100 Matching Annotations
  1. Oct 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR Screen Identifies HDAC3 as a Novel Radiosensitizing Target in Small Cell Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12493205/
  3. Sep 2025
  4. www.sciencedirect.com www.sciencedirect.com
    Requirements for establishment and epigenetic stability of mammalian heterochromatin
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    sciencedirect.com/science/article/pii/S1097276525007105
  5. www.biorxiv.org www.biorxiv.org
    Detection and monitoring of translocation renal cell carcinoma via plasma cell-free epigenomic profiling
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    biorxiv.org/content/10.1101/2025.08.31.673338v1
  6. Aug 2025
  7. www.biorxiv.org www.biorxiv.org
    Genetic and Epigenetic Reprogramming of Transposable Elements Drives ecDNA-Mediated Metastatic Prostate Cancer
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    biorxiv.org/content/10.1101/2025.08.08.668693v1
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Interplay of YEATS2 and GCDH regulates histone crotonylation and drives EMT in head and neck cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12352869/
  9. Jul 2025
  10. www.sciencedirect.com www.sciencedirect.com
    β-catenin functions as a molecular adapter for disordered cBAF interactions
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    sciencedirect.com/science/article/pii/S1097276525005763
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiomics uncovers the epigenomic and transcriptomic response to viral and bacterial stimulation in turbot
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    pmc.ncbi.nlm.nih.gov/articles/PMC12263217/
  12. 52.53.155.43 52.53.155.43
    1-s2.0-S0016508525057324-main-html.html
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    The costimulatory molecule ICOS limits memory-like properties and function of exhausted PD-1+CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002481
  14. Jun 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal binding protein 2 interacts with JUNB to control macrophage inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149670/
  16. 52.53.155.43 52.53.155.43
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  18. Mar 2025
  19. www.sciencedirect.com www.sciencedirect.com
    Orchestration of pluripotent stem cell genome reactivation during mitotic exit
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    sciencedirect.com/science/article/pii/S2211124725002578
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus
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    pmc.ncbi.nlm.nih.gov/articles/PMC11928027/
  21. Feb 2025
  22. aacrjournals.org aacrjournals.org
    Epigenome reprogramming through H3K27 and H3K4 trimethylation as a resistance mechanism to DNA methylation inhibition in BRAFV600E-mutated colorectal cancer
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    aacrjournals.org/clincancerres/article/30/22/5166/749574/Epigenome-Reprogramming-Through-H3K27-and-H3K4
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone H4 acetylation differentially modulates proliferation in adult oligodendrocyte progenitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11318668/
  24. Jan 2025
  25. www.sciencedirect.com www.sciencedirect.com
    KDM6B-dependent epigenetic programming of uterine fibroblasts in early pregnancy regulates parturition timing in mice
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    sciencedirect.com/science/article/pii/S0092867424014326
  26. Dec 2024
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BPDCN MYB fusions regulate cell cycle genes, impair differentiation, and induce myeloid–dendritic cell leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC11665559/
  28. Nov 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction
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    pmc.ncbi.nlm.nih.gov/articles/PMC11535398/
  30. Oct 2024
  31. aacrjournals.org aacrjournals.org
    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  32. Jul 2024
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    The primitive endoderm supports lineage plasticity to enable regulative development
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    sciencedirect.com/science/article/pii/S0092867424005956
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11290356/
  35. Jun 2024
  36. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  37. May 2024
  38. www.sciencedirect.com www.sciencedirect.com
    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
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    sciencedirect.com/science/article/pii/S0092867424004732
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacologic Targeting of Histone H3K27 Acetylation/BRD4-dependent Induction of ALDH1A3 for Early-phase Drug Tolerance of Gastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11104289/
  40. www.sciencedirect.com www.sciencedirect.com
    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    sciencedirect.com/science/article/pii/S0092867424004483
  41. Apr 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    sciencedirect.com/science/article/pii/S2211124724003930
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    sciencedirect.com/science/article/pii/S2211124724003723
  44. Mar 2024
  45. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    link.springer.com/article/10.1007/s00414-024-03206-2
  46. Feb 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
  48. genomebiology.biomedcentral.com genomebiology.biomedcentral.com
    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    genomebiology.biomedcentral.com/articles/10.1186/s13059-023-03161-y
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PHF6 suppresses self-renewal of leukemic stem cells in AML
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    ncbi.nlm.nih.gov/pmc/articles/PMC10802281/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PUF partner interactions at a conserved interface shape the RNA-binding landscape and cell fate in Caenorhabditis elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11253550/
  51. Jan 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
  53. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    sciencedirect.com/science/article/pii/S1550413123004618
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  55. Dec 2023
  56. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610823004014
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10709690/
  58. Nov 2023
  59. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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    nature.com/articles/s41388-023-02892-3
  60. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    wellcomeopenresearch.org/articles/8-403/v1
  61. Jun 2023
  62. 52.53.155.43 52.53.155.43
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  63. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
  64. May 2023
  65. 52.53.155.43 52.53.155.43
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  66. Apr 2023
  67. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    sciencedirect.com/science/article/pii/S1097276523002496
  68. www.sciencedirect.com www.sciencedirect.com
    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    sciencedirect.com/science/article/pii/S2211124723003844
  69. Aug 2022
  70. www.sciencedirect.com www.sciencedirect.com
    The sage genome provides insight into the evolutionary dynamics of diterpene biosynthesis gene cluster in plants
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    sciencedirect.com/science/article/pii/S2211124722010531
  71. aacrjournals.org aacrjournals.org
    Developmental pathways are epigenetically reprogrammed during lung cancer brain metastasis
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    aacrjournals.org/cancerres/article/82/15/2692/707331/Developmental-Pathways-Are-Epigenetically
  72. Jun 2022
  73. elifesciences.org elifesciences.org
    Dnmt3a knockout in excitatory neurons impairs postnatal synapse maturation and increases the repressive histone modification H3K27me3
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    elifesciences.org/articles/66909
  74. www.sciencedirect.com www.sciencedirect.com
    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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    sciencedirect.com/science/article/pii/S2211124722006647
  75. Mar 2022
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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    ncbi.nlm.nih.gov/pmc/articles/PMC8903835/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A test of the pioneer factor hypothesis using ectopic liver gene activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8849321/
  78. Jan 2022
  79. www.sciencedirect.com www.sciencedirect.com
    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    sciencedirect.com/science/article/pii/S153458072101039X
  80. Nov 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An epigenetic mechanism underlying chromosome 17p deletion-driven tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC8591992/
  82. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC8568690/
  84. www.sciencedirect.com www.sciencedirect.com
    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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    Acute depletion of the ARID1A subunit of SWI/SNF complexes reveals distinct pathways for activation and repression of transcription
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    sciencedirect.com/science/article/pii/S2211124721014169
  86. Oct 2021
  87. www.sciencedirect.com www.sciencedirect.com
    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    sciencedirect.com/science/article/pii/S2211124721012304
  88. Sep 2021
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  90. www.sciencedirect.com www.sciencedirect.com
    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    sciencedirect.com/science/article/pii/S1534580721006821
  91. www.sciencedirect.com www.sciencedirect.com
    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
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    sciencedirect.com/science/article/pii/S1097276521006961
  92. Aug 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7401316/
  94. www.sciencedirect.com www.sciencedirect.com
    Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding
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    sciencedirect.com/science/article/pii/S0896627321005067
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC7450110/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6408623/
  97. elifesciences.org elifesciences.org
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    elifesciences.org/articles/21883
  98. Jul 2021
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    N6-methyladenine DNA Modification in Glioblastoma
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  102. May 2021
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Chromatin Accessibility Dynamics and a Hierarchical Transcriptional Regulatory Network Structure for Plant Somatic Embryogenesis
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  105. Apr 2021
  106. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
  107. Feb 2021
  108. elifesciences.org elifesciences.org
    Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures
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    elifesciences.org/articles/43257
  109. Jan 2021
  110. www.sciencedirect.com www.sciencedirect.com
    Protocol for assaying chromatin accessibility using ATAC-seq in plants
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    sciencedirect.com/science/article/pii/S2666166720302768
  111. Sep 2020
  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of zebrafish periderm enhancers facilitates identification of a regulatory variant near human KRT8/18
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    ncbi.nlm.nih.gov/pmc/articles/PMC7039683/
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC7064337/
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    Heterochromatin-Driven Nuclear Softening Protects the Genome against Mechanical Stress-Induced Damage
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture
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    ncbi.nlm.nih.gov/pmc/articles/PMC6948952/
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    Genomic Rewiring of SOX2 Chromatin Interaction Network during Differentiation of ESCs to Postmitotic Neurons
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    sciencedirect.com/science/article/pii/S2405471220301885
  117. Jan 2020
  118. www.sciencedirect.com www.sciencedirect.com
    RNA Interactions Are Essential for CTCF-Mediated Genome Organization
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    Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF
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    sciencedirect.com/science/article/pii/S2211124719314391
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    Genome-wide Analyses of Chromatin State in Human Mast Cells Reveal Molecular Drivers and Mediators of Allergic and Inflammatory Diseases
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    A Unique Epigenomic Landscape Defines Human Erythropoiesis
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    The Nuclear Receptor PPARγ Controls Progressive Macrophage Polarization as a Ligand-Insensitive Epigenomic Ratchet of Transcriptional Memory
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    The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
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    Layer-specific chromatin accessibility landscapes reveal regulatory networks in adult mouse visual cortex
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