284 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
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    1. scibot 21 Dec 2024
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      DOI: 10.1101/2024.11.11.24317113

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    pmc.ncbi.nlm.nih.gov/articles/PMC11601780/
  3. elifesciences.org elifesciences.org
    Full-length direct RNA sequencing uncovers stress granule-dependent RNA decay upon cellular stress
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    1. scibot 20 Dec 2024
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      DOI: 10.7554/eLife.96284

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  4. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027937-main-html.html
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    1. scibot 19 Dec 2024
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      DOI: 10.1016/j.isci.2024.111566

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  5. www.sciencedirect.com www.sciencedirect.com
    Tubulin sequence divergence is associated with the use of distinct microtubule regulators
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    1. scibot 18 Dec 2024
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      DOI: 10.1016/j.cub.2024.11.022

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  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Satb1 regulates Contactin 5 to pattern dendrites of a mammalian retinal ganglion cell
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    1. scibot 17 Dec 2024
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      DOI: 10.1016/j.neuron.2017.07.019

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    pmc.ncbi.nlm.nih.gov/articles/PMC5575751/
  7. Dec 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The telomere-to-telomere (T2T) genome provides insights into the evolution of specialized centromere sequences in sandalwood
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    1. scibot 13 Dec 2024
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      DOI: 10.1093/gigascience/giae096

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    pmc.ncbi.nlm.nih.gov/articles/PMC11633456/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    1. scibot 13 Dec 2024
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      DOI: 10.1038/s44321-024-00161-8

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  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    1. scibot 11 Dec 2024
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      DOI: 10.1158/2159-8290.CD-23-0866

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
  11. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
    1
    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.009

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    sciencedirect.com/science/article/pii/S1097276524009146
  12. www.mdpi.com www.mdpi.com
    Biliverdinuria Caused by Exonic BLVRA Deletions in Two Dogs with Green Urine
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    1. scibot 03 Dec 2024
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      DOI: 10.3390/genes15121561

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    mdpi.com/2073-4425/15/12/1561
  13. Nov 2024
  14. 52.53.155.43 52.53.155.43
    ccr-24-1240-html.html
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    1. scibot 14 Nov 2024
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      DOI: 10.1158/1078-0432.ccr-24-1240

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  15. Oct 2024
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    1. scibot 04 Oct 2024
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      DOI: 10.1158/1078-0432.CCR-23-3780

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443220/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1158/2326-6066.CIR-23-0622

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  18. www.nature.com www.nature.com
    Use of synthetic circular RNA spike-ins (SynCRS) for normalization of circular RNA sequencing data
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    1. scibot 03 Oct 2024
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      DOI: 10.1038/s41596-024-01053-4

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    nature.com/articles/s41596-024-01053-4
  19. Sep 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-speed whole-genome sequencing of a Whippet: Rapid chromosome-level assembly and annotation of an extremely fast dog’s genome
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    1. scibot 26 Sep 2024
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      DOI: 10.46471/gigabyte.134

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    ncbi.nlm.nih.gov/pmc/articles/PMC11418881/
  21. Aug 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114640

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    ncbi.nlm.nih.gov/pmc/articles/PMC11406439/
  23. www.sciencedirect.com www.sciencedirect.com
    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.molcel.2024.08.007

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    sciencedirect.com/science/article/pii/S1097276524006610
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    1. scibot 22 Aug 2024
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      DOI: 10.1158/0008-5472.CAN-24-1090

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    ncbi.nlm.nih.gov/pmc/articles/PMC11325147/
  25. www.sciencedirect.com www.sciencedirect.com
    Genomic dynamics of the Lower Yellow River Valley since the Early Neolithic
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.cub.2024.07.063

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    sciencedirect.com/science/article/pii/S0960982224010029
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SOX10 loss sensitizes melanoma cells to cytokine-mediated inflammatory cell death
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    1. scibot 18 Aug 2024
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      DOI: 10.1158/1541-7786.MCR-23-0290

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    ncbi.nlm.nih.gov/pmc/articles/PMC10842433/
  27. Jul 2024
  28. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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    1. scibot 25 Jul 2024
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      DOI: 10.1016/j.immuni.2024.07.001

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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
  29. www.sciencedirect.com www.sciencedirect.com
    The primitive endoderm supports lineage plasticity to enable regulative development
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    1. scibot 24 Jul 2024
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      DOI: 10.1016/j.cell.2024.05.051

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    sciencedirect.com/science/article/pii/S0092867424005956
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stochastic RNA editing of the Complexin C-terminus within single neurons regulates neurotransmitter release
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    1. scibot 08 Jul 2024
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      DOI: 10.1016/j.celrep.2023.113152

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    ncbi.nlm.nih.gov/pmc/articles/PMC10591831/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
    1
    1. scibot 06 Jul 2024
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      DOI: 10.1016/j.isci.2024.110135

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    ncbi.nlm.nih.gov/pmc/articles/PMC11223086/
  32. Jun 2024
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Impacts of in-vitro zebularine treatment on genome-wide DNA methylation and transcriptomic profiles in Salix purpurea L.
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    1. scibot 28 Jun 2024
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      DOI: 10.1111/ppl.14403

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    onlinelibrary.wiley.com/doi/10.1111/ppl.14403
  34. May 2024
  35. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
    3
    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    2. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    3. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
  36. www.sciencedirect.com www.sciencedirect.com
    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.molcel.2024.05.002

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    sciencedirect.com/science/article/pii/S1097276524003952
  37. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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      DOI: 10.1158/1541-7786.mcr-23-0295

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    52.53.155.43/d0655220046c67483bcefd25ef239fc58ad80cdd/mcr-23-0295-html.html
  38. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  39. www.sciencedirect.com www.sciencedirect.com
    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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      DOI: 10.1016/j.immuni.2024.04.026

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    sciencedirect.com/science/article/pii/S1074761324002310
  40. aacrjournals.org aacrjournals.org
    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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      DOI: 10.1158/1078-0432.CCR-23-2438

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    aacrjournals.org/clincancerres/article/30/10/2272/745168/Integrative-Molecular-Analyses-of-the-MD-Anderson
  41. www.sciencedirect.com www.sciencedirect.com
    Integrative molecular and spatial analysis reveals evolutionary dynamics and tumor-immune interplay of in situ and invasive acral melanoma
    1
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      DOI: 10.1016/j.ccell.2024.04.012

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    sciencedirect.com/science/article/pii/S1535610824001363
  42. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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      DOI: 10.1016/j.cell.2024.04.023

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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
  43. www.sciencedirect.com www.sciencedirect.com
    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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      DOI: 10.1016/j.stem.2024.04.015

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    sciencedirect.com/science/article/pii/S1934590924001425
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Swd2/Cps35 determines H3K4 tri-methylation via interactions with Set1 and Rad6
    1
    1. scibot 09 May 2024
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      DOI: 10.1186/s12915-024-01903-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11069235/
  45. Apr 2024
  46. www.sciencedirect.com www.sciencedirect.com
    No evidence for ac4C within human mRNA upon data reassessment
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      DOI: 10.1016/j.molcel.2024.03.017

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    sciencedirect.com/science/article/pii/S1097276524002272
  47. www.sciencedirect.com www.sciencedirect.com
    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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      DOI: 10.1016/j.devcel.2024.03.020

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    sciencedirect.com/science/article/pii/S1534580724001886
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
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    Sex and age affect depot expression of Ca2+ channels in rat white fat adipocytes
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    Epigenetic MLH1 silencing concurs with mismatch repair deficiency in sporadic, naturally occurring colorectal cancer in rhesus macaques
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    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    SARS-CoV-2 RNA stabilizes host mRNAs to elicit immunopathogenesis
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    Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
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  70. Nov 2023
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    SERPINB3-MYC axis induces the basal-like/squamous subtype and enhances disease progression in pancreatic cancer
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  75. Oct 2023
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    Characterization of the male-specific region containing the candidate sex-determining gene in Amur catfish (Silurus asotus) using third-generation- and pool-sequencing data
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    Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma
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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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  97. May 2023
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    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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    CHD-associated enhancers shape human cardiomyocyte lineage commitment
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  103. Mar 2023
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    Complex Patterns of Genomic Heterogeneity Identified in 42 Tumor Samples and ctDNA of a Pulmonary Atypical Carcinoid Patient
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    ViReMa: a virus recombination mapper of next-generation sequencing data characterizes diverse recombinant viral nucleic acids
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    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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  110. Feb 2023
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  112. Jan 2023
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    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
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    Identification of regenerating island-derived protein 3E in dogs
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    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    Case report: A novel case of parental mosaicism in SMC1A gene causes inherited Cornelia de Lange syndrome
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  126. Sep 2022
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    Loss of key endosymbiont genes may facilitate early host control of the chromatophore in Paulinella
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    Differential regulation of alternate promoter regions in Sox17 during endodermal and vascular endothelial development
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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  136. Jun 2022
  137. www.nature.com www.nature.com
    The first long-read nuclear genome assembly of Oryza australiensis, a wild rice from northern Australia
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    Global-run on sequencing identifies Gm11967 as an Akt-dependent long noncoding RNA involved in insulin sensitivity
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  139. May 2022
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    H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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  143. Apr 2022
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    An adult-stage transcriptional program for survival of serotonergic connectivity
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    Growth factor independence underpins a paroxysmal, aggressive Wnt5aHigh/EphA2Low phenotype in glioblastoma stem cells, conducive to experimental combinatorial therapy
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    Znhit1 controls meiotic initiation in male germ cells by coordinating with Stra8 to activate meiotic gene expression
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  148. Mar 2022
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    Metabolic incorporation of electron-rich ribonucleosides enhances APEX-seq for profiling spatially restricted nascent transcriptome
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    piRNAs initiate transcriptional silencing of spermatogenic genes during C. elegans germline development
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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  178. Aug 2021
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    Epigenomic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria
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    An essential role for the piRNA pathway in regulating the ribosomal RNA pool in C. elegans
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    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
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  190. Jul 2021
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    HOXA9 promotes MYC-mediated leukemogenesis by maintaining gene expression for multiple anti-apoptotic pathways
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    Exon Junction Complexes Suppress Spurious Splice Sites to Safeguard Transcriptome Integrity
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    Native Chromatin Proteomics Reveals a Role for Specific Nucleoporins in Heterochromatin Organization and Maintenance
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  197. elifesciences.org elifesciences.org
    Tyr1 phosphorylation promotes phosphorylation of Ser2 on the C-terminal domain of eukaryotic RNA polymerase II by P-TEFb
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    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
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    Chromosome-scale assemblies reveal the structural evolution of African cichlid genomes
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  200. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Global epigenetic analysis of BDNF Val66Met mice hippocampus reveals changes in dendrite and spine remodeling genes
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    BET Inhibition Induces HEXIM1- and RAD51-Dependent Conflicts between Transcription and Replication
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    JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells
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    N6-methyladenine DNA Modification in Glioblastoma
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells
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    Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects
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    Next-Generation Sequencing of Cell-Free DNA Extracted From Pleural Effusion Supernatant: Applications and Challenges
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  210. May 2021
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
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    A single-cell analysis of the Arabidopsis vegetative shoot apex
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  217. Apr 2021
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    Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants
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    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    Germline EGFR variants are over-represented in adolescents and young adults (AYA) with adrenocortical carcinoma
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    The origins and consequences of UPF1 variants in pancreatic adenosquamous carcinoma
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  228. Jan 2021
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    Protocol for assaying chromatin accessibility using ATAC-seq in plants
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    QUAKING Regulates Microexon Alternative Splicing of the Rho GTPase Pathway and Controls Microglia Homeostasis
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    SVA retrotransposon insertion in exon of MMR genes results in aberrant RNA splicing and causes Lynch syndrome
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  233. Oct 2020
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    Widespread Transcriptional Readthrough Caused by Nab2 Depletion Leads to Chimeric Transcripts with Retained Introns
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    DNA Methylation Profiling and Genomic Analysis in 20 Children with Short Stature Who Were Born Small for Gestational Age
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    Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma
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  237. Sep 2020
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    Structure-Mediated RNA Decay by UPF1 and G3BP1
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    Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast
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    Long-read only assembly of Drechmeria coniospora genomes reveals widespread chromosome plasticity and illustrates the limitations of current nanopore methods
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    Identification of novel fusion transcripts in meningioma
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    OsNSUN2-Mediated 5-Methylcytosine mRNA Modification Enhances Rice Adaptation to High Temperature
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