112 Matching Annotations
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    Vaginal microbiota transfer ameliorates cesarean-associated neurodevelopmental deficits in mice via N-bc2S1P synthesis on neonatal skin
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    The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
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    Functional genetic screens reveal key pathways instructing the molecular phenotypes of tumor-associated macrophages
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  5. Apr 2026
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    Loss of Ehmt2/G9a function in zebrafish is associated with global deficiency in H3K9 dimethylation, misregulated cell cycle dynamics, and embryonic developmental delay
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    Epigenetic context defines the transcriptional activity of canonical and noncanonical NF-κB signaling in pancreatic cancer
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  8. Mar 2026
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    Condensation of an H3K9me3 methyltransferase complex promotes heritable gene silencing and heterochromatin formation
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  10. Feb 2026
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    Cytoplasmic mRNA decay by the antiviral nuclease RNase L promotes transcriptional repression
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    Cell-free DNA epigenomic profiling enables noninvasive detection and monitoring of translocation renal cell carcinoma
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    C9orf72 hexanucleotide repeat RNA drives transcriptional dysregulation through genome-wide DNA:RNA hybrid G-quadruplexes
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    From degraded to deciphered: Applying ATAC-seq to forensic molecular diagnosis under degradation conditions
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    HIF-2-dependent Regulation of PTHrP and Paraneoplastic Hypercalcemia in Aggressive Clear Cell Renal Cell Carcinoma
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    KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma
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  19. Oct 2025
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    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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  21. Sep 2025
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    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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  24. Aug 2025
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    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer
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  27. Jul 2025
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    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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  32. Jun 2025
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    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus
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  39. Feb 2025
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    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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  42. Jan 2025
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    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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  44. Dec 2024
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    BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia
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  46. Nov 2024
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    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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  48. Oct 2024
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    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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  50. Jul 2024
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    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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  53. Jun 2024
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    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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  59. Apr 2024
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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  62. Mar 2024
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    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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  64. Feb 2024
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    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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  69. Jan 2024
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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  73. Dec 2023
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    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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  76. Nov 2023
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    Selective inhibition of CDK9 in triple negative breast cancer
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    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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  79. Jun 2023
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  82. May 2023
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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  87. Aug 2022
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    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
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    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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  90. Jun 2022
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    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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  93. Mar 2022
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  96. Jan 2022
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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  98. Nov 2021
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    An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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  104. Oct 2021
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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  106. Sep 2021
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    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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  110. Aug 2021
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    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice
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  116. Jul 2021
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    N6-methyladenine DNA Modification in Glioblastoma
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  120. May 2021
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  127. Jan 2021
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  129. Sep 2020
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  135. Jan 2020
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  143. Nov 2018
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  153. Nov 2017
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