Hypothesis

33 Matching Annotations

Sep 2025
www.sciencedirect.com www.sciencedirect.com

Long-chain unsaturated fatty acids released during immune responses stimulate host-microbe trans-kingdom communication

1
1. scibot 19 Sep 2025
  
  in Public
  
  JAX 009088
  
  DOI: 10.1016/j.chom.2025.08.011
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

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sciencedirect.com/science/article/pii/S1931312825003373
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.cell.2025.05.016
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425005665
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Fatty Acid Derivatization and Cyclization of the Immunomodulatory Peptide RP-182 Targeting CD206high Macrophages Improve Antitumor Activity

1
1. scibot 11 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1158/1535-7163.MCT-23-0790
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11612619/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Resident Cardiac Macrophages Mediate Adaptive Myocardial Remodeling

1
1. scibot 14 Nov 2024
  
  in Public
  
  JAX:009088
  
  DOI: 10.1016/j.immuni.2021.07.003
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC8446343/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Opposing tumor-cell-intrinsic and -extrinsic roles of the IRF1 transcription factor in antitumor immunity

1
1. scibot 04 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.celrep.2024.114289
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11315447/
May 2024
www.biorxiv.org www.biorxiv.org

GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus

1
1. scibot 02 May 2024
  
  in Public
  
  009088
  
  DOI: 10.1101/2024.01.03.574062
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
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  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

biorxiv.org/content/10.1101/2024.01.03.574062v1
Mar 2024
www.sciencedirect.com www.sciencedirect.com

Bactericidal/permeability-increasing protein instructs dendritic cells to elicit Th22 cell response

2
1. scibot 08 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.celrep.2024.113929
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
2. scibot 08 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.celrep.2024.113929
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724002572
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Gut complement induced by the microbiota combats pathogens and spares commensals

1
1. scibot 06 Feb 2024
  
  in Public
  
  Mouse: B6.129P2(SJL)-Myd88tm1.1Defr/JJackson LaboratoryStock #:009088
  
  DOI: 10.1016/j.cell.2023.12.036
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424000011
Apr 2023
www.sciencedirect.com www.sciencedirect.com

A tissue injury sensing and repair pathway distinct from host pathogen defense

1
1. scibot 26 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.cell.2023.03.031
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S0092867423003288
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain

1
1. scibot 13 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.chom.2022.08.009
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1931312822004085
May 2022
www.sciencedirect.com www.sciencedirect.com

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity

1
1. scibot 19 May 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 009088
  
  DOI: 10.1016/j.celrep.2022.110837
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006106
www.sciencedirect.com www.sciencedirect.com

Activation of the transcription factor NRF2 mediates the anti-inflammatory properties of a subset of over-the-counter and prescription NSAIDs

1
1. scibot 19 May 2022
  
  in Public
  
  JAX:009088
  
  DOI: 10.1016/j.immuni.2022.04.015
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322001868
Apr 2022
www.sciencedirect.com www.sciencedirect.com

High-fat diet disrupts REG3γ and gut microbial rhythms promoting metabolic dysfunction

1
1. scibot 21 Apr 2022
  
  in Public
  
  The Jackson LaboratoryStock#009088
  
  DOI: 10.1016/j.chom.2022.03.030
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1931312822001603
Mar 2022
www.sciencedirect.com www.sciencedirect.com

Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

1
1. scibot 09 Mar 2022
  
  in Public
  
  The Jackson Laboratory009088
  
  DOI: 10.1016/j.celrep.2022.110489
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722002224
Feb 2022
www.sciencedirect.com www.sciencedirect.com

A TLR/CD44 axis regulates T cell trafficking in experimental and human multiple sclerosis

1
1. scibot 02 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.isci.2022.103763
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S2589004222000335
Dec 2021
www.sciencedirect.com www.sciencedirect.com

The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota

1
1. scibot 11 Dec 2021
  
  in Public
  
  Cat#009088
  
  DOI: 10.1016/j.xcrm.2021.100464
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2666379121003360
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
  in Public
  
  Stock#009088
  
  DOI: 10.1016/j.cmet.2021.09.002
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121004216
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation

1
1. scibot 01 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.celrep.2019.05.019
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088 RRIDCUR:Validated
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RRID:IMSR_JAX:009088

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719306308
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility

1
1. scibot 28 Jul 2021
  
  in Public
  
  009088
  
  DOI: 10.1016/j.cell.2019.01.039
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419301023
Jun 2021
www.sciencedirect.com www.sciencedirect.com

Type I interferon decreases macrophage energy metabolism during mycobacterial infection

1
1. scibot 02 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.celrep.2021.109195
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721005416
May 2021
www.sciencedirect.com www.sciencedirect.com

The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.immuni.2021.04.019
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321001813
www.sciencedirect.com www.sciencedirect.com

Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.immuni.2020.10.014
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320304556
www.sciencedirect.com www.sciencedirect.com

Neonatal Exposure to Commensal-Bacteria-Derived Antigens Directs Polysaccharide-Specific B-1 B Cell Repertoire Development

1
1. scibot 06 May 2021
  
  in Public
  
  JAX:009088
  
  DOI: 10.1016/j.immuni.2020.06.006
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320302363
www.sciencedirect.com www.sciencedirect.com

Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity

1
1. scibot 06 May 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.immuni.2020.05.001
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320301825
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Toll-Like Receptors Induce Signal-Specific Reprogramming of the Macrophage Lipidome

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.cmet.2020.05.003
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1550413120302424
www.sciencedirect.com www.sciencedirect.com

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

1
1. scibot 24 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  DOI: 10.1016/j.cell.2020.06.029
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420308060
www.sciencedirect.com www.sciencedirect.com

Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity

1
1. scibot 17 Apr 2021
  
  in Public
  
  Cat# 009088
  
  DOI: 10.1016/j.ccell.2020.05.020
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088 RRIDCUR:Missing
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610820302701
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Pairwise Stimulations of Pathogen-Sensing Pathways Predict Immune Responses to Multi-adjuvant Combinations

1
1. scibot 31 Oct 2020
  
  in Public
  
  B6.129P2(SJL)-Myd88tm1.1Defr/J
  
  DOI: 10.1016/j.cels.2020.10.001
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  Curator comments: B6.129P2(SJL)-Myd88tm1.1Defr/J Mus musculus IMSR Cat# JAX:009088
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2405471220303690
Sep 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Staphylococcus aureus ATP Synthase Promotes Biofilm Persistence by Influencing Innate Immunity

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID IMSR_JAX:009088
  
  DOI: 10.1128/mBio.01581-20
  
  Resource: (IMSR Cat# JAX_009088,RRID:IMSR_JAX:009088)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7482063/
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Alveolar Macrophages Provide an Early Mycobacterium tuberculosis Niche and Initiate Dissemination

1
1. scibot 05 Nov 2018
  
  in Public
  
  009088
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:009088
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:009088 RRIDCUR:Missing
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RRID:IMSR_JAX:009088

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1931312818304104
www.sciencedirect.com www.sciencedirect.com

Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  Resource used:
  
  RRID:IMSR_JAX:009088
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:009088
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RRID:IMSR_JAX:009088

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scibot

URL

sciencedirect.com/science/article/pii/S1931312817304419
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:009088
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:009088
  
  SciCrunch record: RRID:IMSR_JAX:009088
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:009088 RRIDCUR:Validated
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RRID:IMSR_JAX:009088

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761317303278