109 Matching Annotations
  1. Last 7 days
  2. 52.53.155.43 52.53.155.43
    JNEUROSCI.1563-23.2024.full (1)-html.html
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    1. scibot 26 Apr 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1523/jneurosci.1563-23.2024

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    52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Protocol for evaluating mutualistic cooperative behavior in mice using a water-reward task assay
    1
    1. scibot 23 Apr 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.xpro.2024.103023

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    sciencedirect.com/science/article/pii/S2666166724001886
  5. www.jneurosci.org www.jneurosci.org
    Super-Resolution Ultrasound Reveals Cerebrovascular Impairment in a Mouse Model of Alzheimer's Disease
    1
    1. scibot 10 Apr 2024
      034840-JAX

      DOI: 10.1523/JNEUROSCI.1251-23.2024

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    jneurosci.org/content/44/9/e1251232024
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease
    1
    1. scibot 03 Apr 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1002/jnr.24829

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24829
  7. alz-journals.onlinelibrary.wiley.com alz-journals.onlinelibrary.wiley.com
    Silencing Apoe with divalent-siRNAs improves amyloid burden and activates immune response pathways in Alzheimer's disease
    1
    1. scibot 02 Apr 2024
      34840-JAX

      DOI: 10.1002/alz.13703

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    alz-journals.onlinelibrary.wiley.com/doi/full/10.1002/alz.13703
  8. www.biorxiv.org www.biorxiv.org
    Increasing the vitamin C transporter SVCT2 in microglia improves synaptic plasticity and restrains memory impairments in Alzheimer’s disease models
    1
    1. scibot 01 Apr 2024
      34840

      DOI: 10.1101/2024.02.29.582679

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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    biorxiv.org/content/10.1101/2024.02.29.582679v1
  9. Mar 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytokine expression patterns predict suppression of vulnerable neural circuits in a mouse model of Alzheimer’s disease
    1
    1. scibot 31 Mar 2024
      034840-JAX

      DOI: 10.1101/2024.03.17.585383

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    ncbi.nlm.nih.gov/pmc/articles/PMC10979954/
  11. www.nature.com www.nature.com
    TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models
    1
    1. scibot 31 Mar 2024
      MMRRC Stock no. 034840

      DOI: 10.1038/s41593-024-01610-w

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    nature.com/articles/s41593-024-01610-w
  12. www.sciencedirect.com www.sciencedirect.com
    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
    2
    1. scibot 21 Mar 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.neuron.2024.02.017

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    2. scibot 21 Mar 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.neuron.2024.02.017

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    sciencedirect.com/science/article/pii/S0896627324001272
  13. www.sciencedirect.com www.sciencedirect.com
    Type-I-interferon-responsive microglia shape cortical development and behavior
    2
    1. scibot 15 Mar 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.cell.2024.02.020

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    2. scibot 15 Mar 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.cell.2024.02.020

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    sciencedirect.com/science/article/pii/S0092867424001867
  14. www.biorxiv.org www.biorxiv.org
    Identification of robust cellular programs using reproducible LDA that impact sex-specific disease progression in different genotypes of a mouse model of AD
    1
    1. scibot 09 Mar 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1101/2024.02.26.582178

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    biorxiv.org/content/10.1101/2024.02.26.582178v1
  15. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer’s disease brains
    1
    1. scibot 08 Mar 2024
      34840

      DOI: 10.1186/s13024-021-00464-1

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @Naa003

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      RRID:MMRRC_034840-JAX RRIDCUR:Missing
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    molecularneurodegeneration.biomedcentral.com/article/10.1186/s13024-021-00464-1
  16. Feb 2024
  17. content.iospress.com content.iospress.com
    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
    2
    1. scibot 16 Feb 2024
      RRID: MMRRC_034840-MU

      DOI: 10.3233/JAD-221058

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @abever99

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      RRID:MMRRC_034840-JAX
    2. scibot 16 Feb 2024
      RRID:MMRRC_034840-MU

      DOI: 10.3233/JAD-221058

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @abever99

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      RRID:MMRRC_034840-JAX RRIDCUR:Unresolved
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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221058
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice
    1
    1. scibot 16 Feb 2024
      RRID:MMRRC_034840-JAX

      DOI: 10.1172/JCI171468

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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      RRID:MMRRC_034840-JAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10866656/
  19. www.sciencedirect.com www.sciencedirect.com
    Clearance of β-amyloid and synapses by the optogenetic depolarization of microglia is complement selective
    1
    1. scibot 02 Feb 2024
      The Jackson LaboratoryStock No: 034840

      DOI: 10.1016/j.neuron.2023.12.003

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @evieth

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      RRID:MMRRC_034840-JAX
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    sciencedirect.com/science/article/pii/S0896627323009315
  20. Jan 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Alterations in Alzheimer's disease microglia transcriptome might be involved in bone pathophysiology
    1
    1. scibot 17 Jan 2024
      MMRRC Strain #034840-JAX

      DOI: 10.1016/j.nbd.2024.106404

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @bandrow

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      RRID:MMRRC_034840-JAX
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    sciencedirect.com/science/article/pii/S0969996124000032
  22. www.sciencedirect.com www.sciencedirect.com
    A cell therapy approach to restore microglial Trem2 function in a mouse model of Alzheimer’s disease
    1
    1. scibot 04 Jan 2024
      034840-JAX

      DOI: 10.1016/j.stem.2023.07.006

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @bandrow

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      RRID:MMRRC_034840-JAX
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    sciencedirect.com/science/article/pii/S1934590923002515
  23. www.eneuro.org www.eneuro.org
    Chronic Visual Stimulation with LED Light Flickering at 24, 40, or 80 Hz Failed to Reduce Amyloid β Load in the 5XFAD Alzheimer’s Disease Mouse Model
    1
    1. scibot 03 Jan 2024
      MMRRC #34 840-JAX

      DOI: 10.1523/ENEURO.0189-23.2023

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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    eneuro.org/content/10/8/ENEURO.0189-23.2023
  24. link.springer.com link.springer.com
    Beta-2 adrenergic receptor agonism alters astrocyte phagocytic activity and has potential applications to psychiatric disease
    1
    1. scibot 03 Jan 2024
      034840-JAX

      DOI: 10.1007/s44192-023-00050-5

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      RRID:MMRRC_034840-JAX
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    link.springer.com/article/10.1007/s44192-023-00050-5
  25. www.nature.com www.nature.com
    A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
    1
    1. scibot 03 Jan 2024
      034840-JAX

      DOI: 10.1038/s41593-022-01240-0

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      RRID:MMRRC_034840-JAX
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    nature.com/articles/s41593-022-01240-0
  26. www.mdpi.com www.mdpi.com
    Alteration of Neural Network and Hippocampal Slice Activation through Exosomes Derived from 5XFAD Nasal Lavage Fluid
    1
    1. scibot 03 Jan 2024
      34840-JAX

      DOI: 10.3390/ijms241814064

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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      RRID:MMRRC_034840-JAX
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    mdpi.com/1422-0067/24/18/14064
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Degradation of NLRP3 by p62-dependent-autophagy improves cognitive function in Alzheimer's disease by maintaining the phagocytic function of microglia
    1
    1. scibot 02 Jan 2024
      34840-JAX

      DOI: 10.1111/cns.14219

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @bandrow

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    onlinelibrary.wiley.com/doi/full/10.1111/cns.14219
  28. www.sciencedirect.com www.sciencedirect.com
    Amyloid Deposition and Dendritic Complexity of Corticocortical Projection Cells in Five Familial Alzheimer's Disease Mouse
    1
    1. scibot 02 Jan 2024
      034840-JAX

      DOI: 10.1016/j.neuroscience.2022.12.013

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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      RRID:MMRRC_034840-JAX
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    sciencedirect.com/science/article/pii/S0306452222006212
  29. preprints.opticaopen.org preprints.opticaopen.org
    Adaptive vessel tracing and segmentation in OCT enables robust detection of wall-to-lumen ratio abnormalities in 5xFAD mice
    1
    1. scibot 02 Jan 2024
      (MMRRC Stock No. 34840-JAX; Jackson Laboratory

      DOI: 10.1364/opticaopen.24038502.v1

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      RRID:MMRRC_034840-JAX
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    preprints.opticaopen.org/articles/preprint/Adaptive_vessel_tracing_and_segmentation_in_OCT_enables_robust_detection_of_wall-to-lumen_ratio_abnormalities_in_5xFAD_mice/24038502
  30. link.springer.com link.springer.com
    Comparison of Neuroinflammation Induced by Hyperphosphorylated Tau Protein Versus Ab42 in Alzheimer’s Disease
    2
    1. scibot 02 Jan 2024
      B6SJL-Tg (APPSwFlLon, PSEN1* M146L* L286V) 6799Vas/Mmjax

      DOI: 10.1007/s12035-023-03822-w

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @bandrow

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      RRID:MMRRC_034840-JAX
    2. scibot 02 Jan 2024
      MMRRC stock #34840

      DOI: 10.1007/s12035-023-03822-w

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      RRID:MMRRC_034840-JAX
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    link.springer.com/article/10.1007/s12035-023-03822-w
  31. www.sciencedirect.com www.sciencedirect.com
    Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice
    1
    1. scibot 02 Jan 2024
      34840

      DOI: 10.1016/j.bbih.2023.100663

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    sciencedirect.com/science/article/pii/S2666354623000777
  32. Dec 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abnormal [18F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer’s disease: In vivo PET/CT imaging studies of α4β2* nicotinic acetylcholinergic receptors and in vitro correlations with Aβ plaques
    1
    1. scibot 31 Dec 2023
      MMRRC stock#34840

      DOI: 10.1002/syn.22265

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    ncbi.nlm.nih.gov/pmc/articles/PMC10148164/
  34. Oct 2023
  35. www.biorxiv.org www.biorxiv.org
    Piezo1 agonist restores meningeal lymphatic vessels, drainage, and brain-CSF perfusion in craniosynostosis and aged mice
    1
    1. scibot 14 Oct 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1101/2023.09.27.559761

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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    biorxiv.org/content/10.1101/2023.09.27.559761v1
  36. Sep 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Tracking cell-type-specific temporal dynamics in human and mouse brains
    1
    1. scibot 30 Sep 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.cell.2023.08.042

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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    sciencedirect.com/science/article/pii/S0092867423009765
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep–wake Disturbances in AD Mice
    1
    1. scibot 06 Sep 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1523/JNEUROSCI.2124-22.2023

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

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    ncbi.nlm.nih.gov/pmc/articles/PMC10476643/
  39. Jun 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sex differences in the molecular signature of the developing mouse hippocampus
    2
    1. scibot 10 Jun 2023
      RRID:IMSR_JAX:006554

      DOI: 10.1186/s12864-017-3608-7

      Resource: (MMRRC Cat# 034840-JAX,RRID:MMRRC_034840-JAX)

      Curator: @evieth

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      RRIDCUR:Incorrect RRID:MMRRC_034840-JAX RRIDCUR:Unresolved
    2. scibot 09 Jun 2023
      IMSR_JAX:006554

      DOI: 10.1186/s12864-017-3608-7

      Resource: IMSR_JAX:006554

      Curator: @chewbeccax

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      RRID:MMRRC_034840-JAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC5356301/
  41. www.mdpi.com www.mdpi.com
    Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice
    1
    1. scibot 09 Jun 2023
      34840

      DOI: 10.3390/biom12030399

      Resource: MMRRC:034840-JAX

      Curator: @Naa003

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      RRIDCUR:Missing RRID:MMRRC_034840-JAX
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    mdpi.com/2218-273X/12/3/399
  42. content.iospress.com content.iospress.com
    Parvalbumin-Positive Neuron Loss and Amyloid-β Deposits in the Frontal Cortex of Alzheimer’s Disease-Related Mice
    2
    1. scibot 09 Jun 2023
      Jackson Laboratory Stock No. 006554

      DOI: 10.3233/JAD-181190

      Resource: IMSR_JAX:006554

      Curator: @bandrow

      SciCrunch record: RRID:IMSR_JAX:006554

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      RRIDCUR:Unrecognized RRID:MMRRC_034840-JAX
    2. scibot 09 Jun 2023
      MMRRC Stock No. 34840-JAX

      DOI: 10.3233/JAD-181190

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad181190
  43. May 2023
  44. www.mdpi.com www.mdpi.com
    Optical Redox Imaging of Ex Vivo Hippocampal Tissue Reveals Age-Dependent Alterations in the 5XFAD Mouse Model of Alzheimer’s Disease
    1
    1. scibot 06 May 2023
      MMRRC stock #34840

      DOI: 10.3390/metabo12090786

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    mdpi.com/2218-1989/12/9/786/htm
  45. genomemedicine.biomedcentral.com genomemedicine.biomedcentral.com
    PLCG2 is associated with the inflammatory response and is induced by amyloid plaques in Alzheimer’s disease
    1
    1. scibot 06 May 2023
      34840-JAX

      DOI: 10.1186/s13073-022-01022-0

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    genomemedicine.biomedcentral.com/articles/10.1186/s13073-022-01022-0
  46. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 05 May 2023
      JAX MMRRC Stock# 034840

      DOI: 10.1111/bph.15478

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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.15478
  47. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease
    1
    1. scibot 05 May 2023
      34840-JAX

      DOI: 10.1111/acel.13380

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    onlinelibrary.wiley.com/doi/full/10.1111/acel.13380
  48. Apr 2023
  49. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Degradation of Bone Quality in a Transgenic Mouse Model of Alzheimer′s Disease
    1
    1. scibot 29 Apr 2023
      34840-JAX

      DOI: 10.1002/jbmr.4723

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    asbmr.onlinelibrary.wiley.com/doi/full/10.1002/jbmr.4723
  50. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Longitudinal study of sub-regional cerebral viscoelastic properties of 5XFAD Alzheimer's disease mice using multifrequency MR elastography
    1
    1. scibot 29 Apr 2023
      JAX MMRRC Stock# 034840

      DOI: 10.1002/mrm.28709

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  51. www.science.org www.science.org
    Simultaneous Fe2+/Fe3+ imaging shows Fe3+ over Fe2+ enrichment in Alzheimer’s disease mouse brain
    1
    1. scibot 27 Apr 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1126/sciadv.ade7622

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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Simultaneous Fe2+/Fe3+ imaging shows Fe3+ over Fe2+ enrichment in Alzheimer’s disease mouse brain
    1
    1. scibot 27 Apr 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1126/sciadv.ade7622

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115418/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reduction of human Alzheimer’s disease risk and reversal of mouse model cognitive deficit with nucleoside analog use
    1
    1. scibot 11 Apr 2023
      MMRRC Strain #034840-JAX

      DOI: 10.1101/2023.03.17.23287375

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  54. Mar 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Extracellular vesicles derived from inflammatory-educated stem cells reverse brain inflammation—implication of miRNAs
    1
    1. scibot 23 Mar 2023
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    sciencedirect.com/science/article/pii/S1525001621004020
  56. www.biorxiv.org www.biorxiv.org
    Silencing of ApoE with Divalent siRNAs Drives Activation of Immune Clearance Pathways and Improves Amyloid Pathology in Mouse Models of Alzheimer’s Disease
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      MMRRC Stock No: 34840-JAX

      DOI: 10.1101/2022.06.28.498012

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  57. www.science.org www.science.org
    Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis
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    1. scibot 21 Mar 2023
      34840

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  58. www.biorxiv.org www.biorxiv.org
    Super-resolution ultrasound imaging of cerebrovascular impairment in a mouse model of Alzheimer’s disease
    1
    1. scibot 21 Mar 2023
      MMRRC Strain # 034840-JAX

      DOI: 10.1101/2022.10.05.511008

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  59. www.mdpi.com www.mdpi.com
    Enhanced Anxiety and Olfactory Microglial Activation in Early-Stage Familial Alzheimer’s Disease Mouse Model
    1
    1. scibot 21 Mar 2023
      34840-JAX

      DOI: 10.3390/biology11060938

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  60. link.springer.com link.springer.com
    SIRT3 Regulates Neuronal Excitability of Alzheimer’s Disease Models in an Oxidative Stress-Dependent Manner
    1
    1. scibot 17 Mar 2023
      34840-JAX

      DOI: 10.1007/s12017-021-08693-9

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    link.springer.com/article/10.1007/s12017-021-08693-9
  61. www.sciencedirect.com www.sciencedirect.com
    APOE modulates microglial immunometabolism in response to age, amyloid pathology, and inflammatory challenge
    1
    1. scibot 11 Mar 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.celrep.2023.112196

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    sciencedirect.com/science/article/pii/S2211124723002073
  62. Feb 2023
  63. www.sciencedirect.com www.sciencedirect.com
    The application of alcian blue to identify astrocyte-associated amyloid plaques by using fluorescence and confocal microscopy
    1
    1. scibot 07 Feb 2023
      MMRRC Stock No: 34840-JAX

      DOI: 10.1016/j.jneumeth.2023.109797

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  64. www.biorxiv.org www.biorxiv.org
    Alteration of neural network and hippocampal slice activation through exosomes derived from 5XFAD nasal lavage fluid
    1
    1. scibot 07 Feb 2023
      MMRRC Stock No: 34840-JAX

      DOI: 10.1101/2023.01.24.525465

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  65. Jan 2023
  66. www.sciencedirect.com www.sciencedirect.com
    Ikzf1 as a novel regulator of microglial homeostasis in inflammation and neurodegeneration
    1
    1. scibot 27 Jan 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.bbi.2023.01.016

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    sciencedirect.com/science/article/pii/S0889159123000223
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase inhibitors mitigate antipsychotic risperidone-induced motor side effects in aged mice and in a mouse model of Alzheimer’s disease
    1
    1. scibot 25 Jan 2023
      RRID:MMRRC_034840-JAX

      DOI: 10.3389/fpsyt.2022.1020831

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  68. www.sciencedirect.com www.sciencedirect.com
    Functional characterization of the dural sinuses as a neuroimmune interface
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    1. scibot 18 Jan 2023
      MMRRC 34840-JAX

      DOI: 10.1016/j.cell.2020.12.040

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    sciencedirect.com/science/article/pii/S0092867420317621
  69. Nov 2022
  70. www.sciencedirect.com www.sciencedirect.com
    Microglial Piezo1 senses Aβ fibril stiffness to restrict Alzheimer’s disease
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    1. scibot 11 Nov 2022
      MMRRC_034840

      DOI: 10.1016/j.neuron.2022.10.021

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  71. www.sciencedirect.com www.sciencedirect.com
    The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer’s disease
    1
    1. scibot 09 Nov 2022
      RRID:MMRRC_034840-MU

      DOI: 10.1016/j.neulet.2022.136958

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  72. Oct 2022
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased KIF11/Kinesin-5 expression offsets Alzheimer Aβ-mediated toxicity and cognitive dysfunction
    1
    1. scibot 27 Oct 2022
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.isci.2022.105288

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  74. www.sciencedirect.com www.sciencedirect.com
    SYK coordinates neuroprotective microglial responses in neurodegenerative disease
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      034840

      DOI: 10.1016/j.cell.2022.09.030

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  75. Apr 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective Regional Loss of Cortical Synapses Lacking Presynaptic Mitochondria in the 5xFAD Mouse Model
    1
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      34840-JAX

      DOI: 10.3389/fnana.2021.690168

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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated Expression of MiR-17 in Microglia of Alzheimer’s Disease Patients Abrogates Autophagy-Mediated Amyloid-β Degradation
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      MMRRC stock #34840

      DOI: 10.3389/fimmu.2021.705581

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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Practical considerations for choosing a mouse model of Alzheimer’s disease
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      MMRRC 34840-JAX

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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A1 restores cerebrovascular integrity concomitant with reduced amyloid-β and tau pathology
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      MMRRC Stock # 034840

      DOI: 10.1093/brain/awab050

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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Computer-Based Drug Design of Positive Modulators of Store-Operated Calcium Channels to Prevent Synaptic Dysfunction in Alzheimer’s Disease
    1
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      MMRRC Stock No: 34840-JAX

      DOI: 10.3390/ijms222413618

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  81. Mar 2022
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglial VPS35 deficiency impairs Aβ phagocytosis and Aβ-induced disease-associated microglia, and enhances Aβ associated pathology
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      MMRRC Stock No: 34840-JAX

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Meridianins Rescue Cognitive Deficits, Spine Density and Neuroinflammation in the 5xFAD Model of Alzheimer’s Disease
    1
    1. scibot 21 Mar 2022
      MMRRC catalog #034840-JAX

      DOI: 10.3389/fphar.2022.791666

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  84. Jan 2022
  85. www.nature.com www.nature.com
    Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence
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      MMRRC stock #34 840-JAX

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  86. Nov 2021
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s disease
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    1. scibot 29 Nov 2021
      34840-JAX

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  88. www.science.org www.science.org
    Deletion of Abi3 gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis
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    1. scibot 29 Nov 2021
      MMRRC) 34840

      DOI: 10.1126/sciadv.abe3954

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  89. Oct 2021
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preparing Viable Hippocampal Slices from Adult Mice for the Study of Sharp Wave-ripples
    1
    1. scibot 06 Oct 2021
      RRID:MMRRC_034840-JAX

      DOI: 10.21769/BioProtoc.3771

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    ncbi.nlm.nih.gov/pmc/articles/PMC7842787/
  91. Aug 2021
  92. www.spiedigitallibrary.org www.spiedigitallibrary.org
    Concurrent OCT and OCT angiography of retinal neurovascular degeneration in the 5XFAD Alzheimer’s disease mice
    1
    1. scibot 13 Aug 2021
      MMRRC Stock No. 34840-JAX

      DOI: 10.1117/1.NPh.8.3.035002

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    spiedigitallibrary.org/journals/neurophotonics/volume-8/issue-3/035002/Concurrent-OCT-and-OCT-angiography-of-retinal-neurovascular-degeneration-in/10.1117/1.NPh.8.3.035002.full
  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      RRID:MMRRC_034840-JAX

      DOI: 10.1002/cne.24551

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.24551
  94. Jul 2021
  95. www.nature.com www.nature.com
    Non-invasive in vivo hyperspectral imaging of the retina for potential biomarker use in Alzheimer’s disease
    1
    1. scibot 31 Jul 2021
      MMRRC Stock 34840-JAX

      DOI: 10.1038/s41467-019-12242-1

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    nature.com/articles/s41467-019-12242-1
  96. www.sciencedirect.com www.sciencedirect.com
    The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice
    1
    1. scibot 31 Jul 2021
      RRID:MMRRC-034840-JAX

      DOI: 10.1016/j.chembiol.2018.10.013

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    sciencedirect.com/science/article/pii/S2451945618303465
  97. www.sciencedirect.com www.sciencedirect.com
    TET2 Regulates the Neuroinflammatory Response in Microglia
    1
    1. scibot 29 Jul 2021
      The Jackson LaboratoryCat.# 34840-JAX

      DOI: 10.1016/j.celrep.2019.09.013

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    sciencedirect.com/science/article/pii/S2211124719311908
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of the dual orexin receptor antagonist DORA-22 on sleep in 5XFAD mice
    1
    1. scibot 29 Jul 2021
      B6SJL-Tg(APPSwFlLon, PSEN1*M146 L*L286V)6799Vas/Mmjax

      DOI: 10.1016/j.trci.2019.01.003

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    ncbi.nlm.nih.gov/pmc/articles/PMC6396100/
  99. www.nature.com www.nature.com
    Neutrophil adhesion in brain capillaries reduces cortical blood flow and impairs memory function in Alzheimer’s disease mouse models
    1
    1. scibot 28 Jul 2021
      MMRRC Stock No: 34840-JAX

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    nature.com/articles/s41593-018-0329-4
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MouseBytes, an open-access high-throughput pipeline and database for rodent touchscreen-based cognitive assessment
    2
    1. scibot 27 Jul 2021
      RRID:MGI:034840-JAX

      DOI: 10.7554/eLife.49630

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      RRID:MGI:101045-JAX

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    ncbi.nlm.nih.gov/pmc/articles/PMC6934379/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      MMRRC:34840

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    ncbi.nlm.nih.gov/pmc/articles/PMC6508668/
  102. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
    Alzheimer's Disease-Associated β-Amyloid Is Rapidly Seeded by Herpesviridae to Protect against Brain Infection.
    1
    1. scibot 27 Jul 2021
      RRID:MMRRC_0348

      DOI: 10.1016/j.neuron.2018.06.030

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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6075814/
  103. www.sciencedirect.com www.sciencedirect.com
    An optimized method for enrichment of whole brain-derived extracellular vesicles reveals insight into neurodegenerative processes in a mouse model of Alzheimer’s disease
    1
    1. scibot 27 Jul 2021
      JAX:006554

      DOI: 10.1016/j.jneumeth.2018.05.022

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    sciencedirect.com/science/article/pii/S0165027018301602
  104. www.sciencedirect.com www.sciencedirect.com
    In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain
    1
    1. scibot 03 Jul 2021
      RRID:IMSR_JAX:34840

      DOI: 10.1016/j.xpro.2021.100638

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    sciencedirect.com/science/article/pii/S2666166721003452
  105. Jun 2021
  106. www.nature.com www.nature.com
    RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease
    1
    1. scibot 22 Jun 2021
      RRID:MMRRC_034840-JAX

      DOI: 10.1038/s41419-021-03899-y

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    nature.com/articles/s41419-021-03899-y
  107. www.sciencedirect.com www.sciencedirect.com
    C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
    1
    1. scibot 17 Jun 2021
      MMRRC Stock No: 34840

      DOI: 10.1016/j.neuron.2021.05.020

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    sciencedirect.com/science/article/pii/S0896627321003731
  108. May 2021
  109. www.sciencedirect.com www.sciencedirect.com
    White matter aging drives microglial diversity
    1
    1. scibot 08 May 2021
      RRID:MMRRC_034840-JAX

      DOI: 10.1016/j.neuron.2021.01.027

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    sciencedirect.com/science/article/pii/S0896627321000738
  110. Mar 2021
  111. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Extracellular signal‐regulated kinase regulates microglial immune responses in Alzheimer’s disease
    1
    1. scibot 24 Mar 2021
      RRID:MMRRC_034840-JAX

      DOI: 10.1002/jnr.24829

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24829
  112. Feb 2021
  113. link.springer.com link.springer.com
    Increased levels of Stress-inducible phosphoprotein-1 accelerates amyloid-β deposition in a mouse model of Alzheimer’s disease
    1
    1. scibot 24 Feb 2021
      RRID:MGI:034840-JAX

      DOI: 10.1186/s40478-020-01013-5

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    link.springer.com/article/10.1186/s40478-020-01013-5
  114. Dec 2020
  115. www.nature.com www.nature.com
    Negative feedback control of neuronal activity by microglia
    1
    1. scibot 31 Dec 2020
      034840-JAX

      DOI: 10.1038/s41586-020-2777-8

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    nature.com/articles/s41586-020-2777-8
  116. www.sciencedirect.com www.sciencedirect.com
    Resveratrol confers neuroprotection against high-fat diet in a mouse model of Alzheimer's disease via modulation of proteolytic mechanisms
    1
    1. scibot 31 Dec 2020
      MMRRC stock #34840

      DOI: 10.1016/j.jnutbio.2020.108569

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    sciencedirect.com/science/article/pii/S095528632030601X
  117. www.sciencedirect.com www.sciencedirect.com
    ATUM-FIB microscopy for targeting and multiscale imaging of rare events in mouse cortex
    1
    1. scibot 31 Dec 2020
      MMRRCStock# 34840-JAX

      DOI: 10.1016/j.xpro.2020.100232

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    sciencedirect.com/science/article/pii/S2666166720302197
  118. onlinelibrary.wiley.com onlinelibrary.wiley.com
    RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease
    1
    1. scibot 31 Dec 2020
      To investigate

      DOI: 10.1111/nan.12686

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    onlinelibrary.wiley.com/doi/10.1111/nan.12686
  119. Sep 2020
  120. www.nature.com www.nature.com
    Transcriptome Profile of Nicotinic Receptor-Linked Sensitization of Beta Amyloid Neurotoxicity
    1
    1. scibot 04 Sep 2020
      B6SJL-Tg (APPSwFlLOn, PS1 (PSEN1)*M146L*L286V) 6799Vas/Mmjax

      DOI: 10.1038/s41598-020-62726-0

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    nature.com/articles/s41598-020-62726-0
  121. alzres.biomedcentral.com alzres.biomedcentral.com
    A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse
    1
    1. scibot 04 Sep 2020
      34840-JAX

      DOI: 10.1186/s13195-020-00617-2

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    alzres.biomedcentral.com/articles/10.1186/s13195-020-00617-2
  122. www.jneurosci.org www.jneurosci.org
    Inhibitory parvalbumin basket cell activity is selectively reduced during hippocampal sharp wave ripples in a mouse model of familial Alzheimer’s disease
    1
    1. scibot 03 Sep 2020
      RRID:MMRRC_034840-JAX

      DOI: 10.1523/JNEUROSCI.0425-20.2020

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    jneurosci.org/content/40/26/5116
  123. Aug 2020
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blood lactate dynamics in awake and anaesthetized mice after intraperitoneal and subcutaneous injections of lactate—sex matters
    1
    1. scibot 31 Aug 2020
      034840-JAX

      DOI: 10.7717/peerj.8328

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    ncbi.nlm.nih.gov/pmc/articles/PMC6951280/
  125. Jan 2020
  126. www.jneurosci.org www.jneurosci.org
    Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease
    1
    1. scibot 13 Jan 2020
      RRID:MMRRC_034840-JAX

      DOI: 10.1523/JNEUROSCI.2121-18.2019

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    jneurosci.org/content/39/13/2441
  127. Nov 2018
  128. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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      RRID:MMRRC_034840-JAX

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    onlinelibrary.wiley.com/doi/abs/10.1002/cne.24551
  129. molecularneurodegeneration.biomedcentral.com molecularneurodegeneration.biomedcentral.com
    BACE1 elevation engendered by GGA3 deletion increases β-amyloid pathology in association with APP elevation and decreased CHL1 processing in 5XFAD mice
    1
    1. scibot 05 Nov 2018
      34840-JAX

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    molecularneurodegeneration.biomedcentral.com/articles/10.1186/s13024-018-0239-7
  130. www.sciencedirect.com www.sciencedirect.com
    Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models
    1
    1. scibot 05 Nov 2018
      RRID:MMRRC_034840-JAX

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    sciencedirect.com/science/article/pii/S0896627318301016
  131. bmcneurosci.biomedcentral.com bmcneurosci.biomedcentral.com
    Solid lipid curcumin particles provide greater anti-amyloid, anti-inflammatory and neuroprotective effects than curcumin in the 5xFAD mouse model of Alzheimer’s disease
    1
    1. scibot 05 Nov 2018
      34840-JAX

      Curator: @bandrow

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    bmcneurosci.biomedcentral.com/articles/10.1186/s12868-018-0406-3
  132. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protection Against β‐Amyloid Neurotoxicity by a Non‐Toxic Endogenous N‐terminal β‐Amyloid Fragment and its Active Hexapeptide Core Sequence
    1
    1. scibot 05 Nov 2018
      RRID:MMRRC_034840-JAX

      Curator: @evieth

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14257/full
  133. Nov 2017
  134. www.sciencedirect.com www.sciencedirect.com
    Modulation of neuroinflammation and pathology in the 5XFAD mouse model of Alzheimer's disease using a biased and selective beta-1 adrenergic receptor partial agonist
    1
    1. scibot 08 Nov 2017
      MMRRC stock 034840

      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S0028390817300102
  135. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid‐β oligomers
    1
    1. scibot 08 Nov 2017
      RRID:MMRRC_034840-JAX

      Curator: @patriciaelyse_

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14118/full