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Cell-type-focused compound screen in human organoids reveals CK1 inhibition protects cone photoreceptors from death

1
1. scibot 31 Mar 2026
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1016/j.neuron.2026.02.024
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0896627326001297
Dec 2025
www.sciencedirect.com www.sciencedirect.com

Female sex is a risk factor for exacerbated lipid peroxidation and disease in murine retinitis pigmentosa

1
1. scibot 23 Dec 2025
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1016/j.redox.2025.103987
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2213231725005002
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Metipranolol promotes structure and function of retinal photoreceptors in the rd10 mouse model of human retinitis pigmentosa

1
1. scibot 01 Nov 2025
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1111/jnc.14613
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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pmc.ncbi.nlm.nih.gov/articles/PMC12554146/
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

AAV2-PDE6B restores retinal structure and function in the retinal degeneration 10 mouse model of retinitis pigmentosa by promoting phototransduction and inhibiting apoptosis

1
1. scibot 30 Jan 2025
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.4103/NRR.NRR-D-23-01301
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11759017/
Dec 2024
www.researchsquare.com www.researchsquare.com

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1
1. scibot 28 Dec 2024
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.21203/rs.3.rs-1885484/v1
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
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researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
www.sciencedirect.com www.sciencedirect.com

Layer-specific anatomical and physiological features of the retina’s neurovascular unit

1
1. scibot 17 Dec 2024
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1016/j.cub.2024.11.023
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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sciencedirect.com/science/article/pii/S0960982224015641
Nov 2024
elifesciences.org elifesciences.org

AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa

1
1. scibot 28 Nov 2024
  
  in Public
  
  MGI:2388259
  
  DOI: 10.7554/eLife.66240
  
  Resource: None
  
  Curator: @AlecAsdourian
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Unresolved
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elifesciences.org/articles/66240
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A combination treatment based on drug repurposing demonstrates mutation-agnostic efficacy in pre-clinical retinopathy models

1
1. scibot 18 Jul 2024
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1038/s41467-024-50033-5
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11251169/
May 2024
www.nature.com www.nature.com

Prominin 1 is crucial for the early development of photoreceptor outer segments

1
1. scibot 08 May 2024
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1038/s41598-024-60989-5
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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nature.com/articles/s41598-024-60989-5
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Trans-Sclera Electrical Stimulation Improves Retinal Function in a Mouse Model of Retinitis Pigmentosa

1
1. scibot 01 Dec 2022
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.3390/life12111917
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9693292/
Apr 2022
link.springer.com link.springer.com

Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones

1
1. scibot 14 Apr 2022
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1186/s12915-022-01280-9
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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link.springer.com/article/10.1186/s12915-022-01280-9
Oct 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Wolfberry-derived zeaxanthin dipalmitate delays retinal degeneration in a mouse model of retinitis pigmentosa through modulating STAT3, CCL2 and MAPK pathways

1
1. scibot 20 Oct 2021
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1111/jnc.15472
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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onlinelibrary.wiley.com/doi/10.1111/jnc.15472
Sep 2021
elifesciences.org elifesciences.org

Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa

1
1. scibot 14 Sep 2021
  
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  JAX:004297
  
  DOI: 10.7554/eLife.57245
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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elifesciences.org/articles/57245
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Visual Cortex Engagement in Retinitis Pigmentosa

1
1. scibot 14 Sep 2021
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.3390/ijms22179412
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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ncbi.nlm.nih.gov/pmc/articles/PMC8431500/
Aug 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

1
1. scibot 10 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:004297
  
  DOI: 10.1111/jnc.14613
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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onlinelibrary.wiley.com/doi/full/10.1111/jnc.14613
www.frontiersin.org www.frontiersin.org

Untitled document

1
1. scibot 05 Aug 2021
  
  in Public
  
  JAX:004297
  
  DOI: 10.3389/fncel.2015.00390
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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frontiersin.org/article/10.3389/fncel.2015.00390/full
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Blood-retina barrier failure and vision loss in neuron-specific degeneration

1
1. scibot 02 Aug 2021
  
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  RRID:IMSR_JAX:004297
  
  DOI: 10.1172/jci.insight.126747
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297
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ncbi.nlm.nih.gov/pmc/articles/PMC6538333/
Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Disruption in dopaminergic innervation during photoreceptor degeneration

1
1. scibot 27 Jul 2021
  
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  Jax:004297
  
  DOI: 10.1002/cne.23899
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Unresolved
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onlinelibrary.wiley.com/doi/10.1002/cne.23899/full
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased phosphorylation of Cx36 gap junctions in the AII amacrine cells of RD retina

1
1. scibot 27 Jul 2021
  
  in Public
  
  IMSR_JAX:004297
  
  DOI: 10.3389/fncel.2015.00390
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Unresolved RRIDCUR:Incorrect
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RRIDCUR:Incorrect

RRIDCUR:Unresolved

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC4589668/
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bayesian inference for biophysical neuron models enables stimulus optimization for retinal neuroprosthetics

1
1. scibot 26 Nov 2020
  
  in Public
  
  RRID:IMSR_JAX:004297
  
  DOI: 10.7554/eLife.54997
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Validated
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RRID:IMSR_JAX:004297

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ncbi.nlm.nih.gov/pmc/articles/PMC7673784/
Oct 2020
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Unmasking inhibition prolongs neuronal function in retinal degeneration mouse model

1
1. scibot 03 Oct 2020
  
  in Public
  
  B6.CXB1‐Pde6b rd10/J
  
  DOI: 10.1096/fj.202001315RR
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
  Curator comments: B6.CXB1-Pde6brd10/J Mus musculus IMSR Cat# JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Missing
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RRID:IMSR_JAX:004297

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faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.202001315RR
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Preservation of Visual Cortex Plasticity in Retinitis Pigmentosa

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:004297
  
  DOI: 10.1016/j.neuroscience.2019.10.045
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Validated
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RRID:IMSR_JAX:004297

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sciencedirect.com/science/article/pii/S0306452219307444
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:004297
  
  DOI: 10.1016/j.neuron.2019.02.015
  
  Resource: (IMSR Cat# JAX_004297,RRID:IMSR_JAX:004297)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Validated
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RRID:IMSR_JAX:004297

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sciencedirect.com/science/article/pii/S0896627319301242
Nov 2017
www.jneurosci.org www.jneurosci.org

Suppression of Microglial Activation Is Neuroprotective in a Mouse Model of Human Retinitis Pigmentosa

1
1. scibot 08 Nov 2017
  
  in Public
  
  rd10 mice
  
  Curator: @jcabotaj
  
  Resource used:
  
  RRID:IMSR_JAX:004297
  
  SciCrunch record: RRID:IMSR_JAX:004297
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:004297 RRIDCUR:Missing
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RRID:IMSR_JAX:004297

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scibot

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jneurosci.org/content/34/24/8139.long