134 Matching Annotations
  1. Jul 2026
  2. aacrjournals.org aacrjournals.org
    Uniform processing of diverse sequencing data: A cross-population comparison of colon cancer genomic landscapes from The Cancer Genome Atlas and a Chinese cohort
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    aacrjournals.org/cebp/article/35/5/762/784356/Uniform-Processing-of-Diverse-Sequencing-Data-A
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Pan-Tumor Landscape of Gene Amplifications and Copy Number Amplification Ratio for Established and Emerging Clinical Targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320176/
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and immune landscape of recurrent and/or distant metastatic squamous cell carcinoma of the head and neck: an EORTC/IMMUCAN project
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320198/
  5. www.biorxiv.org www.biorxiv.org
    A comprehensive analysis of calreticulin mutants reveals distinct biophysicochemical proprieties with a potential for refined targeted therapies
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    biorxiv.org/content/10.64898/2026.06.19.733337v1
  6. Jun 2026
  7. aacrjournals.org aacrjournals.org
    Genomic and transcriptomic analysis of high-grade endometrial carcinoma reveals biological heterogeneity and molecular classification challenges
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    aacrjournals.org/cancerrescommun/article/6/4/961/784451/Genomic-and-Transcriptomic-Analysis-of-High-Grade
  8. aacrjournals.org aacrjournals.org
    The Impact of Concordance Between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the Rome Trial
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    aacrjournals.org/clincancerres/article/32/1/45/771258/The-Impact-of-Concordance-between-Liquid-and
  9. May 2026
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136883/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Out-of-frame CBX3::ALK fusion drives ALK activation and therapy response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130619/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genomically Tailored Multiagent Precision Medicine Clinical Trial for Adults with Recurrent Glioblastoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133611/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis–Derived Variants in Liquid Biopsies from Patients with Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133610/
  14. www.sciencedirect.com www.sciencedirect.com
    Tissue tension fosters macrophage-driven lipid peroxidation-induced DNA damage
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    sciencedirect.com/science/article/pii/S1535610826001765
  15. Apr 2026
  16. aacrjournals.org aacrjournals.org
    Functional analysis of rare RAS variants of unknown significance
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    aacrjournals.org/cancerrescommun/article/5/10/1747/766027/Functional-Analysis-of-Rare-RAS-Variants-of
  17. www.science.org www.science.org
    Patient-derived pediatric brain tumor orthotopic xenografts and tumor organoids faithfully recapitulate primary tumors
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    science.org/doi/10.1126/sciadv.aea4966
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mapping genomic heterogeneity in paediatric and adolescent-young adult sarcomas: insights from the Italian SAR-GEN2016 and SAR-GEN_ITA prospective multicenter trials
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    pmc.ncbi.nlm.nih.gov/articles/PMC13090861/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor genomics in patients younger than 40 years of age with metastatic breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13057355/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutational Signatures and Clonal Hematopoiesis in Intestinal Metaplasia across Countries with Varying Stomach Cancer Incidence
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056296/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamic and Ongoing De Novo L1 Retrotransposition Contributes to Genome Plasticity and Intrapatient Heterogeneity in Ovarian Cancer
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055634/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integration of Short- and Long-Read RNA Sequencing Enables the Discovery of Circular RNAs
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    pmc.ncbi.nlm.nih.gov/articles/PMC12776659/
  23. 54.241.53.176 54.241.53.176
    Integrating interferon gamma receptor pathways, antigenicity, and immune contexture as predictors of immunotherapeutic strategies for mucosal melanomas
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    54.241.53.176/3e63435d4731406bfcdb4ffda4d231800522dc1e/inline-supplementary-material-1-html.html
  24. Mar 2026
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acquired High Tumor Mutational Burden and Activity of Immunotherapy after Targeted Therapy in Microsatellite Stable Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012239/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Phase 2 Trial of Niraparib in Patients with Advanced Pancreatic Cancer Harboring Pathogenic Variants in ATM, BRCA1, BRCA2, PALB2, and CHEK2
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC13002239/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Germline predisposition to oncogenic alkylating damage in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12977196/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Metastatic progression of pheochromocytoma and paraganglioma occurs via parallel evolution
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12963421/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatially Discontinuous Mutation Topographies in Ductal Carcinoma in Situ Reveal Non-Competitive Growth Dynamics
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    pmc.ncbi.nlm.nih.gov/articles/PMC12950944/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12951107/
  31. Feb 2026
  32. www.biorxiv.org www.biorxiv.org
    Systematic functional drug testing in patient-derived models reveals ex vivo sensitivities associated with clinical outcome in rare solid tumors
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    biorxiv.org/content/10.64898/2026.02.18.705724v1
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Integrating circulating tumor DNA analysis and radiomics for dynamic risk assessment in localized lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12324966/
  34. Jan 2026
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lazertinib with stereotactic body radiotherapy in oligometastatic EGFR-mutant non-small-cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12874586/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinicogenomic characterization of inflammatory breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12255483/
  37. www.medrxiv.org www.medrxiv.org
    STK11 mutations and deletions define a distinct subtype of cervical adenocarcinoma
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    medrxiv.org/content/10.64898/2026.01.01.25343162v1
  38. www.nature.com www.nature.com
    Functional footprints of homologous recombination deficiency in prostate cancer revealed by ctDNA fragmentation and transcription factor accessibility
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    nature.com/articles/s41416-025-03301-0
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
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    pmc.ncbi.nlm.nih.gov/articles/PMC12748524/
  40. Dec 2025
  41. www.nature.com www.nature.com
    Personalized ctDNA detection and genomic profiling in the NeoRHEA Study
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    nature.com/articles/s41523-025-00852-6
  42. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Extrachromosomal circular miRNA-gene amplifications contribute to the renal cancer phenotype
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    sciencedirect.com:5037/science/article/pii/S2211124725014329
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cancer Genomic Alterations and Microenvironmental Features Encode Synergistic Interactions with Disease Outcomes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12670080/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term Survival and Molecular Biomarker Evaluation of a Phase II Cetuximab and Nivolumab Clinical Trial in Recurrent/Metastatic Head and Neck Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12667737/
  45. Nov 2025
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    DLBCL Cells Emerge after CD19 CAR T Cells with Cross-Antigen Resistance and a Gene Signature Predictive of Clinical CAR T-cell Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12591092/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dynamics of Mutant Hematopoietic Progenitor Cells Are Not Associated with Clinical Outcomes in Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12050965/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development and Application of MiMouse, a Comprehensive Genomic Profiling Panel for Credentialing Mouse Tumor Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12569591/
  49. Oct 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500237/
  51. Sep 2025
  52. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of DNA recognition by the HMG-box-C1 module of capicua
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    sciencedirect.com/science/article/pii/S0969212625003223
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of Sorting Nexin 10 accelerates KRAS-induced pancreatic tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12415682/
  54. www.sciencedirect.com www.sciencedirect.com
    Phenotypic pleiotropy of missense variants in human B cell confinement receptor P2RY8
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    sciencedirect.com/science/article/pii/S2666979X2500237X
  55. aacrjournals.org aacrjournals.org
    Mutagenic Impact and Evolutionary Influence of Chemoradiotherapy in Hematologic Malignancies
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    aacrjournals.org/bloodcancerdiscov/article/6/5/450/764332/Mutagenic-Impact-and-Evolutionary-Influence-of
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detection of human brain cancers using genomic and immune cell characterization of cerebrospinal fluid through CSF-BAM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12380150/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cemiplimab in locally advanced or metastatic secondary angiosarcomas (CEMangio): A phase II clinical trial and biomarker analyses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402795/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Plasma exosomes from individuals with type 2 diabetes drive breast cancer aggression in patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12381303/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GPSai: A Clinically Validated AI Tool for Tissue of Origin Prediction During Routine Tumor Profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12399951/
  60. Jun 2025
  61. 52.53.155.43 52.53.155.43
    PDF-html.html
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    52.53.155.43/40d57cf5e469615dd789036d1af2f800d0eb4416/PDF-html.html
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aged and BRCA-Mutated Stromal Cells Drive Epithelial Cell Transformation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130807/
  63. 52.53.155.43 52.53.155.43
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    52.53.155.43/c61ac68a2ef54dec5fc8920e4a9a98b5252e85ab/PDF-html.html
  64. May 2025
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inferring Drug–Gene Relationships in Cancer Using Literature-Augmented Large Language Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12036822/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prenatal Exposure to Chemotherapy Increases the Mutation Burden in Human Neonatal Hematopoietic Stem Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12046327/
  67. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Social, behavioral and clinical risk factors are associated with clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11530318/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The genomic landscape of benign and malignant thyroid tumors from individuals carrying germline PTEN variants is distinct from sporadic thyroid cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC11534558/
  69. Apr 2025
  70. 52.53.155.43 52.53.155.43
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  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Genomics-Driven Artificial Intelligence-Based Model Classifies Breast Invasive Lobular Carcinoma and Discovers CDH1 Inactivating Mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11479818/
  72. www.sciencedirect.com www.sciencedirect.com
    Establishing a comprehensive panel of patient-derived xenograft models for high-grade endometrial carcinoma: molecular subtypes, genetic alterations, and therapeutic target profiling
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    sciencedirect.com/science/article/pii/S1476558625000375
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic Profiling to Contextualize the Results of Intervention for Smoldering Multiple Myeloma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11444893/
  74. Mar 2025
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes
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    pmc.ncbi.nlm.nih.gov/articles/PMC11907192/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC11911804/
  77. Feb 2025
  78. www.sciencedirect.com www.sciencedirect.com
    Effect of MisMatch repair deficiency on metastasis occurrence in a syngeneic mouse model
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    sciencedirect.com/science/article/pii/S1476558625000247
  79. aacrjournals.org aacrjournals.org
    Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis
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    aacrjournals.org/clincancerres/article/30/21/4887/749133/Multiomics-Profiling-Distinguishes-Sebaceous
  80. www.cell.com www.cell.com
    Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy
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    cell.com/cell-stem-cell/fulltext/S1934-5909(25)00002-5
  81. Jan 2025
  82. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.17455
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Predisposition footprints in the somatic genome of Wilms tumours
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617291/
  84. 52.53.155.43 52.53.155.43
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  85. Dec 2024
  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Exploiting NRF2-ARE pathway activation in papillary renal cell carcinoma
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35311
  87. www.mdpi.com www.mdpi.com
    Pan-Cancer Insights: A Study of Microbial Metabolite Receptors in Malignancy Dynamics
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    mdpi.com/2072-6694/16/24/4178
  88. Nov 2024
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537923/
  90. Oct 2024
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443220/
  92. aacrjournals.org aacrjournals.org
    Clinical Outcome–Related Mutational Signatures Identified by Integrative Genomic Analysis in Nasopharyngeal Carcinoma
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    aacrjournals.org/clincancerres/article/26/24/6494/82920/Clinical-Outcome-Related-Mutational-Signatures
  93. Sep 2024
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416222/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393546/
  96. aacrjournals.org aacrjournals.org
    Activating mTOR mutations are detrimental in nutrient-poor conditions
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    aacrjournals.org/cancerres/article/82/18/3263/709030/Activating-mTOR-Mutations-Are-Detrimental-in
  97. Aug 2024
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTORC1-driven protein translation correlates with clinical benefit of capivasertib within a genetically preselected cohort of PIK3CA-altered tumours
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    ncbi.nlm.nih.gov/pmc/articles/PMC11320025/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11325147/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of rare structural variant events in newly diagnosed multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841766/
  101. Jul 2024
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebrospinal fluid cfDNA sequencing for classification of central nervous system glioma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11247324/
  103. Jun 2024
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  105. May 2024
  106. aacrjournals.org aacrjournals.org
    Negative hyperselection of resistance mutations for panitumumab maintenance in RAS wild-type metastatic colorectal cancer (PanaMa phase II trial, AIO KRK 0212)
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  107. 52.53.155.43 52.53.155.43
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  110. Mar 2024
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  115. Jan 2024
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  122. Jul 2023
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  124. Jun 2023
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  135. Jan 2023
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  138. Dec 2022
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  147. Jun 2022
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  151. May 2022
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  157. Dec 2021
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  159. Aug 2021
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  162. Jul 2021
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    A homozygous FANCM mutation underlies a familial case of non-syndromic primary ovarian insufficiency.
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  164. Jun 2021
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  166. May 2021
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    Bladder tumor subtype commitment occurs in carcinoma in-situ driven by key signaling pathways including ECM remodeling
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    Comprehensive analysis of genomic alterations, clinical outcomes, putative functions and potential therapeutic value of MMP11 in human breast cancer
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  169. Apr 2021
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  171. Mar 2021
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  174. Jan 2020
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    Mechanisms of Progression of Myeloid Preleukemia to Transformed Myeloid Leukemia in Children with Down Syndrome
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    A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
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  178. Nov 2018
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  180. Nov 2017
  181. elifesciences.org elifesciences.org
    A metabolic switch controls intestinal differentiation downstream of Adenomatous polyposis coli (APC)
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