27 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    Stochastic misfolding drives the emergence of distinct α-synuclein strains
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    sciencedirect.com/science/article/pii/S0896627326000401
  3. Feb 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial transcriptomics reveals the molecular signatures of prodromal and advanced α-synucleinopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12927100/
  5. Nov 2025
  6. link.springer.com link.springer.com
    Attenuating α-synuclein pathology in mice with in situ engineered astrocytes
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    link.springer.com/article/10.1186/s40035-025-00518-0
  7. Sep 2025
  8. www.nature.com www.nature.com
    N-type Ca2+ channels mediate the stimuli-dependent α-synuclein secretion in mouse striatum
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    nature.com/articles/s41531-025-01110-z
  9. Apr 2025
  10. www.biorxiv.org www.biorxiv.org
    Detection of misfolded proteins in neurodegenerative disease models with a highly sensitive chemiluminescence probe
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    biorxiv.org/content/10.1101/2025.04.12.648090v1
  11. Feb 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Oligodendrocytes drive neuroinflammation and neurodegeneration in Parkinson’s disease via the prosaposin-GPR37-IL-6 axis
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    sciencedirect.com/science/article/pii/S2211124725000373
  13. Jan 2025
  14. www.sciencedirect.com www.sciencedirect.com
    G6PD deficiency triggers dopamine loss and the initiation of Parkinson’s disease pathogenesis
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    sciencedirect.com/science/article/pii/S2211124724015298
  15. Nov 2024
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The role of polo‐like kinases 2 in the proteasomal and lysosomal degradation of alpha‐synuclein in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11580719/
  17. Jul 2024
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthesis and Characterization of Click Chemical Probes for Single-Cell Resolution Detection of Epichaperomes in Neurodegenerative Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC11201208/
  19. Jun 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-synuclein aggregates are phosphatase resistant
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    ncbi.nlm.nih.gov/pmc/articles/PMC11141014/
  21. May 2024
  22. www.sciencedirect.com www.sciencedirect.com
    Nuclear aggregates of NONO/SFPQ and A-to-I-edited RNA in Parkinson’s disease and dementia with Lewy bodies
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    sciencedirect.com/science/article/pii/S0896627324003283
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha-synuclein aggregates are phosphatase resistant
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030248/
  24. Feb 2024
  25. link.springer.com link.springer.com
    α-Synuclein oligomers potentiate neuroinflammatory NF-κB activity and induce Cav3.2 calcium signaling in astrocytes
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    link.springer.com/article/10.1186/s40035-024-00401-4
  26. Jul 2023
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessment of Aggregated and Exosome-Associated α-Synuclein in Brain Tissue and Cerebrospinal Fluid Using Specific Immunoassays
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    ncbi.nlm.nih.gov/pmc/articles/PMC10340737/
  28. Sep 2022
  29. link.springer.com link.springer.com
    Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo
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    link.springer.com/article/10.1007/s00401-022-02491-8
  30. Mar 2022
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    l-3,4-dihydroxyphenylalanine (l-DOPA) modulates brain iron, dopaminergic neurodegeneration and motor dysfunction in iron overload and mutant alpha-synuclein mouse models of Parkinson's disease
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14676
  32. Aug 2021
  33. www.jneurosci.org www.jneurosci.org
    Untitled document
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    jneurosci.org/content/35/14/5724
  34. Jul 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC6705667/
  36. www.jneurosci.org www.jneurosci.org
    Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease
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    jneurosci.org/content/37/1/47
  37. Jan 2020
  38. www.sciencedirect.com www.sciencedirect.com
    Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult
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    sciencedirect.com/science/article/pii/S0896627319310463
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Alpha synuclein deficiency increases CD4+ T‐cells pro‐inflammatory profile in a Nurr1‐dependent manner
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14871
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14676
  41. Nov 2017
  42. www.jneurosci.org www.jneurosci.org
    Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease
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    jneurosci.org/content/37/1/47
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-Synuclein-Independent Histopathological and Motor Deficits in Mice Lacking the Endolysosomal Parkinsonism Protein Atp13a2
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    ncbi.nlm.nih.gov/pmc/articles/PMC4388928/
  44. Dec 2015
  45. www.jneurosci.org www.jneurosci.org
    Untitled document
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    1. judell 21 Dec 2015
      IMSR_JAX:004479

      Database: IMSR

      Species: Mouse

      Name: B6;C3-Tg(Prnp-SNCA*A53T)83Vle/J

      Background: None

      Affected Gene: Prnp

      Genomic Alteration: Tg(Prnp-SNCA*A53T)83Vle

      Phenotype: None

      Notes: gene symbol note: prion protein mutant stock transgene insertion 83, Virginia M-Y Lee

      Reference:

      Availability: live mouse

      Catalog ID: JAX:004479

      Proper Citation: RRID:IMSR_JAX:004479

      resolver lookup

      RRID:IMSR_JAX:004479
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    jneurosci.org/content/35/14/5724.long
  46. www.jneurosci.org www.jneurosci.org
    Untitled document
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    1. judell 17 Dec 2015
      IMSR_JAX:004479

      Database: IMSR

      Species: Mouse

      Name: B6;C3-Tg(Prnp-SNCA*A53T)83Vle/J

      Background: None

      Affected Gene: Prnp

      Genomic Alteration: Tg(Prnp-SNCA*A53T)83Vle

      Phenotype: None

      Notes: gene symbol note: prion protein mutant stock transgene insertion 83, Virginia M-Y Lee

      Reference:

      Availability: live mouse

      Catalog ID: JAX:004479

      Proper Citation: RRID:IMSR_JAX:004479

      resolver lookup

      RRID:IMSR_JAX:004479
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    jneurosci.org/content/35/14/5724.full