/pii/S2211124724013998
  4. Nov 2024
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FAK is required for c-Met/β-catenin-driven hepatocarcinogenesis
    1
    1. scibot 22 Nov 2024
      003574

      DOI: 10.1002/hep.27402

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    pmc.ncbi.nlm.nih.gov/articles/PMC4280291/
  6. www.sciencedirect.com www.sciencedirect.com
    A β-hydroxybutyrate shunt pathway generates anti-obesity ketone metabolites
    1
    1. scibot 14 Nov 2024
      003574

      DOI: 10.1016/j.cell.2024.10.032

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    sciencedirect.com/science/article/pii/S0092867424012145
  7. Sep 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Paneth cell TNF signaling induces gut bacterial translocation and sepsis
    1
    1. scibot 10 Sep 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.chom.2024.08.007

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    sciencedirect.com/science/article/pii/S1931312824003147
  9. Aug 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome
    1
    1. scibot 13 Aug 2024
      Jackson Laboratories003574

      DOI: 10.1016/j.cmet.2024.07.003

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    sciencedirect.com/science/article/pii/S1550413124002742
  11. Jul 2024
  12. www.cell.com www.cell.com
    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
    1
    1. scibot 19 Jul 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2024.114400

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    cell.com/cell-reports/abstract/S2211-1247(24)00728-9
  13. 52.53.155.43 52.53.155.43
    research.0435-html.html
    1
    1. scibot 11 Jul 2024
      The Jackson Laboratory, 003574

      DOI: 10.34133/research.0435

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      Curator: @dhovakimyan1

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      RRID:IMSR_JAX:003574 DOI:10.34133/research.0435
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    52.53.155.43/a7f04caa88f9444036bc33f95ca42247b9d59475/research.0435-html.html
  14. Jun 2024
  15. www.sciencedirect.com www.sciencedirect.com
    FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance
    1
    1. scibot 18 Jun 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2021.108893

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    sciencedirect.com/science/article/pii/S2211124721002072
  16. May 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
    1
    1. scibot 17 May 2024
      The Jackson LaboratoryCat# 003574

      DOI: 10.7554/eLife.89912

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      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  18. www.sciencedirect.com www.sciencedirect.com
    Reprogramming tumor-associated macrophages and inhibiting tumor neovascularization by targeting MANF-HSF1-HSP70-1 pathway: An effective treatment for hepatocellular carcinoma
    1
    1. scibot 14 May 2024
      RRID: IMSR_JAX: 003574

      DOI: 10.1016/j.apsb.2024.05.001

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    sciencedirect.com/science/article/pii/S2211383524001795
  19. www.sciencedirect.com www.sciencedirect.com
    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
    1
    1. scibot 08 May 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2024.04.015

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    sciencedirect.com/science/article/pii/S1550413124001359
  20. Mar 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Transketolase promotes MAFLD by limiting inosine-induced mitochondrial activity
    1
    1. scibot 28 Mar 2024
      The Jackson LaboratoryCat#003574

      DOI: 10.1016/j.cmet.2024.03.003

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    sciencedirect.com/science/article/pii/S1550413124000822
  22. www.sciencedirect.com www.sciencedirect.com
    Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT
    1
    1. scibot 06 Mar 2024
      Jackson LaboratoriesCat# 003574

      DOI: 10.1016/j.celrep.2024.113881

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    sciencedirect.com/science/article/pii/S2211124724002092
  23. www.sciencedirect.com www.sciencedirect.com
    Hepatic malonyl-CoA synthesis restrains gluconeogenesis by suppressing fat oxidation, pyruvate carboxylation, and amino acid availability
    1
    1. scibot 06 Mar 2024
      Jackson Labs)Cat. #003574

      DOI: 10.1016/j.cmet.2024.02.004

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    sciencedirect.com/science/article/pii/S1550413124000500
  24. Feb 2024
  25. www.sciencedirect.com www.sciencedirect.com
    Gut-liver axis calibrates intestinal stem cell fitness
    1
    1. scibot 06 Feb 2024
      The Jackson LaboratoryCat# 003574

      DOI: 10.1016/j.cell.2024.01.001

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    sciencedirect.com/science/article/pii/S0092867424000035
  26. Jan 2024
  27. www.sciencedirect.com www.sciencedirect.com
    Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease
    1
    1. scibot 19 Jan 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2023.12.024

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    sciencedirect.com/science/article/pii/S1550413123004758
  28. www.sciencedirect.com www.sciencedirect.com
    Ergosterol peroxide blocks HDV infection as a novel entry inhibitor by targeting human NTCP receptor
    1
    1. scibot 07 Jan 2024
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.biopha.2023.116077

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    sciencedirect.com/science/article/pii/S0753332223018759
  29. www.sciencedirect.com www.sciencedirect.com
    Serine synthesis via reversed SHMT2 activity drives glycine depletion and acetaminophen hepatotoxicity in MASLD
    1
    1. scibot 06 Jan 2024
      The Jackson LaboratoryCat# 003574

      DOI: 10.1016/j.cmet.2023.12.013

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S1550413123004643
  30. www.sciencedirect.com www.sciencedirect.com
    Under peroxisome proliferation acyl-CoA oxidase coordinates with catalase to enhance ethanol metabolism
    1
    1. scibot 03 Jan 2024
      003574

      DOI: 10.1016/j.freeradbiomed.2023.08.016

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      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S0891584923005889
  31. Dec 2023
  32. www.sciencedirect.com www.sciencedirect.com
    Epinephrine inhibits PI3Kα via the Hippo kinases
    1
    1. scibot 20 Dec 2023
      Jackson laboratoriesStock No: 003574

      DOI: 10.1016/j.celrep.2023.113535

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124723015474
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic Huwe1 loss protects mice from non-alcoholic fatty liver disease through lipid metabolic rewiring
    1
    1. scibot 06 Dec 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.isci.2023.108405

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    ncbi.nlm.nih.gov/pmc/articles/PMC10692727/
  34. www.sciencedirect.com www.sciencedirect.com
    Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death
    1
    1. scibot 02 Dec 2023
      JAX:003574

      DOI: 10.1016/j.celrep.2023.113513

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    sciencedirect.com/science/article/pii/S2211124723015255
  35. Nov 2023
  36. link.springer.com link.springer.com
    Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice
    1
    1. scibot 25 Nov 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1038/s41598-023-47646-z

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    link.springer.com/article/10.1038/s41598-023-47646-z
  37. www.sciencedirect.com www.sciencedirect.com
    Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
    1
    1. scibot 10 Nov 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2023.113389

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    sciencedirect.com/science/article/pii/S2211124723014018
  38. Jul 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Kynurenine monooxygenase regulates inflammation during critical illness and recovery in experimental acute pancreatitis
    1
    1. scibot 21 Jul 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2023.112763

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    sciencedirect.com/science/article/pii/S221112472300774X
  40. www.sciencedirect.com www.sciencedirect.com
    Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
    1
    1. scibot 15 Jul 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.isci.2023.107199

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    sciencedirect.com/science/article/pii/S2589004223012762
  41. May 2023
  42. www.sciencedirect.com www.sciencedirect.com
    FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation
    1
    1. scibot 20 May 2023
      JAX:003574

      DOI: 10.1016/j.celrep.2023.112530

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    sciencedirect.com/science/article/pii/S2211124723005417
  43. link.springer.com link.springer.com
    Atransgenic mouse line for assaying tissue-specific changes in endoplasmic reticulum proteostasis
    1
    1. scibot 04 May 2023
      RRID:IMSR_JAX:003

      DOI: 10.1007/s11248-023-00349-7

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      Curator: @a5munoz

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    link.springer.com/article/10.1007/s11248-023-00349-7
  44. Apr 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice
    1
    1. scibot 08 Apr 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.neulet.2023.137236

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    sciencedirect.com/science/article/pii/S0304394023001933
  46. Jan 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
    1
    1. scibot 26 Jan 2023
      Stock No:003574

      DOI: 10.1016/j.devcel.2022.12.012

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    sciencedirect.com/science/article/pii/S1534580722008942
  48. www.sciencedirect.com www.sciencedirect.com
    Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation
    1
    1. scibot 10 Jan 2023
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cell.2022.11.029

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    sciencedirect.com/science/article/pii/S0092867422015045
  49. Nov 2022
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome
    1
    1. scibot 09 Nov 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1073/pnas.2210434119

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    ncbi.nlm.nih.gov/pmc/articles/PMC9636906/
  51. Oct 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Continuous sensing of IFNα by hepatic endothelial cells shapes a vascular antimetastatic barrier
    1
    1. scibot 27 Oct 2022
      JAX:003574

      DOI: 10.7554/eLife.80690

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    ncbi.nlm.nih.gov/pmc/articles/PMC9596162/
  53. 52.53.155.43 52.53.155.43
    Centriole signaling restricts hepatocyte ploidy to maintain liver integrity
    1
    1. scibot 27 Oct 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1101/gad.349727.122

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    52.53.155.43/27d2faf8da2c0ce1e6065d96eb324b873fb45bb8/Genes Dev.-2022-Sladky-843-56-html.html
  54. Sep 2022
  55. www.sciencedirect.com www.sciencedirect.com
    Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
    1
    1. scibot 16 Sep 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.molmet.2022.101589

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    sciencedirect.com/science/article/pii/S2212877822001582
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
    1. scibot 02 Sep 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  57. Aug 2022
  58. www.sciencedirect.com www.sciencedirect.com
    Arid1a mutation suppresses TGF-β signaling and induces cholangiocarcinoma
    1
    1. scibot 31 Aug 2022
      JAX:003574

      DOI: 10.1016/j.celrep.2022.111253

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    sciencedirect.com/science/article/pii/S2211124722010713
  59. www.sciencedirect.com www.sciencedirect.com
    Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis
    1
    1. scibot 04 Aug 2022
      JAX:003574

      DOI: 10.1016/j.cmet.2022.07.006

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    sciencedirect.com/science/article/pii/S1550413122003059
  60. Jun 2022
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tet2 deficiency drives liver microbiome dysbiosis triggering Tc1 cell autoimmune hepatitis
    1
    1. scibot 03 Jun 2022
      Jackson LaboratoryStock no.: 003574

      DOI: 10.1016/j.chom.2022.05.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC9841318/
  62. Apr 2022
  63. www.sciencedirect.com www.sciencedirect.com
    WWC proteins mediate LATS1/2 activation by Hippo kinases and imply a tumor suppression strategy
    1
    1. scibot 20 Apr 2022
      The Jackson Laboratory,#003574

      DOI: 10.1016/j.molcel.2022.03.027

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    sciencedirect.com/science/article/pii/S1097276522002659
  64. www.sciencedirect.com www.sciencedirect.com
    Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
    1
    1. scibot 07 Apr 2022
      Jackson laboratory003574

      DOI: 10.1016/j.cmet.2022.03.005

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    sciencedirect.com/science/article/pii/S1550413122000936
  65. Mar 2022
  66. www.nature.com www.nature.com
    CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
    1
    1. scibot 23 Mar 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1038/s41596-021-00677-0

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    nature.com/articles/s41596-021-00677-0
  67. Jan 2022
  68. www.sciencedirect.com www.sciencedirect.com
    Apolipoprotein E derived from CD11c+ cells ameliorates atherosclerosis
    1
    1. scibot 12 Jan 2022
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.isci.2021.103677

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    sciencedirect.com/science/article/pii/S2589004221016473
  69. Dec 2021
  70. www.sciencedirect.com www.sciencedirect.com
    TOX4, an insulin receptor-independent regulator of hepatic glucose production, is activated in diabetic liver
    1
    1. scibot 21 Dec 2021
      Stock#003574

      DOI: 10.1016/j.cmet.2021.11.013

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    sciencedirect.com/science/article/pii/S1550413121005416
  71. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
    1
    1. scibot 21 Dec 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1038/s41467-021-27452-9

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    nature.com/articles/s41467-021-27452-9
  72. Nov 2021
  73. www.sciencedirect.com www.sciencedirect.com
    APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis
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    1. scibot 09 Nov 2021
      Stock#003574

      DOI: 10.1016/j.immuni.2021.10.004

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    sciencedirect.com/science/article/pii/S1074761321004106
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
    1
    1. scibot 05 Nov 2021
      RRID:IMSR_JAX:003574

      DOI: 10.7554/eLife.57462

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  75. Oct 2021
  76. www.embopress.org www.embopress.org
    Reprogramming of glucocorticoid receptor function by hypoxia
    1
    1. scibot 27 Oct 2021
      RRID:IMSR_JAX:003574

      DOI: 10.15252/embr.202153083

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    embopress.org/doi/full/10.15252/embr.202153083
  77. www.sciencedirect.com www.sciencedirect.com
    Glycogen accumulation and phase separation drives liver tumor initiation
    1
    1. scibot 22 Oct 2021
      Stock No: 003574

      DOI: 10.1016/j.cell.2021.10.001

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    sciencedirect.com/science/article/pii/S0092867421011752
  78. www.sciencedirect.com www.sciencedirect.com
    Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase
    1
    1. scibot 08 Oct 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.celrep.2021.109785

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    sciencedirect.com/science/article/pii/S2211124721012444
  79. Sep 2021
  80. www.sciencedirect.com www.sciencedirect.com
    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
    1
    1. scibot 08 Sep 2021
      Stock No: 003574

      DOI: 10.1016/j.celrep.2021.109659

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    sciencedirect.com/science/article/pii/S2211124721011037
  81. Aug 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Hepatic nitric oxide synthase 1 adaptor protein regulates glucose homeostasis and hepatic insulin sensitivity in obese mice depending on its PDZ binding domain
    1
    1. scibot 01 Aug 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.ebiom.2019.08.033

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    sciencedirect.com/science/article/pii/S2352396419305584
  83. Jul 2021
  84. www.sciencedirect.com www.sciencedirect.com
    Activin E Controls Energy Homeostasis in Both Brown and White Adipose Tissues as a Hepatokine
    2
    1. scibot 30 Jul 2021
      JAX:003574

      DOI: 10.1016/j.celrep.2018.10.008

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      Curator: @evieth

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      RRID:IMSR_JAX:003574 RRIDCUR:Duplicate RRIDCUR:Validated
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      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2018.10.008

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    sciencedirect.com/science/article/pii/S2211124718315717
  85. www.sciencedirect.com www.sciencedirect.com
    GPR146 Deficiency Protects against Hypercholesterolemia and Atherosclerosis
    1
    1. scibot 29 Jul 2021
      RRID: IMSR_JAX:003574

      DOI: 10.1016/j.cell.2019.10.034

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    sciencedirect.com/science/article/pii/S0092867419312115
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diabetes reversal by inhibition of the low molecular weight tyrosine phosphatase
    1
    1. scibot 27 Jul 2021
      003574

      DOI: 10.1038/nchembio.2344

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    ncbi.nlm.nih.gov/pmc/articles/PMC5435566/
  87. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 27 Jul 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.cell.2019.02.013

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      RRID:IMSR_JAX:003574 RRIDCUR:Unresolved
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    sciencedirect.com/science/article/pii/S009286741930162X
  88. www.sciencedirect.com www.sciencedirect.com
    Time-Restricted Feeding Prevents Obesity and Metabolic Syndrome in Mice Lacking a Circadian Clock
    1
    1. scibot 27 Jul 2021
      RRID:MSR_JAX:003574

      DOI: 10.1016/j.cmet.2018.08.004

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    sciencedirect.com/science/article/pii/S1550413118305059
  89. www.sciencedirect.com www.sciencedirect.com
    Combined glucocorticoid resistance and hyperlactatemia contributes to lethal shock in sepsis
    1
    1. scibot 24 Jul 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2021.07.002

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    sciencedirect.com/science/article/pii/S1550413121003181
  90. Jun 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Hepatocyte membrane potential regulates serum insulin and insulin sensitivity by altering hepatic GABA release
    1
    1. scibot 30 Jun 2021
      JAX stock 003574

      DOI: 10.1016/j.celrep.2021.109298

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    sciencedirect.com/science/article/pii/S2211124721006744
  92. www.sciencedirect.com www.sciencedirect.com
    Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
    1
    1. scibot 19 Jun 2021
      Cat#003574

      DOI: 10.1016/j.cmet.2021.05.019

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    sciencedirect.com/science/article/pii/S1550413121002709
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells
    1
    1. scibot 17 Jun 2021
      JAX:003574

      DOI: 10.1371/journal.ppat.1009593

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172060/
  94. May 2021
  95. www.sciencedirect.com www.sciencedirect.com
    PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation
    1
    1. scibot 08 May 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.molcel.2021.01.032

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    sciencedirect.com/science/article/pii/S1097276521000526
  96. www.sciencedirect.com www.sciencedirect.com
    Aging Suppresses Sphingosine-1-Phosphate Chaperone ApoM in Circulation Resulting in Maladaptive Organ Repair
    1
    1. scibot 07 May 2021
      RRID:IMSR_JAX

      DOI: 10.1016/j.devcel.2020.05.024

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    sciencedirect.com/science/article/pii/S1534580720304135
  97. Apr 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intercellular Transmission of Hepatic ER Stress in Obesity Disrupts Systemic Metabolism
    1
    1. scibot 30 Apr 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2020.11.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC7858244/
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    Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction
    1
    1. scibot 29 Apr 2021
      003574

      DOI: 10.1016/j.cmet.2020.05.012

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    sciencedirect.com/science/article/pii/S1550413120302515
  100. www.sciencedirect.com www.sciencedirect.com
    TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
    1
    1. scibot 29 Apr 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2020.10.010

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    sciencedirect.com/science/article/pii/S155041312030543X
  101. www.sciencedirect.com www.sciencedirect.com
    Identification of ALK in Thinness
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    1. scibot 23 Apr 2021
      Stock No 003574

      DOI: 10.1016/j.cell.2020.04.034

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    sciencedirect.com/science/article/pii/S0092867420304979
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    The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine
    1
    1. scibot 22 Apr 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2021.03.025

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    sciencedirect.com/science/article/pii/S1550413121001662
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    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
    1
    1. scibot 17 Apr 2021
      Stock No: 003574

      DOI: 10.1016/j.ccell.2020.05.018

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    sciencedirect.com/science/article/pii/S1535610820302683
  104. Mar 2021
  105. www.sciencedirect.com www.sciencedirect.com
    FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance
    1
    1. scibot 24 Mar 2021
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.celrep.2021.108893

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    sciencedirect.com/science/article/pii/S2211124721002072
  106. Feb 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
    1
    1. scibot 28 Feb 2021
      JAX:003574

      DOI: 10.1016/j.ccell.2017.05.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC7909318/
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism
    1
    1. scibot 27 Feb 2021
      RRID:IMSR_JAX:003574

      DOI: 10.7554/eLife.59258

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    ncbi.nlm.nih.gov/pmc/articles/PMC7723411/
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    Inhibition of FGF10-ERK signal activation suppresses intraductal papillary neoplasm of the bile duct and its associated carcinomas
    1
    1. scibot 24 Feb 2021
      Stock# 003574

      DOI: 10.1016/j.celrep.2021.108772

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @Naa003

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    sciencedirect.com/science/article/pii/S2211124721000851
  110. Jan 2021
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
    1
    1. scibot 13 Jan 2021
      JAX:003574

      DOI: 10.1101/gad.344556.120

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @evieth

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      RRID:IMSR_JAX:003574 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7778269/
  112. Dec 2020
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
    1
    1. scibot 07 Dec 2020
      RRID:IMSR_JAX:003574

      DOI: 10.7554/eLife.58069

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
  114. Sep 2020
  115. www.pnas.org www.pnas.org
    JNK-mediated disruption of bile acid homeostasis promotes intrahepatic cholangiocarcinoma
    1
    1. scibot 13 Sep 2020
      RRID:IMSR_JAX:003574

      DOI: 10.1073/pnas.2002672117

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

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    pnas.org/content/117/28/16492
  116. www.sciencedirect.com www.sciencedirect.com
    Novel aspects of glutamine synthetase in ammonia homeostasis
    1
    1. scibot 06 Sep 2020
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.neuint.2020.104809

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    sciencedirect.com/science/article/pii/S019701862030200X
  117. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression
    1
    1. scibot 04 Sep 2020
      B6.Cg‐Tg(Alb‐cre)21Mgn/J

      DOI: 10.1002/ijc.32787

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:003574

      Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Missing
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    onlinelibrary.wiley.com/doi/10.1002/ijc.32787
  118. www.sciencedirect.com www.sciencedirect.com
    JARID1a Ablation in the Liver Alters Systemic Metabolism and Adaptation to Feeding
    1
    1. scibot 03 Sep 2020
      The Jackson Laboratorystock 003574

      DOI: 10.1016/j.celrep.2020.107668

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S2211124720306215
  119. elifesciences.org elifesciences.org
    Ovariectomy uncouples lifespan from metabolic health and reveals a sex-hormone-dependent role of hepatic mTORC2 in aging
    1
    1. scibot 03 Sep 2020
      RRID:IMSR_JAX:003574

      DOI: 10.7554/eLife.56177

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @evieth

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    elifesciences.org/articles/56177
  120. Aug 2020
  121. advances.sciencemag.org advances.sciencemag.org
    Control of protein function through oxidation and reduction of persulfidated states
    1
    1. scibot 14 Aug 2020
      JAX#003574

      DOI: 10.1126/sciadv.aax8358

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:003574

      Curator comments: B6.Cg-Speer6-ps1Tg(Alb-cre)21Mgn/J Mus musculus IMSR Cat# JAX:003574

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    advances.sciencemag.org/content/6/1/eaax8358
  122. Jan 2020
  123. www.sciencedirect.com www.sciencedirect.com
    Serum Amyloid A Proteins Induce Pathogenic Th17 Cells and Promote Inflammatory Disease
    1
    1. scibot 13 Jan 2020
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cell.2019.11.026

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @ethanbadger

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      RRID:IMSR_JAX:003574 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419312838
  124. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:003574

      DOI: 10.1016/j.cmet.2019.03.001

      Resource: (IMSR Cat# JAX_003574,RRID:IMSR_JAX:003574)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1550413119301299
  125. Nov 2018
  126. www.sciencedirect.com www.sciencedirect.com
    γ-Secretase Inhibition Lowers Plasma Triglyceride-Rich Lipoproteins by Stabilizing the LDL Receptor
    1
    1. scibot 05 Nov 2018
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1550413118301219
  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Endotoxin Delivery Protein HMGB1 Mediates Caspase-11-Dependent Lethality in Sepsis
    1
    1. scibot 05 Nov 2018
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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    pmc.ncbi.nlm.nih.gov/articles/PMC6300139/
  128. www.sciencedirect.com www.sciencedirect.com
    Small RNAs Are Trafficked from the Epididymis to Developing Mammalian Sperm
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574

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    sciencedirect.com/science/article/pii/S1534580718305409
  129. www.sciencedirect.com www.sciencedirect.com
    Lipid Peroxidation Drives Gasdermin D-Mediated Pyroptosis in Lethal Polymicrobial Sepsis
    1
    1. scibot 05 Nov 2018
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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    sciencedirect.com/science/article/pii/S1931312818302634
  130. www.sciencedirect.com www.sciencedirect.com
    Selective Inhibition of FOXO1 Activator/Repressor Balance Modulates Hepatic Glucose Handling
    1
    1. scibot 05 Nov 2018
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S009286741731139X
  131. www.sciencedirect.com www.sciencedirect.com
    Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling
    1
    1. scibot 05 Nov 2018
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S1535610818302174
  132. www.sciencedirect.com www.sciencedirect.com
    AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574

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    sciencedirect.com/science/article/pii/S1550413118301323
  133. journals.sagepub.com journals.sagepub.com
    Untitled document
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:003574

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    journals.sagepub.com/doi/full/10.1369/0022155417749828
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    1
    1. scibot 05 Nov 2018
      Jackson Laboratories; stock 003574

      Curator: @bandrow

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      RRID:IMSR_JAX:003574

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    ncbi.nlm.nih.gov/pmc/articles/PMC5480394/
  135. Nov 2017
  136. www.sciencedirect.com www.sciencedirect.com
    The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity
    1
    1. scibot 08 Nov 2017
      003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

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    sciencedirect.com/science/article/pii/S1550413117304886
  137. www.sciencedirect.com www.sciencedirect.com
    Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS
    1
    1. scibot 08 Nov 2017
      JAX:003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

      SciCrunch record: RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610817302027
  138. www.sciencedirect.com www.sciencedirect.com
    Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    1
    1. scibot 08 Nov 2017
      JAX stock 003574

      Curator: @Jmenke

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      RRID:IMSR_JAX:003574

      SciCrunch record: RRID:IMSR_JAX:003574

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      RRID:IMSR_JAX:003574 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S0092867417305925