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Jan 2025
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Protocol for live imaging of axonal transport in iPSC-derived iNeurons

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1. scibot 30 Jan 2025
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11772938/
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Passage of the HIV capsid cracks the nuclear pore

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sciencedirect.com/science/article/pii/S0092867424014211
Nov 2024
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Molecular basis of neurodegeneration in a mouse model of Polr3-related disease

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  DOI: 10.7554/eLife.95314
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11537486/
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Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways

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ncbi.nlm.nih.gov/pmc/articles/PMC11472510/
Sep 2024
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Fidgetin-like 2 depletion enhances cell migration by regulating GEF-H1, RhoA, and FAK

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1. scibot 25 Sep 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10541466/
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Paneth cell TNF signaling induces gut bacterial translocation and sepsis

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1. scibot 10 Sep 2024
  
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sciencedirect.com/science/article/pii/S1931312824003147
Aug 2024
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Distribution and innervation of putative arterial chemoreceptors in the bullfrog (Rana catesbeiana)

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1. scibot 02 Aug 2024
  
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  DOI: 10.1002/cne.23640
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23640/full
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Colocalization of allatotropin and tachykinin‐related peptides with classical transmitters in physiologically distinct subtypes of olfactory local interneurons in the cockroach (Periplaneta americana)

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1. scibot 02 Aug 2024
  
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onlinelibrary.wiley.com/doi/10.1002/cne.23757/full
Jun 2024
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General anaesthetics reduce acute lymphoblastic leukaemia malignancies in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms

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1. scibot 08 Jun 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11128051/
May 2024
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Impairing hydrolase transport machinery prevents human melanoma metastasis

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1. scibot 18 May 2024
  
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  DOI: 10.1038/s42003-024-06261-y
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11096325/
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Viral mimicry and memory deficits upon microglial deletion of ATRX

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1. scibot 16 May 2024
  
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  DOI: 10.1101/2024.05.07.592875
  
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biorxiv.org/content/10.1101/2024.05.07.592875v1
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Thrombopoietin mimetic stimulates bone marrow vascular and stromal niches to mitigate acute radiation syndrome

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1. scibot 01 May 2024
  
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  DOI: 10.1186/s13287-024-03734-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11057170/
Apr 2024
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TBL38 atypical homogalacturonan-acetylesterase activity and cell wall microdomain localization in Arabidopsis seed mucilage secretory cells

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1. scibot 28 Apr 2024
  
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  DOI: 10.1016/j.isci.2024.109666
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11043868/
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Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

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1. scibot 02 Apr 2024
  
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  DOI: 10.1016/j.cub.2024.03.010
  
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sciencedirect.com/science/article/pii/S0960982224003075
Mar 2024
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RAB3 phosphorylation by pathogenic LRRK2 impairs trafficking of synaptic vesicle precursors

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1. scibot 27 Mar 2024
  
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  DOI: 10.1083/jcb.202307092
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10959120/
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Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model

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1. scibot 01 Mar 2024
  
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  DOI: 10.7554/eLife.89453
  
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elifesciences.org/articles/89453
Feb 2024
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Alternative mechanisms of Notch activation by partitioning into distinct endosomal domains

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  DOI: 10.1083/jcb.202211041
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10868400/
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DLK signaling in axotomized neurons triggers complement activation and loss of upstream synapses

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1. scibot 16 Feb 2024
  
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  DOI: 10.1016/j.celrep.2024.113801
  
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RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma

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1. scibot 08 Feb 2024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10844834/
Jan 2024
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Rebalancing TGF-β/PGE2 breaks RT-induced immunosuppressive barriers by enhancing tumor-infiltrated dendritic cell homing

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ncbi.nlm.nih.gov/pmc/articles/PMC10750293/
Nov 2023
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Truncated radial glia as a common precursor in the late corticogenesis of gyrencephalic mammals

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1. scibot 26 Nov 2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10662950/
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Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination in male mice

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1. scibot 09 Nov 2023
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10625541/
Oct 2023
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Cytoplasmic division cycles without the nucleus and mitotic CDK/cyclin complexes

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1. scibot 13 Oct 2023
  
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sciencedirect.com/science/article/pii/S0092867423010310
Sep 2023
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Histone bivalency regulates the timing of cerebellar granule cell development

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ncbi.nlm.nih.gov/pmc/articles/PMC10499015/
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Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling

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1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.molcel.2023.08.005
  
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sciencedirect.com/science/article/pii/S109727652300641X
Aug 2023
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S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus

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1. scibot 10 Aug 2023
  
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sciencedirect.com/science/article/pii/S1534580723003581
Jun 2023
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The Rho1 GTPase controls anillo-septin assembly to facilitate contractile ring closure during cytokinesis

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1. scibot 29 Jun 2023
  
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RNA Helicase DDX3 Regulates RAD51 Localization and DNA Damage Repair in Ewing Sarcoma

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1. scibot 16 Jun 2023
  
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  DOI: 10.1101/2023.06.10.544474
  
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biorxiv.org/content/10.1101/2023.06.10.544474v1
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The orexinergic neurons receive synaptic input from C1 cells in rats

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  DOI: 10.1002/cne.23643
  
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ncbi.nlm.nih.gov/pmc/articles/PMC4167913/
May 2023
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True-to-scale DNA-density maps correlate with major accessibility differences between active and inactive chromatin

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1. scibot 27 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112567
  
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sciencedirect.com/science/article/pii/S2211124723005788
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Regulatory imbalance between LRRK2 kinase, PPM1H phosphatase, and ARF6 GTPase disrupts the axonal transport of autophagosomes

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1. scibot 03 May 2023
  
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  DOI: 10.1016/j.celrep.2023.112448
  
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sciencedirect.com/science/article/pii/S221112472300459X
Apr 2023
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Salmonella invasion of a cell is self-limiting due to effector-driven activation of N-WASP

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1. scibot 27 Apr 2023
  
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  DOI: 10.1016/j.isci.2023.106643
  
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sciencedirect.com/science/article/pii/S2589004223007204
Mar 2023
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The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool

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1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112242
  
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sciencedirect.com/science/article/pii/S221112472300253X
Jan 2023
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A Synthetic Polymicrobial Community Biofilm Model Demonstrates Spatial Partitioning, Tolerance to Antimicrobial Treatment, Reduced Metabolism, and Small Colony Variants Typical of Chronic Wound Biofilms

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1. scibot 19 Jan 2023
  
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  DOI: 10.3390/pathogens12010118
  
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mdpi.com/2076-0817/12/1/118
Dec 2022
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Nail-associated mesenchymal cells contribute to and are essential for dorsal digit tip regeneration

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1. scibot 24 Dec 2022
  
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F1000Research Article: General anaesthetics reduce acute lymphoblastic leukaemia cell migration and homing in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms.

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The ultrastructural organization of endoplasmic reticulum-plasma membrane contacts is conserved in epithelial cells

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The ultrastructural organization of endoplasmic reticulum-plasma membrane contacts is conserved in epithelial cells

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Condensation of the fusion focus by the intrinsically disordered region of the formin Fus1 is essential for cell-cell fusion

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Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification

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Ribbon boosts ribosomal protein gene expression to coordinate organ form and function

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Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

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Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength

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Laminin β2 Chain Regulates Cell Cycle Dynamics in the Developing Retina

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Salivary ZG16B expression loss follows exocrine gland dysfunction related to oral Chronic Graft-Versus-Host Disease

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Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion

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Regulation of Endoplasmic Reticulum–Mitochondria Tethering and Ca2+ Fluxes by TDP-43 via GSK3β

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Apical contacts stemming from incomplete delamination guide progenitor cell allocation through a dragging mechanism

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Twisting of the zebrafish heart tube during cardiac looping is a tbx5-dependent and tissue-intrinsic process

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Netrin G1 promotes pancreatic tumorigenesis through cancer associated fibroblast driven nutritional support and immunosuppression

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Proteolytically released Lasso/teneurin-2 induces axonal attraction by interacting with latrophilin-1 on axonal growth cones

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Tubulin detyrosination promotes human trophoblast syncytium formation

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Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72

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NYX‐2925 induces metabotropic NMDAR signaling that enhances synaptic NMDAR and AMPAR

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Disruption of NMDA receptor function prevents normal experience-dependent homeostatic synaptic plasticity in mouse primary visual cortex

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Rgma-induced Neo1 proteolysis promotes neural tube morphogenesis

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Simple and efficient delivery of cell-impermeable organic fluorescent probes into live cells for live-cell superresolution imaging

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Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival

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  DOI: 10.1074/jbc.RA118.007152
  
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Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation

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Synthetic Physical Interactions with the Yeast Centrosome

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Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons

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Neurofilaments form flexible bundles during neuritogenesis in culture and in mature axons in situ

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Dynamic Podosome-Like Structures in Nascent Phagosomes Are Coordinated by Phosphoinositides

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Multimerization and Retention of the Scavenger Receptor SR-B1 in the Plasma Membrane

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STIM1 Is Required for Remodeling of the Endoplasmic Reticulum and Microtubule Cytoskeleton in Steering Growth Cones

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Rem2 stabilizes intrinsic excitability and spontaneous firing in visual circuits

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The MAP1B Binding Domain of Nav1.6 Is Required for Stable Expression at the Axon Initial Segment

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Pyk2 Signaling through Graf1 and RhoA GTPase Is Required for Amyloid-β Oligomer-Triggered Synapse Loss

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Development of hair cell phenotype and calyx nerve terminals in the neonatal mouse utricle

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Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3‐dependent mechanism in male mice

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Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

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Callose-Regulated Symplastic Communication Coordinates Symbiotic Root Nodule Development

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Untitled document

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Asymmetric nuclear division in neural stem cells generates sibling nuclei that differ in size, envelope composition, and chromatin organization

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Wnt- and glutamate-receptors orchestrate stem cell dynamics and asymmetric cell division

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PHAROH lncRNA regulates Myc translation in hepatocellular carcinoma via sequestering TIAR

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Robo recruitment of the Wave regulatory complex plays an essential and conserved role in midline repulsion

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Multimerization of Zika Virus-NS5 Causes Ciliopathy and Forces Premature Neurogenesis

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Intravital Imaging Reveals Motility of Adult Hematopoietic Stem Cells in the Bone Marrow Niche

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Condensed Chromatin Behaves like a Solid on the Mesoscale In Vitro and in Living Cells

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A gradient of Wnt activity positions the neurosensory domains of the inner ear

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Mauve/LYST limits fusion of lysosome-related organelles and promotes centrosomal recruitment of microtubule nucleating proteins

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A Booster Dose Enhances Immunogenicity of the COVID-19 Vaccine Candidate ChAdOx1 nCoV-19 in Aged Mice

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Islet vascularization is regulated by primary endothelial cilia via VEGF-A-dependent signaling

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The human origin recognition complex is essential for pre-RC assembly, mitosis, and maintenance of nuclear structure

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Cone-shaped HIV-1 capsids are transported through intact nuclear pores

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Plasma cell dynamics in the bone marrow niche

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Periaxonal and nodal plasticities modulate action potential conduction in the adult mouse brain

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Lysosome Fusion Maintains Phagosome Integrity during Fungal Infection

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The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress

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Dynamin-2 Regulates Postsynaptic Cytoskeleton Organization and Neuromuscular Junction Development

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LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

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Platelets Fuel the Inflammasome Activation of Innate Immune Cells

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Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

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Single-Cell Profiling Shows Murine Forebrain Neural Stem Cells Reacquire a Developmental State when Activated for Adult Neurogenesis

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Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits

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The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

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Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

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The Protein Arginine Methyltransferase PRMT8 and Substrate G3BP1 Control Rac1-PAK1 Signaling and Actin Cytoskeleton for Dendritic Spine Maturation

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The endothelial barrier is not rate-limiting to insulin action in the myocardium of male mice

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Characterization of Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role in Herpes Simplex Keratitis

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Specific depletion of the motor protein KIF5B leads to deficits in dendritic transport, synaptic plasticity and memory

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Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor

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TMC2 Modifies Permeation Properties of the Mechanoelectrical Transducer Channel in Early Postnatal Mouse Cochlear Outer Hair Cells

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Extracellular matrix stiffness cues junctional remodeling for 3D tissue elongation

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On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

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The antimicrobial peptide defensin cooperates with tumour necrosis factor to drive tumour cell death in Drosophila

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Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

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Acquisition of a Unique Mesenchymal Precursor-like Blastema State Underlies Successful Adult Mammalian Digit Tip Regeneration

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CCL2 mobilizes ALIX to facilitate Gag-p6 mediated HIV-1 virion release

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Capping Protein Insulates Arp2/3-Assembled Actin Patches from Formins

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HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex

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Presynaptic loss of dynamin‐related protein 1 impairs synaptic vesicle release and recycling at the mouse calyx of Held

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The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity

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Basal Protrusions Mediate Spatiotemporal Patterns of Spinal Neuron Differentiation

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Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea

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Untitled document

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Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

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Untitled document

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Untitled document

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Laminin β2 Chain Regulates Retinal Progenitor Cell Mitotic Spindle Orientation via Dystroglycan

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The X-linked Mental Retardation Protein OPHN1 Interacts with Homer1b/c to Control Spine Endocytic Zone Positioning and Expression of Synaptic Potentiation

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Colocalization of allatotropin and tachykinin‐related peptides with classical transmitters in physiologically distinct subtypes of olfactory local interneurons in the cockroach (Periplaneta americana)

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The orexinergic neurons receive synaptic input from C1 cells in rats

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Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis

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The Highwire Ubiquitin Ligase Promotes Axonal Degeneration by Tuning Levels of Nmnat Protein

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A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression

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Lymphocyte-Derived Exosomal MicroRNAs Promote Pancreatic β Cell Death and May Contribute to Type 1 Diabetes Development

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Presynaptic GCaMP expression decreases vesicle release probability at the Calyx of Held

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Impeding DNA Break Repair Enables Oocyte Quality Control

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Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells

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POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication

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Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease

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Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

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mTOR Regulates Phase Separation of PGL Granules to Modulate Their Autophagic Degradation

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Polarized Dock Activity Drives Shh-Mediated Axon Guidance

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α-Toxin Induces Platelet Aggregation and Liver Injury during Staphylococcus aureus Sepsis

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Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

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Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

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Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis

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Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

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iNKT Cells Orchestrate a Switch from Inflammation to Resolution of Sterile Liver Injury

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The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis

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Thyroid Hormone Receptor β Suppression of RUNX2 is Mediated by Brahma Related Gene 1 Dependent Chromatin Remodeling

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CRISPR-based herd immunity can limit phage epidemics in bacterial populations

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FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

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Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe

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Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain

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Fat Body Cells Are Motile and Actively Migrate to Wounds to Drive Repair and Prevent Infection

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Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function

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Neurotransmitter Diversity In Pre‐Synaptic Terminals Located in the Parvicellular Neuroendocrine Paraventricular Nucleus of the Rat and Mouse Hypothalamus

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Anatomical characterization of PDF‐Tri neurons and peptidergic neurons associated with eclosion behavior in Drosophila

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A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

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A Distinct Class of Genome Rearrangements Driven by Heterologous Recombination

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Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

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Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome

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Genetic disruption of fractalkine signaling leads to enhanced loss of cochlear afferents following ototoxic or acoustic injury

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Transcriptional Architecture of Synaptic Communication Delineates GABAergic Neuron Identity

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The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation

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A novel Drosophila injury model reveals severed axons are cleared through a Draper/MMP-1 signaling cascade

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RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

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Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others

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Mid‐life environmental enrichment increases synaptic density in CA1 in a mouse model of Aβ‐associated pathology and positively influences synaptic and cognitive health in healthy ageing

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Migrating Interneurons Secrete Fractalkine to Promote Oligodendrocyte Formation in the Developing Mammalian Brain

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TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

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Cellular localization of relaxin‐like gonad‐stimulating peptide expression in Asterias rubens: New insights into neurohormonal control of spawning in starfish

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Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency

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Mutant Huntingtin Disrupts the Nuclear Pore Complex

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Position- and Hippo signaling-dependent plasticity during lineage segregation in the early mouse embryo

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MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos

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CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development

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Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1

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Converging, Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses

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