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Oct 2025
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Mechanochemical waves in focal adhesions during cell migration

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1. scibot 08 Oct 2025
  
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  DOI: 10.1126/sciadv.adw6425
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12494029/
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Mechanochemical waves in focal adhesions during cell migration

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  DOI: 10.1126/sciadv.adw6425
  
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science.org/doi/10.1126/sciadv.adw6425
Aug 2025
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Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction

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1. scibot 15 Aug 2025
  
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sciencedirect.com/science/article/pii/S0969212625002655
Jul 2025
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41556_2025_1712_MOESM4_ESM-html.html

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52.53.155.43/e8133be4a6a5cba631389479a5d84b0633fcb0c3/41556_2025_1712_MOESM4_ESM-html.html
May 2025
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The molecular mechanisms of visual chromophore release from cellular retinaldehyde-binding protein

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1. scibot 22 May 2025
  
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sciencedirect.com/science/article/pii/S0969212625001741
Jan 2025
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Passage of the HIV capsid cracks the nuclear pore

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  DOI: 10.1016/j.cell.2024.12.008
  
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pdf-html.html

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52.53.155.43/c4b4123d391d07d10a2413d599331feb3e0a7994/pdf-html.html
Jul 2024
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A force-sensitive mutation reveals a non-canonical role for dynein in anaphase progression

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1. scibot 04 Jul 2024
  
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  DOI: 10.1083/jcb.202310022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11215527/
Apr 2024
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Structural basis of ligand specificity and channel activation in an insect gustatory receptor

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  DOI: 10.1016/j.celrep.2024.114035
  
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cell.com/cell-reports/fulltext/S2211-1247(24)00363-2
Aug 2023
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The design of functional proteins using tensorized energy calculations

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.crmeth.2023.100560
  
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sciencedirect.com/science/article/pii/S2667237523002047
May 2023
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High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter

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1. scibot 18 May 2023
  
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  DOI: 10.7554/eLife.84006
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10185341/
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Examining asymmetric pairwise pre-reaction and transition states in enzymatic catalysis by molecular dynamics simulation and quantum mechanics/molecular mechanics calculation

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1. scibot 04 May 2023
  
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  DOI: 10.1016/j.xpro.2023.102263
  
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sciencedirect.com/science/article/pii/S2666166723002216
Mar 2023
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Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation

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1. scibot 10 Mar 2023
  
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  DOI: 10.7554/eLife.86258
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9991059/
Feb 2023
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Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans

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1. scibot 18 Feb 2023
  
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  DOI: 10.1016/j.immuni.2023.01.027
  
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sciencedirect.com/science/article/pii/S1074761323000390
Jan 2023
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Mapping the FtsQBL divisome components in bacterial NTD pathogens as potential drug targets

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1. scibot 20 Jan 2023
  
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  DOI: 10.3389/fgene.2022.1010870
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9846249/
Oct 2022
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Ligand-induced shifts in conformational ensembles that describe transcriptional activation

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1. scibot 14 Oct 2022
  
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  DOI: 10.7554/eLife.80140
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9555869/
Feb 2022
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Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats

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1. scibot 08 Feb 2022
  
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  DOI: 10.7554/eLife.72908
  
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elifesciences.org/articles/72908
Oct 2021
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TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells

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1. scibot 02 Oct 2021
  
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  DOI: 10.7554/eLife.71474
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
Sep 2021
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A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites

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1. scibot 17 Sep 2021
  
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  DOI: 10.1016/j.str.2021.07.006
  
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sciencedirect.com/science/article/pii/S0969212621002562
Aug 2021
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Simulating PIP2-Induced Gating Transitions in Kir6.2 Channels

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1. scibot 27 Aug 2021
  
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  DOI: 10.3389/fmolb.2021.711975
  
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  DOI: 10.3389/fmolb.2021.711975
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8384051/
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Untitled document

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  DOI: 10.1016/j.molcel.2018.11.014
  
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sciencedirect.com/science/article/pii/S1097276518309845
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Untitled document

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  DOI: 10.1002/jcb.27636
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcb.27636
Jul 2021
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Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

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1. scibot 31 Jul 2021
  
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elifesciences.org/articles/47150
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A photoswitchable GABA receptor channel blocker

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1. scibot 29 Jul 2021
  
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  DOI: 10.1111/bph.14689
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14689
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Intrinsic Structural Features of the Human IRE1α Transmembrane Domain Sense Membrane Lipid Saturation

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1. scibot 28 Jul 2021
  
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sciencedirect.com/science/article/pii/S2211124719303249
Apr 2021
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Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

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1. scibot 23 Apr 2021
  
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  DOI: 10.1016/j.str.2021.04.001
  
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sciencedirect.com/science/article/pii/S0969212621001179
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A nexus of intrinsic dynamics underlies translocase priming

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Kinetic analysis of ASIC1a delineates conformational signaling from proton-sensing domains to the channel gate

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  DOI: 10.7554/eLife.66488
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8009679/
Mar 2021
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SARS-CoV-2 S protein:ACE2 interaction reveals novel allosteric targets

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ncbi.nlm.nih.gov/pmc/articles/PMC7932696/
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Pre-existing bilayer stresses modulate triglyceride accumulation in the ER versus lipid droplets

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  DOI: 10.7554/eLife.62886
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7895522/
Feb 2021
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The hitchhiker's guide to the periplasm: unexpected molecular interactions of polymyxin B1 in E. coli

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  DOI: 10.1016/j.str.2021.01.009
  
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cell.com/structure/abstract/S0969-2126(21)00009-5
Dec 2020
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Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts

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  DOI: 10.1016/j.celrep.2020.108534
  
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cell.com/cell-reports/fulltext/S2211-1247(20)31523-0
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Structural ordering of the Plasmodium berghei circumsporozoite protein repeats by inhibitory antibody 3D11

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  DOI: 10.7554/eLife.59018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7704109/
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The structures of secretory and dimeric immunoglobulin A

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1. scibot 09 Dec 2020
  
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  DOI: 10.7554/eLife.56098
  
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elifesciences.org/articles/56098
Nov 2020
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Conformational stability of the bacterial adhesin, FimH, with an inactivating mutation

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1. scibot 20 Nov 2020
  
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  DOI: 10.1002/prot.26013
  
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onlinelibrary.wiley.com/doi/10.1002/prot.26013
Oct 2020
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Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation

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  DOI: 10.7554/eLife.57680
  
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elifesciences.org/articles/57680
Sep 2020
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A CLC-ec1 mutant reveals global conformational change and suggests a unifying mechanism for the CLC Cl–/H+ transport cycle

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1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.53479
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7253180/
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β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery

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1. scibot 14 Sep 2020
  
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  DOI: 10.7554/eLife.51111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7041949/
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Local frustration determines loop opening during the catalytic cycle of an oxidoreductase

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1. scibot 09 Sep 2020
  
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  DOI: 10.7554/eLife.54661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7347389/
Jan 2020
elifesciences.org elifesciences.org

FcγRIIB-I232T polymorphic change allosterically suppresses ligand binding

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1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.46689
  
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elifesciences.org/articles/46689
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Rewiring Ancient Residue Interaction Networks Drove the Evolution of Specificity in Steroid Receptors

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.str.2019.11.012
  
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sciencedirect.com/science/article/pii/S096921261930396X
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Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.08.038
  
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sciencedirect.com/science/article/pii/S0092867419309572
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BPS Publications

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1. scibot 13 Jan 2020
  
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  DOI: 10.1111/bph.14693
  
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bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14693
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The Structural Basis for Low Conductance in the Membrane Protein VDAC upon β-NADH Binding and Voltage Gating

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1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.str.2019.11.015
  
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sciencedirect.com/science/article/pii/S0969212619304332
Nov 2018
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TMC1 Forms the Pore of Mechanosensory Transduction Channels in Vertebrate Inner Ear Hair Cells

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1. scibot 05 Nov 2018
  
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  Curator: @Jmenke
  
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sciencedirect.com/science/article/pii/S0896627318306317
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Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6056239/
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Structural and Dynamics Comparison of Thermostability in Ancient, Modern, and Consensus Elongation Factor Tus

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0969212617303726
elifesciences.org elifesciences.org

Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid

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1. scibot 05 Nov 2018
  
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  RRID:SCR_001820
  
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elifesciences.org/articles/28626
europepmc.org europepmc.org

Untitled document

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5716661/
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Malaria parasite LIMP protein regulates sporozoite gliding motility and infectivity in mosquito and mammalian hosts.

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5438254/