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Microglia prune developing cortical blood vessels through PD-1 signaling

1
1. scibot 21 Jul 2026
  
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  025524
  
  DOI: 10.1038/s41593-026-02378-x
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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nature.com/articles/s41593-026-02378-x
Jul 2026
54.241.53.176 54.241.53.176

Microglial CD31 suppresses Aβ clearance and promotes Alzheimer pathology in 5×FAD mice

1
1. scibot 07 Jul 2026
  
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  JAX:025524
  
  DOI: 10.1038/s41467-026-74037-5
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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54.241.53.176/4a8327e0de8e863ad0505c87e648ca5413ae5f50/s41467-026-74037-5_reference-html.html
Jun 2026
www.sciencedirect.com www.sciencedirect.com

Decoding the spatiotemporal development of human meninges

1
1. scibot 03 Jun 2026
  
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  Jackson LaboratoryStock No: 025524
  
  DOI: 10.1016/j.cell.2026.04.040
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @nmaralla
  
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sciencedirect.com/science/article/pii/S0092867426005076
Apr 2026
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Numb attenuates LPS-induced neuroinflammation via autophagic regulation of Ifi204 in microglia

1
1. scibot 09 Apr 2026
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.nbd.2026.107386
  
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sciencedirect.com/science/article/pii/S0969996126001312
Mar 2026
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High-fat diet causes rapid loss of intestinal group 3 innate lymphoid cells through microbiota-driven inflammation and mitochondrial stress

1
1. scibot 31 Mar 2026
  
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  Jackson LaboratoryStrain #025524
  
  DOI: 10.1016/j.immuni.2026.02.014
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S1074761326000841
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Mitochondrial transfer to granulocytic myeloid-derived suppressor cells augments immunosuppressive activity

1
1. scibot 17 Mar 2026
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.celrep.2026.117057
  
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sciencedirect.com/science/article/pii/S221112472600135X
Jan 2026
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Ferroplasticity drives social isolation-induced anxiety via a ventral hippocampal iron-α-synuclein axis

1
1. scibot 29 Jan 2026
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.cmet.2025.12.022
  
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sciencedirect.com/science/article/pii/S1550413125005868
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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder

1
1. scibot 23 Jan 2026
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.cell.2025.12.012
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0092867425014254
54.241.53.176 54.241.53.176

1-s2.0-S2589004226000933-main-html.html

1
1. scibot 22 Jan 2026
  
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  JAX:025524
  
  DOI: 10.1016/j.isci.2026.114718
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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54.241.53.176/274ace912c8b587ab9fd6559c3788da7dc689c70/1-s2.0-S2589004226000933-main-html.html
advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

1
1. scibot 06 Jan 2026
  
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  025524
  
  DOI: 10.1002/advs.202515138
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @dhovakimyan1
  
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advanced.onlinelibrary.wiley.com/doi/full/10.1002/advs.202515138
Oct 2025
54.241.53.176 54.241.53.176

1-s2.0-S2589004225020565-main-html.html

1
1. scibot 18 Oct 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.isci.2025.113795
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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54.241.53.176/11bcb8308dde8f6a85e5c6e2efbb0eabd0db7327/1-s2.0-S2589004225020565-main-html.html
Sep 2025
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Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface

1
1. scibot 11 Sep 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.devcel.2025.08.012
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S1534580725005325
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Innate immune sensing of Z-nucleic acids by ZBP1-RIPK1 axis drives neuroinflammation in Alzheimer’s disease

1
1. scibot 03 Sep 2025
  
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  Jackson Laboratory Cat_025524
  
  DOI: 10.1016/j.immuni.2025.07.024
  
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  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:025524
  
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  RRID:IMSR_JAX:025524 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S1074761325003334
Aug 2025
www.nature.com www.nature.com

NADPH acts as an endogenous P2X7 receptor modulator to gate neuroinflammatory responses of microglia

1
1. scibot 14 Aug 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1038/s41401-025-01638-z
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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nature.com/articles/s41401-025-01638-z
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Microglia mediated by LAG3 regulate astrocyte morphogenesis in the brain white matter

1
1. scibot 07 Aug 2025
  
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  JAX:025524
  
  DOI: 10.1016/j.celrep.2025.116112
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S2211124725008836
Jul 2025
www.cell.com www.cell.com

G-protein-coupled receptor ADGRG1 drives a protective microglial state in Alzheimer's disease through MYC activation

1
1. scibot 29 Jul 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.neuron.2025.06.020
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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cell.com/neuron/fulltext/S0896-6273(25)00478-7
May 2025
www.sciencedirect.com www.sciencedirect.com

Inflammasome signaling in astrocytes modulates hippocampal plasticity

1
1. scibot 17 May 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2025.04.007
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S1074761325001700
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IL-10 sensing by lung interstitial macrophages prevents bacterial dysbiosis-driven pulmonary inflammation and maintains immune homeostasis

1
1. scibot 17 May 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2025.04.004
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S1074761325001670
link.springer.com link.springer.com

Acute and Long-Term Consequences of Neonatal NMDA Blockade in the Cx3cr1 Knock-Out Mouse

1
1. scibot 16 May 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1007/s10753-025-02272-x
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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link.springer.com/article/10.1007/s10753-025-02272-x
Mar 2025
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The transcription factor MEF2C restrains microglial overactivation by inhibiting kinase CDK2

1
1. scibot 29 Mar 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2025.02.026
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761325000937
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Radial glia integrin avb8 regulates cell autonomous microglial TGFβ1 signaling that is necessary for microglial identity

1
1. scibot 27 Mar 2025
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1038/s41467-025-57684-y
  
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  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11929771/
Feb 2025
jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com

Interferon-gamma receptor signaling regulates innate immunity during Staphylococcus aureus craniotomy infection

1
1. scibot 25 Feb 2025
  
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  RRID: IMSR_JAX:025524
  
  DOI: 10.1186/s12974-025-03376-9
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @inessasarian
  
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jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-025-03376-9
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Activity-dependent regulation of microglia numbers by pyramidal cells during development shape cortical functions

1
1. scibot 23 Feb 2025
  
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  JAX:025524
  
  DOI: 10.1126/sciadv.adq5842
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11838000/
Nov 2024
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Differential contributions of fetal mononuclear phagocytes to Zika virus neuroinvasion versus neuroprotection during congenital infection

1
1. scibot 14 Nov 2024
  
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  Cat# 025524
  
  DOI: 10.1016/j.cell.2024.10.028
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @vtello
  
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  RRID:IMSR_JAX:025524
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sciencedirect.com/science/article/pii/S0092867424012108
Jul 2024
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Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs

1
1. scibot 17 Jul 2024
  
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  JAX:025524
  
  DOI: 10.1016/j.neuron.2024.06.017
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0896627324004525
Jun 2024
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The brain microvasculature is a primary mediator of interferon-α neurotoxicity in human cerebral interferonopathies

1
1. scibot 21 Jun 2024
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2024.05.017
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S1074761324002711
May 2024
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Classical monocyte ontogeny dictates their functions and fates as tissue macrophages

1
1. scibot 16 May 2024
  
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  025524
  
  DOI: 10.1016/j.immuni.2024.04.019
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @abever99
  
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sciencedirect.com/science/article/pii/S1074761324002243
Apr 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

UFObow: A single-wavelength excitable Brainbow for simultaneous multicolor ex-vivo and in-vivo imaging of mammalian cells

1
1. scibot 14 Apr 2024
  
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  JAX:025524
  
  DOI: 10.1038/s42003-024-06062-3
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10984974/
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms

1
1. scibot 06 Mar 2024
  
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  JAX025524
  
  DOI: 10.1016/j.celrep.2023.113661
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @abever99
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10851928/
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety

1
1. scibot 23 Feb 2024
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2024.01.018
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S107476132400044X
Dec 2023
www.sciencedirect.com www.sciencedirect.com

BACH1 changes microglial metabolism and affects astrogenesis during mouse brain development

1
1. scibot 16 Dec 2023
  
  in Public
  
  Jackson LaboratoryStock No: 025524
  
  DOI: 10.1016/j.devcel.2023.11.018
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S1534580723006160
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Radial glia promote microglial development through integrin αVβ8 -TGFβ1 signaling

1
1. scibot 12 Oct 2023
  
  in Public
  
  RRID:IMSR_JAX:025524
  
  DOI: 10.1101/2023.07.13.548459
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @scibot
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10542141/
May 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection

1
1. scibot 16 May 2023
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1186/s12974-023-02798-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10183138/
Feb 2023
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Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease

1
1. scibot 03 Feb 2023
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2023.01.008
  
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sciencedirect.com/science/article/pii/S1074761323000183
Jan 2023
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Chimeric efferocytic receptors improve apoptotic cell clearance and alleviate inflammation

1
1. scibot 10 Jan 2023
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.cell.2022.11.029
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0092867422015045
Aug 2022
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Apolipoprotein E4 impairs the response of neurodegenerative retinal microglia and prevents neuronal loss in glaucoma

1
1. scibot 17 Aug 2022
  
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  JAX:025524
  
  DOI: 10.1016/j.immuni.2022.07.014
  
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sciencedirect.com/science/article/pii/S1074761322003491
Mar 2022
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Macrophage network dynamics depend on haptokinesis for optimal local surveillance

1
1. scibot 31 Mar 2022
  
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  JAX:025524
  
  DOI: 10.7554/eLife.75354
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8963880/
Jan 2022
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Disruption of the IL-33-ST2-AKT signaling axis impairs neurodevelopment by inhibiting microglial metabolic adaptation and phagocytic function

1
1. scibot 04 Jan 2022
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.immuni.2021.12.001
  
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sciencedirect.com/science/article/pii/S1074761321005343
Nov 2021
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COMMD10 is critical for Kupffer cell survival and controls Ly6Chi monocyte differentiation and inflammation in the injured liver

1
1. scibot 17 Nov 2021
  
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  Stock No: 025524
  
  DOI: 10.1016/j.celrep.2021.110026
  
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sciencedirect.com/science/article/pii/S2211124721015084
Sep 2021
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Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

1
1. scibot 22 Sep 2021
  
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  JAX:025524
  
  DOI: 10.1016/j.celrep.2021.109720
  
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sciencedirect.com/science/article/pii/S2211124721011694
Aug 2021
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Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

1
1. scibot 04 Aug 2021
  
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  RRID:IMSR_JAX025524
  
  DOI: 10.1016/j.immuni.2017.05.003
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S1074761317302194
Jul 2021
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Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

1
1. scibot 29 Jul 2021
  
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  JAX 025524
  
  DOI: 10.1016/j.cell.2019.08.009
  
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sciencedirect.com/science/article/pii/S0092867419308979
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Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation

1
1. scibot 23 Jul 2021
  
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  Cat# 025524
  
  DOI: 10.1016/j.immuni.2021.06.014
  
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sciencedirect.com/science/article/pii/S1074761321002582
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GABA-receptive microglia selectively sculpt developing inhibitory circuits

1
1. scibot 07 Jul 2021
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.cell.2021.06.018
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0092867421007534
Jun 2021
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C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation

1
1. scibot 16 Jun 2021
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.neuron.2021.05.020
  
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sciencedirect.com/science/article/pii/S0896627321003731
May 2021
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Sensory Experience Engages Microglia to Shape Neural Connectivity through a Non-Phagocytic Mechanism

1
1. scibot 08 May 2021
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.neuron.2020.08.002
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0896627320306097
Apr 2021
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Microglial Remodeling of the Extracellular Matrix Promotes Synapse Plasticity

1
1. scibot 23 Apr 2021
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.cell.2020.05.050
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
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sciencedirect.com/science/article/pii/S0092867420306838
Dec 2020
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Mitochondrial Ca2+ Signaling Is an Electrometabolic Switch to Fuel Phagosome Killing

1
1. scibot 07 Dec 2020
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.1016/j.celrep.2020.108411
  
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  RRIDCUR:Validated RRID:IMSR_JAX:025524
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sciencedirect.com/science/article/pii/S2211124720314005
Nov 2020
elifesciences.org elifesciences.org

LRRC8A is essential for hypotonicity-, but not for DAMP-induced NLRP3 inflammasome activation

1
1. scibot 26 Nov 2020
  
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  RRID:IMSR_JAX:025524
  
  DOI: 10.7554/eLife.59704
  
  Resource: (IMSR Cat# JAX_025524,RRID:IMSR_JAX:025524)
  
  Curator: @evieth
  
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  RRID:IMSR_JAX:025524 RRIDCUR:Validated
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elifesciences.org/articles/59704
Apr 2019
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Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain

1
1. scibot 05 Apr 2019
  
  in Public
  
  IMSR_JAX025524
  
  Curator: @chewbeccax
  
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  SciCrunch record: RRID:IMSR_JAX025524
  
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  RRID:IMSR_JAX:025524 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761317302194