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71 Matching Annotations

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aacrjournals.org aacrjournals.org

TIGIT affects CAR NK cell effector function in the solid tumor microenvironment by modulating immune synapse strength

1
1. scibot 23 Apr 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2326-6066.CIR-24-0919
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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aacrjournals.org/cancerimmunolres/article/13/10/1576/765472/TIGIT-Affects-CAR-NK-cell-Effector-Function-in-the
Apr 2026
www.science.org www.science.org

Claudins interact with LILRB immune inhibitory receptors to promote myeloid immunosuppression in cancer

1
1. scibot 07 Apr 2026
  
  in Public
  
  013062
  
  DOI: 10.1126/sciimmunol.adt7832
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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science.org/doi/10.1126/sciimmunol.adt7832
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A novel humanized immune stroma PDX cancer model for therapeutic studies

1
1. scibot 27 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1007/s00262-026-04349-4
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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pmc.ncbi.nlm.nih.gov/articles/PMC13013731/
www.sciencedirect.com www.sciencedirect.com

FASN inactivation-induced progranulin (GRN) expression promotes lysosome-dependent cell death to suppress leukemogenesis

1
1. scibot 05 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.celrep.2026.117042
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2211124726001208
Feb 2026
www.sciencedirect.com www.sciencedirect.com

CRISPR-based functional genomics for dissecting therapeutic dependency in primary acute myeloid leukemia samples

1
1. scibot 27 Feb 2026
  
  in Public
  
  JAXStrain #:013062
  
  DOI: 10.1016/j.molcel.2026.02.003
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S1097276526000985
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SF3B1K700E neoantigen is a CD8+ T-cell target shared across human myeloid neoplasms

1
1. scibot 04 Feb 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2326-6066.CIR-24-0091
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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pmc.ncbi.nlm.nih.gov/articles/PMC12858050/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

1
1. scibot 01 Feb 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1038/s41467-025-66966-4
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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pmc.ncbi.nlm.nih.gov/articles/PMC12783633/
Jan 2026
www.sciencedirect.com www.sciencedirect.com

Retinal determination network reactivation drives chemoresistance and blocks myeloid differentiation in acute myeloid leukemia

1
1. scibot 23 Jan 2026
  
  in Public
  
  The Jackson LaboratoryStrain#: 013062
  
  DOI: 10.1016/j.celrep.2025.116875
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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scibot

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sciencedirect.com/science/article/pii/S221112472501647X
www.sciencedirect.com www.sciencedirect.com

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia

1
1. scibot 09 Jan 2026
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xcrm.2025.102540
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2666379125006135
www.sciencedirect.com www.sciencedirect.com

Discovery, delineation, and therapeutic targeting of a hyper-translation pathway driving cytokine release syndrome

1
1. scibot 06 Jan 2026
  
  in Public
  
  JAX:013062
  
  DOI: 10.1016/j.xcrm.2025.102531
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2666379125006044
Nov 2025
www.sciencedirect.com www.sciencedirect.com

Disparate leukemia mutations converge on nuclear phase-separated condensates

1
1. scibot 05 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.cell.2025.10.010
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S0092867425011493
Oct 2025
www.sciencedirect.com www.sciencedirect.com

A generalized strategy to kill leukemic cells by targeting the regulatory systems governing mitochondrial membrane potential

1
1. scibot 30 Oct 2025
  
  in Public
  
  The Jackson LaboratoryStock No. 013062
  
  DOI: 10.1016/j.celrep.2025.116496
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2211124725012677
www.biorxiv.org www.biorxiv.org

Co-targeting menin and LSD1 dismantles oncogenic programs and restores differentiation in MLL-rearranged AML

1
1. scibot 23 Oct 2025
  
  in Public
  
  Jackson Laboratories #: 013062
  
  DOI: 10.1101/2025.10.13.681683
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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biorxiv.org/content/10.1101/2025.10.13.681683v1
www.science.org www.science.org

Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia

1
1. scibot 21 Oct 2025
  
  in Public
  
  013062
  
  DOI: 10.1126/sciadv.adx8662
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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science.org/doi/10.1126/sciadv.adx8662
Sep 2025
www.sciencedirect.com www.sciencedirect.com

FLT3L-based drug conjugate effectively targets chemoresistant leukemia stem cells in acute myeloid leukemia

1
1. scibot 23 Sep 2025
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xcrm.2025.102365
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2666379125004380
Aug 2025
www.sciencedirect.com www.sciencedirect.com

Multimodal targeting of metastatic renal cell carcinoma via CD70-directed allogeneic CAR-NKT cells

1
1. scibot 30 Aug 2025
  
  in Public
  
  The Jackson LaboratoryStrain #: 013062
  
  DOI: 10.1016/j.xcrm.2025.102321
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2666379125003945
onlinelibrary.wiley.com onlinelibrary.wiley.com

Mesenchymal stromal cells from JAK2V617F myeloproliferative neoplasms support healthy and malignant hematopoiesis in a humanized scaffold model in vivo

1
1. scibot 27 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1002/hem3.70185
  
  Resource: None
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:013062
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RRIDCUR:Unresolved

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scibot

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onlinelibrary.wiley.com/doi/10.1002/hem3.70185
Jul 2025
www.cell.com www.cell.com

Combination antiretroviral therapy and MCL-1 inhibition mitigate HTLV-1 infection in vivo

1
1. scibot 15 Jul 2025
  
  in Public
  
  Strain# 013062
  
  DOI: 10.1016/j.cell.2025.06.023
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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cell.com/cell/abstract/S0092-8674(25)00689-0
May 2025
www.cell.com www.cell.com

CD97-directed CAR-T cells with enhanced persistence eradicate acute myeloid leukemia in diverse xenograft models

2
1. scibot 29 May 2025
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xcrm.2025.102148
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
2. scibot 29 May 2025
  
  in Public
  
  The Jackson Laboratory Cat_013062
  
  DOI: 10.1016/j.xcrm.2025.102148
  
  Resource: None
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Unresolved
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RRID:IMSR_JAX:013062

RRIDCUR:Unresolved

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scibot

URL

cell.com/cell-reports-medicine/fulltext/S2666-3791(25)00221-6
www.sciencedirect.com www.sciencedirect.com

A comprehensive engineering strategy improves potency and manufacturability of a near pan-neutralizing antibody against HIV

1
1. scibot 16 May 2025
  
  in Public
  
  Jackson LaboratoriesStrain #013062
  
  DOI: 10.1016/j.str.2025.04.016
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S0969212625001509
Dec 2024
onlinelibrary.wiley.com onlinelibrary.wiley.com

Nuclear Control of Mitochondrial Homeostasis and Venetoclax Efficacy in AML via COX4I1

1
1. scibot 29 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1002/advs.202404620
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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onlinelibrary.wiley.com/doi/full/10.1002/advs.202404620
www.sciencedirect.com www.sciencedirect.com

A human-like glutaminase-free asparaginase is highly efficacious in ASNSlow leukemia and solid cancer mouse xenograft models

1
1. scibot 21 Dec 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.canlet.2024.217404
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S0304383524007997
www.sciencedirect.com www.sciencedirect.com

Modulation of TCR stimulation and pifithrin-α improves the genomic safety profile of CRISPR-engineered human T cells

1
1. scibot 05 Dec 2024
  
  in Public
  
  JAX:013062
  
  DOI: 10.1016/j.xcrm.2024.101846
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2666379124006177
Nov 2024
www.sciencedirect.com www.sciencedirect.com

Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint

1
1. scibot 24 Nov 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.immuni.2024.10.013
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S107476132400493X
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Customised design of antisense oligonucleotides targeting EGFR driver mutants for personalised treatment of non-small cell lung cancer

1
1. scibot 25 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.ebiom.2024.105356
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRIDCUR:Unresolved RRID:IMSR_JAX:013062
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RRIDCUR:Unresolved

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scibot

URL

sciencedirect.com/science/article/pii/S235239642400392X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Psoriatic arthritis subtypes are phenocopied in humanized mice

1
1. scibot 15 Sep 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1172/jci.insight.178213
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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ncbi.nlm.nih.gov/pmc/articles/PMC11383598/
Jun 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

B7-H3–Targeting Chimeric Antigen Receptors Epstein-Barr Virus–specific T Cells Provides a Tumor Agnostic Off-The-Shelf Therapy Against B7-H3–positive Solid Tumors

1
1. scibot 09 Jun 2024
  
  in Public
  
  RRID 013062
  
  DOI: 10.1158/2767-9764.CRC-23-0538
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  DOI:10.1158/2767-9764.CRC-23-0538 RRID:IMSR_JAX:013062
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RRID:IMSR_JAX:013062

DOI:10.1158/2767-9764.CRC-23-0538

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC11149603/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

Putting the STING back into BH3-mimetic drugs for TP53-mutant blood cancers

1
1. scibot 26 Apr 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.ccell.2024.04.004
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S1535610824001284
www.sciencedirect.com www.sciencedirect.com

Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer

1
1. scibot 25 Apr 2024
  
  in Public
  
  Jackson LaboratoryStrain# 013062
  
  DOI: 10.1016/j.stem.2024.03.018
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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RRID:IMSR_JAX:013062

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scibot

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sciencedirect.com/science/article/pii/S1934590924001243
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice

1
1. scibot 12 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1038/s42003-024-06006-x
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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RRID:IMSR_JAX:013062

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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10924958/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy

1
1. scibot 06 Mar 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2159-8290.CD-22-1297
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062
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URL

ncbi.nlm.nih.gov/pmc/articles/PMC10527971/
www.sciencedirect.com www.sciencedirect.com

The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression

1
1. scibot 01 Mar 2024
  
  in Public
  
  The Jackson Laboratory13062
  
  DOI: 10.1016/j.cell.2024.01.048
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S009286742400117X
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Peptide-scFv antigen recognition domains effectively confer CAR T cell multiantigen specificity

1
1. scibot 13 Feb 2024
  
  in Public
  
  The Jackson LaboratoryCat#013062
  
  DOI: 10.1016/j.xcrm.2024.101422
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S2666379124000454
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML

1
1. scibot 02 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/1078-0432.CCR-22-3929
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10524644/
Jan 2024
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Therapeutic application of human type 2 innate lymphoid cells via induction of granzyme B-mediated tumor cell death

1
1. scibot 11 Jan 2024
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.cell.2023.12.015
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S0092867423013478
Dec 2023
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SON is an essential m6A target for hematopoietic stem cell fate

1
1. scibot 17 Dec 2023
  
  in Public
  
  The Jackson LaboratoryStrain # 013062
  
  DOI: 10.1016/j.stem.2023.11.006
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S1934590923003983
Nov 2023
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Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML

1
1. scibot 22 Nov 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xcrm.2023.101290
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S2666379123004846
Oct 2023
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Cooperative CAR targeting to selectively eliminate AML and minimize escape

1
1. scibot 13 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.ccell.2023.09.010
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1535610823003264
Sep 2023
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CBFA2T3-GLIS2-dependent pediatric acute megakaryoblastic leukemia is driven by GLIS2 and sensitive to navitoclax

1
1. scibot 19 Sep 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.celrep.2023.113084
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S2211124723010951
Apr 2023
aacrjournals.org aacrjournals.org

Dual mTORC1/2 inhibition synergistically enhances AML cell death in combination with the BCL2 antagonist venetoclax

1
1. scibot 21 Apr 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/1078-0432.CCR-22-2729
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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aacrjournals.org/clincancerres/article/29/7/1332/718764/Dual-mTORC1-2-Inhibition-Synergistically-Enhances
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses

1
1. scibot 18 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.21203/rs.3.rs-2518774/v1
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9980221/
Feb 2023
www.sciencedirect.com www.sciencedirect.com

Reversal of malignant ADAR1 splice isoform switching with Rebecsinib

1
1. scibot 17 Feb 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2023.01.008
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1934590923000085
www.biorxiv.org www.biorxiv.org

Bacteriophage therapy for the treatment of Mycobacterium tuberculosis infections in humanized mice

1
1. scibot 07 Feb 2023
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1101/2023.01.23.525188
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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biorxiv.org/content/10.1101/2023.01.23.525188v1
Dec 2022
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Expression of inducible factors reprograms CAR-T cells for enhanced function and safety

1
1. scibot 13 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.ccell.2022.11.006
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1535610822005530
Nov 2022
www.embopress.org www.embopress.org

Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T-cell lymphoma

1
1. scibot 12 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.15252/emmm.202115200
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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embopress.org/doi/10.15252/emmm.202115200
Apr 2022
aacrjournals.org aacrjournals.org

Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia

1
1. scibot 05 Apr 2022
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2159-8290.CD-21-0692
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
Mar 2022
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Lamin B1 deletion in myeloid neoplasms causes nuclear anomaly and altered hematopoietic stem cell function

1
1. scibot 18 Mar 2022
  
  in Public
  
  Jackson labscat#: 013062
  
  DOI: 10.1016/j.stem.2022.02.010
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S1934590922000613
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Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML

1
1. scibot 09 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.celrep.2022.110481
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S2211124722002145
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Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma

1
1. scibot 04 Mar 2022
  
  in Public
  
  RRID:IMSR_JAX:013062Info
  
  DOI: 10.1016/j.ymthe.2022.02.005
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @sophiastull
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1525001622000880
Feb 2022
www.sciencedirect.com www.sciencedirect.com

An oncogenic enhancer encodes selective selenium dependency in AML

1
1. scibot 02 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2022.01.003
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1934590922000030
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions

1
1. scibot 16 Jan 2022
  
  in Public
  
  The Jackson LaboratoryCat# 013062
  
  DOI: 10.1016/j.crmeth.2021.100153
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @sophiastull
  
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sciencedirect.com/science/article/pii/S2667237521002307
Aug 2021
www.sciencedirect.com www.sciencedirect.com

TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate

1
1. scibot 04 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2021.07.003
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1934590921002885
Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.ccell.2018.10.005
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Jmenke
  
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  RRIDCUR:Validated RRID:IMSR_JAX:013062
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ncbi.nlm.nih.gov/pmc/articles/PMC6280965/
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JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  013062
  
  DOI: 10.1016/j.ccell.2018.10.008
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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  RRIDCUR:Missing RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S1535610818304744
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AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2018.05.021
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S193459091830239X
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2159-8290.CD-20-1353
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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cancerdiscovery.aacrjournals.org/content/11/6/1398
May 2021
www.sciencedirect.com www.sciencedirect.com

Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow

1
1. scibot 15 May 2021
  
  in Public
  
  Stock No: 013062
  
  DOI: 10.1016/j.immuni.2020.07.017
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Naa003
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1074761320303241
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Nicotinamide Metabolism Mediates Resistance to Venetoclax in Relapsed Acute Myeloid Leukemia Stem Cells

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2020.07.021
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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sciencedirect.com/science/article/pii/S1934590920303593
Apr 2021
rupress.org rupress.org

Human KIT+ myeloid cells facilitate visceral metastasis by melanoma

1
1. scibot 24 Apr 2021
  
  in Public
  
  JAX:013062
  
  DOI: 10.1084/jem.20182163
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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rupress.org/jem/article/218/6/e20182163/211995/Human-KIT-myeloid-cells-facilitate-visceral
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Telomere Stress Potentiates STING-Dependent Anti-tumor Immunity

1
1. scibot 17 Apr 2021
  
  in Public
  
  Cat# 013062
  
  DOI: 10.1016/j.ccell.2020.05.020
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Naa003
  
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  RRIDCUR:Missing RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S1535610820302701
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells

1
1. scibot 28 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1158/2643-3230.BCD-20-0161
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Enriching for human acute myeloid leukemia stem cells using reactive oxygen species-based cell sorting

1
1. scibot 05 Jan 2021
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xpro.2020.100248
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666166720302355
Sep 2020
www.sciencedirect.com www.sciencedirect.com

RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.stem.2020.04.009
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S193459092030148X
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Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.xcrm.2020.100003
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2666379120300033
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow

1
1. scibot 03 Sep 2020
  
  in Public
  
  013062
  
  DOI: 10.1016/j.celrep.2018.07.097
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
  Curator comments: NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/MloySzJ Mus musculus IMSR Cat# JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Missing
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ncbi.nlm.nih.gov/pmc/articles/PMC6542273/
Aug 2020
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CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia

1
1. scibot 17 Aug 2020
  
  in Public
  
  Mouse: NSG-SGM3 (NOD.Cg-Prkdcscid Il2rgtm1Wjl Tg(CMV-IL3,CSF2,KITLG)1Eav/MloySzJ)
  
  DOI: 10.1016/j.celrep.2019.12.026
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRIDCUR:Missing RRID:IMSR_JAX:013062
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sciencedirect.com/science/article/pii/S2211124719316766
Jan 2020
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  JAX:013062
  
  DOI: 10.1016/j.stem.2018.12.003
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @ethanbadger
  
  SciCrunch record: JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590918305939
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:013062
  
  DOI: 10.1016/j.ccell.2018.10.005
  
  Resource: (IMSR Cat# JAX_013062,RRID:IMSR_JAX:013062)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6280965/
Nov 2018
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Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance

1
1. scibot 05 Nov 2018
  
  in Public
  
  013062
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:013062
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590918303874
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SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function

1
1. scibot 05 Nov 2018
  
  in Public
  
  013062
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:013062
  
  SciCrunch record: RRID:IMSR_JAX:013062
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:IMSR_JAX:013062 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1934590918303850

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