Hypothesis

15 Matching Annotations

May 2025
www.sciencedirect.com www.sciencedirect.com

Targeting WEE1 in tumor-associated dendritic cells potentiates antitumor immunity via the cGAS/STING pathway

1
1. scibot 22 May 2025
  
  in Public
  
  Jackson LaboratoryCat# 025805
  
  DOI: 10.1016/j.celrep.2025.115733
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S2211124725005042
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Nanoparticle delivery of innate immune agonists combined with senescence-inducing agents promotes T cell control of pancreatic cancer

1
1. scibot 13 Feb 2025
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1126/scitranslmed.adj9366
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11811823/
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Increased levels of endogenous retroviruses trigger fibroinflammation and play a role in kidney disease development

1
1. scibot 14 Nov 2024
  
  in Public
  
  025805
  
  DOI: 10.1038/s41467-023-36212-w
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC9895454/
May 2024
www.sciencedirect.com www.sciencedirect.com

Development of nitroalkene-based inhibitors to target STING-dependent inflammation

1
1. scibot 23 May 2024
  
  in Public
  
  JAX:025805
  
  DOI: 10.1016/j.redox.2024.103202
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S2213231724001800
www.sciencedirect.com www.sciencedirect.com

Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint

1
1. scibot 21 May 2024
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1016/j.celrep.2024.114209
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S2211124724005370
Dec 2022
www.sciencedirect.com www.sciencedirect.com

Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis

1
1. scibot 16 Dec 2022
  
  in Public
  
  RRID:IMSR_JAX
  
  DOI: 10.1016/j.neuron.2022.10.028
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @evieth
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805 RRIDCUR:Unresolved
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RRID:IMSR_JAX:025805

RRIDCUR:Unresolved

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0896627322009618
Sep 2022
www.nature.com www.nature.com

Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair

1
1. scibot 21 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1038/s41423-022-00919-5
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

nature.com/articles/s41423-022-00919-5
Nov 2021
www.sciencedirect.com www.sciencedirect.com

APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis

1
1. scibot 09 Nov 2021
  
  in Public
  
  Stock#025805
  
  DOI: 10.1016/j.immuni.2021.10.004
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761321004106
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Mitochondrial Damage and Activation of the STING Pathway Lead to Renal Inflammation and Fibrosis

1
1. scibot 29 Jul 2021
  
  in Public
  
  Jackson LaboratoryCat#025805
  
  DOI: 10.1016/j.cmet.2019.08.003
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805 RRIDCUR:Unrecognized
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RRID:IMSR_JAX:025805

RRIDCUR:Unrecognized

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1550413119304322
Jun 2021
www.cell.com www.cell.com

Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

1
1. scibot 24 Jun 2021
  
  in Public
  
  Jax 025805
  
  DOI: 10.1016/j.cell.2021.05.020
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805 RRIDCUR:Missing
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RRID:IMSR_JAX:025805

RRIDCUR:Missing

Annotators

scibot

URL

cell.com/cell/fulltext/S0092-8674(21)00650-4
www.sciencedirect.com www.sciencedirect.com

Cytomegalovirus subverts macrophage identity

1
1. scibot 11 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1016/j.cell.2021.05.009
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S0092867421006267
www.sciencedirect.com www.sciencedirect.com

Type I interferon decreases macrophage energy metabolism during mycobacterial infection

1
1. scibot 02 Jun 2021
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1016/j.celrep.2021.109195
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721005416
May 2021
www.sciencedirect.com www.sciencedirect.com

The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

1
1. scibot 12 May 2021
  
  in Public
  
  RRID:IMSR_JAX:025805
  
  DOI: 10.1016/j.immuni.2021.04.019
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  What is this?
  
  RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

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scibot

URL

sciencedirect.com/science/article/pii/S1074761321001813
Oct 2020
www.sciencedirect.com www.sciencedirect.com

Pairwise Stimulations of Pathogen-Sensing Pathways Predict Immune Responses to Multi-adjuvant Combinations

1
1. scibot 31 Oct 2020
  
  in Public
  
  B6(Cg)-Sting1tm1.2Camb/J
  
  DOI: 10.1016/j.cels.2020.10.001
  
  Resource: (IMSR Cat# JAX_025805,RRID:IMSR_JAX:025805)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  Curator comments: B6(Cg)-Sting1tm1.2Camb/J Mus musculus IMSR Cat# JAX:025805
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:025805
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RRID:IMSR_JAX:025805

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2405471220303690
Nov 2017
www.sciencedirect.com www.sciencedirect.com

The Hippo Pathway Kinases LATS1/2 Suppress Cancer Immunity

1
1. scibot 08 Nov 2017
  
  in Public
  
  JAX: 025805
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:025805
  
  SciCrunch record: RRID:IMSR_JAX:025805
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:025805 RRIDCUR:Missing
Visit annotations in context

Tags

RRID:IMSR_JAX:025805

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867416315264