71 Matching Annotations
  1. Last 7 days
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    <fc>PBMC circRNA</fc> Profiles Distinguish Atypical From Idiopathic Parkinsonism and Track Clinical Severity Across Syndromes
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    onlinelibrary.wiley.com/doi/10.1111/jnc.70519
  3. Jul 2026
  4. www.biorxiv.org www.biorxiv.org
    Tumoral switch in NUMB splicing changes essential transcription pathways and induces malignant properties in tumour cells
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    biorxiv.org/content/10.64898/2026.05.15.725391v1
  5. May 2026
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    Translating transcriptomics analysis into diagnostic workflows: clinical variant identification and interpretation in hypothesis-driven and hypothesis-free approaches
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    sciencedirect.com/science/article/pii/S2352396426001957
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial Transcriptomics Reveals Location-Specific Tumor Cell Subtypes and Signaling within Multifocal Small Intestinal Neuroendocrine Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC13176825/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    scSurvival: Single-Cell Survival Analysis of Clinical Cancer Cohort Data at Cellular Resolution
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133615/
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    Adenosine A2B Receptor Promotes Tumor Progression and Metastases in Undifferentiated Pleomorphic Sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC13133607/
  10. Mar 2026
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    Interleukin-30 promotes melanoma spreading and triggers LAG-3 expression and T cell exhaustion
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    sciencedirect.com/science/article/pii/S0753332226002167
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    RORγt Inhibition Reduces Pro-Tumor Inflammation and Decreases Tumor Growth in Experimental Models of Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12288671/
  13. Feb 2026
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12925509/
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    Progranulin promotes glioma progression via interaction with cathepsin D and serves as a diagnostic and prognostic biomarker
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    pmc.ncbi.nlm.nih.gov/articles/PMC12917043/
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    Integrative CRISPR Screening and RNA Analyses Discover an Essential Role for PUF60 Interactions with 3' Splice Sites in Cancer Progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12911328/
  17. Oct 2025
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    Pan-cancer analysis of RNA expression signatures associated with cancer tissue architecture
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    nature.com/articles/s41416-025-03233-9
  19. Sep 2025
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    Robust and adaptive non-parametric tests for detecting general distributional shifts in gene expression
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    sciencedirect.com/science/article/pii/S2667237525001833
  21. Aug 2025
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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.70107
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    SLC4A11 is a targetable marker correlated with therapeutic responses in ovarian cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12309138/
  24. Jun 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12183228/
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    Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
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  27. Mar 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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    The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis
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    biorxiv.org/content/10.1101/2025.03.18.644053v1
  30. Feb 2025
  31. www.sciencedirect.com www.sciencedirect.com
    Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants
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    sciencedirect.com/science/article/pii/S2666979X2500031X
  32. Jan 2025
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    NIPAL1 as a prognostic biomarker associated with pancreatic adenocarcinoma progression and immune infiltration
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    link.springer.com/article/10.1186/s12885-025-13567-5
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    RECQL4 affects MHC class II‐mediated signalling and favours an immune‐evasive signature that limits response to immune checkpoint inhibitor therapy in patients with malignant melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11734436/
  35. Nov 2024
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
  37. Sep 2024
  38. www.sciencedirect.com www.sciencedirect.com
    β-chitosan attenuates hepatic macrophage-driven inflammation and reverses aging-related cognitive impairment
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural analysis of genomic and proteomic signatures reveal dynamic expression of intrinsically disordered regions in breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11416222/
  40. May 2024
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    Genome sequence analyses identify novel risk loci for multiple system atrophy
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    sciencedirect.com/science/article/pii/S089662732400240X
  42. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  43. Apr 2024
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    Korea4K: whole genome sequences of 4,157 Koreans with 107 phenotypes derived from extensive health check-ups
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    academic.oup.com/gigascience/article/doi/10.1093/gigascience/giae014/7646332
  45. Feb 2024
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    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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    nature.com/articles/s41467-024-45067-8
  48. Jan 2024
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  50. Dec 2023
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  52. Nov 2023
  53. www.sciencedirect.com www.sciencedirect.com
    Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
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    sciencedirect.com/science/article/pii/S2211124723013633
  54. Sep 2023
  55. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    IGF2BP2 promotes ovarian cancer growth and metastasis by upregulating CKAP2L protein expression in an m6A-dependent manner
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202202145RRR
  56. Aug 2023
  57. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    biorxiv.org/content/10.1101/2023.08.21.553157v1
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    Identification of Novel Intronic SNPs in Transporter Genes Associated with Metformin Side Effects
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    mdpi.com/2073-4425/14/8/1609
  59. Jul 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
  61. May 2023
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification related to immunogenic cell death predicts prognosis, immune microenvironment characteristics, and response to immunotherapy in lower-grade gliomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154552/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10151192/
  64. Apr 2023
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10108886/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purinergic GPCR-integrin interactions drive pancreatic cancer cell invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10069867/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10064239/
  68. Feb 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort
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    ncbi.nlm.nih.gov/pmc/articles/PMC9896026/
  70. Nov 2022
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Using machine learning to find genes associated with sudden death
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    ncbi.nlm.nih.gov/pmc/articles/PMC9641215/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
  73. Sep 2022
  74. www.sciencedirect.com www.sciencedirect.com
    A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation
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    sciencedirect.com/science/article/pii/S0960982222013811
  75. Aug 2022
  76. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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    aacrjournals.org/cancerres/article/82/14/2576/706950/Proteomic-Mapping-and-Targeting-of-Mitotic
  77. Jul 2022
  78. www.medrxiv.org www.medrxiv.org
    Association between the LRP1B and APOE loci and the development of Parkinson’s disease dementia
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    medrxiv.org/content/10.1101/2022.05.23.22275465v1
  79. Apr 2022
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A conditional gene-based association framework integrating isoform-level eQTL data reveals new susceptibility genes for schizophrenia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9005191/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated MACC1 Expression in Colorectal Cancer Is Driven by Chromosomal Instability and Is Associated with Molecular Subtype and Worse Patient Survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC8997143/
  82. Dec 2021
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals
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    ncbi.nlm.nih.gov/pmc/articles/PMC8406447/
  84. Nov 2021
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A sex-specific evolutionary interaction between ADCY9 and CETP
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  86. www.sciencedirect.com www.sciencedirect.com
    Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas
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    sciencedirect.com/science/article/pii/S2589004221012918
  87. Oct 2021
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    Role of miR-2392 in driving SARS-CoV-2 infection
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    sciencedirect.com/science/article/pii/S2211124721013036
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human genetic analyses of organelles highlight the nucleus in age-related trait heritability
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    ncbi.nlm.nih.gov/pmc/articles/PMC8476128/
  90. Sep 2021
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    Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines
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    sciencedirect.com/science/article/pii/S240547122100329X
  92. Aug 2021
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC6542586/
  94. Jul 2021
  95. f1000research.com f1000research.com
    F1000Research Article: PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals.
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    f1000research.com/articles/10-570
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The magnesium transporter NIPAL1 is a pancreatic islet–expressed protein that conditionally impacts insulin secretion
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    ncbi.nlm.nih.gov/pmc/articles/PMC7380176/
  97. May 2021
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    Germline genetic contribution to the immune landscape of cancer
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    sciencedirect.com/science/article/pii/S1074761321000340
  99. Apr 2021
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    Analysis of Brugada syndrome loci reveals that fine-mapping clustered GWAS hits enhances the annotation of disease-relevant variants
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    sciencedirect.com/science/article/pii/S2666379121000665
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    Immunogenomic Landscape of Hematological Malignancies
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    sciencedirect.com/science/article/pii/S1535610820302750
  102. Sep 2020
  103. www.sciencedirect.com www.sciencedirect.com
    Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness
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  104. www.frontiersin.org www.frontiersin.org
    Functional Genetic Polymorphisms in the IL1RL1–IL18R1 Region Confer Risk for Ocular Behçet’s Disease in a Chinese Han Population
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    frontiersin.org/article/10.3389/fgene.2020.00645/full
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7238334/
  106. www.hindawi.com www.hindawi.com
    Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer
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    hindawi.com/journals/dm/2020/8974793/
  107. www.nature.com www.nature.com
    Immune expression signatures as candidate prognostic biomarkers of age and gender survival differences in cutaneous melanoma
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    nature.com/articles/s41598-020-69082-z
  108. Jan 2020
  109. www.sciencedirect.com www.sciencedirect.com
    DUX4 Suppresses MHC Class I to Promote Cancer Immune Evasion and Resistance to Checkpoint Blockade
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    sciencedirect.com/science/article/pii/S1534580719305295
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    Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks
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    Untitled document
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    sciencedirect.com/science/article/pii/S0960982218314702
  112. Nov 2018
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    Fast-Evolving Human-Specific Neural Enhancers Are Associated with Aging-Related Diseases
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