78 Matching Annotations
  1. Oct 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Deciphering genomic evolution of metastatic organotropism with 535 paired primary lung cancers and metastases
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    sciencedirect.com/science/article/pii/S2211124725012203
  3. Sep 2025
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    Tracing metastatic spread in pediatric solid tumors using copy number and targeted deep sequencing
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    pathsocjournals.onlinelibrary.wiley.com/doi/10.1002/path.6472
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy of ATR Kinase Inhibitor Elimusertib Monotherapy or Combination in Tumors with DNA Damage Response Pathway and Other Genomic Alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402799/
  6. Aug 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intrahepatic Microbial Heterogeneity in Multifocal Hepatocellular Carcinoma and Its Association with Host Genomic and Transcriptomic Alterations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12319405/
  8. Jul 2025
  9. ascopubs.org ascopubs.org
    Clinical Significance of TERT Promoter Mutations in Neuroblastoma
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    ascopubs.org/doi/10.1200/PO-25-00074
  10. www.nature.com www.nature.com
    Shared genomic features of HIV+ diffuse large B-cell lymphoma in two African cohorts
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    nature.com/articles/s41598-025-10529-6
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and epigenomic analysis of plasma cell-free DNA identifies stemness features associated with worse survival in lethal prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11743868/
  12. Jun 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130809/
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    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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  15. May 2025
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    Auditory neuropathy spectrum disorder and related auditory features in patients with hearing loss associated with the MT-TS1 m.7471dup variant
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    sciencedirect.com/science/article/pii/S1567724925000534
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046333/
  18. Apr 2025
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Germline Pathogenic DROSHA Variants Are Linked to Pineoblastoma and Wilms Tumor Predisposition
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  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479818/
  21. Feb 2025
  22. 52.53.155.43 52.53.155.43
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    DNA methylation profiling identifies subgroups of lung adenocarcinoma with distinct immune cell composition, DNA methylation age, and clinical outcome
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    aacrjournals.org/clincancerres/article/28/17/3824/708062/DNA-Methylation-Profiling-Identifies-Subgroups-of
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    Whole genome sequencing powered ctDNA sequencing for breast cancer detection
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    sciencedirect.com/science/article/pii/S0923753425000535
  26. Jan 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting PRMT1 Reduces Cancer Persistence and Tumor Relapse in EGFR- and KRAS-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11747858/
  28. link.springer.com link.springer.com
    Sex disparities in the association between rare earth elements exposure and genetic mutation frequencies in lung cancer patients
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    link.springer.com/article/10.1038/s41598-024-79580-z
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    Ultrasensitive ctDNA detection for preoperative disease stratification in early-stage lung adenocarcinoma
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    link.springer.com/article/10.1038/s41591-024-03216-y
  30. 52.53.155.43 52.53.155.43
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  31. Dec 2024
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comprehensive genomic characterization of hematologic malignancies at a pediatric tertiary care center
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    pmc.ncbi.nlm.nih.gov/articles/PMC11647012/
  33. Nov 2024
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  35. Oct 2024
  36. aacrjournals.org aacrjournals.org
    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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  37. Sep 2024
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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  40. Jul 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrating Multisector Molecular Characterization into Personalized Peptide Vaccine Design for Patients with Newly Diagnosed Glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11215407/
  42. Jun 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumour microenvironment programming by an RNA–RNA-binding protein complex creates a druggable vulnerability in IDH-wild-type glioblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11178504/
  44. May 2024
  45. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Discovery of a novel potent EGFR inhibitor against EGFR activating mutations and on-target resistance in NSCLC
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    pubmed.ncbi.nlm.nih.gov/38330145/
  46. aacrjournals.org aacrjournals.org
    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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    aacrjournals.org/clincancerres/article/30/10/2272/745168/Integrative-Molecular-Analyses-of-the-MD-Anderson
  47. Mar 2024
  48. www.sciencedirect.com www.sciencedirect.com
    Follicular lymphoma B cells exhibit heterogeneous transcriptional states with associated somatic alterations and tumor microenvironments
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    sciencedirect.com/science/article/pii/S2666379124000661
  49. Feb 2024
  50. 52.53.155.43 52.53.155.43
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524949/
  52. Jan 2024
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  54. Dec 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  57. Nov 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Unveiling the metal mutation nexus: Exploring the genomic impacts of heavy metal exposure in lung adenocarcinoma and colorectal cancer
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    sciencedirect.com/science/article/pii/S0304389423018733
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618656/
  60. Oct 2023
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoantigen targetability in progressive advanced melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570682/
  62. 52.53.155.43 52.53.155.43
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  63. Sep 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying mechanisms of resistance by circulating tumour DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at time of PARP Inhibitor Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502468/
  65. Aug 2023
  66. 52.53.155.43 52.53.155.43
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  67. www.sciencedirect.com www.sciencedirect.com
    Early clonal extinction in glioblastoma progression revealed by genetic barcoding
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    sciencedirect.com/science/article/pii/S1535610823002416
  68. Jul 2023
  69. 52.53.155.43 52.53.155.43
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  70. Jun 2023
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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    ncbi.nlm.nih.gov/pmc/articles/PMC10281085/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10240575/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Efficacy and Whole Exome Sequencing of Liquid Biopsies in a Phase IB/II study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722539/
  74. Feb 2023
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A molecular phenotypic map of malignant pleural mesothelioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9881451/
  76. Jan 2023
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9853917/
  78. Aug 2022
  79. 52.53.155.43 52.53.155.43
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  80. Jul 2022
  81. www.sciencedirect.com www.sciencedirect.com
    Spatiotemporal genomic analysis reveals distinct molecular features in recurrent stage I non-small cell lung cancers
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    sciencedirect.com/science/article/pii/S2211124722008415
  82. Jun 2022
  83. aacrjournals.org aacrjournals.org
    Quantification of neoantigen-mediated immunoediting in cancer evolution
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    aacrjournals.org/cancerres/article/82/12/2226/699353/Quantification-of-Neoantigen-Mediated
  84. aacrjournals.org aacrjournals.org
    Cancer Stem Cells, not Bulk Tumor Cells, Determine Mechanisms of Resistance to SMO Inhibitors
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    aacrjournals.org/cancerrescommun/article/2/6/402/699311/Cancer-Stem-Cells-not-Bulk-Tumor-Cells-Determine
  85. aacrjournals.org aacrjournals.org
    Predictive markers of response to neoadjuvant durvalumab with nab-paclitaxel and dose dense doxorubicin/cyclophosphamide in basal-like triple negative breast cancer
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    aacrjournals.org/clincancerres/article/28/12/2587/699273/Predictive-Markers-of-Response-to-Neoadjuvant
  86. Apr 2022
  87. aacrjournals.org aacrjournals.org
    Bone marrow surveillance of pediatric cancer survivors identifies clones that predict therapy-related leukemia
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    aacrjournals.org/clincancerres/article/28/8/1614/694144/Bone-Marrow-Surveillance-of-Pediatric-Cancer
  88. Feb 2022
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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    ncbi.nlm.nih.gov/pmc/articles/PMC8828877/
  90. Dec 2021
  91. www.sciencedirect.com www.sciencedirect.com
    Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight
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    sciencedirect.com/science/article/pii/S266637912100344X
  92. Oct 2021
  93. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Prediction of Immunotherapy Response in Melanoma through Combined Modeling of Neoantigen Burden and Immune-Related Resistance Mechanisms
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    clincancerres.aacrjournals.org/content/27/15/4265
  94. Aug 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic characterization of de novo metastatic breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7887078/
  96. Jul 2021
  97. www.sciencedirect.com www.sciencedirect.com
    Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
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    Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
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  99. Mar 2021
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery
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    ncbi.nlm.nih.gov/pmc/articles/PMC7960510/
  101. Sep 2020
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    Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer
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  103. Jan 2020
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  105. Nov 2018
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    The Polyploid State Plays a Tumor-Suppressive Role in the Liver
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    Patient-Derived Xenografts for Prognostication and Personalized Treatment for Head and Neck Squamous Cell Carcinoma
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    sciencedirect.com/science/article/pii/S2211124718315675
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    Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
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  109. www.sciencedirect.com www.sciencedirect.com
    Integrated Genomic Analysis of Hürthle Cell Cancer Reveals Oncogenic Drivers, Recurrent Mitochondrial Mutations, and Unique Chromosomal Landscapes
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    Characterization of BK Polyomaviruses from Kidney Transplant Recipients Suggests a Role for APOBEC3 in Driving In-Host Virus Evolution
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    Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing
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  112. elifesciences.org elifesciences.org
    Untitled document
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    elifesciences.org/articles/31347
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    Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair
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    elifesciences.org/articles/32692
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    Genetic and Functional Drivers of Diffuse Large B Cell Lymphoma
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  115. Nov 2017
  116. www.sciencedirect.com www.sciencedirect.com
    Heterogeneous Tumor-Immune Microenvironments among Differentially Growing Metastases in an Ovarian Cancer Patient
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  117. www.sciencedirect.com www.sciencedirect.com
    Stage-Specific Human Induced Pluripotent Stem Cells Map the Progression of Myeloid Transformation to Transplantable Leukemia
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