310 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TERT Promoter is Polycomb-Repressed in Neuroblastoma Cells with Long Telomeres
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    1. scibot 27 Jun 2024
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      DOI: 10.1158/2767-9764.CRC-22-0287

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    ncbi.nlm.nih.gov/pmc/articles/PMC11188873/
  3. Jun 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma
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    1. scibot 20 Jun 2024
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      DOI: 10.7554/eLife.83527

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    ncbi.nlm.nih.gov/pmc/articles/PMC11178360/
  5. molecular-cancer.biomedcentral.com molecular-cancer.biomedcentral.com
    Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients
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    1. scibot 06 Jun 2024
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      DOI: 10.1186/s12943-024-02034-7

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    molecular-cancer.biomedcentral.com/articles/10.1186/s12943-024-02034-7
  6. May 2024
  7. www.sciencedirect.com www.sciencedirect.com
    Heterochromatic 3D genome organization is directed by HP1a- and H3K9-dependent and independent mechanisms
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    1. scibot 30 May 2024
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      DOI: 10.1016/j.molcel.2024.05.002

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    sciencedirect.com/science/article/pii/S1097276524003952
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    Reciprocal conversion between annual and polycarpic perennial flowering behavior in the Brassicaceae
    3
    1. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    2. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    3. scibot 30 May 2024
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      DOI: 10.1016/j.cell.2024.04.047

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    sciencedirect.com/science/article/pii/S0092867424004732
  9. 52.53.155.43 52.53.155.43
    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
    2
    1. scibot 29 May 2024
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      DOI: 10.1101/2024.03.08.583864

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      DOI: 10.1101/2024.03.08.583864

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    52.53.155.43/18a5f967080cacc79c7f5cca9d1b0be744600675/2024.03.08.583864v1.full-html.html
  10. 52.53.155.43 52.53.155.43
    mcr-23-0295-html.html
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    1. scibot 23 May 2024
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      DOI: 10.1158/1541-7786.mcr-23-0295

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    52.53.155.43/d0655220046c67483bcefd25ef239fc58ad80cdd/mcr-23-0295-html.html
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    1. scibot 23 May 2024
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      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
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    Osr2 functions as a biomechanical checkpoint to aggravate CD8+ T cell exhaustion in tumor
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.cell.2024.04.023

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      DOI: 10.1016/j.cell.2024.04.023

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    sciencedirect.com/science/article/pii/S0092867424004483
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    Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.stem.2024.04.015

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    sciencedirect.com/science/article/pii/S1934590924001425
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
    1
    1. scibot 07 May 2024
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      DOI: 10.1016/j.molcel.2024.04.007

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    sciencedirect.com/science/article/pii/S1097276524002855
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    MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons
    1
    1. scibot 02 May 2024
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      DOI: 10.1016/j.neuron.2024.04.007

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    sciencedirect.com/science/article/pii/S0896627324002459
  16. Apr 2024
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced bovine genome annotation through integration of transcriptomics and epi-transcriptomics datasets facilitates genomic biology
    1
    1. scibot 20 Apr 2024
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      DOI: 10.1093/gigascience/giae019

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    ncbi.nlm.nih.gov/pmc/articles/PMC11020238/
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    1. scibot 05 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114065

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    sciencedirect.com/science/article/pii/S2211124724003930
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    1. scibot 04 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114044

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    sciencedirect.com/science/article/pii/S2211124724003723
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    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
    1
    1. scibot 03 Apr 2024
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      DOI: 10.1016/j.xcrm.2024.101472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  21. Mar 2024
  22. link.springer.com link.springer.com
    From degraded to deciphered: ATAC-seq’s application potential in forensic diagnosis
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    1. scibot 19 Mar 2024
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      DOI: 10.1007/s00414-024-03206-2

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    link.springer.com/article/10.1007/s00414-024-03206-2
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    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
    1
    1. scibot 05 Mar 2024
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      DOI: 10.1016/j.immuni.2024.02.004

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    sciencedirect.com/science/article/pii/S1074761324000803
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
    1
    1. scibot 01 Mar 2024
      RRID:SCR_00652

      DOI: 10.1016/j.cmet.2023.12.010

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    sciencedirect.com/science/article/pii/S1550413123004618
  25. Feb 2024
  26. 52.53.155.43 52.53.155.43
    can-23-1129-html.html
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    1. scibot 23 Feb 2024
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      DOI: 10.1158/0008-5472.can-23-1129

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    52.53.155.43/f18faff86a38ad159824c95dcf032e1a8bb0e968/133-html.html
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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    1. scibot 16 Feb 2024
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      DOI: 10.1158/0008-5472.CAN-23-0539

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527051/
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    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
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      DOI: 10.1016/j.devcel.2024.01.024

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    sciencedirect.com/science/article/pii/S1534580724000443
  29. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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    1. scibot 09 Feb 2024
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      DOI: 10.1101/2023.12.10.570854

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    biorxiv.org/content/10.1101/2023.12.10.570854v1
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson’s Disease Risk Enhancers in Microglia
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.isci.2024.108921

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845915/
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
    1
    1. scibot 07 Feb 2024
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      DOI: 10.1186/s13059-023-03161-y

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    link.springer.com/article/10.1186/s13059-023-03161-y
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
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      DOI: 10.1158/2767-9764.CRC-23-0358

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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
    2
    1. scibot 02 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113715

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      DOI: 10.1016/j.celrep.2024.113715

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    sciencedirect.com/science/article/pii/S2211124724000433
  34. Jan 2024
  35. www.nature.com www.nature.com
    Cell-type-directed design of synthetic enhancers
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      DOI: 10.1038/s41586-023-06936-2

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    nature.com/articles/s41586-023-06936-2
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
    1
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      DOI: 10.1101/2023.12.20.570481

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    ncbi.nlm.nih.gov/pmc/articles/PMC10769259/
  37. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Genomic exploration of the targets of FOXL2 and ESR2 unveils their implication in cell migration, invasion, and adhesion
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      DOI: 10.1096/fj.202002444R

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002444R
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    Inherited blood cancer predisposition through altered transcription elongation
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      DOI: 10.1016/j.cell.2023.12.016

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    sciencedirect.com/science/article/pii/S009286742301348X
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    An exhausted-like microglial population accumulates in aged and APOE4 genotype Alzheimer’s brains
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    sciencedirect.com/science/article/pii/S1074761323005320
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
    1
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      DOI: 10.1016/j.cmet.2023.12.010

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    sciencedirect.com/science/article/pii/S1550413123004618
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation
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      DOI: 10.1016/j.xgen.2023.100471

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794847/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
    1
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      DOI: 10.1158/0008-5472.CAN-23-1129

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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  43. Dec 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
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      DOI: 10.1016/j.isci.2023.108537

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    sciencedirect.com/science/article/pii/S2589004223026147
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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      DOI: 10.1016/j.ccell.2023.11.010

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    Blimp-1 and c-Maf regulate  Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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  48. 52.53.155.43 52.53.155.43
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  49. Nov 2023
  50. www.nature.com www.nature.com
    Selective inhibition of CDK9 in triple negative breast cancer
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  51. wellcomeopenresearch.org wellcomeopenresearch.org
    Blimp-1 and c-Maf regulate Il10 and negatively regulate common and unique proinflammatory gene networks in IL-12 plus IL-27-driven T helper-1 cells
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  52. www.sciencedirect.com www.sciencedirect.com
    Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
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    Active maintenance of CD8+ T cell naivety through regulation of global genome architecture
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  54. Oct 2023
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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  59. Sep 2023
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    Perturbations in 3D genome organization can promote acquired drug resistance
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  61. Aug 2023
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    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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  64. Jul 2023
  65. www.sciencedirect.com www.sciencedirect.com
    The stability of the myelinating oligodendrocyte transcriptome is regulated by the nuclear lamina
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-level repressive histone marks fine-tune gene transcription in neural stem cells
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  69. Jun 2023
  70. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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    5-Azacytidine- and retinoic-acid-induced reprogramming of DCCs into dormancy suppresses metastasis via restored TGF-β-SMAD4 signaling
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  72. May 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos
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  75. Apr 2023
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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    Active maintenance of CD8+ T cell naïvety through regulation of global genome architecture
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWI/SNF Blockade Disrupts PU.1-Directed Enhancer Programs in Normal Hematopoietic Cells and Acute Myeloid Leukemia
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    Asparagine starvation suppresses histone demethylation through iron depletion
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  83. Mar 2023
  84. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MeCP2 regulates Gdf11, a dosage-sensitive gene critical for neurological function
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  87. Feb 2023
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    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
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    Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma
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  90. Jan 2023
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    SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis
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  92. Dec 2022
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    Prevalent and dynamic binding of the cell cycle checkpoint kinase Rad53 to gene promoters
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    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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  95. Nov 2022
  96. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    Essential role of MESP1-RING1A complex in cardiac differentiation
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    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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  99. Oct 2022
  100. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
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  101. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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  102. Sep 2022
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In Vivo Genome-Wide CRISPR Activation Screening Identifies Functionally Important Long Noncoding RNAs in Hepatocellular Carcinoma
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
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  106. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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  109. Jun 2022
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    Inflammaging is driven by upregulation of innate immune receptors and systemic interferon signaling and is ameliorated by dietary restriction
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    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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    Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
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  116. Apr 2022
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    An adult-stage transcriptional program for survival of serotonergic connectivity
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    HNF4A modulates glucocorticoid action in the liver
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    Presence of H3K4me3 on Paternally Expressed Genes of the Paternal Genome From Sperm to Implantation
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  120. Mar 2022
  121. elifesciences.org elifesciences.org
    Novel insights from a multiomics dissection of the Hayflick limit
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    Placental uptake and metabolism of 25(OH)vitamin D determine its activity within the fetoplacental unit
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  123. aacrjournals.org aacrjournals.org
    EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma
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    A test of the pioneer factor hypothesis using ectopic liver gene activation
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    A genetic compensatory mechanism regulated by Jun and Mef2d modulates the expression of distinct class IIa Hdacs to ensure peripheral nerve myelination and repair
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  126. Feb 2022
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    HiCAR is a robust and sensitive method to analyze open-chromatin-associated genome organization
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    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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    Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories
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    Uncovering the mesendoderm gene regulatory network through multi-omic data integration
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  131. Jan 2022
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
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    Establishment of developmental gene silencing by ordered polycomb complex recruitment in early zebrafish embryos
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    Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response
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    PRC1 sustains the integrity of neural fate in the absence of PRC2 function
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    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
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    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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  139. Dec 2021
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    PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals
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    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
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    Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
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  144. Nov 2021
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    Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins
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  146. www.sciencedirect.com www.sciencedirect.com
    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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  160. Aug 2021
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    Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia
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    A composite DNA element that functions as a maintainer required for epigenetic inheritance of heterochromatin
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    Glucocorticoid Receptor–Tethered Mineralocorticoid Receptors Increase Glucocorticoid-Induced Transcriptional Responses
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    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
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    Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
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    Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia
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    Landscape of histone modifications in a sponge reveals the origin of animal cis-regulatory complexity
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  173. Jul 2021
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    Novel cell adhesion/migration pathways are predictive markers of HDAC inhibitor resistance in cutaneous T cell lymphoma
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    HUMAN TROPHOBLAST DIFFERENTIATION IS ASSOCIATED WITH PROFOUND GENE REGULATORY AND EPIGENETIC CHANGES
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    Chromatin Environment and Cellular Context Specify Compensatory Activity of Paralogous MEF2 Transcription Factors
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    Mapping the Global Chromatin Connectivity Network for Sox2 Function in Neural Stem Cell Maintenance
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    Transcriptional Burst Initiation and Polymerase Pause Release Are Key Control Points of Transcriptional Regulation
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    Enhancer Architecture and Essential Core Regulatory Circuitry of Chronic Lymphocytic Leukemia
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    Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors
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    Gain of CTCF-Anchored Chromatin Loops Marks the Exit from Naive Pluripotency
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    Acetylation of Cytidine in mRNA Promotes Translation Efficiency
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    Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition
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    A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis
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    MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis
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    N6-methyladenine DNA Modification in Glioblastoma
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    SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcing Distinct Chromatin States
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    ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia
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    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
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    Super-Enhancer-Mediated RNA Processing Revealed by Integrative MicroRNA Network Analysis
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    Genome-wide analysis of the H3K27me3 epigenome and transcriptome in Brassica rapa
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  196. f1000research.com f1000research.com
    F1000Research Article: PEGS: An efficient tool for gene set enrichment within defined sets of genomic intervals.
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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  198. Jun 2021
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    Protocol for using heterologous spike-ins to normalize for technical variation in chromatin immunoprecipitation
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  200. May 2021
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    Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity
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    Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets
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    Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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    A Prion-like Domain in Transcription Factor EBF1 Promotes Phase Separation and Enables B Cell Programming of Progenitor Chromatin
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  208. Apr 2021
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    5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease
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    Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells
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    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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    Evidence for additive and synergistic action of mammalian enhancers during cell fate determination
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  213. Mar 2021
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    Human ORC/MCM density is low in active genes and correlates with replication time but does not delimit initiation zones
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    Genomic exploration of the targets of FOXL2 and ESR2 unveils their implication in cell migration, invasion, and adhesion
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    Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
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    HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration
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    Convergent organization of aberrant MYB complex controls oncogenic gene expression in acute myeloid leukemia
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  220. Feb 2021
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    The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages
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    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development
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    The glucocorticoid receptor recruits the COMPASS complex to regulate inflammatory transcription at macrophage enhancers
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  224. Jan 2021
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    Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis
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    The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals
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    Re-expression of SMARCA4/BRG1 in small cell carcinoma of ovary, hypercalcemic type (SCCOHT) promotes an epithelial-like gene signature through an AP-1-dependent mechanism
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  228. Dec 2020
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    Lineage-Resolved Enhancer and Promoter Usage during a Time Course of Embryogenesis
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  230. Sep 2020
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    Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua
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    Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance
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