Hypothesis

33 Matching Annotations

Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Control of Inflammatory Response by Tissue Microenvironment

2
1. scibot 24 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1101/2024.05.10.592432
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRID:IMSR_JAX:007561
2. scibot 24 Sep 2025
  
  in Public
  
  Jackson Laboratory Cat_007561
  
  DOI: 10.1101/2024.05.10.592432
  
  Resource: None
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:007561
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RRIDCUR:Unresolved

RRID:IMSR_JAX:007561

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11118380/
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

HIF1α mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise

1
1. scibot 25 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1073/pnas.2504080122
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12280960/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Hepatic BMAL1 and HIF1α regulate a time-dependent hypoxic response and prevent hepatopulmonary-like syndrome

1
1. scibot 13 Aug 2024
  
  in Public
  
  Jackson Laboratories007561
  
  DOI: 10.1016/j.cmet.2024.07.003
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

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sciencedirect.com/science/article/pii/S1550413124002742
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Vhl safeguards thymic epithelial cell identity and thymopoietic capacity by constraining Hif1a activity during development

1
1. scibot 26 Jul 2024
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.isci.2024.110258
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC11261450/
May 2024
www.sciencedirect.com www.sciencedirect.com

Metabolic coordination between skin epithelium and type 17 immunity sustains chronic skin inflammation

1
1. scibot 21 May 2024
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.immuni.2024.04.022
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324002279
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Transcription factor Tox2 is required for metabolic adaptation and tissue residency of ILC3 in the gut

1
1. scibot 30 Apr 2024
  
  in Public
  
  Jackson LaboratoryStrain# 007561
  
  DOI: 10.1016/j.immuni.2024.04.001
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324002061
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Granulocytic myeloid-derived suppressor cell activity during biofilm infection is regulated by a glycolysis-HIF1a axis

1
1. scibot 18 Apr 2024
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1172/JCI174051
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11014666/
Mar 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury

1
1. scibot 16 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.21203/rs.3.rs-3938716/v1
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Augmentation of scleral glycolysis promotes myopia through histone lactylation

1
1. scibot 19 Jan 2024
  
  in Public
  
  Jackson LaboratoryStock No: 007561
  
  DOI: 10.1016/j.cmet.2023.12.023
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1550413123004746
Dec 2023
www.sciencedirect.com www.sciencedirect.com

IL-18-induced HIF-1α in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

1
1. scibot 02 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.celrep.2023.113508
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723015206
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Lactate produced by alveolar type II cells suppresses inflammatory alveolar macrophages in acute lung injury

1
1. scibot 01 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1096/fj.202301722R
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202301722R
Oct 2023
www.sciencedirect.com www.sciencedirect.com

Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.xcrm.2023.101236
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S2666379123004135
Apr 2023
www.sciencedirect.com www.sciencedirect.com

A tissue injury sensing and repair pathway distinct from host pathogen defense

1
1. scibot 26 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.cell.2023.03.031
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S0092867423003288
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Lipid-laden lung mesenchymal cells foster breast cancer metastasis via metabolic reprogramming of tumor cells and natural killer cells

1
1. scibot 08 Dec 2022
  
  in Public
  
  JAX:007561
  
  DOI: 10.1016/j.cmet.2022.11.003
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1550413122004946
Apr 2022
www.sciencedirect.com www.sciencedirect.com

Stromal HIF2 Regulates Immune Suppression in the Pancreatic Cancer Microenvironment

1
1. scibot 08 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1053/j.gastro.2022.02.024
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S0016508522001548
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

1
1. scibot 09 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.7554/eLife.70555
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8896828/
Dec 2021
www.sciencedirect.com www.sciencedirect.com

Coenzyme A fuels T cell anti-tumor immunity

1
1. scibot 08 Dec 2021
  
  in Public
  
  Stock#007561
  
  DOI: 10.1016/j.cmet.2021.11.010
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRID:IMSR_JAX:007561 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121005386
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction

1
1. scibot 11 Nov 2021
  
  in Public
  
  Stock No: 007561
  
  DOI: 10.1016/j.stem.2021.10.009
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:007561
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RRIDCUR:Missing

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1934590921004215
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
  in Public
  
  Stock#007561
  
  DOI: 10.1016/j.cmet.2021.09.002
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:007561
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RRIDCUR:Missing

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121004216
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HIF1α is required for NK cell metabolic adaptation during virus infection

1
1. scibot 27 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.7554/eLife.68484
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8382296/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 13 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.celrep.2019.03.029
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6461402/
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 31 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.immuni.2019.01.021
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1074761319300445
Jun 2021
www.sciencedirect.com www.sciencedirect.com

MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages

1
1. scibot 16 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.celrep.2021.109264
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721006318
May 2021
www.sciencedirect.com www.sciencedirect.com

Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

1
1. scibot 06 May 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.immuni.2020.05.001
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320301825
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy

1
1. scibot 24 Apr 2021
  
  in Public
  
  JAX:007561
  
  DOI: 10.1016/j.cell.2020.06.014
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420307455
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis

1
1. scibot 21 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:007
  
  DOI: 10.1038/s41598-021-85357-5
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:IMSR_JAX:007561
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RRIDCUR:SyntaxError

RRID:IMSR_JAX:007561

RRIDCUR:Unresolved

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7966401/
Jan 2021
www.jneurosci.org www.jneurosci.org

HIFα regulates developmental myelination independent of autocrine Wnt signaling

1
1. scibot 29 Jan 2021
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1523/JNEUROSCI.0731-20.2020
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

jneurosci.org/content/41/2/251
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bmal1 integrates mitochondrial metabolism and macrophage activation

1
1. scibot 05 Sep 2020
  
  in Public
  
  JAX:007561
  
  DOI: 10.7554/eLife.54090
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRIDCUR:Validated RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7259948/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glial type specific regulation of CNS angiogenesis by HIFα-activated different signaling pathways

1
1. scibot 03 Sep 2020
  
  in Public
  
  RRID: IMSR_JAX:007561
  
  DOI: 10.1038/s41467-020-15656-4
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
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  RRID:IMSR_JAX:007561
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RRID:IMSR_JAX:007561

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7181614/
www.sciencedirect.com www.sciencedirect.com

Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar Regeneration

1
1. scibot 03 Sep 2020
  
  in Public
  
  Hi1faflox/flox
  
  DOI: 10.1016/j.stem.2020.06.020
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  Curator comments: B6.129-Hif1atm3Rsjo/J Mus musculus IMSR Cat# JAX:007561
  
  What is this?
  
  RRID:IMSR_JAX:007561 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1934590920302873
Jan 2020
www.sciencedirect.com www.sciencedirect.com

A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFα-Mediated Recruitment of Neutrophils

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:007561
  
  DOI: 10.1016/j.immuni.2019.03.001
  
  Resource: (IMSR Cat# JAX_007561,RRID:IMSR_JAX:007561)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  What is this?
  
  RRID:IMSR_JAX:007561 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1074761319300913
Nov 2018
www.sciencedirect.com www.sciencedirect.com

PINK1 and PARK2 Suppress Pancreatic Tumorigenesis through Control of Mitochondrial Iron-Mediated Immunometabolism

1
1. scibot 05 Nov 2018
  
  in Public
  
  007561
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:007561
  
  SciCrunch record: RRID:IMSR_JAX:007561
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:007561 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:007561

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scibot

URL

sciencedirect.com/science/article/pii/S1534580718305975