Hypothesis

19 Matching Annotations

Apr 2026
www.biorxiv.org www.biorxiv.org

Heterogeneous pro-inflammatory response to BRAFV600E-induced thyroid tumor development

1
1. scibot 03 Apr 2026
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.64898/2026.03.26.714444
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

biorxiv.org/content/10.64898/2026.03.26.714444v1
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

BRAFV600E Expression in c-Kit+ Interstitial Cells of Cajal Drives Gastrointestinal Stromal Tumor Formation in Mice

1
1. scibot 26 Mar 2026
  
  in Public
  
  JAX:017837
  
  DOI: 10.1158/2767-9764.CRC-25-0725
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC13012002/
www.biorxiv.org www.biorxiv.org

Resolving thyroid lineage cell trajectories merging into a dual endocrine gland in mammals

1
1. scibot 19 Mar 2026
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.64898/2026.03.11.710917
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

biorxiv.org/content/10.64898/2026.03.11.710917v1
Nov 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Functional mapping of epigenomic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes

1
1. scibot 23 Nov 2025
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1158/2159-8290.CD-24-1565
  
  Resource: None
  
  Curator: @olekpark
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRIDCUR:Unresolved RRIDCUR:Incorrect RRID:IMSR_JAX:017837
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RRIDCUR:Incorrect

RRID:IMSR_JAX:017837

RRIDCUR:Unresolved

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC12469823/
www.sciencedirect.com www.sciencedirect.com

Fosl1 is a transcriptional effector of BRAFV600E-driven intestinal tumorigenesis

1
1. scibot 15 Nov 2025
  
  in Public
  
  Jackson Stock Number: 017837
  
  DOI: 10.1016/j.isci.2025.113875
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

sciencedirect.com/science/article/pii/S2589004225021364
Jun 2025
www.sciencedirect.com www.sciencedirect.com

BRAF/MEK inhibition induces cell state transitions boosting immune checkpoint sensitivity in BRAFV600E-mutant glioma

1
1. scibot 13 Jun 2025
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1016/j.xcrm.2025.102183
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

sciencedirect.com/science/article/pii/S2666379125002563
Mar 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor Cell Plasticity and Stromal Microenvironment Distinguish Papillary and Follicular Growth Patterns in a Mouse Model of BRAFV600E-Induced Thyroid Cancer

1
1. scibot 13 Mar 2025
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1158/2767-9764.CRC-24-0474
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11885905/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

FAK loss reduces BRAFV600E-induced ERK phosphorylation to promote intestinal stemness and cecal tumor formation

1
1. scibot 14 Nov 2024
  
  in Public
  
  017837
  
  DOI: 10.21203/rs.3.rs-2531119/v2
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC9915899/
Aug 2024
www.researchsquare.com www.researchsquare.com

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1
1. scibot 02 Aug 2024
  
  in Public
  
  017837
  
  DOI: 10.21203/rs.3.rs-2531119/v1
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

researchsquare.com/
Jun 2024
www.mdpi.com www.mdpi.com

Single-Cell Profiling Reveals the Impact of Genetic Alterations on the Differentiation of Inflammation-Induced Murine Colon Tumors

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.3390/cancers16112040
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

mdpi.com/2072-6694/16/11/2040
Feb 2024
www.biorxiv.org www.biorxiv.org

Single-cell profiling reveals the impact of genetic alterations on the differentiation of inflammation-induced colon tumors

1
1. scibot 09 Feb 2024
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1101/2023.11.30.569463
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

biorxiv.org/content/10.1101/2023.11.30.569463v1
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders

1
1. scibot 17 Dec 2023
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1016/j.immuni.2023.11.011
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

sciencedirect.com/science/article/pii/S1074761323004934
Jul 2023
www.sciencedirect.com www.sciencedirect.com

Tissue specificity of oncogenic BRAF targeted to lung and thyroid through a shared lineage factor

1
1. scibot 01 Jul 2023
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1016/j.isci.2023.107071
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
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  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

sciencedirect.com/science/article/pii/S2589004223011483
Mar 2023
www.nature.com www.nature.com

Multiplexed screens identify RAS paralogues HRAS and NRAS as suppressors of KRAS-driven lung cancer growth

1
1. scibot 01 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1038/s41556-022-01049-w
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @a5munoz
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

RRIDCUR:Unresolved

Annotators

scibot

URL

nature.com/articles/s41556-022-01049-w
Dec 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transposon Mutagenesis Reveals RBMS3 Silencing as a Promoter of Malignant Progression of BRAFV600E-Driven Lung Tumorigenesis

1
1. scibot 30 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1158/0008-5472.CAN-21-3214
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9664136/
Jan 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Bacterial-driven inflammation and mutant BRAF expression combine to promote murine colon tumorigenesis that is sensitive to immune checkpoint therapy

1
1. scibot 03 Jan 2022
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1158/2159-8290.CD-20-0770
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837
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RRID:IMSR_JAX:017837

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8295175/
Dec 2020
www.cell.com www.cell.com

Wnt-Dependent Oligodendroglial-Endothelial Interactions Regulate White Matter Vascularization and Attenuate Injury

1
1. scibot 11 Dec 2020
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.1016/j.neuron.2020.09.033
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:017837
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RRIDCUR:Validated

RRID:IMSR_JAX:017837

Annotators

scibot

URL

cell.com/neuron/abstract/S0896-6273(20)30757-1
Jan 2020
elifesciences.org elifesciences.org

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  DOI: 10.7554/eLife.43668
  
  Resource: (IMSR Cat# JAX_017837,RRID:IMSR_JAX:017837)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  What is this?
  
  RRID:IMSR_JAX:017837 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:017837

Annotators

scibot

URL

elifesciences.org/articles/43668
Nov 2018
www.sciencedirect.com www.sciencedirect.com

EZH2-Mediated Primary Cilium Deconstruction Drives Metastatic Melanoma Formation

1
1. scibot 05 Nov 2018
  
  in Public
  
  RRID:IMSR_JAX:017837
  
  Curator: @anp055
  
  Resource used:
  
  RRID:IMSR_JAX:017837
  
  SciCrunch record: RRID:IMSR_JAX:017837
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:017837 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:IMSR_JAX:017837

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610818302290