70 Matching Annotations
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    Shengxian decoction suppresses malignant progression of lung adenocarcinoma by enhancing CD8+ T cell function via the FYN-PI3K/AKT axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13335393/
  3. Jun 2026
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    Expansion and CAR engineering of granulocyte-monocyte progenitors for cellular immunotherapy
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    2026.06.09.731172.full-html.html
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    Somatic CRISPR editing of Msh3 mitigates Huntington’s disease pathology in mice
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    biorxiv.org/content/10.64898/2026.06.08.730940v1
  7. May 2026
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    A blood-brain barrier-like vascular gate limits immunotherapy efficacy in neuroendocrine cancers
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    Defining a Midgestational Window for In Utero Genome Editing of the Fetal Murine Cortex
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  10. Apr 2026
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    Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity
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    Mapping breast cancer lineage in radiation and immunotherapy using the REMAP mouse
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    biorxiv.org/content/10.64898/2026.04.15.718689v1
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    KAT6A and KAT7 Histone Acetyltransferase Complexes Are Molecular Dependencies and Therapeutic Targets in NUP98-Rearranged Acute Myeloid Leukemia
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  14. Mar 2026
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    Tissue and CD4 T cell subset dependence on the amino acid transporter SLC38A1
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  16. Feb 2026
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    Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors
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    Effector differentiation by stem-like intraepithelial γδ T cells is required for host defense against infection
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    Glomerular basement membrane structural integrity dictates trans-tissue deposition of laminin in the kidney
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    Metabolic control of innate immune activation in TET2-mutant clonal hematopoiesis
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    DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance
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  22. Jan 2026
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    TCF1lo CD8 T cells proliferate and persist autonomously in tumors
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  24. Sep 2025
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    IGF2BP3 redirects glycolytic flux to promote one-carbon metabolism and RNA methylation
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    Spatially patterned kidney assembloids recapitulate progenitor self-assembly and enable high-fidelity in vivo disease modeling
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  27. Jul 2025
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    Cognate interaction-dependent pathogenicity of meningeal B cells drives neuroinflammation relapse
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  29. Jun 2025
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    Gene-regulatory programs that specify age-related differences during thymocyte development
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    CLNS1A regulates genome stability and cell cycle progression to control CD4 T cell function and autoimmunity
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    SETDB1 promotes mammalian liver regeneration by stimulating cytokine CSF3 in hepatocytes
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  33. Feb 2025
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    In vivo engineering of murine T cells using the evolved adeno-associated virus variant Ark313
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  35. Jan 2025
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    Massively parallel reporter assay investigates shared genetic variants of eight psychiatric disorders
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    Obesity reshapes regulatory T cells in the visceral adipose tissue by disrupting cellular cholesterol homeostasis
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  38. Dec 2024
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    A pan-family screen of nuclear receptors in immunocytes reveals ligand-dependent inflammasome control
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  40. Nov 2024
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    Single-cell RNA sequencing reveals immune microenvironment niche transitions during the invasive and metastatic processes of ground-glass nodules and part-solid nodules in lung adenocarcinoma
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    A platform of functional studies of ESCC-associated gene mutations identifies the roles of TGFBR2 in ESCC progression and metastasis
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    Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation
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  44. Sep 2024
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    Impact of KDM6B mosaic brain knockout on synaptic function and behavior
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  46. Jun 2024
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    Localized translation and sarcomere maintenance requires ribosomal protein SA in mice
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  48. May 2024
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    Long-term expandable mouse and human-induced nephron progenitor cells enable kidney organoid maturation and modeling of plasticity and disease
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  50. Apr 2024
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    Crym-positive striatal astrocytes gate perseverative behaviour
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  52. Mar 2024
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    In vivo CRISPR screening directly targeting testicular cells
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  54. Jan 2024
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    Type 2 cytokine signaling in macrophages protects from cellular senescence and organismal aging
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  57. Aug 2023
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    Use of CRISPR/CAS9 Technologies to Study the Role of TLR in Dendritic Cell Subsets
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  59. Jun 2023
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    A New Type of Endometrial Cancer Models in Mice Revealing the Functional Roles of Genetic Drivers and Exploring their Susceptibilities
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  61. May 2023
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    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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  63. Jan 2023
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    An evolved AAV variant enables efficient genetic engineering of murine T cells
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  65. Nov 2022
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    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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  67. Sep 2022
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    Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
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    Excitatory SST neurons in the medial paralemniscal nucleus control repetitive self-grooming and encode reward
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  70. Jun 2022
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    Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence
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    Indoleamine 2,3-dioxygenase 1 activation in mature cDC1 promotes tolerogenic education of inflammatory cDC2 via metabolic communication
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  73. May 2022
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    A versatile viral toolkit for functional discovery in the nervous system
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  75. Apr 2022
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    Identifying a confused cell identity for esophageal squamous cell carcinoma
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    The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function
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  78. Mar 2022
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    CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
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    The megakaryocytic transcription factor ARID3A suppresses leukemia pathogenesis: Running Title: ARID3A suppresses leukemogenesis
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  81. Oct 2021
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    Costimulation molecules differentially regulate the ERK-Zfp831 axis to shape T follicular helper cell differentiation
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  83. Sep 2021
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    Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia
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  85. Aug 2021
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    ZMYND8-regulated IRF8 transcription axis is an acute myeloid leukemia dependency
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  87. Jul 2021
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    Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration
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    Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease
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    Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity
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  92. May 2021
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    High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity
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  94. Apr 2021
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    Niche-Selective Inhibition of Pathogenic Th17 Cells by Targeting Metabolic Redundancy
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    In vivo CRISPR screening reveals nutrient signaling processes underpinning CD8+ T cell fate decisions
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  97. Feb 2021
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer
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  99. Sep 2020
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    Genome-wide In Vivo CNS Screening Identifies Genes that Modify CNS Neuronal Survival and mHTT Toxicity
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    Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3
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  102. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    Neuronally Enriched RUFY3 Is Required for Caspase-Mediated Axon Degeneration
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  106. Nov 2017
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    Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons
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