Hypothesis

20 Matching Annotations

Oct 2025
www.biorxiv.org www.biorxiv.org

Toll-like Receptor 4 Contributes to PCOS-like Metabolic and Reproductive Pathogenesis

1
1. scibot 23 Oct 2025
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1101/2025.10.16.682907
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
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  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

biorxiv.org/content/10.1101/2025.10.16.682907v1
Sep 2025
www.science.org www.science.org

Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans

1
1. scibot 04 Sep 2025
  
  in Public
  
  JAX, no. 029015
  
  DOI: 10.1126/scitranslmed.adp5653
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @dhovakimyan1
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

science.org/doi/10.1126/scitranslmed.adp5653
Jul 2025
www.sciencedirect.com www.sciencedirect.com

Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
  in Public
  
  JAX:029015
  
  DOI: 10.1016/j.cell.2025.05.016
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S0092867425005665
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Stored RBC Transfusions Leads to the Systemic Inflammatory Response Syndrome in Anemic Murine Neonates

1
1. scibot 12 Nov 2024
  
  in Public
  
  029015
  
  DOI: 10.1007/s00011-024-01936-y
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @AleksanderDrozdz
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
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  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

pmc.ncbi.nlm.nih.gov/articles/PMC11540732/
Sep 2024
www.sciencedirect.com www.sciencedirect.com

Cecal necroptosis triggers lethal cardiac dysfunction in TNF-induced severe SIRS

1
1. scibot 27 Sep 2024
  
  in Public
  
  Strain # 029015
  
  DOI: 10.1016/j.celrep.2024.114778
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @vtello
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S221112472401129X
Feb 2024
www.sciencedirect.com www.sciencedirect.com

Gut complement induced by the microbiota combats pathogens and spares commensals

1
1. scibot 06 Feb 2024
  
  in Public
  
  Mouse: B6(Cg)-Tlr4tm1.2Karp/JJackson LaboratoryStock #:029015
  
  DOI: 10.1016/j.cell.2023.12.036
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @abever99
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
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  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424000011
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes

1
1. scibot 16 Mar 2023
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1158/2767-9764.CRC-22-0368
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
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  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10010194/
Sep 2022
www.sciencedirect.com www.sciencedirect.com

Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain

1
1. scibot 13 Sep 2022
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1016/j.chom.2022.08.009
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1931312822004085
May 2022
www.sciencedirect.com www.sciencedirect.com

Candida albicans oscillating UME6 expression during intestinal colonization primes systemic Th17 protective immunity

1
1. scibot 19 May 2022
  
  in Public
  
  The Jackson LaboratoryStock No: 029015
  
  DOI: 10.1016/j.celrep.2022.110837
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722006106
Apr 2022
www.sciencedirect.com www.sciencedirect.com

TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells

1
1. scibot 14 Apr 2022
  
  in Public
  
  Jackson LaboratoryStock# 029015
  
  DOI: 10.1016/j.celrep.2022.110657
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @sophiastull
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S2211124722004090
Feb 2022
www.sciencedirect.com www.sciencedirect.com

Bacterial infection disrupts established germinal center reactions through monocyte recruitment and impaired metabolic adaptation

1
1. scibot 23 Feb 2022
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1016/j.immuni.2022.01.013
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1074761322000425
Dec 2021
www.sciencedirect.com www.sciencedirect.com

GM-CSF production by non-classical monocytes controls antagonistic LPS-driven functions in allergic inflammation

1
1. scibot 29 Dec 2021
  
  in Public
  
  Stock No: 029015
  
  DOI: 10.1016/j.celrep.2021.110178
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721016788
Sep 2021
www.sciencedirect.com www.sciencedirect.com

Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
  in Public
  
  Stock#029015
  
  DOI: 10.1016/j.cmet.2021.09.002
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:029015
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1550413121004216
www.sciencedirect.com www.sciencedirect.com

Activating a collaborative innate-adaptive immune response to control metastasis

1
1. scibot 04 Sep 2021
  
  in Public
  
  Cat #029015
  
  DOI: 10.1016/j.ccell.2021.08.005
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:029015
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1535610821004451
Jul 2021
www.sciencedirect.com www.sciencedirect.com

Impaired Tumor-Necrosis-Factor-α-driven Dendritic Cell Activation Limits Lipopolysaccharide-Induced Protection from Allergic Inflammation in Infants

1
1. scibot 28 Jul 2021
  
  in Public
  
  029015
  
  DOI: 10.1016/j.immuni.2018.11.012
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRIDCUR:Missing RRID:IMSR_JAX:029015
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1074761318304941
May 2021
www.sciencedirect.com www.sciencedirect.com

Adult Neural Stem Cells Are Alerted by Systemic Inflammation through TNF-α Receptor Signaling

1
1. scibot 09 May 2021
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1016/j.stem.2020.10.016
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1934590920305105
Apr 2021
www.sciencedirect.com www.sciencedirect.com

The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis

1
1. scibot 24 Apr 2021
  
  in Public
  
  RRID:IMSR_JAX:029015
  
  DOI: 10.1016/j.cell.2020.06.029
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @scibot
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S0092867420308060
Jan 2021
www.sciencedirect.com www.sciencedirect.com

Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen

1
1. scibot 22 Jan 2021
  
  in Public
  
  JAX 029015
  
  DOI: 10.1016/j.celrep.2020.108613
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S2211124720316028
Dec 2020
www.sciencedirect.com www.sciencedirect.com

The persistence of interleukin-6 is regulated by a blood buffer system derived from dendritic cells

1
1. scibot 31 Dec 2020
  
  in Public
  
  029015
  
  DOI: 10.1016/j.immuni.2020.12.001
  
  Resource: (IMSR Cat# JAX_029015,RRID:IMSR_JAX:029015)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  What is this?
  
  RRID:IMSR_JAX:029015
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RRID:IMSR_JAX:029015

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scibot

URL

sciencedirect.com/science/article/pii/S1074761320305082
Nov 2018
www.sciencedirect.com www.sciencedirect.com

Accelerated Aging and Clearance of Host Anti-inflammatory Enzymes by Discrete Pathogens Fuels Sepsis

1
1. scibot 05 Nov 2018
  
  in Public
  
  029015
  
  Curator: @Jmenke
  
  Resource used:
  
  RRID:IMSR_JAX:029015
  
  SciCrunch record: RRID:IMSR_JAX:029015
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
  What is this?
  
  RRID:IMSR_JAX:029015 RRIDCUR:Missing
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RRIDCUR:Missing

RRID:IMSR_JAX:029015

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1931312818304955