Hypothesis

85 Matching Annotations

Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

IL-2/IL-15 signaling induces NK cell production of FLT3LG augmenting anti-PD-1 immunotherapy

1
1. scibot 06 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1158/2326-6066.CIR-24-1259
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12582536/
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Quercetin-derived microbial metabolite DOPAC potentiates CD8+ T cell anti-tumor immunity via NRF2-mediated mitophagy

1
1. scibot 28 Oct 2025
  
  in Public
  
  Strain NO.008449
  
  DOI: 10.1016/j.cmet.2025.09.010
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S155041312500395X
Sep 2025
www.sciencedirect.com www.sciencedirect.com

E. coli-activated cellular circuit restrains intestinal inflammatory microbiota-specific T cells and protects against colitis

1
1. scibot 24 Sep 2025
  
  in Public
  
  Jackson LaboratoriesJAX # 008449
  
  DOI: 10.1016/j.celrep.2025.116332
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725011039
www.sciencedirect.com www.sciencedirect.com

Integrin CD103 expression in naive CD8+ T cells promotes cytokine-driven acquisition of memory phenotype and effector function

1
1. scibot 16 Sep 2025
  
  in Public
  
  The Jackson LaboratoryStrain #:008449
  
  DOI: 10.1016/j.immuni.2025.08.014
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325003772
www.sciencedirect.com www.sciencedirect.com

Immunometabolic defects of CD8+ T cells disrupt gut barrier integrity in people with HIV

1
1. scibot 12 Sep 2025
  
  in Public
  
  Jackson LabsStock# 008449
  
  DOI: 10.1016/j.cell.2025.08.024
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425009791
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Lymphoma accelerates T cell and tissue aging

1
1. scibot 26 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.ccell.2025.07.023
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825003290
www.biorxiv.org www.biorxiv.org

IFNG-producing self-reactive CD4+ T cells drive autoimmune adrenalitis in a mouse model of Addison’s disease

1
1. scibot 20 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1101/2025.08.11.669305
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

biorxiv.org/content/10.1101/2025.08.11.669305v2
www.sciencedirect.com www.sciencedirect.com

Stress-induced glucocorticoids enhance acute inflammation by promoting the differentiation of Th17 cells

1
1. scibot 05 Aug 2025
  
  in Public
  
  JAX:008449
  
  DOI: 10.1016/j.celrep.2025.116093
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725008642
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.cell.2025.05.016
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425005665
Jun 2025
www.sciencedirect.com www.sciencedirect.com

Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy

1
1. scibot 12 Jun 2025
  
  in Public
  
  JAX:008449
  
  DOI: 10.1016/j.immuni.2025.05.001
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1074761325001943
Apr 2025
www.sciencedirect.com www.sciencedirect.com

The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function

1
1. scibot 01 Apr 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2025.115456
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S221112472500227X
www.sciencedirect.com www.sciencedirect.com

Meningeal lymphatics-microglia axis regulates synaptic physiology

1
1. scibot 01 Apr 2025
  
  in Public
  
  RRID:ISMR_JAX:008449
  
  DOI: 10.1016/j.cell.2025.02.022
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425002107
Mar 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 14 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1101/2025.03.04.641465
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

52.53.155.43/6f9c92d712d7566716569fd5a44dd23a05e30ab6/PDF-html.html
Feb 2025
52.53.155.43 52.53.155.43

1-s2.0-S2589004225003037-main-html.html

1
1. scibot 20 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.isci.2025.112043
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

52.53.155.43/3dd3cafa6eaa243b57db8603cc2d3fd3d1e8448b/1-s2.0-S2589004225003037-main-html.html
www.sciencedirect.com www.sciencedirect.com

Platelets tune fear memory in mice

1
1. scibot 04 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2025.115261
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725000324
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Fiber- and acetate-mediated modulation of MHC-II expression on intestinal epithelium protects from Clostridioides difficile infection

1
1. scibot 23 Jan 2025
  
  in Public
  
  Jackson LaboratoriesStrain# 008449
  
  DOI: 10.1016/j.chom.2024.12.017
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1931312824004840
52.53.155.43 52.53.155.43

1-s2.0-S2589004225000707-main-html.html

1
1. scibot 23 Jan 2025
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.isci.2025.111810
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

52.53.155.43/e22ad0f8d0e449f7284596344d2cc636d4e26c8e/1-s2.0-S2589004225000707-main-html.html
www.cell.com www.cell.com

A gut commensal protozoan determines respiratory disease outcomes by shaping pulmonary immunity

1
1. scibot 05 Jan 2025
  
  in Public
  
  008449
  
  DOI: 10.1016/s0092-8674(00)91910-x
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

cell.com/cell/fulltext/S0092-8674(24)01336-9
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Cytosolic bacterial pathogens activate TLR pathways in tumors that synergistically enhance STING agonist cancer therapies

1
1. scibot 14 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.isci.2024.111385
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2589004224026105
Nov 2024
elifesciences.org elifesciences.org

Neurotrophic factor Neuritin modulates T cell electrical and metabolic state for the balance of tolerance and immunity

1
1. scibot 26 Nov 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.7554/eLife.96812
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

elifesciences.org/articles/96812
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A neutrophil–B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4

1
1. scibot 14 Nov 2024
  
  in Public
  
  008449
  
  DOI: 10.7554/eLife.78291
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC9525059/
Oct 2024
www.sciencedirect.com www.sciencedirect.com

CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny

1
1. scibot 02 Oct 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2024.114797
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724011483
Sep 2024
www.biorxiv.org www.biorxiv.org

IL-34 empowers regulatory T cells with novel non-canonical function to safeguard brain barrier integrity during neuro-inflammation

1
1. scibot 29 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1101/2024.09.09.611994
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

biorxiv.org/content/10.1101/2024.09.09.611994v1
www.pnas.org www.pnas.org

Disruption of the ZFP574–THAP12 complex suppresses B cell malignancies in mice

1
1. scibot 26 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1073/pnas.2409232121
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

pnas.org/doi/abs/10.1073/pnas.2409232121
Jul 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metabolic reprogramming and dysregulated IL-17 production impairs CD4 T cell function post sepsis

1
1. scibot 18 Jul 2024
  
  in Public
  
  The Jackson Laboratory008449
  
  DOI: 10.1016/j.isci.2024.110114
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11251092/
May 2024
www.sciencedirect.com www.sciencedirect.com

Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor

1
1. scibot 14 May 2024
  
  in Public
  
  008449
  
  DOI: 10.1016/j.cell.2024.04.023
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424004483
www.sciencedirect.com www.sciencedirect.com

Decreased GATA3 levels cause changed mouse cutaneous innate lymphoid cell fate, facilitating hair follicle recycling

1
1. scibot 09 May 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.devcel.2024.04.015
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724002685
Apr 2024
www.sciencedirect.com www.sciencedirect.com

CD80 on skin stem cells promotes local expansion of regulatory T cells upon injury to orchestrate repair within an inflammatory environment

1
1. scibot 30 Apr 2024
  
  in Public
  
  The Jackson LaboratoryCat# 008449
  
  DOI: 10.1016/j.immuni.2024.04.003
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S1074761324002085
www.sciencedirect.com www.sciencedirect.com

The microbiota and T cells non-genetically modulate inherited phenotypes transgenerationally

1
1. scibot 05 Apr 2024
  
  in Public
  
  Strain #008449
  
  DOI: 10.1016/j.celrep.2024.114029
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724003577
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Tonic TCR and IL-1β signaling mediate phenotypic alterations of naive CD4+ T cells

2
1. scibot 19 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2024.113954
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
2. scibot 19 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2024.113954
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724002821
www.sciencedirect.com www.sciencedirect.com

NR4a1/2 deletion promotes accumulation of TCF1+ stem-like precursors of exhausted CD8+ T cells in the tumor microenvironment

2
1. scibot 06 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2024.113898
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
2. scibot 06 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2024.113898
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724002262
Feb 2024
www.sciencedirect.com www.sciencedirect.com

The CD27/CD70 pathway negatively regulates visceral adipose tissue-resident Th2 cells and controls metabolic homeostasis

1
1. scibot 22 Feb 2024
  
  in Public
  
  The Jackson LaboratoryStock#:008449
  
  DOI: 10.1016/j.celrep.2024.113824
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  What is this?
  
  RRID:IMSR_JAX:008449
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RRID:IMSR_JAX:008449

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724001529
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Distinct spatiotemporal dynamics of CD8+ T cell-derived cytokines in the tumor microenvironment

1
1. scibot 13 Jan 2024
  
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  Jackson LaboratoriesStrain #:008449
  
  DOI: 10.1016/j.ccell.2023.12.010
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10783802/
Dec 2023
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Mouse gingival single-cell transcriptomic atlas identified a novel fibroblast subpopulation activated to guide oral barrier immunity in periodontitis

1
1. scibot 01 Dec 2023
  
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  JAX:008449
  
  DOI: 10.7554/eLife.88183
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10684155/
Nov 2023
www.science.org www.science.org

Resident regulatory T cells reflect the immune history of individual lymph nodes

1
1. scibot 03 Nov 2023
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1126/sciimmunol.adj5789
  
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science.org/doi/10.1126/sciimmunol.adj5789
Aug 2023
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Characterizing CD4 T cell differentiation in mouse small intestine using T cell transfer, lamina propria preparation, and flow cytometry

1
1. scibot 18 Aug 2023
  
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  JAX:008449
  
  DOI: 10.1016/j.xpro.2023.102485
  
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52.53.155.43 52.53.155.43

Homeostatic PD-1 signaling restrains EOMES-dependent oligoclonal expansion of liver-resident CD8 T cells

2
1. scibot 12 Aug 2023
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2023.112876
  
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2. scibot 10 Aug 2023
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2023.112876
  
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52.53.155.43/7d9bf3333b9425342ca4204697d643342388db9f/PIIS2211124723008872-html.html
Jun 2023
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IFNγ is a central node of cancer immune equilibrium

1
1. scibot 06 Jun 2023
  
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  RRID:IMSR_JAX:008
  
  DOI: 10.1016/j.celrep.2023.112219
  
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sciencedirect.com/science/article/pii/S2211124723002309
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Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine

1
1. scibot 01 Jun 2023
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1038/s41467-023-38899-3
  
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nature.com/articles/s41467-023-38899-3
May 2023
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Mechanisms Regulating the loss of Tregs in HUPO mice that Develop Spontaneous Inflammatory Arthritis

1
1. scibot 14 May 2023
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.isci.2023.106734
  
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sciencedirect.com/science/article/pii/S2589004223008118
Mar 2023
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Endoplasmic reticulum stress in the intestinal epithelium initiates purine metabolite synthesis and promotes Th17 cell differentiation in the gut

1
1. scibot 16 Mar 2023
  
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  JAX:008
  
  DOI: 10.1016/j.immuni.2023.02.018
  
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sciencedirect.com/science/article/pii/S1074761323000924
Feb 2023
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Circumvention of luteolysis reveals parturition pathways in mice dependent upon innate type 2 immunity

1
1. scibot 09 Feb 2023
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.immuni.2023.01.005
  
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sciencedirect.com/science/article/pii/S1074761323000158
Nov 2022
www.pnas.org www.pnas.org

Monocytes maintain central nervous system homeostasis following helminth-induced inflammation

1
1. scibot 17 Nov 2022
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1073/pnas.2201645119
  
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pnas.org/doi/abs/10.1073/pnas.2201645119
Jul 2022
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Group 3 innate lymphocytes make a distinct contribution to Type 17 immunity in bladder defence

1
1. scibot 09 Jul 2022
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.isci.2022.104660
  
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sciencedirect.com/science/article/pii/S2589004222009324
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Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization

1
1. scibot 08 Jul 2022
  
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  JAX Stock: 008449
  
  DOI: 10.1016/j.immuni.2022.05.014
  
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sciencedirect.com/science/article/pii/S1074761322002345
May 2022
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Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene

1
1. scibot 27 May 2022
  
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  Jackson Laboratory008449
  
  DOI: 10.1016/j.isci.2022.104391
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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sciencedirect.com/science/article/pii/S2589004222006629
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Transplantation of intestinal organoids into a mouse model of colitis

1
1. scibot 27 May 2022
  
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  Jackson laboratory (008449
  
  DOI: 10.1038/s41596-021-00658-3
  
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nature.com/articles/s41596-021-00658-3
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Lymph node colonization induces tumor-immune tolerance to promote distant metastasis

1
1. scibot 12 May 2022
  
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  Jackson Laboratories#008449
  
  DOI: 10.1016/j.cell.2022.04.019
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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sciencedirect.com/science/article/pii/S0092867422004664
Apr 2022
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ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection

1
1. scibot 21 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2022.110715
  
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sciencedirect.com/science/article/pii/S2211124722004764
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Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

1
1. scibot 20 Apr 2022
  
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  Jackson LabsStock No: 008,449
  
  DOI: 10.1016/j.celrep.2022.110695
  
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sciencedirect.com/science/article/pii/S2211124722004533
Mar 2022
www-sciencedirect-com.ezp-prod1.hul.harvard.edu www-sciencedirect-com.ezp-prod1.hul.harvard.edu

Spatial CRISPR genomics identifies regulators of the tumor microenvironment

1
1. scibot 27 Mar 2022
  
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  Jackson LaboratoriesStock# 008449
  
  DOI: 10.1016/j.cell.2022.02.015
  
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www-sciencedirect-com.ezp-prod1.hul.harvard.edu/science/article/pii/S0092867422001957
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The oxygen sensor prolyl hydroxylase domain 2 regulates the in vivo suppressive capacity of regulatory T cells

1
1. scibot 09 Mar 2022
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.7554/eLife.70555
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8896828/
Feb 2022
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Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity

1
1. scibot 16 Feb 2022
  
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  The Jackson LaboratoryJAX#008449
  
  DOI: 10.1016/j.celrep.2022.110384
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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sciencedirect.com/science/article/pii/S221112472200105X
Sep 2021
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Disruption of the endopeptidase ADAM10-Notch signaling axis leads to skin dysbiosis and innate lymphoid cell-mediated hair follicle destruction

1
1. scibot 28 Sep 2021
  
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  Jax: 008449
  
  DOI: 10.1016/j.immuni.2021.09.001
  
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sciencedirect.com/science/article/pii/S1074761321003642
Aug 2021
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Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

1
1. scibot 25 Aug 2021
  
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  JAX:008449
  
  DOI: 10.1016/j.celrep.2021.109608
  
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sciencedirect.com/science/article/pii/S2211124721010469
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

1
1. scibot 07 Aug 2021
  
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  Cat# 008449
  
  DOI: 10.1016/j.ccell.2021.07.007
  
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sciencedirect.com/science/article/pii/S1535610821003846
Jul 2021
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 31 Jul 2021
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.ccell.2019.01.006
  
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sciencedirect.com/science/article/pii/S1535610819300406
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The HVEM-BTLA Axis Restrains T Cell Help to Germinal Center B Cells and Functions as a Cell-Extrinsic Suppressor in Lymphomagenesis

1
1. scibot 28 Jul 2021
  
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  Mouse: Rag2-deficient Strain ID: B6(Cg)-Rag2tm1.1Cgn/J
  
  DOI: 10.1016/j.immuni.2019.05.022
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
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sciencedirect.com/science/article/pii/S1074761319302420
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Untitled document

1
1. scibot 27 Jul 2021
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.stem.2018.07.009
  
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sciencedirect.com/science/article/pii/S193459091830345X
Jun 2021
insight.jci.org insight.jci.org

MMP2 and TLRs modulate immune responses in the tumor microenvironment

1
1. scibot 29 Jun 2021
  
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  JAX:008449
  
  DOI: 10.1172/jci.insight.144913
  
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insight.jci.org/articles/view/144913
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Pharmacologic modulation of RNA splicing enhances anti-tumor immunity

1
1. scibot 25 Jun 2021
  
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  008449
  
  DOI: 10.1016/j.cell.2021.05.038
  
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sciencedirect.com/science/article/pii/S0092867421006905
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

T cell self-reactivity during thymic development dictates the timing of positive selection

1
1. scibot 19 May 2021
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.7554/eLife.65435
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8116051/
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Bach2 attenuates IL-2R signaling to control Treg homeostasis and Tfr development

1
1. scibot 12 May 2021
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2021.109096
  
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sciencedirect.com/science/article/pii/S2211124721004307
Apr 2021
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Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations

1
1. scibot 30 Apr 2021
  
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  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.ccell.2021.03.012
  
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sciencedirect.com/science/article/pii/S1535610821001707
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Staphylococcus cohnii is a potentially biotherapeutic skin commensal alleviating skin inflammation

1
1. scibot 28 Apr 2021
  
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  Stock No: 008449
  
  DOI: 10.1016/j.celrep.2021.109052
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721003685
Mar 2021
www.sciencedirect.com www.sciencedirect.com

Human gut mycobiota tune immunity via CARD9-dependent induction of anti-fungal IgG antibodies

1
1. scibot 29 Mar 2021
  
  in Public
  
  JAX# 008449
  
  DOI: 10.1016/j.cell.2021.01.016
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @bandrow
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S0092867421000593
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Functional characterization of the dural sinuses as a neuroimmune interface

1
1. scibot 08 Mar 2021
  
  in Public
  
  JAX008449
  
  DOI: 10.1016/j.cell.2020.12.040
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com:5037/science/article/pii/S0092867420317621
Feb 2021
academic.oup.com academic.oup.com

Immune Landscape of Pituitary Tumors Reveals Association Between Macrophages and Gonadotroph Tumor Invasion

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1210/clinem/dgaa520
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:008449
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academic.oup.com/jcem/article/105/11/dgaa520/5891780
Sep 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.celrep.2020.108186
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRIDCUR:Validated RRID:IMSR_JAX:008449
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pubmed.ncbi.nlm.nih.gov/32966792/
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PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

1
1. scibot 04 Sep 2020
  
  in Public
  
  C57BL/6 Rag2−/−
  
  DOI: 10.1016/j.immuni.2018.05.006
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Curator comments: B6(Cg)-Rag2tm1.1Cgn/J Mus musculus IMSR Cat# JAX:008449
  
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  RRIDCUR:Missing RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S1074761318302425
www.sciencedirect.com www.sciencedirect.com

Commensal Bacteria Modulate Immunoglobulin A Binding in Response to Host Nutrition

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX 008449
  
  DOI: 10.1016/j.chom.2020.03.012
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S1931312820301761
www.sciencedirect.com www.sciencedirect.com

GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation

1
1. scibot 03 Sep 2020
  
  in Public
  
  B6(Cg)-Rag2tm1.Cgn/J
  
  DOI: 10.1016/j.celrep.2020.107857
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Curator comments: B6(Cg)-Rag2tm1.1Cgn/J Mus musculus IMSR Cat# JAX:008449
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S221112472030838X
Aug 2020
www.sciencedirect.com www.sciencedirect.com

The AP1 Transcription Factor Fosl2 Promotes Systemic Autoimmunity and Inflammation by Repressing Treg Development

1
1. scibot 19 Aug 2020
  
  in Public
  
  Jax: 008449
  
  DOI: 10.1016/j.celrep.2020.107826
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Curator comments: B6(Cg)-Rag2tm1.1Cgn/J Mus musculus IMSR Cat# JAX:008449
  
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  RRIDCUR:Missing RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S221112472030807X
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of a resilient mouse facial motoneuron population following target disconnection by injury or disease

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.3233/RNN-170809
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6373730/
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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: (IMSR Cat# JAX_008449,RRID:IMSR_JAX:008449)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819300406
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response

1
1. scibot 05 Nov 2018
  
  in Public
  
  008449
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S107476131830431X
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 05 Nov 2018
  
  in Public
  
  JAX:008449
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S2211124718310854
europepmc.org europepmc.org

Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Validated
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europepmc.org/articles/PMC6015114/
www.sciencedirect.com www.sciencedirect.com

Tissue-Restricted Adaptive Type 2 Immunity Is Orchestrated by Expression of the Costimulatory Molecule OX40L on Group 2 Innate Lymphoid Cells

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S1074761318302395
europepmc.org europepmc.org

Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection.

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008449
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europepmc.org/articles/PMC5629024/
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Impact of peripheral immune status on central molecular responses to facial nerve axotomy

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:008449
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
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  RRID:IMSR_JAX:008449
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sciencedirect.com/science/article/pii/S0889159117304580
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Commensal Microbes and Hair Follicle Morphogenesis Coordinately Drive Treg Migration into Neonatal Skin

1
1. scibot 08 Nov 2017
  
  in Public
  
  B6(Cg)-Rag2tm1.1Cgn/J Cat#008449
  
  Curator: @Zeljana_Babic
  
  Resource used:
  
  RRID:IMSR_JAX:008449
  
  SciCrunch record: RRID:IMSR_JAX:008449
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:008449 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1931312817301117

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