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  1. Last 7 days
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    Serotonin modulates lineage plasticity in neuroendocrine prostate cancer via epigenetic reprogramming
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    pmc.ncbi.nlm.nih.gov/articles/PMC13040212/
  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coordinated stimulation of axon regenerative and neurodegenerative transcriptional programs by ATF4 following optic nerve injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC12945389/
  5. Dec 2025
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    Immunocompetent murine models recapitulate the heterogeneous tumor immune microenvironment of human liposarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664306/
  7. Nov 2025
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    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12569591/
  9. Oct 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Non-cell-autonomous tumor promotion in DICER1 cancer predisposition
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    sciencedirect.com/science/article/pii/S1534580725005398
  11. Sep 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing neural stem cell integration in the injured spinal cord through targeted PTEN modulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12407558/
  13. Jul 2025
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synergistic Inhibition of Prostate Cancer Progression in Mice With a Combination of Curcumin and Ursolic Acid in the Diet
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    onlinelibrary.wiley.com/doi/full/10.1002/mc.70000
  15. Jun 2025
  16. elifesciences.org elifesciences.org
    Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
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    elifesciences.org/articles/100604
  17. Apr 2025
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    sciencedirect.com/science/article/pii/S153561082500128X
  19. Mar 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pten Loss Triggers Progressive Photoreceptor Degeneration in an mTORC1-Independent Manner
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    pmc.ncbi.nlm.nih.gov/articles/PMC11935561/
  21. Nov 2024
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Somatostatin interneuron fate-mapping and structure in a Pten knockout model of epilepsy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532043/
  23. Aug 2024
  24. www.biorxiv.org www.biorxiv.org
    Local glycolysis supports injury-induced axonal regeneration
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    biorxiv.org/content/10.1101/2024.01.29.577706v1
  25. www.cell.com www.cell.com
    Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior
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    cell.com/cell-reports/fulltext/S2211-1247(21)00614-8
  26. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Conditional Pten knockout in parvalbumin- or somatostatin-positive neurons sufficiently leads to autism-related behavioral phenotypes
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    molecularbrain.biomedcentral.com/article/10.1186/s13041-021-00731-8
  27. Jul 2024
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    PTEN acts as a crucial inflammatory checkpoint controlling TLR9/IL-6 axis in B cells
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    sciencedirect.com/science/article/pii/S2589004224016134
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    Glycolytic flux controls retinal progenitor cell differentiation via regulating Wnt signaling
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    biorxiv.org/content/10.1101/2024.07.12.603298v1
  30. www.cell.com www.cell.com
    Elevating PLK1 overcomes BETi resistance in prostate cancer via triggering BRD4 phosphorylation-dependent degradation in mitosis
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    cell.com/cell-reports/fulltext/S2211-1247(24)00760-5
  31. May 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Critical roles of the miR-17∼92 family in thymocyte development, leukemogenesis, and autoimmunity
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    sciencedirect.com/science/article/pii/S2211124724005898
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    Parvalbumin interneuron activity in autism underlies susceptibility to PTSD-like memory formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089364/
  34. Apr 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  36. Mar 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Pten regulates endocytic trafficking of cell adhesion and Wnt signaling molecules to pattern the retina
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    sciencedirect.com/science/article/pii/S2211124724003334
  38. Jan 2024
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    Distinct mesenchymal cell states mediate prostate cancer progression
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    link.springer.com/article/10.1038/s41467-023-44210-1
  40. Dec 2023
  41. www.sciencedirect.com www.sciencedirect.com
    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
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    sciencedirect.com/science/article/pii/S2211124723015309
  42. Mar 2023
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurovascular development in Pten and Tsc2 mouse mutants
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    ncbi.nlm.nih.gov/pmc/articles/PMC9953070/
  44. Nov 2022
  45. www.sciencedirect.com www.sciencedirect.com
    Targeting PTEN but not SOCS3 resists an age-dependent decline in promoting axon sprouting
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    sciencedirect.com/science/article/pii/S2589004222016558
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    Disruption of mTORC1 rescues neuronal overgrowth and synapse function dysregulated by Pten loss
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    sciencedirect.com/science/article/pii/S2211124722014358
  47. Aug 2022
  48. www.sciencedirect.com www.sciencedirect.com
    Single-cell transcriptome analysis of regenerating RGCs reveals potent glaucoma neural repair genes
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    sciencedirect.com/science/article/pii/S0896627322006018
  49. Jul 2022
  50. www.sciencedirect.com www.sciencedirect.com
    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
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    sciencedirect.com/science/article/pii/S2211124722009317
  51. Jun 2022
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    Overlapping transcriptional programs promote survival and axonal regeneration of injured retinal ganglion cells
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    sciencedirect.com/science/article/pii/S0896627322005402
  53. www.sciencedirect.com www.sciencedirect.com
    Muscle satellite cells are impaired in type 2 diabetic mice by elevated extracellular adenosine
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    sciencedirect.com/science/article/pii/S2211124722006593
  54. May 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Macrophage-derived cholesterol contributes to therapeutic resistance in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8563406/
  56. Jan 2022
  57. www.eneuro.org www.eneuro.org
    An ATF3-CreERT2 Knock-In Mouse for Axotomy-Induced Genetic Editing: Proof of Principle
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    eneuro.org/content/6/2/ENEURO.0025-19.2019
  58. Nov 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Protein kinase Cι and SRC signaling define reciprocally related subgroups of glioblastoma with distinct therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2211124721015400
  60. Aug 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    ncbi.nlm.nih.gov/pmc/articles/PMC6464513/
  62. Jul 2021
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6258034/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC5839742/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytokeratin 19 promoter directs the expression of Cre recombinase in various epithelia of transgenic mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC5392329/
  66. www.sciencedirect.com www.sciencedirect.com
    Impact of mTOR hyperactive neurons on the morphology and physiology of adjacent neurons: Do PTEN KO cells make bad neighbors?
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    sciencedirect.com/science/article/pii/S0014488619301785
  67. Jun 2021
  68. www.cell.com www.cell.com
    Transient developmental imbalance of cortical interneuron subtypes presages long-term changes in behavior
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    cell.com/cell-reports/fulltext/S2211-1247(21)00614-8
  69. May 2021
  70. www.sciencedirect.com www.sciencedirect.com
    mTOR-driven neural circuit changes initiate an epileptogenic cascade
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    sciencedirect.com/science/article/pii/S030100822030229X
  71. Sep 2020
  72. www.sciencedirect.com www.sciencedirect.com
    PI3K isoform-selective inhibition in neuron-specific PTEN-deficient mice rescues molecular defects and reduces epilepsy-associated phenotypes
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    sciencedirect.com/science/article/pii/S0969996120303016
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PTEN suppresses epithelial–mesenchymal transition and cancer stem cell activity by downregulating Abi1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7391766/
  74. Jan 2020
  75. www.sciencedirect.com www.sciencedirect.com
    Thrombospondin-1 Mediates Axon Regeneration in Retinal Ganglion Cells
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    sciencedirect.com/science/article/pii/S0896627319304970
  76. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent dendritic elaboration requires Pten
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    sciencedirect.com/science/article/pii/S096999611930378X
  77. Nov 2018
  78. www.sciencedirect.com www.sciencedirect.com
    The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment
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    sciencedirect.com/science/article/pii/S1074761318304357
  79. www.sciencedirect.com www.sciencedirect.com
    Self-reinforcing effects of mTOR hyperactive neurons on dendritic growth
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    sciencedirect.com/science/article/pii/S0014488618305259
  80. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S2211124718314979
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    EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation
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    sciencedirect.com/science/article/pii/S1535610818302290
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    Myelination of Neuronal Cell Bodies when Myelin Supply Exceeds Axonal Demand
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    sciencedirect.com/science/article/pii/S0960982218302549
  83. Nov 2017
  84. www.sciencedirect.com www.sciencedirect.com
    PTEN deletion increases hippocampal granule cell excitability in male and female mice
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    sciencedirect.com/science/article/pii/S0969996117302048