48 Matching Annotations
  1. Jul 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficient in vivo pharmacological inhibition of ΔFOSB, an AP-1 transcription factor, in brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC13288968/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial oxidative stress promotes the accumulation of advanced glycation end products
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    pmc.ncbi.nlm.nih.gov/articles/PMC13289938/
  4. May 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PINK1-dependent NFKB signaling contributes to amyloid pathology in Alzheimer disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12758239/
  6. Apr 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Parvalbumin Neuron–Targeted Loss of Alzheimer’s Disease Risk Gene BIN1 Is Insufficient to Drive Cognitive or Network Excitability Changes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13064429/
  8. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Decline in Metabotropic Glutamate mGlu3 Receptor Levels Is Associated With Amyloid Plaques in Alzheimer's Disease and Is Detectable in Serum During Mild Cognitive Impairment
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70417
  9. Mar 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Noradrenergic innervation across brain regions is altered by aging and by disease progression in a mouse model of Alzheimer’s disease neuropathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC12915906/
  11. Feb 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Discovery of small molecules and a druggable groove that regulate DNA binding and release of the AP-1 transcription factor ΔFOSB
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    pmc.ncbi.nlm.nih.gov/articles/PMC12861233/
  13. Nov 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Meningeal vascular Aβ deposition associates with cerebral hypoperfusion and compensatory collateral remodeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616917/
  15. Oct 2025
  16. www.sciencedirect.com www.sciencedirect.com
    Tropisetron modulates the firing activity of pyramidal and fast-spiking hippocampal CA1 neurons in a mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S0304394025002496
  17. www.sciencedirect.com www.sciencedirect.com
    Traumatic brain injury induces a sustained sensorimotor impairment associated with a dysregulated acute phase response in mice overexpressing human amyloid precursor protein
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    sciencedirect.com/science/article/pii/S0889159125002971
  18. www.biorxiv.org www.biorxiv.org
    Meningeal vascular Aβ deposition associates with cerebral hypoperfusion and compensatory collateral remodeling
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    biorxiv.org/content/10.1101/2025.02.05.635937v3
  19. Jul 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hemodynamic and neuronal contributions to low-frequency vascular oscillations in a preclinical model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12285523/
  21. Feb 2025
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional connectivity favors aberrant visual network c-Fos expression accompanied by cortical synapse loss in a mouse model of Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC11810533/
  23. Dec 2024
  24. www.sciencedirect.com www.sciencedirect.com
    β-hydroxybutyrate is a metabolic regulator of proteostasis in the aged and Alzheimer disease brain
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    sciencedirect.com/science/article/pii/S2451945624004598
  25. Nov 2024
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immuno-digital invasive cleavage assay for analyzing Alzheimer’s amyloid ß-bound extracellular vesicles
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    pmc.ncbi.nlm.nih.gov/articles/PMC9528138/
  27. Aug 2024
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Q/R editing site of AMPA receptor GluA2 subunit acts as an epigenetic switch regulating dendritic spines, neurodegeneration and cognitive deficits in Alzheimer’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC10537207/
  29. content.iospress.com content.iospress.com
    Activation of TNF Receptor 2 Improves Synaptic Plasticity and Enhances Amyloid-β Clearance in an Alzheimer’s Disease Mouse Model with Humanized TNF Receptor 2
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221230
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC5063569/
  31. www.cell.com www.cell.com
    Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein
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    cell.com/stem-cell-reports/pdfExtended/S2213-6711(16)30186-2
  32. www.pnas.org www.pnas.org
    A TNF receptor 2 agonist ameliorates neuropathology and improves cognition in an Alzheimer’s disease mouse model
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    pnas.org/doi/full/10.1073/pnas.2201137119
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.25207
  34. Mar 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Promotion of structural plasticity in area V2 of visual cortex prevents against object recognition memory deficits in aging and Alzheimer's disease rodents
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    ncbi.nlm.nih.gov/pmc/articles/PMC10960297/
  36. Jan 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Aberrant serotonergic signaling contributes to the hyperexcitability of CA1 pyramidal neurons in a mouse model of Alzheimer’s disease
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    sciencedirect.com/science/article/pii/S2211124723001638
  38. www.sciencedirect.com www.sciencedirect.com
    Grid cell disruption in a mouse model of early Alzheimer’s disease reflects reduced integration of self-motion cues
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    sciencedirect.com/science/article/pii/S096098222300547X
  39. www.mdpi.com www.mdpi.com
    The Expression of Epac2 and GluA3 in an Alzheimer’s Disease Experimental Model and Postmortem Patient Samples
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    mdpi.com/2227-9059/11/8/2096
  40. journals.plos.org journals.plos.org
    Two mouse models of Alzheimer’s disease accumulate amyloid at different rates and have distinct Aβ oligomer profiles unaltered by ablation of cellular prion protein
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    journals.plos.org/plosone/article
  41. Jun 2023
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting Amyloid Beta Deposition Using Distinct Strains of the Neurotropic Parasite Toxoplasma gondii as a Novel Tool
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    ncbi.nlm.nih.gov/pmc/articles/PMC5565021/
  43. journals.sagepub.com journals.sagepub.com
    Dissecting Amyloid Beta Deposition Using Distinct Strains of the Neurotropic Parasite Toxoplasma gondii as a Novel ToolASN Neuro - Carla M. Cabral, Kathryn E. McGovern, Wes R. MacDonald, Jenna Franco, Anita A. Koshy, 2017
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    journals.sagepub.com/doi/full/10.1177/1759091417724915
  44. Mar 2023
  45. rupress.org rupress.org
    GSAP regulates lipid homeostasis and mitochondrial function associated with Alzheimer’s disease
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    rupress.org/jem/article/218/8/e20202446/212404/GSAP-regulates-lipid-homeostasis-and-mitochondrial
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Assessment of neurovascular coupling and cortical spreading depression in mixed mouse models of atherosclerosis and Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752088/
  47. www.biorxiv.org www.biorxiv.org
    Grid cell disruption in a mouse model of early Alzheimer’s disease reflects reduced integration of self-motion cues and increased influence of environmental geometry
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    biorxiv.org/content/10.1101/2022.12.15.520595v1
  48. www.nature.com www.nature.com
    Disruption of the grid cell network in a mouse model of early Alzheimer’s disease
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    nature.com/articles/s41467-022-28551-x
  49. www.biorxiv.org www.biorxiv.org
    Impact of cellular prion protein expression on disease progression and pathology in two mouse models of Alzheimer’s disease
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    biorxiv.org/content/10.1101/2022.09.25.508690v1
  50. Apr 2022
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Practical considerations for choosing a mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC5741956/
  52. Jan 2022
  53. www.sciencedirect.com www.sciencedirect.com
    Modulating adult neurogenesis affects synaptic plasticity and cognitive functions in mouse models of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S2213671121005841
  54. Sep 2021
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8390308/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dementia model mice exhibited improvements of neuropsychiatric symptoms as well as cognitive dysfunction with neural cell transplantation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8390309/
  57. Jul 2021
  58. www.nature.com www.nature.com
    Plant sphingolipids promote extracellular vesicle release and alleviate amyloid-β pathologies in a mouse model of Alzheimer’s disease
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    nature.com/articles/s41598-019-53394-w
  59. www.sciencedirect.com www.sciencedirect.com
    Early Seizure Activity Accelerates Depletion of Hippocampal Neural Stem Cells and Impairs Spatial Discrimination in an Alzheimer’s Disease Model
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    sciencedirect.com/science/article/pii/S2211124719307405
  60. stke.sciencemag.org stke.sciencemag.org
    Pharmacologic inhibition of LIMK1 provides dendritic spine resilience against β-amyloid
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    stke.sciencemag.org/content/12/587/eaaw9318.full
  61. jneuroinflammation.biomedcentral.com jneuroinflammation.biomedcentral.com
    Lipocalin 2 contributes to brain iron dysregulation but does not affect cognition, plaque load, and glial activation in the J20 Alzheimer mouse model
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    jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-018-1372-5
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24555
  63. Apr 2021
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer’s disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC8026112/
  65. Mar 2021
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ablating Adult Neural Stem Cells Improves Synaptic and Cognitive Functions in Alzheimer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC7897582/
  67. Sep 2020
  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24672
  69. Aug 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Cerebral Blood Volume under Normobaric Hyperoxia in the J20-hAPP Mouse Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC7200762/
  71. Nov 2017
  72. www.cell.com www.cell.com
    Amyloid β Is Not the Major Factor Accounting for Impaired Adult Hippocampal Neurogenesis in Mice Overexpressing Amyloid Precursor Protein
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    cell.com/stem-cell-reports/pdfExtended/S2213-6711(16)30186-2
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasma Exosomes Spread and Cluster Around β-Amyloid Plaques in an Animal Model of Alzheimer’s Disease
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    ncbi.nlm.nih.gov/pmc/articles/PMC5285341/