92 Matching Annotations
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    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12415682/
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    Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8
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    sciencedirect.com/science/article/pii/S2666979X2500237X
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    Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
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    aacrjournals.org/bloodcancerdiscov/article/6/5/450/764332/Mutagenic-Impact-and-Evolutionary-Influence-of
  5. Sep 2025
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380150/
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    Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses
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    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
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    GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction During Routine Tumor Profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399951/
  10. Jun 2025
  11. 52.53.155.43 52.53.155.43
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    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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  14. May 2025
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    Inferring Drug–Gene Relationships in Cancer Using Literature-Augmented Large Language Models
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  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046327/
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    Social, behavioral and clinical risk factors are associated with clonal hematopoiesis
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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534558/
  19. Apr 2025
  20. 52.53.155.43 52.53.155.43
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    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479818/
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    Establishing a comprehensive panel of patient-derived xenograft models for high-grade endometrial carcinoma: molecular subtypes, genetic alterations, and therapeutic target profiling
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    sciencedirect.com/science/article/pii/S1476558625000375
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    Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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  24. Mar 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes
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  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
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  27. Feb 2025
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    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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  29. aacrjournals.org aacrjournals.org
    Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis
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    aacrjournals.org/clincancerres/article/30/21/4887/749133/Multiomics-Profiling-Distinguishes-Sebaceous
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    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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  31. Jan 2025
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    Predisposition footprints in the somatic genome of Wilms tumours
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  34. 52.53.155.43 52.53.155.43
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  35. Dec 2024
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploiting NRF2-ARE pathway activation in papillary renal cell carcinoma
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    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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  38. Nov 2024
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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  40. Oct 2024
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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    aacrjournals.org/clincancerres/article/26/24/6494/82920/Clinical-Outcome-Related-Mutational-Signatures
  43. Sep 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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    Activating mTOR mutations are detrimental in nutrient-poor conditions
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  47. Aug 2024
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours
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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    Impact of rare structural variant events in newly diagnosed multiple myeloma
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  51. Jul 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebrospinal fluid cfDNA sequencing for classification of central nervous system glioma
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  53. Jun 2024
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  55. May 2024
  56. aacrjournals.org aacrjournals.org
    Negative hyperselection of resistance mutations for panitumumab maintenance in RAS wild-type metastatic colorectal cancer (PanaMa phase II trial, AIO KRK 0212)
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  58. Apr 2024
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Co-mutations and KRAS G12C inhibitor efficacy in advanced NSCLC
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  60. Mar 2024
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    A novel type of monocytic leukemia stem cell revealed by the clinical use of venetoclax-based therapy
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  62. Feb 2024
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    Active natural compounds perturb the melanoma risk-gene network
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    dx.doi.org/10.1093/g3journal/jkad274
  65. Jan 2024
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  67. Dec 2023
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  69. Nov 2023
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    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    dx.doi.org/10.1158/2767-9764.CRC-23-0165
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    Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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  72. Jul 2023
  73. www.nature.com www.nature.com
    The tumor suppressor CREBBP and the oncogene MYCN cooperate to induce malignant brain tumors in mice
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    nature.com/articles/s41389-023-00481-3
  74. Jun 2023
  75. www.sciencedirect.com www.sciencedirect.com
    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A platform for efficient establishment and drug-response profiling of high-grade serous ovarian cancer organoids
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    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I–associated peptides
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    ncbi.nlm.nih.gov/pmc/articles/PMC10236148/
  78. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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  79. May 2023
  80. 52.53.155.43 52.53.155.43
    The immunopeptidome from a genomic perspective: Establishing the non-canonical landscape of MHC class I-associated peptides.
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    Mutational Landscape of CEBPA in Mexican Pediatric Acute Myeloid Leukemia Patients: Prognostic Implications
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  82. Feb 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
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    A molecular phenotypic map of malignant pleural mesothelioma
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  85. Jan 2023
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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    Comparative Genomics Provides Etiologic and Biological Insight into Melanoma Subtypes
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  88. Dec 2022
  89. aacrjournals.org aacrjournals.org
    Treatment represents a key driver of metastatic cancer evolution
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    aacrjournals.org/cancerres/article/82/16/2918/707589/Treatment-Represents-a-Key-Driver-of-Metastatic
  90. Sep 2022
  91. f1000research.com f1000research.com
    F1000Research Article: Identification of prognostic biomarkers of invasive ductal carcinoma by an integrated bioinformatics approach.
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  92. Aug 2022
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  94. Jul 2022
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    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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  97. Jun 2022
  98. link.springer.com link.springer.com
    Serial Tumor Molecular Profiling of Newly Diagnosed HER2-Negative Breast Cancers During Chemotherapy in Combination with Angiogenesis Inhibitors
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    link.springer.com/article/10.1007/s11523-022-00886-x
  99. aacrjournals.org aacrjournals.org
    Predictive markers of response to neoadjuvant durvalumab with nab-paclitaxel and dose dense doxorubicin/cyclophosphamide in basal-like triple negative breast cancer
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    aacrjournals.org/clincancerres/article/28/12/2587/699273/Predictive-Markers-of-Response-to-Neoadjuvant
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Mutational Signature Comprehensive Analysis Toolkit (musicatk) for the discovery, prediction, and exploration of mutational signatures
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    ncbi.nlm.nih.gov/pmc/articles/PMC8639789/
  101. May 2022
  102. aacrjournals.org aacrjournals.org
    Single cell characterization of the cellular landscape of acral melanoma identifies novel targets for immunotherapy
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    aacrjournals.org/clincancerres/article/28/10/2131/694823/Single-cell-Characterization-of-the-Cellular
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconvoluting mechanisms of acquired resistance to RAF inhibitors in BRAF V600E mutant human glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8595717/
  104. aacrjournals.org aacrjournals.org
    A Phenogenetic Axis that Modulates Clinical Manifestation and Predicts Treatment Outcome in Primary Myeloid NeoplasmsLandscape of Myeloid Neoplasms in a Chinese Cohort
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    aacrjournals.org/cancerrescommun/article/2/4/258/694752/A-Phenogenetic-Axis-that-Modulates-Clinical
  105. Apr 2022
  106. f1000research.com f1000research.com
    F1000Research Article: IsoAligner: dynamic mapping of amino acid positions across protein isoforms.
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    f1000research.com/articles/11-382
  107. Dec 2021
  108. www.sciencedirect.com www.sciencedirect.com
    Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight
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    sciencedirect.com/science/article/pii/S266637912100344X
  109. Aug 2021
  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic characterization of de novo metastatic breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7887078/
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    Interaction between Ras and Src clones causes interdependent tumor malignancy via Notch signaling in Drosophila
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  112. Jul 2021
  113. europepmc.org europepmc.org
    A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.
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    europepmc.org/articles/PMC5764568/
  114. Jun 2021
  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen receptor α (ERα)-binding super-enhancers drive key mediators that control uterine estrogen responses in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7307205/
  116. May 2021
  117. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Bladder tumor subtype commitment occurs in carcinoma in-situ driven by key signaling pathways including ECM remodeling
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    cancerres.aacrjournals.org/content/81/6/1552
  118. www.sciencedirect.com www.sciencedirect.com
    Comprehensive analysis of genomic alterations, clinical outcomes, putative functions and potential therapeutic value of MMP11 in human breast cancer
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    sciencedirect.com/science/article/pii/S2452014420302661
  119. Apr 2021
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    Integrated Omics of Metastatic Colorectal Cancer
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    sciencedirect.com/science/article/pii/S153561082030413X
  121. Mar 2021
  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple-Negative Essential Thrombocythemia: Clinical-Pathological and Molecular Features. A Single-Center Cohort Study
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    ncbi.nlm.nih.gov/pmc/articles/PMC8006378/
  123. academic.oup.com academic.oup.com
    Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma
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  124. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  128. Nov 2018
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    Cell Model Passports—a hub for clinical, genetic and functional datasets of preclinical cancer models
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  130. Nov 2017
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    A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
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    A network of epigenetic modifiers and DNA repair genes controls tissue-specific copy number alteration preference
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