78 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    1. scibot 18 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114406

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    sciencedirect.com/science/article/pii/S2211124724007356
  3. Jun 2024
  4. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    1. scibot 06 Jun 2024
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      DOI: 10.1186/s12943-024-02034-7

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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  5. May 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
    3
    1. scibot 30 May 2024
      RRID:SCR_012918

      DOI: 10.1016/j.cell.2024.04.047

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    2. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    3. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
    1
    1. scibot 22 May 2024
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      DOI: 10.1158/2767-9764.CRC-23-0639

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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
    2
    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    2. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
  9. Apr 2024
  10. www.sciencedirect.com www.sciencedirect.com
    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
    1
    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
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    A senescence restriction point acting on chromatin integrates oncogenic signals
    1
    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114044

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    sciencedirect.com/science/article/pii/S2211124724003723
  12. Mar 2024
  13. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
    1
    1. scibot 19 Mar 2024
      RRID:SCR_012918

      DOI: 10.1007/s00414-024-03206-2

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    link.springer.com/article/10.1007/s00414-024-03206-2
  14. Feb 2024
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
    1
    1. scibot 16 Feb 2024
      RRID:SCR_012918

      DOI: 10.1158/0008-5472.CAN-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1186/s13059-023-03161-y

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    link.springer.com/article/10.1186/s13059-023-03161-y
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PHF6 suppresses self-renewal of leukemic stem cells in AML
    1
    1. scibot 02 Feb 2024
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      DOI: 10.1101/2024.01.06.573649

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802281/
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    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
    1
    1. scibot 02 Feb 2024
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    sciencedirect.com/science/article/pii/S1534580724000054
  19. Jan 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
    1
    1. scibot 10 Jan 2024
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      DOI: 10.1158/0008-5472.CAN-22-2712

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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.cmet.2023.12.010

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    sciencedirect.com/science/article/pii/S1550413123004618
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
    1
    1. scibot 06 Jan 2024
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      DOI: 10.1016/j.xgen.2023.100471

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  23. Dec 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.ccell.2023.11.010

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    sciencedirect.com/science/article/pii/S1535610823004014
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
    1
    1. scibot 13 Dec 2023
      RRID:SCR_012918

      DOI: 10.12688/wellcomeopenres.19680.2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10709690/
  26. Nov 2023
  27. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
    1
    1. scibot 25 Nov 2023
      RRID:SCR_012918

      DOI: 10.1038/s41388-023-02892-3

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    nature.com/articles/s41388-023-02892-3
  28. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
    1
    1. scibot 10 Nov 2023
      RRID:SCR_012918

      DOI: 10.12688/wellcomeopenres.19680.1

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    wellcomeopenresearch.org/articles/8-403/v1
  29. Jun 2023
  30. 52.53.155.43 52.53.155.43
    can-22-2712-html.html
    1
    1. scibot 29 Jun 2023
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      DOI: 10.1158/0008-5472.can-22-2712

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    52.53.155.43/726555d37fadfa1ef429cf94df3437d3f13c8b94/can-22-2712-html.html
  31. dx.doi.org dx.doi.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
    1
    1. scibot 10 Jun 2023
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      DOI: 10.1158/2159-8290.CD-22-0825

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    dx.doi.org/10.1158/2159-8290.CD-22-0825
  32. May 2023
  33. 52.53.155.43 52.53.155.43
    bqad083-html.html
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    1. scibot 27 May 2023
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      DOI: 10.1210/endocr/bqad083

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  34. Apr 2023
  35. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
    1
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      DOI: 10.1016/j.molcel.2023.04.005

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    sciencedirect.com/science/article/pii/S1097276523002496
  36. www.sciencedirect.com www.sciencedirect.com
    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
    1
    1. scibot 15 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112373

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    sciencedirect.com/science/article/pii/S2211124723003844
  37. Aug 2022
  38. www.sciencedirect.com www.sciencedirect.com
    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.celrep.2022.111236

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    sciencedirect.com/science/article/pii/S2211124722010531
  39. aacrjournals.org aacrjournals.org
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
    1
    1. scibot 16 Aug 2022
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      DOI: 10.1158/0008-5472.CAN-21-4160

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    aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
  40. Jun 2022
  41. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
    1
    1. scibot 09 Jun 2022
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      DOI: 10.7554/eLife.66909

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    elifesciences.org/articles/66909
  42. www.sciencedirect.com www.sciencedirect.com
    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110889

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    sciencedirect.com/science/article/pii/S2211124722006647
  43. Mar 2022
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
    1
    1. scibot 11 Mar 2022
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      DOI: 10.7554/eLife.71094

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    ncbi.nlm.nih.gov/pmc/articles/PMC8903835/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
    1
    1. scibot 04 Mar 2022
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      DOI: 10.7554/eLife.73358

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    ncbi.nlm.nih.gov/pmc/articles/PMC8849321/
  46. Jan 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
    1
    1. scibot 27 Jan 2022
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      DOI: 10.1016/j.devcel.2021.12.019

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    sciencedirect.com/science/article/pii/S153458072101039X
  48. Nov 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis
    1
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      DOI: 10.1158/2159-8290.CD-20-0336

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    ncbi.nlm.nih.gov/pmc/articles/PMC8591992/
  50. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
    1
    1. scibot 10 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109921

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    sciencedirect.com/science/article/pii/S2211124721013942
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
    1
    1. scibot 09 Nov 2021
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      DOI: 10.1158/1541-7786.MCR-21-0354

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    ncbi.nlm.nih.gov/pmc/articles/PMC8568690/
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    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
    1
    1. scibot 05 Nov 2021
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      DOI: 10.1016/j.cell.2021.10.006

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    sciencedirect.com/science/article/pii/S0092867421011806
  53. www.sciencedirect.com www.sciencedirect.com
    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
    1
    1. scibot 03 Nov 2021
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      DOI: 10.1016/j.celrep.2021.109943

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    sciencedirect.com/science/article/pii/S2211124721014169
  54. Oct 2021
  55. www.sciencedirect.com www.sciencedirect.com
    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
    1
    1. scibot 06 Oct 2021
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      DOI: 10.1016/j.celrep.2021.109776

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    sciencedirect.com/science/article/pii/S2211124721012304
  56. Sep 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1158/2643-3230.bcd-21-0012

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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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  60. Aug 2021
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    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice
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  66. Jul 2021
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    N6-methyladenine DNA Modification in Glioblastoma
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  70. May 2021
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  73. Apr 2021
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    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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  75. Feb 2021
  76. elifesciences.org elifesciences.org
    Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures
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  77. Jan 2021
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    Protocol for assaying chromatin accessibility using ATAC-seq in plants
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  79. Sep 2020
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18
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      DOI: 10.7554/eLife.51325

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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      DOI: 10.1016/j.cell.2020.03.052

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    A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture
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      DOI: 10.7554/eLife.51276

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    Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons
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  85. Jan 2020
  86. www.sciencedirect.com www.sciencedirect.com
    RNA Interactions Are Essential for CTCF-Mediated Genome Organization
    1
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      DOI: 10.1016/j.molcel.2019.08.015

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    Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF
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      DOI: 10.1016/j.celrep.2019.10.106

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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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      DOI: 10.1016/j.immuni.2019.09.021

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    A Unique Epigenomic Landscape Defines Human Erythropoiesis
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    sciencedirect.com/science/article/pii/S2211124719310538
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      DOI: 10.1016/j.cell.2018.12.012

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  93. Nov 2018
  94. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
    1
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  96. www.sciencedirect.com www.sciencedirect.com
    HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6126923/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of m6A/m-RNA Methylation in Stress Response Regulation
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6042962/
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    The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
    1
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  103. Nov 2017
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex
    1
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