51 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    GDF15-GFRAL signaling drives weight loss and lipid metabolism in mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 12 Dec 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.bbi.2024.12.010

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    sciencedirect.com/science/article/pii/S0889159124007396
  3. www.sciencedirect.com www.sciencedirect.com
    Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration
    1
    1. scibot 10 Dec 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.celrep.2024.115046

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    sciencedirect.com/science/article/pii/S2211124724013974
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol for handling and using SOD1 mice for amyotrophic lateral sclerosis pre-clinical studies
    1
    1. scibot 06 Dec 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.xpro.2024.103459

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    sciencedirect.com/science/article/pii/S2666166724006245
  5. Aug 2024
  6. www.mdpi.com www.mdpi.com
    An Intercellular Flow of Glutathione Regulated by Interleukin 6 Links Astrocytes and the Liver in the Pathophysiology of Amyotrophic Lateral Sclerosis
    1
    1. scibot 02 Aug 2024
      004435

      DOI: 10.3390/antiox10122007

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    mdpi.com/2076-3921/10/12/2007/htm
  7. Jun 2024
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ebselen analogues delay disease onset and its course in fALS by on-target SOD-1 engagement
    1
    1. scibot 02 Jun 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1038/s41598-024-62903-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11130262/
  9. May 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Targeting low levels of MIF expression as a potential therapeutic strategy for ALS
    1
    1. scibot 07 May 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.xcrm.2024.101546

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    sciencedirect.com/science/article/pii/S2666379124002386
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TwinF interface inhibitor FP802 stops loss of motor neurons and mitigates disease progression in a mouse model of ALS
    2
    1. scibot 12 Mar 2024
      Jackson LaboratoryLine#004435

      DOI: 10.1016/j.xcrm.2024.101413

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    2. scibot 12 Mar 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.xcrm.2024.101413

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897598/
  13. Feb 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Communication defects with astroglia contribute to early impairments in the motor cortex plasticity of SOD1G93A mice
    1
    1. scibot 15 Feb 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.nbd.2024.106435

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    sciencedirect.com/science/article/pii/S0969996124000342
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic background variation impacts microglial heterogeneity and disease progression in amyotrophic lateral sclerosis model mice
    1
    1. scibot 08 Feb 2024
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.isci.2024.108872

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    ncbi.nlm.nih.gov/pmc/articles/PMC10839647/
  16. Jan 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Sigma-1 receptor maintains ATAD3A as a monomer to inhibit mitochondrial fragmentation at the mitochondria-associated membrane in amyotrophic lateral sclerosis
    1
    1. scibot 02 Jan 2024
      B6.Cg-Tg(SOD1*G93A)1Gur/J

      DOI: 10.1016/j.nbd.2023.106031

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    sciencedirect.com/science/article/pii/S0969996123000451
  18. Sep 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS
    1
    1. scibot 17 Sep 2023
      RRID:IMSR_JAX:004435

      DOI: 10.1186/s13578-023-01116-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10498603/
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intranasal neuropeptide Y1 receptor antagonism improves motor deficits in symptomatic SOD1 ALS mice
    1
    1. scibot 06 Sep 2023
      RRID:IMSR_JAX:004435

      DOI: 10.1002/acn3.51885

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    onlinelibrary.wiley.com/doi/10.1002/acn3.51885
  21. Jul 2023
  22. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 13 Jul 2023
      RRID:IMSR_JAX:004435

      DOI: 10.1111/jnc.15906

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15906
  23. Jun 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis
    1
    1. scibot 03 Jun 2023
      RRID:IMSR_JAX:004435

      DOI: 10.4103/1673-5374.367929

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    ncbi.nlm.nih.gov/pmc/articles/PMC10233787/
  25. May 2023
  26. www.mdpi.com www.mdpi.com
    Differential NPY-Y1 Receptor Density in the Motor Cortex of ALS Patients and Familial Model of ALS
    1
    1. scibot 06 May 2023
      004435

      DOI: 10.3390/brainsci11080969

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    mdpi.com/2076-3425/11/8/969/htm
  27. Jan 2023
  28. journals.lww.com journals.lww.com
    A candidate protective factor in amyotrophic lateral... : Neural Regeneration Research
    1
    1. scibot 19 Jan 2023
      RRID:IMSR_JAX:004435

      DOI: 10.4103/1673-5374.357916

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    journals.lww.com/nrronline/Fulltext/2023/07000/A_candidate_protective_factor_in_amyotrophic.26.aspx
  29. Jun 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Blocking Immune Cell infiltration of the Central Nervous System to Tame Neuroinflammation in Amyotrophic Lateral Sclerosis
    1
    1. scibot 15 Jun 2022
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.bbi.2022.06.004

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    sciencedirect.com/science/article/pii/S0889159122001568
  31. Apr 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPA receptor and RNA processing gene dysregulation are early determinants of selective motor neuron vulnerability in a mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 22 Apr 2022
      RRID:IMSR_JAX:004435

      DOI: 10.1093/braincomms/fcac081

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    ncbi.nlm.nih.gov/pmc/articles/PMC9016138/
  33. Mar 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Unique molecular features and cellular responses differentiate two populations of motor cortical layer 5b neurons in a preclinical model of ALS
    1
    1. scibot 23 Mar 2022
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.celrep.2022.110556

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    sciencedirect.com/science/article/pii/S221112472200300X
  35. www.nature.com www.nature.com
    Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1G93A mice
    1
    1. scibot 23 Mar 2022
      RRID:IMSR_JAX:00443538

      DOI: 10.1038/s41598-022-08455-y

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    nature.com/articles/s41598-022-08455-y
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Murine glial progenitor cells transplantation and synthetic PreImplantation Factor (sPIF) reduces inflammation and early motor impairment in ALS mice
    1
    1. scibot 11 Mar 2022
      RRID:IMSR_JAX:004435

      DOI: 10.1038/s41598-022-08064-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC8901633/
  37. Feb 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphoinositide-3-kinase regulatory subunit 4 participates in the occurrence and development of amyotrophic lateral sclerosis by regulating autophagy
    1
    1. scibot 05 Feb 2022
      JAX:004435

      DOI: 10.4103/1673-5374.330621

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    ncbi.nlm.nih.gov/pmc/articles/PMC8771104/
  39. Dec 2021
  40. www.sciencedirect.com www.sciencedirect.com
    KLF15 overexpression in myocytes fails to ameliorate ALS-related pathology or extend the lifespan of SOD1G93A mice
    1
    1. scibot 15 Dec 2021
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.nbd.2021.105583

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    sciencedirect.com/science/article/pii/S0969996121003326
  41. Oct 2021
  42. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 20 Oct 2021
      RRID:IMSR_JAX:004435

      DOI: 10.1111/bph.15665

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15665
  43. Aug 2021
  44. www.jneurosci.org www.jneurosci.org
    Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
    1
    1. scibot 07 Aug 2021
      RRID:IMSR_JAX:004435

      DOI: 10.1523/JNEUROSCI.2462-16.2016

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    jneurosci.org/content/37/6/1413
  45. Jul 2021
  46. www.nature.com www.nature.com
    Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity
    1
    1. scibot 29 Jul 2021
      004435

      DOI: 10.1038/s41593-019-0479-z

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    nature.com/articles/s41593-019-0479-z
  47. www.mdpi.com www.mdpi.com
    Assessment of Immunological Potential of Glial Restricted Progenitor Graft In Vivo—Is Immunosuppression Mandatory?
    1
    1. scibot 20 Jul 2021
      RRID:IMSR_JAX:004435

      DOI: 10.3390/cells10071804

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    mdpi.com/2073-4409/10/7/1804/htm
  48. Sep 2020
  49. www.nature.com www.nature.com
    Natural killer cells modulate motor neuron-immune cell cross talk in models of Amyotrophic Lateral Sclerosis
    1
    1. scibot 26 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1038/s41467-020-15644-8

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    nature.com/articles/s41467-020-15644-8
  50. www.sciencedirect.com www.sciencedirect.com
    The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice
    1
    1. scibot 16 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.neuron.2020.03.005

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    sciencedirect.com/science/article/pii/S0896627320301914
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models
    1
    1. scibot 15 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1111/jnc.15119

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15119
  52. www.sciencedirect.com www.sciencedirect.com
    Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis
    1
    1. scibot 13 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.ebiom.2020.102980

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    sciencedirect.com/science/article/pii/S235239642030356X
  53. www.sciencedirect.com www.sciencedirect.com
    6-Deoxyjacareubin, a natural compound preventing hypoxia-induced cell death, ameliorates neurodegeneration in a mouse model of familial amyotrophic lateral sclerosis
    1
    1. scibot 10 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1016/j.neures.2020.02.011

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    sciencedirect.com/science/article/pii/S0168010219306522
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen receptor antagonism accelerates disease onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis
    1
    1. scibot 09 Sep 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1111/bph.14657

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    ncbi.nlm.nih.gov/pmc/articles/PMC6555856/
  55. www.sciencedirect.com www.sciencedirect.com
    Spinal Motoneuron TMEM16F Acts at C-boutons to Modulate Motor Resistance and Contributes to ALS Pathogenesis
    1
    1. scibot 03 Sep 2020
      The Jackson LaboratoryStock No. 004435

      DOI: 10.1016/j.celrep.2020.02.001

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    sciencedirect.com/science/article/pii/S2211124720301558
  56. Jan 2020
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons
    1
    1. scibot 13 Jan 2020
      JAX:004435

      DOI: 10.7554/eLife.44423

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    ncbi.nlm.nih.gov/pmc/articles/PMC6594754/
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 12 Jan 2020
      RRID:IMSR_JAX:004435

      DOI: 10.1111/bph.14657

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14657
  59. Nov 2018
  60. www.sciencedirect.com www.sciencedirect.com
    Ca2+-activated K+ channels modulate microglia affecting motor neuron survival in hSOD1G93A mice
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004435

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S0889159118302885
  61. elifesciences.org elifesciences.org
    Untitled document
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      RRID:IMSR_JAX:004435

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    elifesciences.org/articles/34375
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      RRID:IMSR_JAX:004435

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5837562/
  63. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1‐linked amyotrophic lateral sclerosis mice
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004435

      Curator: @anp055

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14285/full
  64. www.sciencedirect.com www.sciencedirect.com
    Impact of peripheral immune status on central molecular responses to facial nerve axotomy
    1
    1. scibot 05 Nov 2018
      RRID:IMSR_JAX:004435

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    sciencedirect.com/science/article/pii/S0889159117304580
  65. Nov 2017
  66. www.jneurosci.org www.jneurosci.org
    SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions
    1
    1. scibot 08 Nov 2017
      004435

      Curator: @bandrow

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    jneurosci.org/content/37/17/4493
  67. www.sciencedirect.com www.sciencedirect.com
    Releasing Syntaphilin Removes Stressed Mitochondria from Axons Independent of Mitophagy under Pathophysiological Conditions
    1
    1. scibot 08 Nov 2017
      JAX: 004435

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0896627317302970
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early intrinsic hyperexcitability does not contribute to motoneuron degeneration in amyotrophic lateral sclerosis
    2
    1. scibot 08 Nov 2017
      IMSR_JAX:004435

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      RRID:IMSR_JAX:004435
    2. scibot 08 Nov 2017
      IMSR_JAX:004435

      Curator: @jcabotaj

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    ncbi.nlm.nih.gov/pmc/articles/PMC4227046/
  69. www.jneurosci.org www.jneurosci.org
    Muscle Fibers Secrete FGFBP1 to Slow Degeneration of Neuromuscular Synapses during Aging and Progression of ALS
    2
    1. scibot 08 Nov 2017
      IMSR_JAX:004435

      Curator: @chewbeccax

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    2. scibot 08 Nov 2017
      IMSR_JAX:004435

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    jneurosci.org/content/37/1/70.long
  70. www.nature.com www.nature.com
    Calretinin and Neuropeptide Y interneurons are differentially altered in the motor cortex of the SOD1G93A mouse model of ALS
    1
    1. scibot 08 Nov 2017
      http://www.jax.org/strain/004435)]

      Curator: @bandrow

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    nature.com/articles/srep44461
  71. www.jneurosci.org www.jneurosci.org
    Targeting Extracellular Cyclophilin A Reduces Neuroinflammation and Extends Survival in a Mouse Model of Amyotrophic Lateral Sclerosis
    1
    1. scibot 08 Nov 2017
      IMSR_JAX:004435

      Curator: @chewbeccax

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    jneurosci.org/content/37/6/1413
  72. www.sciencedirect.com www.sciencedirect.com
    The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes
    1
    1. scibot 08 Nov 2017
      IMSR: B6.Cg-Tg (SOD1*G93A) 1Gur/J

      Curator: @jcabotaj

      Curator note: wrong format used in paper

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    sciencedirect.com/science/article/pii/S0969996114001727