919 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fast volumetric fluorescence lifetime imaging of multicellular systems using single-objective light-sheet microscopy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12715196/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimal CXCR5 expression during Tfh maturation involves the Bhlhe40-Pou2af1 axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12744931/
  4. Apr 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Models of the human heart for biomedical research: Opportunities and challenges
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    pmc.ncbi.nlm.nih.gov/articles/PMC13062934/
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dentate gyrus development requires a cortical hem-derived astrocytic scaffold
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    pmc.ncbi.nlm.nih.gov/articles/PMC7806271/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Senescence-inhibitory Δ133p53α counteracts accelerated ageing and mortality
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    pmc.ncbi.nlm.nih.gov/articles/PMC12776339/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vasoactive Intestinal Peptide Deficiency Is Associated With Altered Gut Microbiota Communities in Male and Female C57BL/6 Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC6900961/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Genome Architecture of the Collaborative Cross Mouse Genetic Reference Population
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    pmc.ncbi.nlm.nih.gov/articles/PMC3276630/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypothalamic tuberomammillary nucleus neurons: electrophysiological diversity and essential role in arousal stability
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    pmc.ncbi.nlm.nih.gov/articles/PMC5618271/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Unraveling the genetics of arsenic toxicity with cellular morphology QTL
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    pmc.ncbi.nlm.nih.gov/articles/PMC11075906/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sestrin-2, a repressor of PDGFRβ signalling, promotes cigarette-smoke-induced pulmonary emphysema in mice and is upregulated in individuals with COPD
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    pmc.ncbi.nlm.nih.gov/articles/PMC3820261/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute and long-term effects of antibiotics commonly used in laboratory animal medicine on the fecal microbiota
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    pmc.ncbi.nlm.nih.gov/articles/PMC7489021/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dopaminergic Modulation of Striatal Inhibitory Transmission and Long-Term Plasticity
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    pmc.ncbi.nlm.nih.gov/articles/PMC4534630/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KV7 Channels Regulate Firing during Synaptic Integration in GABAergic Striatal Neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC4465714/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanism of STMN2 cryptic splice/polyadenylation and its correction for TDP-43 proteinopathies
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    pmc.ncbi.nlm.nih.gov/articles/PMC10148063/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC10903950/
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC4809561/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protein coding variation in the J:ARC and J:DO outbred laboratory mouse stocks provides a molecular basis for distinct research applications
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    pmc.ncbi.nlm.nih.gov/articles/PMC10085793/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effect of Shipping on the Microbiome of Donor Mice Used to Reconstitute Germ-Free Recipients
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    pmc.ncbi.nlm.nih.gov/articles/PMC11423901/
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preclinical use of a clinically-relevant scAAV9/SUMF1 vector for the treatment of multiple sulfatase deficiency
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    pmc.ncbi.nlm.nih.gov/articles/PMC11772666/
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interleukin-17D and Nrf2 mediate initial innate immune cell recruitment and restrict MCMV infection
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    pmc.ncbi.nlm.nih.gov/articles/PMC6135835/
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The dynamics of TGF-β in dental pulp, odontoblasts and dentin
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    pmc.ncbi.nlm.nih.gov/articles/PMC5849713/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibitory circuit gating of auditory critical-period plasticity
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    pmc.ncbi.nlm.nih.gov/articles/PMC5978727/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rescue of germline transmission from chimeras by IVF after sperm analysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC4276497/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Informatics resources for the Collaborative Cross and related mouse populations
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    pmc.ncbi.nlm.nih.gov/articles/PMC4633285/
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cortical hem lacks stem cell potential despite expressing SOX9 and HOPX
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    pmc.ncbi.nlm.nih.gov/articles/PMC9826121/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Strategies for Labeling AT2 Cells in Murine Lung via Abca3 and Etv5-Driven Reporters
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    pmc.ncbi.nlm.nih.gov/articles/PMC13025979/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A hypoxia-sensitive medullary nucleus modulates cerebral blood flow via a disynaptic pathway to cortex
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    pmc.ncbi.nlm.nih.gov/articles/PMC12934959/
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    s12974-026-03738-x_reference-html.html
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    pmc.ncbi.nlm.nih.gov/articles/PMC13019958/
  31. Mar 2026
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Light tunes long-term threat avoidance behavior in male mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13013830/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct roles of cortical layer 5 subtypes in associative learning
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    pmc.ncbi.nlm.nih.gov/articles/PMC13004866/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The origin of hepatocellular carcinoma depends on metabolic zonation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12999168/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PD-1 genetic fate mapping uncovers immune cell diversity mediating the efficacy of combined PD-1 blockade and chemotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12969739/
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Calcium Pump ATP2B1/PMCA1 Regulates CNS Vascular Development by Facilitating Norrin- and WNT7A/B-induced Frizzled4 signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12330718/
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-Cell Profiling of the Developing Organ of Corti Identifies Etv4/5/1 as Key Regulators of Pillar Cell Identity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12892159/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    N-Acetylcysteine Ameliorates Loss of the Electroretinogram b-wave in a Bardet-Biedl Syndrome Type 10 Mouse Model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12459551/
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Promoting the nuclear retention of HMGB1 attenuates astrocyte senescence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12888629/
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CBX7 functions as a methylation-dependent inducer of gene transcription and regulator of cytosolic signaling in lymphoid cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12904207/
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    International Mouse Phenotyping Consortium Portal: facilitating investigation of gene function and providing insights into human disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12807668/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protection of multiple aspects of Alzheimer’s disease pathology using dietary supplementation with taurine
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    pmc.ncbi.nlm.nih.gov/articles/PMC12827476/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900649/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Estradiol regulates osteoclast sialylation via ST3Gal1 in postmenopausal osteoporosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12901315/
  45. Feb 2026
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The cAMP-phosphodiesterase PDE4B2 controls peroxisome proliferator-activated receptor γ (PPARγ) expression and the initiation of adipogenesis in 3T3-L1 cells. | American Journal of Physiology-Endocrinology and Metabolism | American Physiological Society
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    1. scibot 11 Feb 2026
      PDE4B knockout (KO) mice (46) were generated by Drs. S.-L. Catherine Jin and Marco Conti (Stanford University, CA), and kindly distributed via the Mutant Mouse Resource and Research Centers (MMRRC)

      DOI: 10.1152/ajpendo.00215.2025

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC12870952/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Longitudinal single-cell profiles of lung regeneration after viral infection reveal persistent injury-associated cell states
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    pmc.ncbi.nlm.nih.gov/articles/PMC11805657/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PPM1M, an LRRK2-counteracting, phosphoRab12-preferring phosphatase with a potential link to Parkinson’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12462683/
  49. Jan 2026
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The mechanosensitive channel TRPV4 inhibits pulmonary inflammation by limiting NF-KB signaling in alveolar macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12781032/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An open-source system for recording the auditory brainstem response (ABR) and an example application in mice with hearing loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC12724443/
  52. Dec 2025
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dominant effects of the immediate environment on the gut microbiome of mice used in biomedical research
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    1. scibot 31 Dec 2025
      Colonies of outbred CD-1 mice harboring distinct supplier-origin (SO) GMs were established in 2017 (23) and have been maintained continuously since then at the Mutant Mouse Resource and Research Center at the University of Missouri (MU MMRRC)

      DOI: 10.1128/msystems.01112-25

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @AleksanderDrozdz

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    pmc.ncbi.nlm.nih.gov/articles/PMC12710307/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biological and technical variability in mouse microbiota analysis and implications for sample size determination
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    pmc.ncbi.nlm.nih.gov/articles/PMC12738283/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fetal programming by the parental microbiome of offspring behavior, and DNA methylation and gene expression within the hippocampus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12699845/
  56. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Erythroid-specific, inducible CDAN1∆/∆ mouse model phenocopies congenital dyserythropoietic anemia type-la
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    sciencedirect.com:5037/science/article/pii/S0006497125027612
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Canagliflozin Reprograms the Aging Hippocampus in Genetically Diverse UM‐HET3 Mice and Attenuates Alzheimer's‐Like Pathology
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    pmc.ncbi.nlm.nih.gov/articles/PMC12686575/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA modifications, alternative splicing and circular RNA landscape in the mouse brain: inosine and beyond
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    pmc.ncbi.nlm.nih.gov/articles/PMC12775412/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protection of multiple aspects of Alzheimer’s disease pathology using dietary supplementation with taurine
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    pmc.ncbi.nlm.nih.gov/articles/PMC12632585/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Brain region-specific dopamine receptor changes and astrocyte activation influence tau pathology through CDK5 in Alzheimer's disease models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12664925/
  61. Oct 2025
  62. journals.plos.org journals.plos.org
    Klotho null mutation leads to retinal degeneration characterized by functional impairment, gliosis, and deposition of amyloid-beta and hyperphosphorylated tau proteins
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    journals.plos.org/plosone/article
  63. journals.sagepub.com journals.sagepub.com
    Amyloid beta peptides inhibit glucose transport at the blood-brain barrier by disrupting the insulin-AKT pathway
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    journals.sagepub.com/doi/10.1177/0271678X251332493
  64. www.biorxiv.org www.biorxiv.org
    Direct comparison of constitutive Rax-Cre transgenic drivers that activate in the mouse embryonic eye field
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    biorxiv.org/content/10.1101/2025.10.11.681822v1
  65. www.biorxiv.org www.biorxiv.org
    International Mouse Phenotyping Consortium: Investigating gene function and providing insights into human disease
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    biorxiv.org/content/10.1101/2025.10.09.681205v1
  66. www.biorxiv.org www.biorxiv.org
    Submedius Thalamus Modulates Orbitofrontal Cortex Representations During Maternal Behavior in Mice
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    biorxiv.org/content/10.1101/2025.09.18.677207v1
  67. www.biorxiv.org www.biorxiv.org
    Neuronal HDAC9: A key regulator of cognitive and synaptic aging, rescuing Alzheimer’s disease-related phenotypes
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    biorxiv.org/content/10.1101/2025.09.13.675847v1
  68. www.biorxiv.org www.biorxiv.org
    AGO2 slicing of a domesticated retrotransposon is necessary for normal vasculature development
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    biorxiv.org/content/10.1101/2025.04.02.646793v1
  69. www.biorxiv.org www.biorxiv.org
    Platelet endocytosis and α-granule cargo packaging are essential for normal skin wound healing
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    biorxiv.org/content/10.1101/2025.02.01.636051v1
  70. www.pnas.org www.pnas.org
    A midbrain-to-ventral-striatum dopaminergic pathway orchestrates odor-guided insect predation in mice
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    pnas.org/doi/10.1073/pnas.2514847122
  71. www.sciencedirect.com www.sciencedirect.com
    Impaired persistence of cortical sensory adaptation following repetitive tactile stimulation in the hindlimb somatosensory cortex of Rett syndrome mice
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    sciencedirect.com/science/article/pii/S0306452225006682
  72. www.cell.com www.cell.com
    Parental origin of transgene modulates amyloid-β plaque burden in the 5xFAD mouse model of Alzheimer’s disease
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    cell.com/neuron/fulltext/S0896-6273(24)00925-5
  73. www.sciencedirect.com www.sciencedirect.com
    Open-source antibodies as a path to enhanced research reproducibility and transparency
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    sciencedirect.com/science/article/pii/S1871678425000421
  74. www.sciencedirect.com www.sciencedirect.com
    Novel Non-Invasive PET Imaging of Reactive Oxygen Species Using [18 F]ROStrace in Three Proteinopathy-Associated Neurodegenerative Mouse Models
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    sciencedirect.com/science/article/pii/S1076633225007317
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual roles of in situ generated HSP70 in antigen delivery and immunoregulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12528137/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A High Through-Put Reverse Genetic Screen Identifies Two Genes Involved in Remote Memory in Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC2373872/
  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Contemporary approaches for modifying the mouse genome
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    pmc.ncbi.nlm.nih.gov/articles/PMC2519963/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Characterization of transcriptomic changes in the neurovascular unit of Alzheimiers transgenic mouse models using digital spatial profiling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12148062/
  79. www.sciencedirect.com www.sciencedirect.com
    Transcriptional profiling of mouse and human ES cells identifies SLAIN1, a novel stem cell gene
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    1. scibot 16 Oct 2025
      XG385, XG752, and XH855) that contained a βgeo fusion gene inserted into intron B of Slain1 (as illustrated Fig. 8A) were obtained from the Mutant Mouse Regional Resource Center (http://www.mmrrc.org/)

      DOI: 10.1016/j.ydbio.2006.01.023

      Resource: Mutant Mouse Regional Resource Center (RRID:SCR_002953)

      Curator: @AleksanderDrozdz

      SciCrunch record: RRID:SCR_002953

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    sciencedirect.com/science/article/pii/S0012160606000510
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic Dissection of Neural Circuits
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    pmc.ncbi.nlm.nih.gov/articles/PMC2628815/
  81. www.sciencedirect.com www.sciencedirect.com
    Distribution of the orexin-1 receptor (OX1R) in the mouse forebrain and rostral brainstem: A characterisation of OX1R-eGFP mice
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    sciencedirect.com/science/article/pii/S0891061815000162
  82. www.cell.com www.cell.com
    C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection
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    cell.com/immunity/fulltext/S1074-7613(13)00298-7
  83. www.cell.com www.cell.com
    A Mouse for All Reasons
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    cell.com/cell/fulltext/S0092-8674(06)01612-6
  84. www.sciencedirect.com www.sciencedirect.com
    Generation of an ABCG2GFPn-puro transgenic line – A tool to study ABCG2 expression in mice
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    sciencedirect.com/science/article/abs/pii/S0006291X09008079
  85. www.sciencedirect.com www.sciencedirect.com
    Effect of arylformamidase (kynurenine formamidase) gene inactivation in mice on enzymatic activity, kynurenine pathway metabolites and phenotype
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    sciencedirect.com/science/article/abs/pii/S0304416505000863
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A sensitive biosensor of endogenous Gαi activity enables the accurate characterization of endogenous GPCR agonist responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12077488/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Striatal pathways oppositely shift cortical activity along the decision axis
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  88. Sep 2025
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    Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer’s disease mouse model
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  92. Aug 2025
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    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact
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    Correlates of head-fixed orienting movements in mouse superior colliculus and substantia nigra pars reticulata
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  96. Jul 2025
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    Single-cell transcriptomics of ventral forebrain progenitors identifies Evf2 enhancer lncRNA-enhancer gene guidance through direct RNA binding and RNP recruitment domains
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  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Amelogenin Null Mice Develop Osteoarthritis, While Its Application Mitigates Disease Phenotypes in a Rat Model
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    Sex-dependent influence of LMAN1 on allergen-induced airway hyperresponsiveness
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    Synergistic Inhibition of Prostate Cancer Progression in Mice With a Combination of Curcumin and Ursolic Acid in the Diet
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  101. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Paradoxical mTORC1-Dependent microRNA-mediated Translation Repression in the Nucleus Accumbens of Male Mice Consuming Alcohol Attenuates Glycolysis
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  102. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Timing of standard chow exposure determines the variability of mouse phenotypic outcomes and gut microbiota profile
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    The distinct roles of NEIL1 and XPA in limiting aflatoxin B1-induced mutagenesis in mice
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  104. Jun 2025
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  106. Apr 2025
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    Spinal lumbar Urocortin 3-expressing neurons are associated with both scratching and Compound 48/80-induced sensations
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  109. Mar 2025
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  111. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation and Characterization of a Knockout Mouse of an Enhancer of EBF3
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  112. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  113. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Meibomian gland lipid alterations and ocular surface sequela in Awat2 knockout murine model of meibomian gland dysfunction and evaporative dry eye disease
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  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cellular‐Resolution and Bulk‐Fluorescence Recordings of Calcium Activity Yield Reciprocal Readouts of In Vivo Drug Efficacy
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  115. Feb 2025
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  118. Jan 2025
  119. journals.lww.com journals.lww.com
    How the University of Washington Implemented a Change in... : Kidney360
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  120. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Abnormal c-Fos expression in TetTag mice containing fos-EGFP
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  121. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation and Characterization of a TRIM21 Overexpressing Mouse Line
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  122. Dec 2024
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    CCR8 Signaling Regulates IL-25- and IL-33-Responsive Skin Group 2 Innate Lymphoid Cell Migration and Function
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    ADAM10 Expression by Ameloblasts Is Essential for Proper Enamel Formation
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  126. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Leaky gate model: intensity-dependent coding of pain and itch in the spinal cord
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  127. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Analysis of CNS autoimmunity in genetically diverse mice reveals unique phenotypes and mechanisms
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  128. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing striatal acetylcholine facilitates dopamine release and striatal output in parkinsonian mice
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  129. Nov 2024
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    Manganese Exposure Enhances the Release of Misfolded α-Synuclein via Exosomes by Impairing Endosomal Trafficking and Protein Degradation Mechanisms
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    Two distinct populations of H chain edited B cells show differential surrogate L chain dependence
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    Dissecting inhibitory brain circuits with genetically-targeted technologies
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  133. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Molecular Chaperone Hsp90α Is Required for Meiotic Progression of Spermatocytes beyond Pachytene in the Mouse
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  134. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cpd-1 Null Mice Display a Subtle Neurological Phenotype
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  135. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MiR-155 Induction by F. novicida but Not the Virulent F. tularensis Results in SHIP Down-Regulation and Enhanced Pro-Inflammatory Cytokine Response
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  136. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Flavonoid Luteolin Worsens Chemical-Induced Colitis in NF-κBEGFP Transgenic Mice through Blockade of NF-κB-Dependent Protective Molecules
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  137. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bergmann Glia and the Recognition Molecule CHL1 Organize GABAergic Axons and Direct Innervation of Purkinje Cell Dendrites
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  138. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development
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  139. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neural Crest-Specific Loss of Prkar1a Causes Perinatal Lethality Resulting from Defects in Intramembranous Ossification
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    Glucose-dependent blood flow dynamics in murine pancreatic islets in vivo
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  141. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gene Trap Disruption of the Mouse Heparan Sulfate 6-O-Endosulfatase Gene, Sulf2
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    Nedd4 Controls Animal Growth by Regulating IGF-1 Signaling
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  143. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phenotypic annotation of the mouse X chromosome
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  144. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved
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  145. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Absence seizures in C3H/HeJ and knockout mice caused by mutation of the AMPA receptor subunit Gria4
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  146. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Loss of the lupus autoantigen Ro52/Trim21 induces tissue inflammation and systemic autoimmunity by disregulating the IL-23–Th17 pathway
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  147. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Silencing Mediator of Retinoid and Thyroid Hormone Receptors (SMRT) Regulates Adipose Tissue Accumulation and Adipocyte Insulin Sensitivity in Vivo
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  148. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A regulatory toolbox of MiniPromoters to drive selective expression in the brain
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  149. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone
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  150. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ubiquitin carboxyl-terminal hydrolase L1 is required for maintaining the structure and function of the neuromuscular junction
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  151. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gene-trapped mouse embryonic stem cell-derived cardiac myocytes and human genetics implicate AKAP10 in heart rhythm regulation
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  152. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pdk1 activity controls proliferation, survival, and growth of developing pancreatic cells
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  153. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Vesicular Glutamate Transport Promotes Dopamine Storage and Glutamate Corelease In Vivo
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  154. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    New monoclonal anti-mouse DC-SIGN antibodies reactive with acetone-fixed cells
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  155. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimal Germinal Center Responses Require A Multi-stage T:B Cell Adhesion Process Involving Integrins, SLAM-associated protein and CD84
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  156. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Toll-like Receptor 7 Mitigates Lethal West Nile Encephalitis via Interleukin 23-Dependent Immune Cell Infiltration and Homing
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  157. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Generation of follicular helper T cells is mediated by IL-21 but independent of TH1, TH2 or TH17 lineages
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  158. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sigma-1 receptor knockout mice display a depressive-like phenotype
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  159. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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  160. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Assessment of PD-1H Coinhibitory Receptor-Induced T-Cell Tolerance to Allogeneic Antigens
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  161. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CXCL17 is a major chemotactic factor for lung macrophages
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  162. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Development of a Unilaterally-lesioned 6-OHDA Mouse Model of Parkinson's Disease
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  163. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conditional gene manipulation: Cre-ating a new biological era
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  164. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Safety, efficacy and efficiency of laser-assisted IVF in subfertile mutant mouse strains
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  165. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Rapid, Activity-Independent Turnover of Vesicular Transmitter Content at a Mixed Glycine/GABA Synapse
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  166. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Depletion of GGA1 and GGA3 Mediates Postinjury Elevation of BACE1
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  167. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elimination of Redundant Synaptic Inputs in the Absence of Synaptic Strengthening
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  168. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Synaptic Circuit Organization of Motor Corticothalamic Neurons
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  169. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Transsynaptic Tracing with Vesicular Stomatitis Virus Reveals Novel Retinal Circuitry
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  170. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative Evaluation of DNA Extraction Methods from Feces of Multiple Host Species for Downstream Next-Generation Sequencing
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  171. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effects of Vendor and Genetic Background on the Composition of the Fecal Microbiota of Inbred Mice
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  172. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The imprinted polycomb group gene Sfmbt2 is required for trophoblast maintenance and placenta development
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  173. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential Role of PKA Catalytic Subunits in Mediating Phenotypes Caused by Knockout of the Carney Complex Gene Prkar1a
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  174. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differentially Regulated Protein Kinase A (PKA) Activity in Adipose Tissue and Liver Is Associated With Resistance to Diet-Induced Obesity and Glucose Intolerance in Mice That Lack PKA Regulatory Subunit Type IIα
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  175. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A VISTA on PD-1H
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  176. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria
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  177. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice
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  178. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adoptively transferred TRAIL+ T cells suppress GVHD and augment antitumor activity
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  179. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Disruption of intraflagellar protein transport in photoreceptor cilia causes Leber congenital amaurosis in humans and mice
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  180. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MyD88 is critically involved in immune tolerance breakdown at environmental interfaces of Foxp3-deficient mice
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  181. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    β-Adrenergic Regulation of the L-type Ca2+ Channel does not Require Phosphorylation of α1C Ser1700
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    pmc.ncbi.nlm.nih.gov/articles/PMC3864014/
  182. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Combined Vitamin C and Vitamin E Deficiency Worsens Early Atherosclerosis in ApoE-Deficient Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC2924448/
  183. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Trypsin causes platelet activation independently of known protease-activated receptors
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    pmc.ncbi.nlm.nih.gov/articles/PMC4077195/
  184. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dietary Energy Balance Modulates Prostate Cancer Progression in Hi-Myc Mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC4171652/
  185. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PanIN-specific regulation of Wnt signaling by HIF2α during early pancreatic tumorigenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC3736839/
  186. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exoelectrogenic capacity of host microbiota predicts lymphocyte recruitment to the gut
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    pmc.ncbi.nlm.nih.gov/articles/PMC4491528/
  187. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor Necrosis Factor Alpha and Inflammation Disrupt the Polarity Complex in Intestinal Epithelial Cells by a Posttranslational Mechanism
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    pmc.ncbi.nlm.nih.gov/articles/PMC3028658/
  188. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Galectin-1 Binds to Influenza Virus and Ameliorates Influenza Virus Pathogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC3196456/
  189. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal
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    pmc.ncbi.nlm.nih.gov/articles/PMC3028852/
  190. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Role of Ficolin-A and Lectin Complement Pathway in the Innate Defense against Pathogenic Aspergillus Species
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    pmc.ncbi.nlm.nih.gov/articles/PMC3647983/
  191. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining Functional Gene-Circuit Interfaces in the Mouse Nervous System
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    pmc.ncbi.nlm.nih.gov/articles/PMC3947308/
  192. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Induction of autoimmune diabetes in non-obese diabetic mice requires interleukin-21-dependent activation of autoreactive CD8+ T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC3722919/
  193. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Exploring host–microbiota interactions in animal models and humans
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    pmc.ncbi.nlm.nih.gov/articles/PMC3639412/
  194. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development
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    pmc.ncbi.nlm.nih.gov/articles/PMC3834788/