105 Matching Annotations
  1. Last 7 days
  2. www.spiedigitallibrary.org www.spiedigitallibrary.org
    LPS-induced systemic inflammation reduced sensory stimulation-evoked astrocyte Ca2+ without altering the vascular response in the APP/PS1dE9 mouse model
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    spiedigitallibrary.org/conference-proceedings-of-spie/13303/1330303/LPS-induced-systemic-inflammation-reduced-sensory-stimulation-evoked-astrocyte-Ca2/10.1117/12.3043431.full
  3. www.biorxiv.org www.biorxiv.org
    Repetitive mild traumatic brain injury causes neuronal damage in the APP/PS1 mouse model of Alzheimer’s disease without an enduring impact on amyloid pathology, sleep, or epileptiform activity
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    biorxiv.org/content/10.1101/2025.06.06.658157v1
  4. Oct 2025
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Copper overload worsens the inflammatory response of microglia to amyloid beta (Aβ) by impairing phagocytosis and promoting mitochondrial DNA-mediated NLRP3 inflammasome activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12495055/
  6. Sep 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zolpidem restores sleep and slows Alzheimer’s progression in a mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12425003/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11160633/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differences in Learning Strategy Selection and Object Location Memory Impairments in APP/PS1 Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12426418/
  10. www.biorxiv.org www.biorxiv.org
    Systemic inflammation reduces astrocyte Ca2+ and neurovascular coupling in a mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2025.08.31.673380v1
  11. Aug 2025
  12. www.sciencedirect.com www.sciencedirect.com
    Positive Allosteric Modulation of M1 mAChRs with VU0486846 Reverses Cognitive Deficits in Male APPswe/PSEN1ΔE9 Alzheimer’s Mice
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    sciencedirect.com/science/article/pii/S0028390825003624
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    Andrographolide modulates glucose metabolism in visceral adipose tissue in an Alzheimer's disease obese mouse model
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    sciencedirect.com/science/article/pii/S0021925825024585
  14. www.sciencedirect.com www.sciencedirect.com
    Reconstructed cell-type-specific rhythms in human brain link Alzheimer’s pathology, circadian stress, and ribosomal disruption
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    sciencedirect.com/science/article/pii/S0896627325005173
  15. www.science.org www.science.org
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    science.org/doi/10.1126/sciadv.adw1732
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A wearable spatiotemporal controllable ultrasonic device with amyloid-β disaggregation for continuous Alzheimer’s disease therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309685/
  17. Jul 2025
  18. www.researchsquare.com www.researchsquare.com
    Cannabidiol modulates brain copper homeostasis in wild-type-like but not Alzheimer’s disease transgenic female mice: Implications for neuroprotective therapy
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    researchsquare.com/article/rs-6727849/v1
  19. link.springer.com link.springer.com
    Impaired hippocampal circuit function underlying memory encoding and consolidation precede robust Aβ deposition in a mouse model of alzheimer’s disease
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    link.springer.com/article/10.1038/s41598-025-05653-2
  20. Jun 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer’s Disease Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12154612/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lecanemab Binds to Transgenic Mouse Model‐Derived Amyloid‐β Fibril Structures Resembling Alzheimer's Disease Type I, Type II and Arctic Folds
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    pmc.ncbi.nlm.nih.gov/articles/PMC12152531/
  23. Mar 2025
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    CPNE7 Regulates Amyloidogenesis Through CAP1-Dependent ADAM10 Translation
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70026
  25. Feb 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Muscle Cathepsin B treatment improves behavioral and neurogenic deficits in a mouse model of Alzheimer’s Disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11785056/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Regulation of cell distancing in peri-plaque glial nets by Plexin-B1 affects glial activation and amyloid compaction in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11346591/
  28. Jan 2025
  29. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-024-00788-8.pdf
  30. link.springer.com link.springer.com
    SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
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    link.springer.com/article/10.1186/s13024-024-00788-8
  31. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225000112-main-html.html
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    52.53.155.43/f3927b613620da7ae9927001d3d9d5a924748cb9/1-s2.0-S2589004225000112-main-html.html
  32. Nov 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC2828687/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PET neuroimaging studies of [18F]CABS13 in a double transgenic mouse model of Alzheimer’s disease and non-human primates
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    pmc.ncbi.nlm.nih.gov/articles/PMC4879824/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Wnt-induced activation of glucose metabolism mediates the in vivo neuroprotective roles of Wnt signaling in Alzheimer disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC7680578/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11005245/
  37. Sep 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early hippocampal hyperexcitability and synaptic reorganization in mouse models of amyloidosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11388185/
  39. Aug 2024
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology, cognition, and behavior in APP/PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11317949/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chimeric antigen receptor macrophages target and resorb amyloid plaques
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    pmc.ncbi.nlm.nih.gov/articles/PMC11063938/
  42. www.frontiersin.org www.frontiersin.org
    LRRC25 expression during physiological aging and in mouse models of Alzheimer’s disease and iPSC-derived neurons
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    frontiersin.org/articles/10.3389/fnmol.2024.1365752
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-dependent effects of acute stress on amyloid-β in male and female mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10232275/
  44. www.frontiersin.org www.frontiersin.org
    Acute stressors do not impair short-term memory or attention in an aged mouse model of amyloidosis
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    frontiersin.org/articles/10.3389/fnbeh.2023.1151833
  45. www.frontiersin.org www.frontiersin.org
    Region-specific heterogeneity in neuronal nuclear morphology in young, aged and in Alzheimer’s disease mouse brains
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    frontiersin.org/articles/10.3389/fcell.2023.1032504
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7941983/
  47. Jul 2024
  48. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-024-00740-w
  49. May 2024
  50. www.frontiersin.org www.frontiersin.org
    Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer’s disease mice
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    frontiersin.org/articles/10.3389/fnmol.2024.1369781
  51. Apr 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034594/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    zpae022-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC11025629/
  54. www.sciencedirect.com www.sciencedirect.com
    Exercise-enhanced IGF1R sumoylation-induced nuclear translocation decreases neuroinflammation in alzheimer's mice
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    sciencedirect.com/science/article/pii/S2090123224001279
  55. www.sciencedirect.com www.sciencedirect.com
    The association of GNB5 with Alzheimer disease revealed by genomic analysis restricted to variants impacting gene function
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    sciencedirect.com/science/article/pii/S0002929724000053
  56. Jan 2024
  57. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-024-01076-8
  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13895
  59. www.mdpi.com www.mdpi.com
    Evaluation of Novel B1R/B2R Agonists Containing TRIOZAN™ Nanoparticles for Targeted Brain Delivery of Antibodies in a Mouse Model of Alzheimer Disease
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    mdpi.com/1420-3049/28/13/5206
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sleep-Deep-Net learns sleep wake scoring from the end-user and completes each record in their style
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    pmc.ncbi.nlm.nih.gov/articles/PMC10769368/
  61. cmjournal.biomedcentral.com cmjournal.biomedcentral.com
    Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway
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    cmjournal.biomedcentral.com/articles/10.1186/s13020-023-00722-y
  62. link.springer.com link.springer.com
    Natural and Pathological Aging Distinctively Impacts the Pheromone Detection System and Social Behavior
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    link.springer.com/article/10.1007/s12035-023-03362-3
  63. www.biorxiv.org www.biorxiv.org
    Neuroinflammation increases oxygen extraction in a mouse model of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.10.16.562353v1
  64. www.mdpi.com www.mdpi.com
    CRMP2 Participates in Regulating Mitochondrial Morphology and Motility in Alzheimer’s Disease
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    mdpi.com/2073-4409/12/9/1287
  65. www.mdpi.com www.mdpi.com
    Multi-Targeting Intranasal Nanoformulation as a Therapeutic for Alzheimer’s Disease
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    mdpi.com/2218-273X/13/2/232
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deletion of Small GTPase H-Ras Rescues Memory Deficits and Reduces Amyloid Plaque-Associated Dendritic Spine Loss in Transgenic Alzheimer’s Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10771223/
  67. www.nature.com www.nature.com
    Cryo-EM of Aβ fibrils from mouse models find tg-APPArcSwe fibrils resemble those found in patients with sporadic Alzheimer’s disease
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    nature.com/articles/s41593-023-01484-4
  68. www.biorxiv.org www.biorxiv.org
    Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2023.07.24.547147v1
  69. journals.plos.org journals.plos.org
    Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein
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    journals.plos.org/plosone/article
  70. Sep 2023
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ligustilide-loaded liposome ameliorates mitochondrial impairments and improves cognitive function via the PKA/AKAP1 signaling pathway in a mouse model of Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10916432/
  72. Aug 2023
  73. www.sciencedirect.com www.sciencedirect.com
    MALDI mass spectrometry imaging discloses the decline of sulfoglycosphingolipid and glycerophosphoinositol species in the brain regions related to cognition in a mouse model of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0039914023007737
  74. May 2023
  75. www.mdpi.com www.mdpi.com
    DEAD-Box Helicase 17 Promotes Amyloidogenesis by Regulating BACE1 Translation
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    mdpi.com/2076-3425/13/5/745
  76. www.mdpi.com www.mdpi.com
    The Memory Benefit to Aged APP/PS1 Mice from Long-Term Intranasal Treatment of Low-Dose THC
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    mdpi.com/1422-0067/23/8/4253/htm
  77. Apr 2023
  78. www.biorxiv.org www.biorxiv.org
    Cryo-EM Structures of Amyloid-β Fibrils from Alzheimer’s Disease Mouse Models
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    biorxiv.org/content/10.1101/2023.03.30.534981v1
  79. Mar 2023
  80. www.biorxiv.org www.biorxiv.org
    Natural and pathological aging distinctively impact the vomeronasal detection system and social behavior
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    biorxiv.org/content/10.1101/2022.08.31.505522v4
  81. www.frontiersin.org www.frontiersin.org
    Trans ε-Viniferin Decreases Amyloid Deposits With Greater Efficiency Than Resveratrol in an Alzheimer’s Mouse Model
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    frontiersin.org/articles/10.3389/fnins.2021.803927/full
  82. www.science.org www.science.org
    Molecular basis of astrocyte diversity and morphology across the CNS in health and disease
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    science.org/doi/10.1126/science.adc9020
  83. www.mdpi.com www.mdpi.com
    Ginsenoside F1 Protects the Brain against Amyloid Beta-Induced Toxicity by Regulating IDE and NEP
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    mdpi.com/2075-1729/12/1/58
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic effects of blast injury on the microvasculature in a transgenic mouse model of Alzheimer’s disease related Aβ amyloidosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC8751260/
  85. www.biorxiv.org www.biorxiv.org
    Impact of cellular prion protein expression on disease progression and pathology in two mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2022.09.25.508690v1
  86. journals.lww.com journals.lww.com
    Inhibiting 5-hydroxytryptamine receptor 3 alleviates... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/09000/Inhibiting_5_hydroxytryptamine_receptor_3.30.aspx
  87. Feb 2023
  88. Local file Local file
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  89. Jan 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial Expression of the Wnt Signaling Modulator DKK2 Differs between Human Alzheimer’s Disease Brains and Mouse Neurodegeneration Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC9836029/
  91. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2022/06000/guardians_of_the_eye__new_tales_about_retinal.24.aspx
  92. Dec 2022
  93. journals.lww.com journals.lww.com
    Hub genes and key pathways of traumatic brain injury:... : Neural Regeneration Research
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    journals.lww.com/nrronline/fulltext/2022/06000/guardians_of_the_eye__new_tales_about_retinal.24.aspx
  94. Oct 2022
  95. www.nature.com www.nature.com
    A distinct astrocyte subtype in the aging mouse brain characterized by impaired protein homeostasis
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    nature.com/articles/s43587-022-00257-1
  96. Jul 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex-Related Microglial Perturbation Is Related to Mitochondrial Changes in a Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC9297004/
  98. Jun 2022
  99. www.sciencedirect.com www.sciencedirect.com
    Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S1550413122001930
  100. Apr 2022
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Age and Alzheimer’s Disease-Related Oligodendrocyte Changes in Hippocampal Subregions
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    ncbi.nlm.nih.gov/pmc/articles/PMC9023310/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Longitudinal Assessment of Working Memory Performance in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease Using an Automated Figure-8-Maze
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    ncbi.nlm.nih.gov/pmc/articles/PMC8155296/
  103. www.nature.com www.nature.com
    Inhibition of the CEBPβ-NFκB interaction by nanocarrier-packaged Carnosic acid ameliorates glia-mediated neuroinflammation and improves cognitive function in an Alzheimer’s disease model
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    nature.com/articles/s41419-022-04765-1
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
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    ncbi.nlm.nih.gov/pmc/articles/PMC8247905/
  105. Feb 2022
  106. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A M1 muscarinic acetylcholine receptor positive allosteric modulator improves pathology and cognitive deficits in female APPswe/PSEN1ΔE9 mice
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15750
  107. Nov 2021
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Microbiota Sensing – Free Fatty Acid Receptor 2 Signaling Ameliorates Amyloid-β Induced Neurotoxicity by Modulating Proteolysis-Senescence Axis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8544178/
  109. Jul 2021
  110. molecularbrain.biomedcentral.com molecularbrain.biomedcentral.com
    Minor ginsenoside F1 improves memory in APP/PS1 mice
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    molecularbrain.biomedcentral.com/articles/10.1186/s13041-019-0495-7
  111. www.spiedigitallibrary.org www.spiedigitallibrary.org
    Revealing brain pathologies with multimodal visible light optical coherence microscopy and fluorescence imaging
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    spiedigitallibrary.org/journals/journal-of-biomedical-optics/volume-24/issue-06/066010/Revealing-brain-pathologies-with-multimodal-visible-light-optical-coherence-microscopy/10.1117/1.JBO.24.6.066010.full
  112. Jun 2021
  113. www.sciencedirect.com www.sciencedirect.com
    Hippocampal sub-networks exhibit distinct spatial representation deficits in Alzheimer’s disease model mice
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  114. www.nature.com www.nature.com
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  115. May 2021
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    Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease
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  117. Mar 2021
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  119. Jan 2021
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  123. Dec 2020
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  125. Sep 2020
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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  130. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  131. Jan 2020
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  133. www.frontiersin.org www.frontiersin.org
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  135. Nov 2018
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  137. www.tandfonline.com www.tandfonline.com
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  139. www.sciencedirect.com www.sciencedirect.com
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  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
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