Hypothesis

32 Matching Annotations

Sep 2026
www.sciencedirect.com www.sciencedirect.com

Apoptosis inhibition reprograms alveolar myofibroblasts toward ductal myofibroblasts

1
1. scibot 09 Sep 2026
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.celrep.2026.117891
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com/science/article/pii/S2211124726009691
Aug 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The calcium pump ATP2B1/PMCA1 regulates CNS vascular development by facilitating Norrin- and WNT7A/B-induced Frizzled4 signaling

1
1. scibot 25 Aug 2026
  
  in Public
  
  JAX:008454
  
  DOI: 10.1016/j.celrep.2026.117605
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC13469879/
www.sciencedirect.com www.sciencedirect.com

Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina

1
1. scibot 22 Aug 2026
  
  in Public
  
  Jackson Laboratory Stock_008454
  
  DOI: 10.1016/j.cub.2026.06.053
  
  Resource: RRID:IMSR_JAX:008454
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

RRIDCUR:Unresolved

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scibot

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sciencedirect.com/science/article/pii/S0960982226007992
Jul 2026
www.sciencedirect.com www.sciencedirect.com

Temporally segregated functions for Gfi1 in the development and maintenance of direction selectivity in the vertebrate retina

1
1. scibot 14 Jul 2026
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.cub.2026.06.053
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com/science/article/pii/S0960982226007992
Jun 2026
www.sciencedirect.com www.sciencedirect.com

MYCN drives pediatric glioma transformation from neural progenitors and creates distinct therapeutic vulnerabilities

1
1. scibot 13 Jun 2026
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.celrep.2026.117522
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com/science/article/pii/S2211124726006005
www.medrxiv.org www.medrxiv.org

Spermidine suppresses glial inflammation and parkinsonian abnormalities in ATP13A2 deficiency

1
1. scibot 11 Jun 2026
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.64898/2026.05.23.26353575
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

URL

medrxiv.org/content/10.64898/2026.05.23.26353575v1
Apr 2026
www.biorxiv.org www.biorxiv.org

ATP13A2 Loss of Function-Driven Polyamine Dysregulation Induces SAM Depletion and Epigenetic Astrocyte Toxicity

1
1. scibot 10 Apr 2026
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.64898/2026.04.02.716164
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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biorxiv.org/content/10.64898/2026.04.02.716164v1
Dec 2025
www.sciencedirect.com:5037 www.sciencedirect.com:5037

Cse1l is critical for cell survival, craniofacial and cardiac development

1
1. scibot 14 Dec 2025
  
  in Public
  
  JAX:008454
  
  DOI: 10.1016/j.ydbio.2025.12.007
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com:5037/science/article/pii/S0012160625003380
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Mutant RIT1 cooperates with YAP to drive an EMT-like lung cancer state

1
1. scibot 25 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.celrep.2025.116185
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

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sciencedirect.com/science/article/pii/S2211124725009568
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.103615
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12055001/
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain

1
1. scibot 02 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.celrep.2024.115016
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com/science/article/pii/S2211124724013676
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Smarcd1 subunit of SWI/SNF chromatin-remodeling complexes collaborates with E2a to promote murine lymphoid specification

1
1. scibot 04 Sep 2024
  
  in Public
  
  JAX:008454
  
  DOI: 10.1016/j.devcel.2024.08.007
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

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sciencedirect.com/science/article/pii/S1534580724004908
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Effective knockdown-replace gene therapy in a novel mouse model of DNM1 developmental and epileptic encephalopathy

1
1. scibot 23 Aug 2024
  
  in Public
  
  JAX Strain # 008454
  
  DOI: 10.1016/j.ymthe.2024.08.009
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S1525001624005318
www.sciencedirect.com www.sciencedirect.com

Mutant TP53 switches therapeutic vulnerability during gastric cancer progression within interleukin-6 family cytokines

1
1. scibot 21 Aug 2024
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.celrep.2024.114616
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724009665
Feb 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice

1
1. scibot 16 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1172/JCI171468
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10866656/
Nov 2023
www.sciencedirect.com www.sciencedirect.com

Generation of heart and vascular system in rodents by blastocyst complementation

1
1. scibot 28 Nov 2023
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1016/j.devcel.2023.10.008
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S153458072300552X
Oct 2023
www.biorxiv.org www.biorxiv.org

Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice

1
1. scibot 14 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.1101/2023.09.27.559761
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @jmitrevska
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

biorxiv.org/content/10.1101/2023.09.27.559761v1
www.embopress.org www.embopress.org

Spindle assembly checkpoint insensitivity allows meiosis-II despite chromosomal defects in aged eggs

1
1. scibot 11 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.15252/embr.202357227
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

embopress.org/doi/10.15252/embr.202357227
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function

1
1. scibot 04 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.83806
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9977283/
Aug 2022
www.sciencedirect.com www.sciencedirect.com

Cocaine increases quantal norepinephrine secretion through NET-dependent PKC activation in locus coeruleus neurons

1
1. scibot 17 Aug 2022
  
  in Public
  
  Jackson008454
  
  DOI: 10.1016/j.celrep.2022.111199
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722010166
Apr 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Neocortical Projection Neurons Instruct Inhibitory Interneuron Circuit Development in a Lineage-Dependent Manner

1
1. scibot 01 Apr 2022
  
  in Public
  
  JAX:008454
  
  DOI: 10.1016/j.neuron.2019.03.036
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8965597/
Dec 2021
www.sciencedirect.com www.sciencedirect.com

APC7 mediates ubiquitin signaling in constitutive heterochromatin in the developing mammalian brain

1
1. scibot 23 Dec 2021
  
  in Public
  
  Cat# 008454
  
  DOI: 10.1016/j.molcel.2021.11.031
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:008454
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RRIDCUR:Missing

RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S1097276521010339
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Male fertility in mice requires classical and nonclassical androgen signaling

1
1. scibot 18 Aug 2021
  
  in Public
  
  Cat# 008454
  
  DOI: 10.1016/j.celrep.2021.109557
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  What is this?
  
  RRID:IMSR_JAX:008454 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721009918
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Club cells form lung adenocarcinomas and maintain the alveoli of adult mice

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.45571
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6606035/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Loss of C9orf72 Enhances Autophagic Activity via Deregulated mTOR and TFEB Signaling

1
1. scibot 27 Jul 2021
  
  in Public
  
  008454
  
  DOI: 10.1371/journal.pgen.1006443
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @mpairish
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5119725/
May 2021
www.sciencedirect.com www.sciencedirect.com

C9orf72 regulates energy homeostasis by stabilizing mitochondrial complex I assembly

1
1. scibot 01 May 2021
  
  in Public
  
  008454
  
  DOI: 10.1016/j.cmet.2021.01.005
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:008454
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RRIDCUR:Missing

RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S155041312100005X
Feb 2021
elifesciences.org elifesciences.org

Elevated synaptic vesicle release probability in synaptophysin/gyrin family quadruple knockouts

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.40744
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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scibot

URL

elifesciences.org/articles/40744
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Partial loss of CFIm25 causes learning deficits and aberrant neuronal alternative polyadenylation

1
1. scibot 10 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.50895
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7176433/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy

1
1. scibot 09 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:008454
  
  DOI: 10.7554/eLife.48705
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

RRIDCUR:Validated

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7056272/
www.sciencedirect.com www.sciencedirect.com

Mosaic Mutant Analysis Identifies PDGFRα/PDGFRβ as Negative Regulators of Adipogenesis

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX:008454
  
  DOI: 10.1016/j.stem.2020.03.004
  
  Resource: (IMSR Cat# JAX_008454,RRID:IMSR_JAX:008454)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
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  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

sciencedirect.com/science/article/pii/S1934590920300965
Nov 2017
www.jneurosci.org www.jneurosci.org

A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles

2
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:008454
  
  Resource used:
  
  RRID:IMSR_JAX:008454
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:008454
2. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:008454
  
  Resource used:
  
  RRID:IMSR_JAX:008454
  
  SciCrunch record: RRID:IMSR_JAX:008454
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:008454
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RRID:IMSR_JAX:008454

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scibot

URL

jneurosci.org/content/36/40/10337