52 Matching Annotations
  1. Last 7 days
  2. www.science.org www.science.org
    PI3Kγ inhibition circumvents inflammation and vascular leak in SARS-CoV-2 and other infections
    1
    1. scibot 16 Jul 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1126/scitranslmed.adi6887

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    science.org/doi/10.1126/scitranslmed.adi6887
  3. Jun 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice
    1
    1. scibot 21 Jun 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.ebiom.2024.105185

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    sciencedirect.com/science/article/pii/S2352396424002202
  5. May 2024
  6. journals.plos.org journals.plos.org
    SARS-CoV-2 infects cells lining the blood-retinal barrier and induces a hyperinflammatory immune response in the retina via systemic exposure
    1
    1. scibot 21 May 2024
      B6.Cg-Tg(K18-ACE2)2Prlmn/J

      DOI: 10.1371/journal.ppat.1012156

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    journals.plos.org/plospathogens/article
  7. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 infection exacerbates the cellular pathology of Parkinson’s disease in human dopaminergic neurons and a mouse model
    1
    1. scibot 16 May 2024
      JAX034860

      DOI: 10.1016/j.xcrm.2024.101570

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    sciencedirect.com/science/article/pii/S2666379124002623
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    The IRE1α-XBP1 arm of the unfolded protein response is a host factor activated in SARS-CoV-2 infection
    1
    1. scibot 23 Apr 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.bbadis.2024.167193

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    sciencedirect.com/science/article/pii/S0925443924001820
  10. Mar 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Murine alveolar macrophages rapidly accumulate intranasally administered SARS-CoV-2 Spike protein leading to neutrophil recruitment and damage
    1
    1. scibot 22 Mar 2024
      JAX:034860

      DOI: 10.7554/eLife.86764

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    ncbi.nlm.nih.gov/pmc/articles/PMC10954308/
  12. www.sciencedirect.com www.sciencedirect.com
    Type-I-interferon-responsive microglia shape cortical development and behavior
    2
    1. scibot 15 Mar 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.cell.2024.02.020

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    2. scibot 15 Mar 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.cell.2024.02.020

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    sciencedirect.com/science/article/pii/S0092867424001867
  13. Feb 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bioluminescence Imaging Reveals Enhanced SARS-CoV-2 Clearance in Mice with Combinatorial Regimens
    1
    1. scibot 18 Feb 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.isci.2024.109049

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    ncbi.nlm.nih.gov/pmc/articles/PMC10867665/
  15. www.sciencedirect.com www.sciencedirect.com
    An enhanced broad-spectrum peptide inhibits Omicron variants in vivo
    1
    1. scibot 14 Feb 2024
      The Jackson LaboratoryStrain#: 034860

      DOI: 10.1016/j.xcrm.2024.101418

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    sciencedirect.com/science/article/pii/S2666379124000417
  16. Jan 2024
  17. www.sciencedirect.com www.sciencedirect.com
    Fc-fused IL-7 provides broad antiviral effects against respiratory virus infections through IL-17A-producing pulmonary innate-like T cells
    1
    1. scibot 21 Jan 2024
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.xcrm.2023.101362

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    sciencedirect.com/science/article/pii/S2666379123005797
  18. www.sciencedirect.com www.sciencedirect.com
    Olgotrelvir, a dual inhibitor of SARS-CoV-2 Mpro and cathepsin L, as a standalone antiviral oral intervention candidate for COVID-19
    1
    1. scibot 11 Jan 2024
      Jackson laboratoryStrain #:034860

      DOI: 10.1016/j.medj.2023.12.004

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2666634023004026
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    Lung transcriptomics of K18-hACE2 mice highlights mechanisms and genes involved in the MVA-S vaccine-mediated immune response and protection against SARS-CoV-2 infection
    1
    1. scibot 22 Nov 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.antiviral.2023.105760

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    sciencedirect.com/science/article/abs/pii/S0166354223002383
  21. www.sciencedirect.com www.sciencedirect.com
    Cross-regulation of antibody responses against the SARS-CoV-2 Spike protein and commensal microbiota via molecular mimicry
    1
    1. scibot 17 Nov 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.chom.2023.10.007

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    sciencedirect.com/science/article/pii/S1931312823004110
  22. Oct 2023
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo
    1
    1. scibot 18 Oct 2023
      Stock # 034860

      DOI: 10.1101/2023.09.26.559550

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    ncbi.nlm.nih.gov/pmc/articles/PMC10557691/
  24. Aug 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells
    1
    1. scibot 16 Aug 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.chembiol.2023.07.011

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    sciencedirect.com/science/article/pii/S2451945623002398
  26. Jul 2023
  27. 52.53.155.43 52.53.155.43
    Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice
    1
    1. scibot 18 Jul 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1101/2023.05.31.543159

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    52.53.155.43/3122d005cdf8bbe9c1e1f743a4779437bd44eed7/2023.05.31.543159v1.full-html.html
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants
    1
    1. scibot 08 Jul 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.isci.2023.107085

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    ncbi.nlm.nih.gov/pmc/articles/PMC10251734/
  29. May 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Viral E protein neutralizes BET protein-mediated post-entry antagonism of SARS-CoV-2
    1
    1. scibot 05 May 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.celrep.2022.111088

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    sciencedirect.com/science/article/pii/S2211124722008907
  31. Mar 2023
  32. www.embopress.org www.embopress.org
    Interferon-induced transmembrane protein 3 (IFITM3) limits lethality of SARS-CoV-2 in mice
    1
    1. scibot 18 Mar 2023
      RRID:IMSR_JAX:034860

      DOI: 10.15252/embr.202256660

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    embopress.org/doi/10.15252/embr.202256660
  33. Feb 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2
    1
    1. scibot 17 Feb 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.isci.2023.106126

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    sciencedirect.com/science/article/pii/S2589004223002031
  35. Jan 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 variants induce distinct disease and impact in the bone marrow and thymus of mice
    1
    1. scibot 27 Jan 2023
      JAX:034860

      DOI: 10.1016/j.isci.2023.105972

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838028/
  37. www.mdpi.com www.mdpi.com
    Pharmacokinetic and Pharmacodynamic Effects of Polyclonal Antibodies against SARS-CoV2 in Mice
    1
    1. scibot 19 Jan 2023
      RRID:IMSR_JAX:034860

      DOI: 10.3390/v15010123

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    mdpi.com/1999-4915/15/1/123
  38. www.nature.com www.nature.com
    Full protection from SARS-CoV-2 brain infection and damage in susceptible transgenic mice conferred by MVA-CoV2-S vaccine candidate
    1
    1. scibot 12 Jan 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1038/s41593-022-01242-y

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    nature.com/articles/s41593-022-01242-y
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
    1
    1. scibot 06 Jan 2023
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.xcrm.2022.100893

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    ncbi.nlm.nih.gov/pmc/articles/PMC9799175/
  40. Nov 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced virulence and waning vaccine-elicited antibodies account for breakthrough infections caused by SARS-CoV-2 delta and beyond
    1
    1. scibot 19 Nov 2022
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.isci.2022.105507

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    ncbi.nlm.nih.gov/pmc/articles/PMC9635945/
  42. Sep 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Mucosal plasma cells are required to protect the upper airway and brain from infection
    1
    1. scibot 23 Sep 2022
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.immuni.2022.08.017

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    sciencedirect.com/science/article/pii/S1074761322004113
  44. www.sciencedirect.com www.sciencedirect.com
    Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants
    1
    1. scibot 01 Sep 2022
      Jackson laboratoryStrain #:034860

      DOI: 10.1016/j.medj.2022.08.002

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    sciencedirect.com/science/article/pii/S266663402200321X
  45. Jun 2022
  46. www.sciencedirect.com www.sciencedirect.com
    Viral infection engenders bona fide and bystander subsets of lung-resident memory B cells through a permissive mechanism
    1
    1. scibot 30 Jun 2022
      The Jackson LaboratoryStrain code: 034860

      DOI: 10.1016/j.immuni.2022.06.002

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    sciencedirect.com/science/article/pii/S1074761322002400
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VE607 Stabilizes SARS-CoV-2 Spike In the “RBD-up” Conformation and Inhibits Viral Entry
    1
    1. scibot 24 Jun 2022
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.isci.2022.104528

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    ncbi.nlm.nih.gov/pmc/articles/PMC9164512/
  48. May 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Nasally-delivered interferon-λ protects mice against infection by SARS-CoV-2 variants including Omicron
    1
    1. scibot 06 May 2022
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.celrep.2022.110799

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    sciencedirect.com/science/article/pii/S2211124722005666
  50. Mar 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A type I interferon response defines a conserved microglial state required for effective neuronal phagocytosis
    1
    1. scibot 09 Mar 2022
      JAX#034860

      DOI: 10.1101/2021.04.29.441889

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    ncbi.nlm.nih.gov/pmc/articles/PMC8887080/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
    1
    1. scibot 04 Mar 2022
      RRID:ISMR_JAX:034860

      DOI: 10.1016/j.cell.2022.02.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC8825346/
  53. Feb 2022
  54. www.sciencedirect.com www.sciencedirect.com
    SARS-CoV-2 variants of concern display enhanced intrinsic pathogenic properties and expanded organ tropism in mouse models
    2
    1. scibot 11 Feb 2022
      034860

      DOI: 10.1016/j.celrep.2022.110387

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    2. scibot 09 Feb 2022
      034860

      DOI: 10.1016/j.celrep.2022.110387

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    sciencedirect.com/science/article/pii/S2211124722001085
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection
    1
    1. scibot 08 Feb 2022
      RRID:IMSR_JAX

      DOI: 10.1016/j.celrep.2022.110368

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    ncbi.nlm.nih.gov/pmc/articles/PMC8786652/
  56. Jan 2022
  57. www.sciencedirect.com www.sciencedirect.com
    Acriflavine, a clinically approved drug, inhibits SARS-CoV-2 and other betacoronaviruses
    1
    1. scibot 12 Jan 2022
      The Jackson LaboratoryStock no.: 034860

      DOI: 10.1016/j.chembiol.2021.11.006

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    sciencedirect.com/science/article/pii/S2451945621005134
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
    1
    1. scibot 05 Jan 2022
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.celrep.2021.110210

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC8673750/
  59. Nov 2021
  60. www.sciencedirect.com www.sciencedirect.com
    Beta RBD Boost Broadens Antibody-Mediated Protection Against SARS-CoV-2 Variants in Animal Models
    1
    1. scibot 18 Nov 2021
      RRID:MSR_JAX:034860

      DOI: 10.1016/j.xcrm.2021.100450

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:034860

      Curator comments: B6.Cg-Tg(K18-ACE2)2Prlmn/J Mus musculus IMSR Cat# JAX:034860

      What is this?
      RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:IMSR_JAX:034860
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    sciencedirect.com/science/article/pii/S2666379121003189
  61. Sep 2021
  62. www.sciencedirect.com www.sciencedirect.com
    Live Imaging of SARS-CoV-2 Infection in Mice Reveals that Neutralizing Antibodies Require Fc Function for Optimal Efficacy
    1
    1. scibot 23 Sep 2021
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.immuni.2021.08.015

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    sciencedirect.com/science/article/pii/S1074761321003472
  63. Aug 2021
  64. www.sciencedirect.com www.sciencedirect.com
    Convergent antibody responses to the SARS-CoV-2 spike protein in convalescent and vaccinated individuals
    1
    1. scibot 21 Aug 2021
      RRID:IMSR_JAX:03486

      DOI: 10.1016/j.celrep.2021.109604

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @Naa003

      SciCrunch record: RRID:IMSR_JAX:034860

      Curator comments: B6.Cg-Tg(K18-ACE2)2Prlmn/J Mus musculus IMSR Cat# JAX:034860

      What is this?
      RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:IMSR_JAX:034860
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    sciencedirect.com/science/article/pii/S2211124721010421
  65. Jul 2021
  66. 52.53.155.43 52.53.155.43
    An intranasal vaccine durably protects against SARS-CoV-2 variants in mice
    1
    1. scibot 23 Jul 2021
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.celrep.2021.109452

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    52.53.155.43/505882aeea4f51f2790a07d89e9823edcfae5813/pdf-html.html
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects
    1
    1. scibot 17 Jul 2021
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.celrep.2021.109353

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC8216847/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ultrapotent miniproteins targeting the SARS-CoV-2 receptor-binding domain protect against infection and disease
    1
    1. scibot 01 Jul 2021
      JAX:034860

      DOI: 10.1016/j.chom.2021.06.008

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC8221914/
  69. May 2021
  70. www.sciencedirect.com www.sciencedirect.com
    Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice
    1
    1. scibot 14 May 2021
      JAX:034860

      DOI: 10.1016/j.isci.2021.102479

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    sciencedirect.com/science/article/pii/S2589004221004478
  71. Apr 2021
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The antigenic anatomy of SARS-CoV-2 receptor binding domain
    1
    1. scibot 29 Apr 2021
      JAX:034860

      DOI: 10.1016/j.cell.2021.02.032

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC7891125/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation
    1
    1. scibot 14 Apr 2021
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.cell.2021.03.051

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:034860

      What is this?
      RRIDCUR:Validated RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC8008343/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibition Blocks Inflammation-Induced Cardiac Dysfunction and SARS-CoV-2 Infection
    1
    1. scibot 06 Apr 2021
      RRID:IMSR_JAX:034860

      DOI: 10.1016/j.cell.2021.03.026

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC7962543/
  75. Mar 2021
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
    1
    1. scibot 28 Mar 2021
      RRID:IMSR_JAX:03486

      DOI: 10.1016/j.cell.2021.03.029

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:034860

      What is this?
      RRIDCUR:Incorrect RRIDCUR:Unresolved RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC7962591/
  77. Feb 2021
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regen med therapeutic opportunities for fighting COVID‐19
    1
    1. scibot 27 Feb 2021
      JAX:034860

      DOI: 10.1002/sctm.20-0245

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @scibot

      SciCrunch record: RRID:IMSR_JAX:034860

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      RRID:IMSR_JAX:034860
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    ncbi.nlm.nih.gov/pmc/articles/PMC7461298/
  79. www.sciencedirect.com www.sciencedirect.com
    Replication-Competent Vesicular Stomatitis Virus Vaccine Vector Protects against SARS-CoV-2-Mediated Pathogenesis in Mice
    1
    1. scibot 24 Feb 2021
      JAX:034860

      DOI: 10.1016/j.chom.2020.07.018

      Resource: (IMSR Cat# JAX_034860,RRID:IMSR_JAX:034860)

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:034860

      What is this?
      RRIDCUR:Unresolved RRIDCUR:SyntaxError RRID:IMSR_JAX:034860
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    sciencedirect.com/science/article/pii/S1931312820304212
  80. Sep 2020
  81. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A Single-Dose Intranasal ChAd Vaccine Protects Upper and Lower Respiratory Tracts against SARS-CoV-2
    1
    1. scibot 16 Sep 2020
      RRID:IMSR_JAX:03486

      DOI: 10.1016/j.cell.2020.08.026

      Resource: IMSR_JAX:034860

      Curator: @evieth

      SciCrunch record: RRID:IMSR_JAX:034860

      What is this?
      RRID:IMSR_JAX:034860 RRIDCUR:Unresolved RRIDCUR:Incorrect
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    pubmed.ncbi.nlm.nih.gov/32931734/