Hypothesis

18 Matching Annotations

Last 7 days
www.biorxiv.org www.biorxiv.org

Cyp7b1-inhibiting azoles as novel enhancers of hematopoietic stem and progenitor cell mobilization

1
1. scibot 21 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1101/2025.10.13.682145
  
  Resource: RRID:IMSR_JAX:026622
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

biorxiv.org/content/10.1101/2025.10.13.682145v1
Sep 2025
www.sciencedirect.com www.sciencedirect.com

Multiplex base editing of BCL11A regulatory elements to treat sickle cell disease

1
1. scibot 27 Sep 2025
  
  in Public
  
  Jackson Laboratory Cat_026622
  
  DOI: 10.1016/j.xcrm.2025.102376
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622 RRIDCUR:Unresolved
Visit annotations in context

Tags

RRIDCUR:Unresolved

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2666379125004495
Aug 2025
www.tandfonline.com www.tandfonline.com

Patient-derived ovarian cancer models demonstrate the influence of tumor-associated macrophages on therapeutic response

1
1. scibot 05 Aug 2025
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1080/2162402X.2025.2537710
  
  Resource: RRID:IMSR_JAX:026622
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

tandfonline.com/doi/abs/10.1080/2162402X.2025.2537710
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

cMPL-Based Purification and Depletion of Human Hematopoietic Stem Cells: Implications for Pre-Transplant Conditioning

1
1. scibot 11 Apr 2025
  
  in Public
  
  The Jackson Laboratory Cat_026622
  
  DOI: 10.1101/2024.02.24.581887
  
  Resource: None
  
  Curator: @sjvitug
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRIDCUR:Unresolved RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRIDCUR:Unresolved

RRID:IMSR_JAX:026622

Annotators

scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC10925094/
Jan 2025
www.sciencedirect.com www.sciencedirect.com

Dual α-globin-truncated erythropoietin receptor knockin restores hemoglobin production in α-thalassemia-derived erythroid cells

1
1. scibot 07 Jan 2025
  
  in Public
  
  The Jackson Laboratory026622
  
  DOI: 10.1016/j.celrep.2024.115141
  
  Resource: RRID:IMSR_JAX:026622
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S221112472401492X
Aug 2024
www.cell.com www.cell.com

ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression

1
1. scibot 02 Aug 2024
  
  in Public
  
  026622
  
  DOI: 10.1016/j.molcel.2020.11.006
  
  Resource: RRID:IMSR_JAX:026622
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:IMSR_JAX:026622

Annotators

scibot

URL

cell.com/molecular-cell/fulltext/S1097-2765(20)30784-X
Jun 2024
www.nature.com www.nature.com

A humanized mouse that mounts mature class-switched, hypermutated and neutralizing antibody responses

1
1. scibot 28 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1038/s41590-024-01880-3
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

nature.com/articles/s41590-024-01880-3
www.nature.com www.nature.com

BRD9 regulates normal human hematopoietic stem cell function and lineage differentiation

1
1. scibot 06 Jun 2024
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1038/s41418-024-01306-5
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

nature.com/articles/s41418-024-01306-5
May 2023
www.sciencedirect.com www.sciencedirect.com

Massively parallel base editing to map variant effects in human hematopoiesis

1
1. scibot 03 May 2023
  
  in Public
  
  JAX:026622
  
  DOI: 10.1016/j.cell.2023.03.035
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S009286742300332X
Mar 2023
www.sciencedirect.com www.sciencedirect.com

Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editing

1
1. scibot 23 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1016/j.cell.2023.02.027
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S0092867423001708
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Humanized Patient-derived Xenograft Models of Disseminated Ovarian Cancer Recapitulate Key Aspects of the Tumor Immune Environment within the Peritoneal Cavity

1
1. scibot 04 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1158/2767-9764.CRC-22-0300
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9973420/
Nov 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
1. scibot 05 Nov 2021
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1016/j.ebiom.2021.103646
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
May 2021
www.sciencedirect.com www.sciencedirect.com

Metabolic Regulation of Inflammasome Activity Controls Embryonic Hematopoietic Stem and Progenitor Cell Production

1
1. scibot 05 May 2021
  
  in Public
  
  JAX:026622
  
  DOI: 10.1016/j.devcel.2020.07.015
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S153458072030589X
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Preclinical evaluation for engraftment of CD34+ cells gene-edited at the sickle cell disease locus in xenograft mouse and non-human primate models

1
1. scibot 21 Apr 2021
  
  in Public
  
  026622
  
  DOI: 10.1016/j.xcrm.2021.100247
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S266637912100063X
www.sciencedirect.com www.sciencedirect.com

Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer

1
1. scibot 20 Apr 2021
  
  in Public
  
  JAX:026622
  
  DOI: 10.1016/j.molcel.2021.03.043
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRIDCUR:Validated RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1097276521002641
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Ectopic humanized mesenchymal niche in mice enables robust engraftment of myelodysplastic stem cells

1
1. scibot 28 Mar 2021
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1158/2643-3230.BCD-20-0161
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622
Visit annotations in context

Tags

RRID:IMSR_JAX:026622

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC7610449/
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Small-Molecule PAPD5 Inhibitors Restore Telomerase Activity in Patient Stem Cells

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:IMSR_JAX:026622
  
  DOI: 10.1016/j.stem.2020.03.016
  
  Resource: (IMSR Cat# JAX_026622,RRID:IMSR_JAX:026622)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  What is this?
  
  RRID:IMSR_JAX:026622 RRIDCUR:Validated
Visit annotations in context

Tags

RRIDCUR:Validated

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1934590920301387
Nov 2017
www.sciencedirect.com www.sciencedirect.com

Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia

1
1. scibot 08 Nov 2017
  
  in Public
  
  026622
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:026622
  
  SciCrunch record: RRID:IMSR_JAX:026622
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:026622 RRIDCUR:Missing
Visit annotations in context

Tags

RRIDCUR:Missing

RRID:IMSR_JAX:026622

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610817303069