Hypothesis

73 Matching Annotations

Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Intestinal Neutral Ceramidase Deficiency Triggers Regulatory T Cell Response via Gd3 to Protect the Host from Intestinal Inflammation

1
1. scibot 30 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1002/advs.202512681
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12849859/
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Wnt/β-catenin-P2-HNF4α feedback loop facilitates colorectal tumorigenesis and malignancy

1
1. scibot 20 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1186/s12967-025-07133-7
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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pmc.ncbi.nlm.nih.gov/articles/PMC12625555/
Oct 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1038/s41467-025-65180-6
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12537870/
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication

1
1. scibot 19 Sep 2025
  
  in Public
  
  JAX 004586
  
  DOI: 10.1016/j.chom.2025.08.011
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

sciencedirect.com/science/article/pii/S1931312825003373
link.springer.com link.springer.com

Differential expression of villin and advillin by neuroendocrine and tuft cells in the murine lower airways

1
1. scibot 06 Sep 2025
  
  in Public
  
  JAX: 004586
  
  DOI: 10.1007/s00441-025-04003-y
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

link.springer.com/article/10.1007/s00441-025-04003-y
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Unfolded protein response transcription factor XBP1 suppresses necroptosis-induced colitis by reinforcing the mucus barrier

1
1. scibot 27 Aug 2025
  
  in Public
  
  JAX# 004586
  
  DOI: 10.1016/j.immuni.2025.07.023
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

sciencedirect.com/science/article/pii/S1074761325003322
www.cell.com www.cell.com

HNF1A and A1CF coordinate a beta cell transcription-splicing axis that is disrupted in type 2 diabetes

1
1. scibot 13 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.cmet.2025.07.007
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

cell.com/cell-metabolism/abstract/S1550-4131(25)00334-1
Jul 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225014440-main-html.html

1
1. scibot 24 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:00
  
  DOI: 10.1016/j.isci.2025.113183
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Unresolved
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RRIDCUR:Unresolved

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scibot

URL

52.53.155.43/d0106ead5bb884ca4d13dcd7bae2505050d152dc/1-s2.0-S2589004225014440-main-html.html
Jun 2025
www.nature.com www.nature.com

Environmental stress drives clearance of a persistent enteric virus in mice

1
1. scibot 28 Jun 2025
  
  in Public
  
  #004586
  
  DOI: 10.1038/s41564-025-02046-z
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

nature.com/articles/s41564-025-02046-z
Apr 2025
www.sciencedirect.com www.sciencedirect.com

A type 1 immune-stromal cell network mediates disease tolerance against intestinal infection

1
1. scibot 24 Apr 2025
  
  in Public
  
  Jackson Laboratories Cat_004586
  
  DOI: 10.1016/j.cell.2025.03.043
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Unresolved
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RRID:IMSR_JAX:004586

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425003952
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

MUC17 is an essential small intestinal glycocalyx component that is disrupted in Crohn’s disease

1
1. scibot 02 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1172/jci.insight.181481
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11948581/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Inhibition of histone methyltransferase EZH2 for immune interception of colorectal cancer in Lynch syndrome

1
1. scibot 02 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1172/jci.insight.177545
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11949072/
Mar 2025
www.sciencedirect.com www.sciencedirect.com

Therapeutic activation of IL-22-producing innate lymphoid cells enhances host defenses to Clostridioides difficile infection

1
1. scibot 29 Mar 2025
  
  in Public
  
  Jackson Laboratory004586
  
  DOI: 10.1016/j.celrep.2025.115438
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

sciencedirect.com/science/article/pii/S2211124725002098
Feb 2025
www.sciencedirect.com www.sciencedirect.com

Homeostatic antiviral protection of the neonatal gut epithelium by interferon lambda

1
1. scibot 04 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.celrep.2025.115243
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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scibot

URL

sciencedirect.com/science/article/pii/S2211124725000142
Jan 2025
52.53.155.43 52.53.155.43

1-s2.0-S258900422500166X-main-html.html

1
1. scibot 30 Jan 2025
  
  in Public
  
  JAX:004586
  
  DOI: 10.1016/j.isci.2025.111906
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

52.53.155.43/4ecee90ec62055f0d5237126b3968a346f27ed96/1-s2.0-S258900422500166X-main-html.html
www.nature.com www.nature.com

Intestinal TM6SF2 protects against metabolic dysfunction-associated steatohepatitis through the gut–liver axis

1
1. scibot 24 Jan 2025
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1038/s42255-024-01177-7
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

nature.com/articles/s42255-024-01177-7
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Type III interferons induce pyroptosis in gut epithelial cells and impair mucosal repair

1
1. scibot 16 Nov 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.cell.2024.10.010
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424011589
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Microbiota regulates neonatal disease tolerance to virus-evoked necrotizing enterocolitis by shaping the STAT1-NLRC5 axis in the intestinal epithelium

1
1. scibot 25 Sep 2024
  
  in Public
  
  strain# 004586
  
  DOI: 10.1016/j.chom.2024.08.013
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1931312824003202
www.sciencedirect.com www.sciencedirect.com

Dietary fiber promotes antigen presentation on intestinal epithelial cells and development of small intestinal CD4+CD8αα+ intraepithelial T cells

1
1. scibot 10 Sep 2024
  
  in Public
  
  004586
  
  DOI: 10.1016/j.mucimm.2024.08.010
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1933021924000928
www.sciencedirect.com www.sciencedirect.com

Paneth cell TNF signaling induces gut bacterial translocation and sepsis

1
1. scibot 10 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.chom.2024.08.007
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1931312824003147
Jun 2024
www.mdpi.com www.mdpi.com

Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.3390/cancers16112040
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

mdpi.com/2072-6694/16/11/2040
May 2024
www.sciencedirect.com www.sciencedirect.com

Epithelial aPKC deficiency leads to stem cell loss preceding metaplasia in colorectal cancer initiation

1
1. scibot 30 May 2024
  
  in Public
  
  004586
  
  DOI: 10.1016/j.devcel.2024.05.001
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  DOI:10.1016/j.devcel.2024.05.001 RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

DOI:10.1016/j.devcel.2024.05.001

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724002995
www.sciencedirect.com www.sciencedirect.com

Enterococcus-derived tyramine hijacks α2A-adrenergic receptor in intestinal stem cells to exacerbate colitis

1
1. scibot 24 May 2024
  
  in Public
  
  004586
  
  DOI: 10.1016/j.chom.2024.04.020
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1931312824001409
www.sciencedirect.com www.sciencedirect.com

HuR promotes triglyceride synthesis and intestinal fat absorption

1
1. scibot 16 May 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.celrep.2024.114238
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724005667
www.sciencedirect.com www.sciencedirect.com

IL-22 promotes mucin-type O-glycosylation and MATH1+ cell-mediated amelioration of intestinal inflammation

1
1. scibot 14 May 2024
  
  in Public
  
  004586
  
  DOI: 10.1016/j.celrep.2024.114206
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724005345
www.sciencedirect.com www.sciencedirect.com

Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance

1
1. scibot 14 May 2024
  
  in Public
  
  004586
  
  DOI: 10.1016/j.immuni.2024.03.023
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324001444
Feb 2024
www.biorxiv.org www.biorxiv.org

Single-cell profiling reveals the impact of genetic alterations on the differentiation of inflammation-induced colon tumors

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1101/2023.11.30.569463
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

biorxiv.org/content/10.1101/2023.11.30.569463v1
www.sciencedirect.com www.sciencedirect.com

Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity

1
1. scibot 07 Feb 2024
  
  in Public
  
  Jax: 004586
  
  DOI: 10.1016/j.immuni.2024.01.002
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S107476132400027X
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Gut mucosal cells transfer α-synuclein to the vagus nerve

1
1. scibot 20 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1172/jci.insight.172192
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10795834/
www.sciencedirect.com www.sciencedirect.com

Sympathetic nerve-enteroendocrine L cell communication modulates GLP-1 release, brain glucose utilization, and cognitive function

1
1. scibot 19 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.neuron.2023.12.012
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S0896627323009716
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intestinal SURF4 is essential for apolipoprotein transport and lipoprotein secretion

1
1. scibot 05 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.molmet.2023.101847
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10755498/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Age-associated features of norovirus infection analysed in mice

1
1. scibot 03 Jan 2024
  
  in Public
  
  004586
  
  DOI: 10.1038/s41564-023-01383-1
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10484054/
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Dietary environmental factors shape the immune defense against Cryptosporidium infection

1
1. scibot 20 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.chom.2023.11.008
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1931312823004584
Nov 2023
www.sciencedirect.com www.sciencedirect.com

TGFB1 induces fetal reprogramming and enhances intestinal regeneration

1
1. scibot 10 Nov 2023
  
  in Public
  
  JAX:004586
  
  DOI: 10.1016/j.stem.2023.09.015
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1934590923003624
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Novel tumor organoid-based mouse model to study image-guided radiation therapy of rectal cancer after non-invasive and precise endoscopic implantation

1
1. scibot 27 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.ijrobp.2023.10.008
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S0360301623080148
www.sciencedirect.com www.sciencedirect.com

An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism

1
1. scibot 14 Oct 2023
  
  in Public
  
  JAX:004586
  
  DOI: 10.1016/j.chom.2023.09.002
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1931312823003694
journals.asm.org journals.asm.org

Akkermansia muciniphila supplementation improves glucose tolerance in intestinal Ffar4 knockout mice during the daily light to dark transition

1
1. scibot 13 Oct 2023
  
  in Public
  
  JAX:004586
  
  DOI: 10.1128/msystems.00573-23
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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journals.asm.org/doi/10.1128/msystems.00573-23
Sep 2023
www.nature.com www.nature.com

Blockade of interferon signaling decreases gut barrier integrity and promotes severe West Nile virus disease

1
1. scibot 29 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:00458684
  
  DOI: 10.1038/s41467-023-41600-3
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @anisehay
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Unresolved
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nature.com/articles/s41467-023-41600-3
Aug 2023
www.biorxiv.org www.biorxiv.org

Gut mucosal cells transfer α-synuclein to the vagus nerve

1
1. scibot 29 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1101/2023.08.14.553305
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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biorxiv.org/content/10.1101/2023.08.14.553305v1
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

1
1. scibot 16 Mar 2023
  
  in Public
  
  JAX:004
  
  DOI: 10.1016/j.immuni.2023.02.018
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @sofiakhan13
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1074761323000924
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

1
1. scibot 10 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.cell.2022.11.029
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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sciencedirect.com/science/article/pii/S0092867422015045
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity

1
1. scibot 10 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.celrep.2022.111593
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124722014589
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Adenosine metabolized from extracellular ATP promotes type 2 immunity through triggering A2BAR signaling in intestinal epithelial cells

1
1. scibot 06 Aug 2022
  
  in Public
  
  Jax Strain #004586
  
  DOI: 10.1016/j.celrep.2022.111150
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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sciencedirect.com/science/article/pii/S2211124722009597
May 2022
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Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway

1
1. scibot 19 May 2022
  
  in Public
  
  JAX:004586
  
  DOI: 10.1016/j.ebiom.2022.104060
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S2352396422002419
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Optogenetic inhibition of colon epithelium reduces hypersensitivity in a mouse model of inflammatory bowel disease

1
1. scibot 02 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1097/j.pain.0000000000002110
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7969374/
Jan 2022
www.sciencedirect.com www.sciencedirect.com

IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

1
1. scibot 27 Jan 2022
  
  in Public
  
  Cat#: 004586
  
  DOI: 10.1016/j.immuni.2021.12.016
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1074761321005525
www.sciencedirect.com www.sciencedirect.com

Enterocyte superoxide dismutase 2 deletion drives obesity

1
1. scibot 11 Jan 2022
  
  in Public
  
  Cat# 004586
  
  DOI: 10.1016/j.isci.2021.103707
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S2589004221016771
www.sciencedirect.com www.sciencedirect.com

Intestinal Gpr17 deficiency improves glucose metabolism by promoting GLP-1 secretion

1
1. scibot 05 Jan 2022
  
  in Public
  
  CAT#004586
  
  DOI: 10.1016/j.celrep.2021.110179
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S221112472101679X
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

1
1. scibot 03 Nov 2021
  
  in Public
  
  Cat#004586
  
  DOI: 10.1016/j.celrep.2021.109916
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S2211124721013899
Oct 2021
journals.physiology.org journals.physiology.org

Optogenetic activation of the distal colon epithelium engages enteric nervous system circuits to initiate motility patterns | American Journal of Physiology-Gastrointestinal and Liver Physiology

1
1. scibot 18 Oct 2021
  
  in Public
  
  RRID: IMSR_JAX004586
  
  DOI: 10.1152/ajpgi.00026.2021
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:004586
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journals.physiology.org/doi/full/10.1152/ajpgi.00026.2021
Sep 2021
www.sciencedirect.com www.sciencedirect.com

PKCλ/ι inhibition activates an ULK2-mediated interferon response to repress tumorigenesis

1
1. scibot 24 Sep 2021
  
  in Public
  
  Stock No: 004586
  
  DOI: 10.1016/j.molcel.2021.08.039
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1097276521007292
Jul 2021
www.sciencedirect.com www.sciencedirect.com

The microbiota coordinates diurnal rhythms in innate immunity with the circadian clock

1
1. scibot 31 Jul 2021
  
  in Public
  
  Stock No. 004586
  
  DOI: 10.1016/j.cell.2021.07.001
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421008278
www.sciencedirect.com www.sciencedirect.com

T Helper Cell Cytokines Modulate Intestinal Stem Cell Renewal and Differentiation

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.cell.2018.10.008
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Validated RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S0092867418313163
www.sciencedirect.com www.sciencedirect.com

MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson Laboratory004586
  
  DOI: 10.1016/j.immuni.2019.08.011
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1074761319303620
www.sciencedirect.com www.sciencedirect.com

Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryStock 004586
  
  DOI: 10.1016/j.immuni.2019.05.021
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Unrecognized
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sciencedirect.com/science/article/pii/S1074761319302419
www.jneurosci.org www.jneurosci.org

Optogenetic Activation of Colon Epithelium of the Mouse Produces High-Frequency Bursting in Extrinsic Colon Afferents and Engages Visceromotor Responses

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX004586
  
  DOI: 10.1523/JNEUROSCI.0837-18.2018
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Unrecognized RRIDCUR:SyntaxError RRID:IMSR_JAX:004586
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jneurosci.org/content/38/25/5788
www.sciencedirect.com www.sciencedirect.com

Circulating Levels of Soluble Dipeptidyl Peptidase-4 Are Dissociated from Inflammation and Induced by Enzymatic DPP4 Inhibition

1
1. scibot 27 Jul 2021
  
  in Public
  
  004586
  
  DOI: 10.1016/j.cmet.2018.10.001
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRIDCUR:Missing RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1550413118306338
May 2021
www.sciencedirect.com www.sciencedirect.com

Western diet induces Paneth cell defects through microbiome alterations and farnesoid X receptor and type I interferon activation

1
1. scibot 19 May 2021
  
  in Public
  
  Cat. # 004586
  
  DOI: 10.1016/j.chom.2021.04.004
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1931312821001803
www.sciencedirect.com www.sciencedirect.com

Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.stem.2020.07.003
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1934590920303416
www.sciencedirect.com www.sciencedirect.com

mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways

1
1. scibot 05 May 2021
  
  in Public
  
  JAX:004586
  
  DOI: 10.1016/j.celrep.2021.109069
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S2211124721004009
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Mitochondria Define Intestinal Stem Cell Differentiation Downstream of a FOXO/Notch Axis

1
1. scibot 29 Apr 2021
  
  in Public
  
  JAX#004586
  
  DOI: 10.1016/j.cmet.2020.10.005
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1550413120305386
www.sciencedirect.com www.sciencedirect.com

Deletion of Fructokinase in the Liver or in the Intestine Reveals Differential Effects on Sugar-Induced Metabolic Dysfunction

1
1. scibot 29 Apr 2021
  
  in Public
  
  004586
  
  DOI: 10.1016/j.cmet.2020.05.012
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1550413120302515
www.sciencedirect.com www.sciencedirect.com

Inflation-collapse dynamics drive patterning and morphogenesis in intestinal organoids

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.stem.2021.04.002
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586
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sciencedirect.com/science/article/pii/S1934590921001594
www.sciencedirect.com www.sciencedirect.com

Enteric helminth coinfection enhances host susceptibility to neurotropic flaviviruses via a tuft cell-IL-4 receptor signaling axis

1
1. scibot 27 Apr 2021
  
  in Public
  
  Cat # 004586
  
  DOI: 10.1016/j.cell.2021.01.051
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867421000945
www.sciencedirect.com www.sciencedirect.com

Hierarchical cell-type-specific functions of caspase-11 in LPS shock and antibacterial host defense

1
1. scibot 21 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.celrep.2021.109012
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
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  RRID:IMSR_JAX:004586 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124721003260
Feb 2021
physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com

Tissue‐specific deletion of mouse basolateral uniporter LAT4 (Slc43a2) reveals its crucial role in small intestine and kidney amino acid transport

1
1. scibot 27 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1113/JP280234
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  What is this?
  
  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

physoc.onlinelibrary.wiley.com/doi/10.1113/JP280234
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Nod1 promotes colorectal carcinogenesis by regulating the immunosuppressive functions of tumor-infiltrating myeloid cells

1
1. scibot 28 Jan 2021
  
  in Public
  
  Cat# 004586
  
  DOI: 10.1016/j.celrep.2020.108677
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  What is this?
  
  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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RRID:IMSR_JAX:004586

RRIDCUR:Missing

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scibot

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sciencedirect.com/science/article/pii/S2211124720316661
www.sciencedirect.com www.sciencedirect.com

Magnesium and Calcium Homeostasis Depend on KCTD1 Function in the Distal Nephron

1
1. scibot 22 Jan 2021
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.celrep.2020.108616
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

RRIDCUR:Validated

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scibot

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sciencedirect.com/science/article/pii/S2211124720316053
Sep 2020
www.sciencedirect.com www.sciencedirect.com

FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX# 004586
  
  DOI: 10.1016/j.immuni.2020.04.002
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  What is this?
  
  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

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sciencedirect.com/science/article/pii/S1074761320301606
www.sciencedirect.com www.sciencedirect.com

Protein O-GlcNAc Modification Links Dietary and Gut Microbial Cues to the Differentiation of Enteroendocrine L Cells

1
1. scibot 03 Sep 2020
  
  in Public
  
  Villin-Cre
  
  DOI: 10.1016/j.celrep.2020.108013
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  Curator comments: B6.Cg-Tg(Vil1-cre)997Gum/J Mus musculus IMSR Cat# JAX:004586
  
  What is this?
  
  RRID:IMSR_JAX:004586 RRIDCUR:Missing
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RRID:IMSR_JAX:004586

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124720309980
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  DOI: 10.1016/j.cmet.2019.08.009
  
  Resource: (IMSR Cat# JAX_004586,RRID:IMSR_JAX:004586)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  What is this?
  
  RRID:IMSR_JAX:004586 RRIDCUR:Validated
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RRID:IMSR_JAX:004586

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1550413119304383
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:004586
  
  Resource used:
  
  RRID:IMSR_JAX:004586
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S1931312818300428
www.sciencedirect.com www.sciencedirect.com

Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:004586
  
  Resource used:
  
  RRID:IMSR_JAX:004586
  
  SciCrunch record: RRID:IMSR_JAX:004586
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:004586
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RRID:IMSR_JAX:004586

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scibot

URL

sciencedirect.com/science/article/pii/S153561081730507X

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