Hypothesis

62 Matching Annotations

Mar 2026
54.241.53.176 54.241.53.176

2026.02.23.707454.full-html.html

1
1. scibot 03 Mar 2026
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.64898/2026.02.23.707454
  
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54.241.53.176/e867488402506f91f2a1273b6ec56e9f67956356/2026.02.23.707454.full-html.html
Jan 2026
dx.doi.org dx.doi.org

bqag008-html.html

1
1. scibot 23 Jan 2026
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1210/endocr/bqag008
  
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dx.doi.org/10.1210/endocr/bqag008
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Adipocyte-derived extracellular vesicles are key regulators of central leptin sensitivity and energy homeostasis

1
1. scibot 13 Nov 2025
  
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  Jax stockCat# 012899
  
  DOI: 10.1016/j.cmet.2025.10.005
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1550413125004395
www.sciencedirect.com www.sciencedirect.com

Noradrenergic control of bone marrow and thymus by AgRP neurons is impaired in experimental multiple sclerosis

1
1. scibot 13 Nov 2025
  
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  The Jackson LaboratoriesStrain # 012899
  
  DOI: 10.1016/j.celrep.2025.116556
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S2211124725013270
Oct 2025
www.sciencedirect.com www.sciencedirect.com

Hunger modulates exploration through suppression of dopamine signaling in the tail of the striatum

1
1. scibot 08 Oct 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2025.09.009
  
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sciencedirect.com/science/article/pii/S089662732500697X
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Identification of a neural basis for energy expenditure in the mouse arcuate hypothalamus

1
1. scibot 18 Sep 2025
  
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  JAX:012899
  
  DOI: 10.1016/j.neuron.2025.08.021
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
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sciencedirect.com/science/article/pii/S0896627325006300
www.sciencedirect.com www.sciencedirect.com

Age-specific regulation of sociability by hypothalamic Agrp neurons

1
1. scibot 04 Sep 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.cub.2025.08.014
  
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sciencedirect.com/science/article/pii/S0960982225010802
Jul 2025
www.embopress.org www.embopress.org

FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons | The EMBO Journal

1
1. scibot 15 Jul 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1038/s44318-025-00503-3
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @dhovakimyan1
  
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embopress.org/doi/full/10.1038/s44318-025-00503-3
www.embopress.org www.embopress.org

FTO promotes weight gain via altering Kif1a splicing and axonal vesicle trafficking in AgRP neurons

1
1. scibot 15 Jul 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1038/s44318-025-00503-3
  
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embopress.org/doi/10.1038/s44318-025-00503-3
link.springer.com link.springer.com

Brain-wide input-output analysis of tuberal nucleus somatostatin neurons reveals hierarchical circuits for orchestrating feeding behavior

1
1. scibot 03 Jul 2025
  
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  JAX:012899
  
  DOI: 10.1038/s41467-025-60585-9
  
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link.springer.com/article/10.1038/s41467-025-60585-9
Jun 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia are required for developmental specification of AgRP innervation in the hypothalamus of offspring exposed to maternal high-fat diet during lactation

1
1. scibot 18 Jun 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.7554/eLife.101391
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12169846/
www.sciencedirect.com www.sciencedirect.com

Distinct neural representations of hunger and thirst in neonatal mice before the emergence of food- and water-seeking behaviors

1
1. scibot 11 Jun 2025
  
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  Strain: 012899
  
  DOI: 10.1016/j.cub.2025.05.042
  
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  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S096098222500658X
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 11 Jun 2025
  
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  Stock# 012899
  
  DOI: 10.1210/endocr/bqaf104
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @sjvitug
  
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52.53.155.43/7495924e48620f45541fa9b3bb0dd61e0f990a40/PDF-html.html
May 2025
www.sciencedirect.com www.sciencedirect.com

The gut-brain axis mechanism of normal appetite induced by kynurenic acid

1
1. scibot 16 May 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.celrep.2025.115659
  
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sciencedirect.com/science/article/pii/S2211124725004309
Apr 2025
www.sciencedirect.com www.sciencedirect.com

Hypothalamic PNOC/NPY neurons constitute mediators of leptin-controlled energy homeostasis

1
1. scibot 24 Apr 2025
  
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  012899
  
  DOI: 10.1016/j.cell.2025.04.001
  
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  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S0092867425004039
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Microglia are Required for Developmental Specification of AgRP Innervation in the Hypothalamus of Offspring Exposed to Maternal High Fat Diet During Lactation

1
1. scibot 13 Mar 2025
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1101/2024.08.12.607566
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11343114/
www.sciencedirect.com www.sciencedirect.com

A cellular and molecular basis of leptin resistance

1
1. scibot 06 Mar 2025
  
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  Jackson LaboratoryCat# 012899
  
  DOI: 10.1016/j.cmet.2025.01.001
  
  Resource: RRID:IMSR_JAX:012899
  
  Curator: @areedewitt04
  
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sciencedirect.com/science/article/pii/S1550413125000014
Dec 2024
www.sciencedirect.com www.sciencedirect.com

Acute and circadian feedforward regulation of agouti-related peptide hunger neurons

1
1. scibot 24 Dec 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.cmet.2024.11.009
  
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  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413124004558
Sep 2024
www.biorxiv.org www.biorxiv.org

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis

1
1. scibot 28 Sep 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1101/2024.09.19.613929
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
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biorxiv.org/content/10.1101/2024.09.19.613929v1
Aug 2024
www.sciencedirect.com www.sciencedirect.com

Negative feedback control of hypothalamic feeding circuits by the taste of food

1
1. scibot 22 Aug 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2024.07.017
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
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sciencedirect.com/science/article/pii/S0896627324005397
academic.oup.com academic.oup.com

Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice

1
1. scibot 02 Aug 2024
  
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  AgRP-cre
  
  DOI: 10.1210/en.2019-00100
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:012899 RRIDCUR:Missing
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academic.oup.com/endo/advance-article/doi/10.1210/en.2019-00100/5487353
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Repeated stress triggers seeking of a starvation-like state in anxiety-prone female mice

1
1. scibot 23 Apr 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2024.03.027
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
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sciencedirect.com/science/article/pii/S0896627324002344
www.sciencedirect.com www.sciencedirect.com

Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss

1
1. scibot 04 Apr 2024
  
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  Strain #:012899
  
  DOI: 10.1016/j.cmet.2024.02.007
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S1550413124000536
Feb 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Androgen receptor actions on AgRP neurons are not a major cause of reproductive and metabolic impairments in peripubertally androgenized mice

1
1. scibot 18 Feb 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1111/jne.13370
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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onlinelibrary.wiley.com/doi/10.1111/jne.13370
Jan 2024
www.sciencedirect.com www.sciencedirect.com

Phosphorylation of pyruvate dehydrogenase inversely associates with neuronal activity

1
1. scibot 25 Jan 2024
  
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  Mouse: AgRP-IRES-CreJackson LaboratoryCat# 012899
  
  DOI: 10.1016/j.neuron.2023.12.015
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S0896627323009741
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Opioidergic signaling contributes to food-mediated suppression of AgRP neurons

1
1. scibot 06 Jan 2024
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.celrep.2023.113630
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10865729/
www.sciencedirect.com www.sciencedirect.com

Agrp-negative arcuate NPY neurons drive feeding under positive energy balance via altering leptin responsiveness in POMC neurons

1
1. scibot 04 Jan 2024
  
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  012899
  
  DOI: 10.1016/j.cmet.2023.04.020
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S1550413123001778
journals.physiology.org journals.physiology.org

Krüppel-like factor 4 (KLF4) in Transcriptional Control of The Three Unique Isoforms of Agouti-Related Peptide (Agrp) in Mice | Physiological Genomics

1
1. scibot 02 Jan 2024
  
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  10.1152/physiolgenomics.00042.2023
  
  DOI: 10.1152/physiolgenomics.00042.2023
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @bandrow
  
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journals.physiology.org/doi/abs/10.1152/physiolgenomics.00042.2023
Dec 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Negative feedback control of hunger circuits by the taste of food

1
1. scibot 20 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:012899
  
  DOI: 10.1101/2023.11.30.569492
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10705440/
Jul 2023
www.sciencedirect.com www.sciencedirect.com

AgRP neurons are not indispensable for body weight maintenance in adult mice

1
1. scibot 12 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.celrep.2023.112789
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124723008008
Jun 2023
onlinelibrary.wiley.com onlinelibrary.wiley.com

Fasting and prolonged food restriction differentially affect GH secretion independently of GH receptor signaling in AgRP neurons

1
1. scibot 01 Jun 2023
  
  in Public
  
  RRID:IMSR_JAX:012899
  
  DOI: 10.1111/jne.13254
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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onlinelibrary.wiley.com/doi/10.1111/jne.13254
Mar 2023
www.sciencedirect.com www.sciencedirect.com

A synaptic amplifier of hunger for regaining body weight in the hypothalamus

1
1. scibot 28 Mar 2023
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.cmet.2023.03.002
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1550413123000803
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Regional and cell-type-specific afferent and efferent projections of the mouse claustrum

1
1. scibot 17 Feb 2023
  
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  JAX:012899
  
  DOI: 10.1016/j.celrep.2023.112118
  
  Resource: (IMSR Cat# JAX_012899,RRID:IMSR_JAX:012899)
  
  Curator: @scibot
  
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  RRID:IMSR_JAX:012899
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sciencedirect.com/science/article/pii/S2211124723001298
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Food-induced dopamine signaling in AgRP neurons promotes feeding

1
1. scibot 01 Dec 2022
  
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  RRID:IMSR_JAX:012
  
  DOI: 10.1016/j.celrep.2022.111718
  
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sciencedirect.com/science/article/pii/S2211124722015960
Oct 2022
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Hypothalamic AgRP neurons exert top-down control on systemic TNF-α release during endotoxemia

1
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  DOI: 10.1016/j.cub.2022.09.017
  
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Sep 2022
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Regulation of body weight and food intake by AGRP neurons during opioid dependence and abstinence in mice

1
1. scibot 21 Sep 2022
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.3389/fncir.2022.977642
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9468932/
Mar 2022
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Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor

1
1. scibot 27 Mar 2022
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.cmet.2022.02.012
  
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Feb 2022
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Simple method to induce denaturation of fluorescent proteins in free-floating brain slices

1
1. scibot 13 Feb 2022
  
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  RRID: IMSR_JAX: 012899
  
  DOI: 10.1016/j.jneumeth.2022.109500
  
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Dec 2021
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EASI-FISH for thick tissue defines lateral hypothalamus spatio-molecular organization

1
1. scibot 07 Dec 2021
  
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  DOI: 10.1016/j.cell.2021.11.024
  
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Neural basis for regulation of vasopressin secretion by anticipated disturbances in osmolality

1
1. scibot 24 Nov 2021
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.7554/eLife.66609
  
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An mPOA-ARCAgRP pathway modulates cold-evoked eating behavior

1
1. scibot 15 Aug 2021
  
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  JAX:012899
  
  DOI: 10.1016/j.celrep.2021.109502
  
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Ghrelin-Induced Food Intake, But not GH Secretion, Requires the Expression of the GH Receptor in the Brain of Male Mice

1
1. scibot 05 Aug 2021
  
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  RRID:IMSR_JAX
  
  DOI: 10.1210/endocr/bqab097
  
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academic.oup.com/endo/article/162/7/bqab097/6273366
Jul 2021
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Untitled document

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1. scibot 31 Jul 2021
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2019.02.028
  
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Hypothalamic control of interoceptive hunger

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1. scibot 17 Jul 2021
  
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  DOI: 10.1016/j.cub.2021.06.048
  
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A neural circuit for excessive feeding driven by environmental context in mice

2
1. scibot 01 Jul 2021
  
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  JAX:012899
  
  DOI: 10.1038/s41593-021-00875-9
  
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2. scibot 01 Jul 2021
  
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  DOI: 10.1038/s41593-021-00875-9
  
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nature.com/articles/s41593-021-00875-9
Jan 2021
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Cold-induced hyperphagia requires AgRP neuron activation in mice

1
1. scibot 30 Jan 2021
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.7554/eLife.58764
  
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Sep 2020
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The p75 neurotrophin receptor in AgRP neurons is necessary for homeostatic feeding and food anticipation

1
1. scibot 23 Sep 2020
  
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  DOI: 10.7554/eLife.52623
  
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onlinelibrary.wiley.com onlinelibrary.wiley.com

Projections from the Dorsomedial Division of the Bed Nucleus of the Stria Terminalis to Hypothalamic Nuclei in the Mouse

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1. scibot 10 Sep 2020
  
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  DOI: 10.1002/cne.24988
  
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onlinelibrary.wiley.com/doi/10.1002/cne.24988
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PNOCARC Neurons Promote Hyperphagia and Obesity upon High-Fat-Diet Feeding

1
1. scibot 04 Sep 2020
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2020.03.022
  
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Obesity causes selective and long-lasting desensitization of AgRP neurons to dietary fat

1
1. scibot 03 Sep 2020
  
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  Jackson LabsStock No:012899
  
  DOI: 10.7554/eLife.55909
  
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elifesciences.org/articles/55909
Jan 2020
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DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1038/s41467-019-13339-3
  
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Natural and Drug Rewards Engage Distinct Pathways that Converge on Coordinated Hypothalamic and Reward Circuits

1
1. scibot 13 Jan 2020
  
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  RRID:IMSR_JAX:012899
  
  DOI: 10.1016/j.neuron.2019.05.050
  
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Sustained NPY signaling enables AgRP neurons to drive feeding

1
1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.46348
  
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Untitled document

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1. scibot 12 Jan 2020
  
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  DOI: 10.1016/j.neuron.2019.02.028
  
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sciencedirect.com/science/article/pii/S0896627319301631
Nov 2018
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A Neural Circuit for Gut-Induced Reward

1
1. scibot 05 Nov 2018
  
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Carnitine acetyltransferase in Agrp neurons is required for the homeostatic adaptation to restricted feeding in male mice

1
1. scibot 05 Nov 2018
  
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  RRID:IMSR_JAX:012899
  
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academic.oup.com/endo/article/159/6/2473/4982118
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Ancestral Circuits for the Coordinated Modulation of Brain State

1
1. scibot 05 Nov 2018
  
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  Jax stock: # 012899
  
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Nov 2017
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Dynamics of Gut-Brain Communication Underlying Hunger

1
1. scibot 08 Nov 2017
  
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  RRID:IMSR_JAX:012899
  
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Aldosterone-Sensing Neurons in the NTS Exhibit State-Dependent Pacemaker Activity and Drive Sodium Appetite via Synergy with Angiotensin II Signaling

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0896627317308541
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A Hypothalamic Phosphatase Switch Coordinates Energy Expenditure with Feeding

1
1. scibot 08 Nov 2017
  
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High-frequency stimulation-induced peptide release synchronizes arcuate kisspeptin neurons and excites GnRH neurons

1
1. scibot 08 Nov 2017
  
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  IMSR_JAX:012899
  
  Curator: @gabimpine
  
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elifesciences.org/content/5/e16246