Hypothesis

15 Matching Annotations

May 2025
www.sciencedirect.com www.sciencedirect.com

Chromatin modification abnormalities by CHD7 and KMT2C loss promote medulloblastoma progression

1
1. scibot 20 May 2025
  
  in Public
  
  The Jackson LaboratoryJAX No. 013593
  
  DOI: 10.1016/j.celrep.2025.115673
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725004449
www.sciencedirect.com www.sciencedirect.com

Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target

1
1. scibot 17 May 2025
  
  in Public
  
  The Jackson LaboratoryStrain #:013593
  
  DOI: 10.1016/j.ccell.2025.04.014
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825001734
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Siah2 antagonism of Pard3/JamC modulates Ntn1-Dcc signaling to regulate cerebellar granule neuron germinal zone exit

1
1. scibot 16 Jan 2025
  
  in Public
  
  JAX:013593
  
  DOI: 10.1038/s41467-024-55400-w
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11706986/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Antagonistic action of Siah2 and Pard3/JamC to promote germinal zone exit of differentiated cerebellar granule neurons by modulating Ntn1 signaling via Dcc

1
1. scibot 07 Nov 2024
  
  in Public
  
  JAX:013593
  
  DOI: 10.21203/rs.3.rs-1819367/v1
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11469462/
Aug 2024
www.sciencedirect.com www.sciencedirect.com

A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain

1
1. scibot 19 Aug 2024
  
  in Public
  
  RRID:IMSR_JAX:013593
  
  DOI: 10.1016/j.devcel.2024.07.007
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S153458072400443X
Jun 2024
www.sciencedirect.com www.sciencedirect.com

Cancer-specific epigenome identifies oncogenic hijacking by nuclear factor I family proteins for medulloblastoma progression

1
1. scibot 04 Jun 2024
  
  in Public
  
  013593
  
  DOI: 10.1016/j.devcel.2024.05.013
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  DOI:10.1016/j.devcel.2024.05.013 RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

DOI:10.1016/j.devcel.2024.05.013

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scibot

URL

sciencedirect.com/science/article/pii/S1534580724003307
Mar 2023
www.biorxiv.org www.biorxiv.org

Spatiotemporal dynamics of sensory neuron and Merkel-cell remodeling are decoupled during epidermal homeostasis

1
1. scibot 31 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:013593
  
  DOI: 10.1101/2023.02.14.528558
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
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  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

biorxiv.org/content/10.1101/2023.02.14.528558v1
Jan 2022
www.sciencedirect.com www.sciencedirect.com

IL-17RA-signaling in Lgr5+ intestinal stem cells induces expression of transcription factor ATOH1 to promote secretory cell lineage commitment

1
1. scibot 27 Jan 2022
  
  in Public
  
  Cat#: 013593
  
  DOI: 10.1016/j.immuni.2021.12.016
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321005525
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Enhancer decommissioning imposes an epigenetic barrier to sensory hair cell regeneration

1
1. scibot 15 Aug 2021
  
  in Public
  
  JAX:013593
  
  DOI: 10.1016/j.devcel.2021.07.003
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  What is this?
  
  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S1534580721005591
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics

1
1. scibot 14 Jul 2021
  
  in Public
  
  Strain# 013593
  
  DOI: 10.1016/j.celrep.2021.109358
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721007567
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX: 013593
  
  DOI: 10.1016/j.neuron.2020.02.025
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  What is this?
  
  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S0896627320301483
www.sciencedirect.com www.sciencedirect.com

Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth

1
1. scibot 03 Sep 2020
  
  in Public
  
  JAX#013593
  
  DOI: 10.1016/j.cell.2019.12.024
  
  Resource: (IMSR Cat# JAX_013593,RRID:IMSR_JAX:013593)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  What is this?
  
  RRID:IMSR_JAX:013593
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RRID:IMSR_JAX:013593

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scibot

URL

sciencedirect.com/science/article/pii/S0092867419313868
Nov 2018
europepmc.org europepmc.org

Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:013593
  
  Curator: @evieth
  
  Resource used:
  
  RRID:IMSR_JAX:013593
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013593 RRIDCUR:Validated
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RRID:IMSR_JAX:013593

RRIDCUR:Validated

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scibot

URL

europepmc.org/articles/PMC5736349/
Nov 2017
elifesciences.org elifesciences.org

Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:013593
  
  Curator: @gabimpine
  
  Resource used:
  
  RRID:IMSR_JAX:013593
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013593 RRIDCUR:Validated
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RRID:IMSR_JAX:013593

RRIDCUR:Validated

Annotators

scibot

URL

elifesciences.org/content/6/e18128
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:013593
  
  Curator: @gabimpine
  
  Resource used:
  
  RRID:IMSR_JAX:013593
  
  SciCrunch record: RRID:IMSR_JAX:013593
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:013593 RRIDCUR:Validated
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RRID:IMSR_JAX:013593

RRIDCUR:Validated

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5215100/