160 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of transcriptomic changes in the neurovascular unit of Alzheimiers transgenic mouse models using digital spatial profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148062/
  3. Oct 2025
  4. www.sciencedirect.com www.sciencedirect.com
    AMPKα2 signals amino acid insufficiency to inhibit protein synthesis
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    sciencedirect.com/science/article/pii/S1550413125003894
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Serum amyloid P secreted by bone marrow adipocytes drives skeletal amyloidosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12443615/
  6. Sep 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-specific transcriptomic profiling reveals key players in bone loss associated with Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12397463/
  8. www.biorxiv.org www.biorxiv.org
    Sex-dependent interferon signaling drives female-biased vulnerability in Alzheimer’s disease
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    biorxiv.org/content/10.1101/2025.08.22.671724v3
  9. Jul 2025
  10. www.sciencedirect.com www.sciencedirect.com
    Aromatase inhibition modulates intrinsic properties and excitability of hippocampal CA1 pyramidal cells in the APP/PS1 mouse model of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S0014488625002298
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    1-s2.0-S2589004225013811-main-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC12329260/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intermittent supplementation with Akkermansia muciniphila and galactooligosaccharides modulates Alzheimer’s disease progression, gut microbiota, and colon short-chain fatty acid profiles in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12256538/
  13. Jun 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for culture, purification, and target validation of a hybridoma-generated monoclonal antibody targeting Aβ truncated species
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    pmc.ncbi.nlm.nih.gov/articles/PMC12167800/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring Iron Deposition Patterns Using Light and Electron Microscopy in the Mouse Brain Across Aging and Alzheimer's Disease Pathology Conditions
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    pmc.ncbi.nlm.nih.gov/articles/PMC12138743/
  16. May 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification and validation of pyroptosis-related genes in Alzheimer’s disease based on multi-transcriptome and machine learning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12116433/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repetitive transcranial magnetic stimulation increases synaptic plasticity of cortical axons in the APP/PS1 amyloidosis mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12119023/
  19. www.sciencedirect.com www.sciencedirect.com
    Selectively vulnerable deep cortical layer 5/6 fast-spiking interneurons in Alzheimer’s disease models in vivo
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    sciencedirect.com/science/article/pii/S0896627325002934
  20. www.cell.com www.cell.com
    Alzheimer’s disease patient-derived high-molecular-weight tau impairs bursting in hippocampal neurons
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    cell.com/cell/fulltext/S0092-8674(25)00408-8
  21. Apr 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Omega-3 EPA Supplementation Shapes the Gut Microbiota Composition and Reduces Major Histocompatibility Complex Class II in Aged Wild-Type and APP/PS1 Alzheimer’s Mice: A Pilot Experimental Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11990804/
  23. Mar 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    On-Tissue Chemical Derivatization for Mass Spectrometry Imaging of Fatty Acids with Enhanced Detection Sensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11940502/
  25. Feb 2025
  26. 52.53.155.43 52.53.155.43
    Epigenetic derepression of H3K9me3 mitigates Alzheimer-related pathology and improves cognition via immunomodulation and Vgf induction
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    52.53.155.43/e4e90ae1183345368613165c2c51b59fe206bc18/2024.10.15.618518.full-html.html
  27. Jan 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thermotherapy has sexually dimorphic responses in APP/PS1 mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11719106/
  29. www.jbc.org www.jbc.org
    A conformation-specific antibody against oligomeric β-amyloid restores neuronal integrity in a mouse model of Alzheimer's disease
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    jbc.org/article/S0021-9258(21)00005-3/fulltext
  30. link.springer.com link.springer.com
    Pseudogene Lamr1-ps1 Aggravates Early Spatial Learning Memory Deficits in Alzheimer’s Disease Model Mice
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    link.springer.com/article/10.1007/s12264-024-01336-6
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FUBP3 mediates the amyloid-β-induced neuronal NLRP3 expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11691456/
  32. Dec 2024
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Amyloid-β oligomers trigger sex-dependent inhibition of GIRK channel activity in hippocampal neurons in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11600338/
  34. journals.sagepub.com journals.sagepub.com
    DJ-1-mediated repression of the RNA-binding protein FMRP is predicted to impact known Alzheimer's disease-related protein networks
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    journals.sagepub.com/doi/full/10.1177/13872877241291175
  35. Nov 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma membrane repair defect in Alzheimer's disease neurons is driven by the reduced dysferlin expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC11486262/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Il10 deficiency re-balances innate immunity to mitigate Alzheimer-like pathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC4352138/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC3980584/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Meox2 haploinsufficiency increases neuronal cell loss in a mouse model of Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC4878023/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC6457346/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neutrophils as a potential therapeutic target in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10020508/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC10996586/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hyperfunction of post-synaptic density protein 95 promotes seizure response in early-stage aβ pathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC10933348/
  44. Oct 2024
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockdown of microglial iron import gene, Slc11a2, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11438269/
  46. Sep 2024
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    <em>Brain Pathology</em> | ISN Neuropathology Journal | Wiley Online Library
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    onlinelibrary.wiley.com/doi/10.1111/bpa.13279
  48. Aug 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective disruption of synaptic NMDA receptors of the hippocampal trisynaptic circuit in Aβ pathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC11340147/
  50. www.frontiersin.org www.frontiersin.org
    The role of ADAM17 in cerebrovascular and cognitive function in the APP/PS1 mouse model of Alzheimer’s disease
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    frontiersin.org/articles/10.3389/fnmol.2023.1125932
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/epi.17355
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Altered synaptic glutamate homeostasis contributes to cognitive decline in young APP/PSEN1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC8457528/
  53. www.tandfonline.com www.tandfonline.com
    Early loss of cerebellar Purkinje cells in human and a transgenic mouse model of Alzheimer’s disease
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    tandfonline.com/doi/full/10.1080/01616412.2021.1893566
  54. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia
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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-022-00547-7
  55. Jul 2024
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Beneficial effects of physical exercise and an orally active mGluR2/3 antagonist pro-drug on neurogenesis and behavior in an Alzheimer's amyloidosis model
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    pmc.ncbi.nlm.nih.gov/articles/PMC11285632/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MGST3 regulates BACE1 protein translation and amyloidogenesis by controlling the RGS4-mediated AKT signaling pathway
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    pmc.ncbi.nlm.nih.gov/articles/PMC11332907/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Knockdown of microglial iron import gene, DMT1, worsens cognitive function and alters microglial transcriptional landscape in a sex-specific manner in the APP/PS1 model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11230470/
  59. www.sciencedirect.com www.sciencedirect.com
    Ascorbate insufficiency disrupts glutamatergic signaling and alters electroencephalogram phenotypes in a mouse model of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S096999612400202X
  60. Jun 2024
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vascular dysfunction occurs prior to the onset of amyloid pathology and Aβ plaque deposits colocalize with endothelial cells in the hippocampus of female APPswe/PSEN1dE9 mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11493946/
  62. www.sciencedirect.com www.sciencedirect.com
    STAU1 exhibits a dual function by promoting amyloidogenesis and tau phosphorylation in cultured cells
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    sciencedirect.com/science/article/pii/S0014488624001316
  63. May 2024
  64. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Beta-amyloid interacts with and activates the long-form phosphodiesterase PDE4D5 in neuronal cells to reduce cAMP availability
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1873-3468.14902
  65. www.life-science-alliance.org www.life-science-alliance.org
    Distinct calcium sources regulate temporal profiles of NMDAR and mGluR-mediated protein synthesis
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    life-science-alliance.org/content/lsa/7/8/e202402594.full.pdf
  66. Apr 2024
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for evaluating mutualistic cooperative behavior in mice using a water-reward task assay
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    pmc.ncbi.nlm.nih.gov/articles/PMC11047788/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VEGF signalling causes stalls in brain capillaries and reduces cerebral blood flow in Alzheimer’s mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9150081/
  69. watermark.silverchair.com watermark.silverchair.com
    awae015.pdf
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    watermark.silverchair.com/awae015.pdf
  70. journals.plos.org journals.plos.org
    Sex- and region-specific cortical and hippocampal whole genome transcriptome profiles from control and APP/PS1 Alzheimer’s disease mice
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    journals.plos.org/plosone/article
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11032532/
  72. Mar 2024
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sustained meningeal lymphatic vessel atrophy or expansion does not alter Alzheimer’s disease-related amyloid pathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC7616318/
  74. Feb 2024
  75. content.iospress.com content.iospress.com
    Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad230089
  76. content.iospress.com content.iospress.com
    Telmisartan Alleviates Alzheimer’s Disease-Related Neuropathologies and Cognitive Impairments
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad230133
  77. Jan 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC10797952/
  79. www.sciencedirect.com www.sciencedirect.com
    Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology
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    sciencedirect.com/science/article/pii/S0969996124000032
  80. link.springer.com link.springer.com
    Integrative Analysis of the Age-Related Dysregulated Genes Reveals an Inflammation and Immunity-Associated Regulatory Network in Alzheimer’s Disease
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    link.springer.com/article/10.1007/s12035-023-03900-z
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Akt activation ameliorates deficits in hippocampal-dependent memory and activity-dependent synaptic protein synthesis in an Alzheimer’s disease mouse model
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    pmc.ncbi.nlm.nih.gov/articles/PMC10839450/
  82. www.sciencedirect.com www.sciencedirect.com
    Multi-transcriptomics reveals brain cellular responses to peripheral infection in Alzheimer’s disease model mice
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    sciencedirect.com/science/article/pii/S2211124723007969
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune-mediated platelet depletion augments Alzheimer’s disease neuropathological hallmarks in APP-PS1 mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9970308/
  84. www.mdpi.com www.mdpi.com
    Downregulation of Sirtuin 1 Does Not Account for the Impaired Long-Term Potentiation in the Prefrontal Cortex of Female APPswe/PS1dE9 Mice Modelling Alzheimer’s Disease
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    mdpi.com/1422-0067/24/8/6968
  85. www.mdpi.com www.mdpi.com
    Plasma Exchange Reduces Aβ Levels in Plasma and Decreases Amyloid Plaques in the Brain in a Mouse Model of Alzheimer’s Disease
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    mdpi.com/1422-0067/24/23/17087
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuronally Derived Soluble Abeta Evokes Cell-Wide Astrocytic Calcium Dysregulation in Absence of Amyloid Plaques in Vivo
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    pmc.ncbi.nlm.nih.gov/articles/PMC10312057/
  87. www.sciencedirect.com www.sciencedirect.com
    Whole genome transcriptome data from the WT cortex and hippocampus of female and male control and APP/PS1 Alzheimer's disease mice
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    sciencedirect.com/science/article/pii/S2352340923006856
  88. link.springer.com link.springer.com
    Dietary Fiber Modulates the Release of Gut Bacterial Products Preventing Cognitive Decline in an Alzheimer’s Mouse Model
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    link.springer.com/article/10.1007/s10571-022-01268-7
  89. Oct 2023
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modification of astrocytic Cx43 hemichannel activity in animal models of AD: modulation by adenosine A2A receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC10613596/
  91. Sep 2023
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Endothelial senescence alleviates cognitive impairment in a mouse model of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/10.1002/glia.24461
  93. Aug 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasmon-activated water as a therapeutic strategy in Alzheimer’s disease by altering gut microbiota
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    ncbi.nlm.nih.gov/pmc/articles/PMC10449311/
  95. Jul 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ketogenic diet alleviates cognitive dysfunction and neuroinflammation in APP/PS1 mice via the Nrf2/HO-1 and NF-κB signaling pathways
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    ncbi.nlm.nih.gov/pmc/articles/PMC10358659/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prodromal Glutamatergic Modulation with Riluzole Impacts Glucose Homeostasis and Spatial Cognition in Alzheimer’s Disease Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10357216/
  98. Jun 2023
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early chronic suppression of microglial p38α in a model of Alzheimer’s disease does not significantly alter amyloid-associated neuropathology
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    ncbi.nlm.nih.gov/pmc/articles/PMC10231773/
  100. May 2023
  101. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Parallels between retinal and brain pathology and response to immunotherapy in old, late‐stage Alzheimer's disease mouse models
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13246
  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Longitudinal intravital imaging of cerebral microinfarction reveals a dynamic astrocyte reaction leading to glial scar formation
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.24151
  103. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease
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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13380
  104. Apr 2023
  105. www.nature.com www.nature.com
    Sex difference in evolution of cognitive decline: studies on mouse model and the Dominantly Inherited Alzheimer Network cohort
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    nature.com/articles/s41398-023-02411-8
  106. Mar 2023
  107. link.springer.com link.springer.com
    Physiological β-amyloid clearance by the liver and its therapeutic potential for Alzheimer’s disease
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    link.springer.com/article/10.1007/s00401-023-02559-z
  108. www.nature.com www.nature.com
    Reactive astrocytes acquire neuroprotective as well as deleterious signatures in response to Tau and Aß pathology
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    nature.com/articles/s41467-021-27702-w
  109. www.sciencedirect.com www.sciencedirect.com
    Gene therapy using Aβ variants for amyloid reduction
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    sciencedirect.com/science/article/pii/S1525001621001295
  110. www.biorxiv.org www.biorxiv.org
    Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burden
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    biorxiv.org/content/10.1101/2022.11.14.516510v2
  111. www.biorxiv.org www.biorxiv.org
    Intravital imaging of cerebral microinfarct reveals an astrocyte reaction led to glial scar
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    biorxiv.org/content/10.1101/2021.09.29.462492v1
  112. www.sciencedirect.com www.sciencedirect.com
    Both male and female APPswe/PSEN1dE9 mice are impaired in spatial memory and cognitive flexibility at 9 months of age
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  113. journals.plos.org journals.plos.org
    Selection of single domain anti-transferrin receptor antibodies for blood-brain barrier transcytosis using a neurotensin based assay and histological assessment of target engagement in a mouse model of Alzheimer’s related amyloid-beta pathology
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    Reduced mitochondria membrane potential and lysosomal acidification are associated with decreased oligomeric Aβ degradation induced by hyperglycemia: A study of mixed glia cultures
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  115. www.biorxiv.org www.biorxiv.org
    Silencing of ApoE with Divalent siRNAs Drives Activation of Immune Clearance Pathways and Improves Amyloid Pathology in Mouse Models of Alzheimer’s Disease
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  116. journals.plos.org journals.plos.org
    Therapeutic treatment with the anti-inflammatory drug candidate MW151 may partially reduce memory impairment and normalizes hippocampal metabolic markers in a mouse model of comorbid amyloid and vascular pathology
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  117. www.biorxiv.org www.biorxiv.org
    Real-time imaging of mitochondrial redox reveals increased mitochondrial oxidative stress associated with amyloid β aggregates in vivo in a mouse model of Alzheimer’s disease
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  118. actaneurocomms.biomedcentral.com actaneurocomms.biomedcentral.com
    Neutrophil-vascular interactions drive myeloperoxidase accumulation in the brain in Alzheimer’s disease
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  119. Feb 2023
  120. www.sciencedirect.com www.sciencedirect.com
    The impact of a high-sodium diet regimen on cerebrovascular morphology and cerebral perfusion in Alzheimer's disease
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  121. jnanobiotechnology.biomedcentral.com jnanobiotechnology.biomedcentral.com
    Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain
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  122. Jan 2023
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    Motor Cortex Theta and Gamma Architecture in Young Adult APPswePS1dE9 Alzheimer Mice
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  124. www.ahajournals.org www.ahajournals.org
    Loss of Endothelial Nitric Oxide Synthase Promotes p25 Generation and Tau Phosphorylation in a Murine Model of Alzheimer’s Disease | Circulation Research
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    ahajournals.org/doi/full/10.1161/CIRCRESAHA.116.309686
  125. Dec 2022
  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Chronic, Mild Hypothermic Environmental Temperature does not Ameliorate Cognitive Deficits in an Alzheimer’s Disease Mouse
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  127. Nov 2022
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Visual-stimuli Four-arm Maze test to Assess Cognition and Vision in Mice
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  129. Oct 2022
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A surrogate marker for very early-stage tau pathology is detectable by molecular magnetic resonance imaging
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  131. Aug 2022
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation
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  133. Jun 2022
  134. journals.lww.com journals.lww.com
    Lamotrigine protects against cognitive deficits, synapse... : Neural Regeneration Research
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  135. May 2022
  136. www.sciencedirect.com www.sciencedirect.com
    Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo
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  137. Apr 2022
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-Term Consequence of Non-neurotropic H3N2 Influenza A Virus Infection for the Progression of Alzheimer’s Disease Symptoms
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Age-Dependent Shift of AMPA Receptors From Synapses to Intracellular Compartments in Alzheimer’s Disease: Immunocytochemical Analysis of the CA1 Hippocampal Region in APP/PS1 Transgenic Mouse Model
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DBA/2J Genetic Background Exacerbates Spontaneous Lethal Seizures but Lessens Amyloid Deposition in a Mouse Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC4416920/
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer's Disease
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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endoplasmic reticulum acetyltransferases Atase1 and Atase2 differentially regulate reticulophagy, macroautophagy and cellular acetyl-CoA metabolism
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    Mitochondrial ubiquitin ligase alleviates Alzheimer’s disease pathology via blocking the toxic amyloid-β oligomer generation
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reactive astrocytes as treatment targets in Alzheimer's disease—Systematic review of studies using the APPswePS1dE9 mouse model
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  150. Mar 2022
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    ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
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  152. Oct 2021
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    The Expression and Localisation of G-Protein-Coupled Inwardly Rectifying Potassium (GIRK) Channels Is Differentially Altered in the Hippocampus of Two Mouse Models of Alzheimer’s Disease
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparison of the Amyloid Load in the Brains of Two Transgenic Alzheimer’s Disease Mouse Models Quantified by Florbetaben Positron Emission Tomography
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  155. Sep 2021
  156. www.sciencedirect.com www.sciencedirect.com
    Spreading of Alzheimer Tau seeds is enhanced by aging and template matching with limited impact of amyloid-β
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  157. Aug 2021
  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology
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  159. www.jneurosci.org www.jneurosci.org
    Social Interaction Rescues Memory Deficit in an Animal Model of Alzheimer's Disease by Increasing BDNF-Dependent Hippocampal Neurogenesis
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  160. www.nature.com www.nature.com
    Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models
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  161. www.jneurosci.org www.jneurosci.org
    Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss
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  162. Jul 2021
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ageing and amyloidosis underlie the molecular and pathological alterations of tau in a mouse model of familial Alzheimer’s disease
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  164. academic.oup.com academic.oup.com
    Peripherally derived angiotensin converting enzyme-enhanced macrophages alleviate Alzheimer-related disease
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ApoA-I deficiency increases cortical amyloid deposition, cerebral amyloid angiopathy, cortical and hippocampal astrogliosis, and amyloid-associated astrocyte reactivity in APP/PS1 mice
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  166. www.sciencedirect.com www.sciencedirect.com
    Doxycycline counteracts neuroinflammation restoring memory in Alzheimer's disease mouse models
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment
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  168. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interrelationship between the 5-lipoxygenase pathway and microbial dysbiosis in the progression of Alzheimer's disease
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increasing cerebral blood flow improves cognition into late stages in Alzheimer’s disease mice
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  170. Apr 2021
  171. www.sciencedirect.com www.sciencedirect.com
    Quantifying molecular aggregation by super resolution microscopy within an excitatory synapse from mouse hippocampal neurons
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer’s disease
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  173. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TUFM is involved in Alzheimer’s disease‐like pathologies that are associated with ROS
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  174. Feb 2021
  175. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15184
  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease
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  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A validated quantitative method for the assessment of neuroprotective barrier impairment in neurodegenerative disease models
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15119
  178. Jan 2021
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Color and contrast vision in mouse models of aging and Alzheimer’s disease using a novel visual-stimuli four-arm maze
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  180. www.jbc.org www.jbc.org
    A conformation specific antibody against Oligomeric β-Amyloid Restores Neuronal Integrity in a Mouse Model of Alzheimer’s Disease
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  181. Nov 2020
  182. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Riluzole Attenuates Glutamatergic Tone and Cognitive Decline in AβPP/PS1 Mice.
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15224
  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergence in the metabolome between natural aging and Alzheimer’s disease
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pilot study investigating the effects of voluntary exercise on capillary stalling and cerebral blood flow in the APP/PS1 mouse model of Alzheimer’s disease
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  185. Sep 2020
  186. www.nature.com www.nature.com
    Increased mitochondrial calcium levels associated with neuronal death in a mouse model of Alzheimer’s disease
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hippocampal alterations in glutamatergic signaling during amyloid progression in AβPP/PS1 mice
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High fat diet worsens Alzheimer’s disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    LY379268 Does Not Have Long-Term Procognitive Effects nor Attenuate Glutamatergic Signaling in AβPP/PS1 Mice
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  190. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AβPP/PS1 Mice
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  191. www.frontiersin.org www.frontiersin.org
    Activated Bone Marrow-Derived Macrophages Eradicate Alzheimer's-Related Aβ42 Oligomers and Protect Synapses
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  192. link.springer.com link.springer.com
    Identification of early pericyte loss and vascular amyloidosis in Alzheimer’s disease retina
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  193. journals.ke-i.org journals.ke-i.org
    Non-invasive Brain Delivery and Efficacy of BDNF in APP/PS1 Transgenic Mice
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  194. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia
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  195. Jan 2020
  196. journals.sagepub.com journals.sagepub.com
    Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer’s Disease Progression
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  197. www.jneurosci.org www.jneurosci.org
    Alzheimer's Disease Risk Factor Pyk2 Mediates Amyloid-β-Induced Synaptic Dysfunction and Loss
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  198. May 2019
  199. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  200. www.sciencedirect.com www.sciencedirect.com
    Chronic sleep fragmentation exacerbates amyloid β deposition in Alzheimer’s disease model mice
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  201. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Optogenetic stimulation of dentate gyrus engrams restores memory in Alzheimer&apos;s disease mice
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    onlinelibrary.wiley.com/doi/10.1002/hipo.22756/full
  202. www.nature.com www.nature.com
    Chronic consumption of a western diet induces robust glial activation in aging mice and in a mouse model of Alzheimer’s disease
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  203. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Nuclear receptor agonist-driven modification of inflammation and amyloid pathology enhances and sustains cognitive improvements in a mouse model of Alzheimer’s disease
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  204. www.sciencedirect.com www.sciencedirect.com
    Co-housing reverses memory decline by epigenetic regulation of brain-derived neurotrophic factor expression in an animal model of Alzheimer’s disease
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    Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus
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  206. www.jneurosci.org www.jneurosci.org
    Social Interaction Rescues Memory Deficit in an Animal Model of Alzheimer's Disease by Increasing BDNF-Dependent Hippocampal Neurogenesis
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