Hypothesis

15 Matching Annotations

Aug 2026
www.sciencedirect.com www.sciencedirect.com

The coordinated actions of metformin in the intestine and liver improves hyperglycemia

1
1. scibot 08 Aug 2026
  
  in Public
  
  Jackson labStock No. 014141
  
  DOI: 10.1016/j.celrep.2026.117791
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @nmaralla
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
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  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

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sciencedirect.com/science/article/pii/S2211124726008697
Jun 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neuronal AMPK regulates microglial lipid droplet accumulation in tauopathy brain

1
1. scibot 25 Jun 2026
  
  in Public
  
  Jackson Laboratory Cat_014141
  
  DOI: 10.1016/j.cmet.2024.03.014
  
  Resource: RRID:IMSR_JAX:014141
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:014141
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RRIDCUR:Unresolved

RRID:IMSR_JAX:014141

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11153007/
Oct 2025
www.sciencedirect.com www.sciencedirect.com

AMPKα2 signals amino acid insufficiency to inhibit protein synthesis

1
1. scibot 08 Oct 2025
  
  in Public
  
  Jackson LaboratoryJAX #014141
  
  DOI: 10.1016/j.cmet.2025.09.004
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S1550413125003894
Feb 2025
52.53.155.43 52.53.155.43

PDF-html.html

1
1. scibot 07 Feb 2025
  
  in Public
  
  JAX:014141
  
  DOI: 10.1101/2025.01.31.635920
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
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  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

52.53.155.43/a51f91a6f157dfac8421669b0e4c1a1a4debce17/PDF-html.html
Dec 2024
www.nature.com www.nature.com

Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing

1
1. scibot 21 Dec 2024
  
  in Public
  
  014141
  
  DOI: 10.1038/s41586-024-08348-2
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
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  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

nature.com/articles/s41586-024-08348-2
www.nature.com www.nature.com

Lithocholic acid phenocopies anti-ageing effects of calorie restriction

1
1. scibot 21 Dec 2024
  
  in Public
  
  014141
  
  DOI: 10.1038/s41586-024-08329-5
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

nature.com/articles/s41586-024-08329-5
Jan 2023
www.sciencedirect.com www.sciencedirect.com

Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

1
1. scibot 24 Jan 2023
  
  in Public
  
  RRID:IMSR_JAX:014141
  
  DOI: 10.1016/j.celrep.2023.112035
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S2211124723000463
Jul 2022
www.sciencedirect.com www.sciencedirect.com

PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis

1
1. scibot 27 Jul 2022
  
  in Public
  
  JAX# 014141
  
  DOI: 10.1016/j.celrep.2022.111125
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722009317
Jan 2022
www.sciencedirect.com www.sciencedirect.com

Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling

1
1. scibot 26 Jan 2022
  
  in Public
  
  #014141, Jackson Lab
  
  DOI: 10.1016/j.ebiom.2022.103842
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S2352396422000263
Dec 2021
www.sciencedirect.com www.sciencedirect.com

AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells

1
1. scibot 21 Dec 2021
  
  in Public
  
  JAX:014141
  
  DOI: 10.1016/j.isci.2021.103570
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S2589004221015406
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 28 Jul 2021
  
  in Public
  
  STOCK Prkaa1tm1.1Sjm/J
  
  DOI: 10.1016/j.celrep.2019.05.020
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S221112471930631X
Sep 2020
www.sciencedirect.com www.sciencedirect.com

A Metformin-Responsive Metabolic Pathway Controls Distinct Steps in Gastric Progenitor Fate Decisions and Maturation

1
1. scibot 07 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:014141
  
  DOI: 10.1016/j.stem.2020.03.006
  
  Resource: (IMSR Cat# JAX_014141,RRID:IMSR_JAX:014141)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:014141
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RRIDCUR:Validated

RRID:IMSR_JAX:014141

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590920300989
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice

1
1. scibot 08 Nov 2017
  
  in Public
  
  014141
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:014141
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:014141 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:014141

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scibot

URL

sciencedirect.com/science/article/pii/S1550413117302152
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:014141
  
  Resource used:
  
  RRID:IMSR_JAX:014141
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:014141
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RRID:IMSR_JAX:014141

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC5501726/table/undtbl1/
www.sciencedirect.com www.sciencedirect.com

Hypothalamic AMPK-ER Stress-JNK1 Axis Mediates the Central Actions of Thyroid Hormones on Energy Balance

1
1. scibot 08 Nov 2017
  
  in Public
  
  IMSR_JAX:014141
  
  Curator: @chewbeccax
  
  Resource used:
  
  RRID:IMSR_JAX:014141
  
  SciCrunch record: RRID:IMSR_JAX:014141
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:014141 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:014141

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S155041311730356X