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7 Matching Annotations

Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

N-acetyl-l-leucine lowers α-synuclein levels and improves synaptic function in Parkinson’s disease models

1
1. scibot 03 Mar 2026
  
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  RRID:IMSR_JAX:009346
  
  DOI: 10.1172/JCI196137
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12948429/
Dec 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The R1441C-Lrrk2 mutation induces myeloid immune cell exhaustion in an age- and sex-dependent manner in mice

1
1. scibot 23 Dec 2025
  
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  RRID:IMSR_JAX:009346
  
  DOI: 10.1126/scitranslmed.adl1535
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12718673/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

N-acetyl-l-leucine lowers pS129-synuclein and improves synaptic function in models of Parkinson’s disease

1
1. scibot 21 May 2025
  
  in Public
  
  RRID:IMSR_JAX:009346
  
  DOI: 10.21203/rs.3.rs-6298077/v1
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

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scibot

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pmc.ncbi.nlm.nih.gov/articles/PMC12036458/
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathogenic LRRK2 mutations cause loss of primary cilia and Neurturin in striatal parvalbumin interneurons

1
1. scibot 22 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:009346
  
  DOI: 10.26508/lsa.202402922
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

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pmc.ncbi.nlm.nih.gov/articles/PMC11561259/
Aug 2024
www.biorxiv.org www.biorxiv.org

Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice

1
1. scibot 13 Aug 2024
  
  in Public
  
  Jackson laboratory (Stock number: 009346
  
  DOI: 10.1101/2024.07.31.606089
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  DOI:10.1101/2024.07.31.606089 RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

DOI:10.1101/2024.07.31.606089

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scibot

URL

biorxiv.org/content/10.1101/2024.07.31.606089v1
Nov 2022
www.nature.com www.nature.com

R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations

1
1. scibot 15 Nov 2022
  
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  RRID:IMSR_JAX:009346
  
  DOI: 10.1038/s42003-022-04136-8
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
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  RRID:IMSR_JAX:009346
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nature.com/articles/s42003-022-04136-8
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:009346
  
  DOI: 10.7554/eLife.67900
  
  Resource: (IMSR Cat# JAX_009346,RRID:IMSR_JAX:009346)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:009346
  
  What is this?
  
  RRID:IMSR_JAX:009346
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RRID:IMSR_JAX:009346

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC8550758/