Hypothesis

13 Matching Annotations

Feb 2026
www.sciencedirect.com www.sciencedirect.com

Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis

1
1. scibot 12 Feb 2026
  
  in Public
  
  JAX:017573
  
  DOI: 10.1016/j.chembiol.2026.01.006
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

sciencedirect.com/science/article/pii/S2451945626000267
Mar 2025
www.sciencedirect.com www.sciencedirect.com

A niche driven mechanism determines response and a mutation-independent therapeutic approach for myeloid malignancies

1
1. scibot 28 Mar 2025
  
  in Public
  
  JAX: 017573
  
  DOI: 10.1016/j.ccell.2025.03.007
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

sciencedirect.com/science/article/pii/S1535610825001084
Jan 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Ascorbate deficiency increases quiescence and self-renewal in hematopoietic stem cells and multipotent progenitors

1
1. scibot 25 Jan 2025
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1182/blood.2024024769
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11738029/
Oct 2023
52.53.155.43 52.53.155.43

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

1
1. scibot 20 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1101/2023.09.04.556230
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

52.53.155.43/7552772d6831058dd86904edd1d771977789c7d8/2023.09.04.556230.full-html.html
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function

1
1. scibot 10 Nov 2022
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1016/j.celrep.2022.111612
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722014814
Oct 2021
www.sciencedirect.com www.sciencedirect.com

Proinflammatory cytokines promote TET2-mediated DNA demethylation during CD8 T cell effector differentiation

1
1. scibot 13 Oct 2021
  
  in Public
  
  Cat#017573
  
  DOI: 10.1016/j.celrep.2021.109796
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124721012560
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Deterministic Somatic Cell Reprogramming Involves Continuous Transcriptional Changes Governed by Myc and Epigenetic-Driven Modules

1
1. scibot 10 Aug 2021
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1016/j.stem.2018.11.014
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

sciencedirect.com/science/article/pii/S1934590918305502
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1016/j.stem.2018.08.016
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590918304016
www.sciencedirect.com www.sciencedirect.com

TET2 Regulates the Neuroinflammatory Response in Microglia

1
1. scibot 29 Jul 2021
  
  in Public
  
  The Jackson LaboratoryCat.# 017573
  
  DOI: 10.1016/j.celrep.2019.09.013
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719311908
Jun 2021
www.nature.com www.nature.com

TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice

1
1. scibot 12 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  DOI: 10.1038/s41467-021-23735-3
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

nature.com/articles/s41467-021-23735-3
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

DNMT1 in Six2 Progenitor Cells Is Essential for Transposable Element Silencing and Kidney Development

1
1. scibot 18 Nov 2020
  
  in Public
  
  017573
  
  DOI: 10.1681/ASN.2018070687
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573
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RRID:IMSR_JAX:017573

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6442333/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms

1
1. scibot 04 Sep 2020
  
  in Public
  
  Tet2fl/fl (B6;129S-Tet2tm1.1Iaai/J)
  
  DOI: 10.1016/j.celrep.2020.02.056
  
  Resource: (IMSR Cat# JAX_017573,RRID:IMSR_JAX:017573)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  What is this?
  
  RRID:IMSR_JAX:017573 RRIDCUR:Missing
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RRID:IMSR_JAX:017573

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720302242
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:IMSR_JAX:017573
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:017573
  
  SciCrunch record: RRID:IMSR_JAX:017573
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:017573 RRIDCUR:Validated
Visit annotations in context

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RRID:IMSR_JAX:017573

RRIDCUR:Validated

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761317303278