848 Matching Annotations
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    Identification of hypoxic macrophages in glioblastoma with therapeutic potential for vasculature normalization
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    Selective vulnerability of the ventral hippocampus-prelimbic cortex axis parvalbumin interneuron network underlies learning deficits of fragile X mice
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  4. Apr 2024
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    PALB2-mutated human mammary cells display a broad spectrum of morphological and functional abnormalities induced by increased TGFβ signaling
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    The regulation of enteric neuron connectivity by Semaphorin 5A is affected by the autism-associated S956G missense mutation
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    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
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    Faa1 membrane binding drives positive feedback in autophagosome biogenesis via fatty acid activation
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    Spatial organization and functions of Chk1 activation by TopBP1 biomolecular condensates
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    Osteoclast-specific Plastin 3 knockout in mice fail to develop osteoporosis despite dramatic increased osteoclast resorption activity
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  11. Mar 2024
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    Villus myofibroblasts are developmental and adult progenitors of mammalian gut lymphatic musculature
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    The endogenous calpain inhibitor calpastatin attenuates axon degeneration in murine Guillain‐Barré syndrome
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    The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases
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    Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping protein critical for proper cell differentiation
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    To live free or being a parasite: The optimal foraging behavior may favor the evolution of entomopathogenic nematodes
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    Kdm1a safeguards the topological boundaries of PRC2-repressed genes and prevents aging-related euchromatinization in neurons
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    LncRNA Litchi is a Regulator for Harmonizing Maturity and Resilient Functionality in Spinal Motor Neurons
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    Ly6C+ monocytes in the skin promote systemic alphavirus dissemination
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    TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis
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    Collective cell migration relies on PPP1R15-mediated regulation of the endoplasmic reticulum stress response
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    Neuronal reprogramming of mouse and human fibroblasts using transcription factors involved in suprachiasmatic nucleus development
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    Sperm induction of somatic cell-cell fusion as a novel functional test
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    EHBP1 is critically involved in dendritic arbor formation and is coupled to factors promoting actin filament formation
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    Hair cell regeneration, reinnervation, and restoration of hearing thresholds in the avian hearing organ
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    Proximity proteomics reveals UCH-L1 as an essential regulator of NLRP3 mediated IL-1β production in human macrophages and microglia
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    The lateral habenula is required for maternal behavior in the mouse dam
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      DOI: 10.1101/2024.02.12.577842

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    IL-37d enhances COP1-mediated C/EBPβ degradation to suppress spontaneous neutrophil migration and tumor progression
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    A Comparative Biochemical and Pathological Evaluation of Brain Samples from Knock-In Murine Models of Gaucher Disease
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      DOI: 10.3390/ijms25031827

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    Perineuronal nets in the rat medial prefrontal cortex alter hippocampal-prefrontal oscillations and reshape cocaine self-administration memories
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    NMDAR Phosphoproteome Controls Synaptic Growth and Learning
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    O-GlcNAc forces an α-synuclein amyloid strain with notably diminished seeding and pathology
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    LDO proteins and Vac8 form a vacuole-lipid droplet contact site to enable starvation-induced lipophagy in yeast
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    Influenza A virus propagation requires the activation of the unfolded protein response and the accumulation of insoluble protein aggregates
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  36. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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      DOI: 10.1038/s41467-024-45067-8

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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NG2 Glia Reprogramming Induces Robust Axonal Regeneration After Spinal Cord Injury
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    Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice
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    Midbrain neurons important for the production of mouse ultrasonic vocalizations are not required for distress calls
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    Glia trigger endocytic clearance of axonal proteins to promote rodent myelination
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    Specific prostaglandins are produced in the migratory cells and the surrounding substrate to promote Drosophila border cell migration
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    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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    A Novel Macrolide–Del-1 Axis to Regenerate Bone in Old Age
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    Mapping of multiple neurotransmitter receptor subtypes and distinct protein complexes to the connectome
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    Morphoelectric and transcriptomic divergence of the layer 1 interneuron repertoire in human versus mouse neocortex
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    Cortical somatostatin interneuron subtypes form cell-type-specific circuits
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    FBXW7-loss sensitizes cells to ATR inhibition through induced mitotic catastrophe
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    An essential signaling cascade for avian auditory hair cell regeneration
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    FEZ1 participates in human embryonic brain development by modulating neuronal progenitor subpopulation specification and migration
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    An outer membrane determinant for RNA phage genome entry in Pseudomonas aeruginosa
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    Ratcheted transport and sequential assembly of the yeast telomerase RNP
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    Multipotent progenitors instruct ontogeny of the superior colliculus
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    Interleukin-30 subverts prostate cancer-endothelium crosstalk by fostering angiogenesis and activating immunoregulatory and oncogenic signaling pathways
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    Phylogenetic analyses reveal multiple new stem-boring Tetramesa taxa (Hymenoptera: Eurytomidae): implications for the biological control of invasive African grasses
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    Development and validation of an expanded antibody toolset that captures alpha-synuclein pathological diversity in Lewy body diseases
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    Blockage of the fractalkine pathway reduces hyperalgesia and prevents morphological glial alterations—Comparison between inflammatory and neuropathic orofacial pain in male rats
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    Absence of paresthesia during high-rate spinal cord stimulation reveals importance of synchrony for sensations evoked by electrical stimulation
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    The olfactory working memory capacity paradigm: A more sensitive and robust method of assessing cognitive function in male 5XFAD mice
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    Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson’s disease
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    ADP ribosylation factor 4 (Arf4) regulates radial migration through N-cadherin trafficking during cerebral cortical development
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    IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development
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    Primary cilia control oligodendrocyte precursor cell proliferation in white matter injury via Hedgehog-independent CREB signaling
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    Single-cell transcriptomics illuminates regulatory steps driving anterior-posterior patterning of Drosophila embryonic mesoderm
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    Spinal afferent innervation in flat-mounts of the rat stomach: anterograde tracing
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    Confocal Imaging and 3D Reconstruction to Determine How Genetic Perturbations Impact Presynaptic Morphology at the Mouse Calyx of Held
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    GABAergic signaling shapes multiple aspects of Drosophila courtship motor behavior
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    Negative valence encoding in the lateral entorhinal cortex during aversive olfactory learning
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    High-volume hybridoma sequencing on the NeuroMabSeq platform enables efficient generation of recombinant monoclonal antibodies and scFvs for neuroscience research
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    Neutrophil extracellular traps enhance S. aureus skin colonization by oxidative stress induction and downregulation of epidermal barrier genes
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    Dopaminergic neurons dynamically update sensory values during olfactory maneuver
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    Adenosine A2A receptor is a tumor suppressor of NASH-associated hepatocellular carcinoma
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    The efferent connections of the orbitofrontal, posterior parietal, and insular cortex of the rat brain
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Active shrinkage protects neurons following axonal transection
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  86. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Organization and morphology of calcitonin gene-related peptide-immunoreactive axons in the whole mouse stomach
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    Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation
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    Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
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  89. Aug 2023
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    Circadian modulation by time-restricted feeding rescues brain pathology and improves memory in mouse models of Alzheimer’s disease
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    Rapid RGR-dependent visual pigment recycling is mediated by the RPE and specialized Müller glia
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    Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types
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    Protocol for deriving proximity, affinity, and stoichiometry of protein interactions using image-based quantitative two-hybrid FRET
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    FUS regulates RAN translation through modulating the G-quadruplex structure of GGGGCC repeat RNA in C9orf72-linked ALS/FTD
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    Cooperative and competitive regulation of the astrocytic transcriptome by neurons and endothelial cells: Impact on astrocyte maturation
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  96. www.embopress.org www.embopress.org
    Embryo-uterine interaction coordinates mouse embryogenesis during implantation
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    The sex-specific role of sensory neuron LKB1 on metabolic stress-induced mechanical hypersensitivity and mitochondrial respiration | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
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  98. Jul 2023
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    Golgi polarity shift instructs dendritic refinement in the neonatal cortex by mediating NMDA receptor signaling
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    Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model
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    Orphan quality control shapes network dynamics and gene expression
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    NeuroMabSeq: high volume acquisition, processing, and curation of hybridoma sequences and their use in generating recombinant monoclonal antibodies and scFvs for neuroscience research
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    Specific prostaglandins are produced in the migratory cells and the surrounding substrate to promote Drosophila border cell migration
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    Multicore fiber optic imaging reveals that astrocyte calcium activity in the cerebral cortex is modulated by internal motivational state
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    A comprehensive atlas of perineuronal net distribution and colocalization with parvalbumin in the adult mouse brain
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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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  108. www.nature.com www.nature.com
    Closed-loop brain stimulation augments fear extinction in male rats
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  109. Jun 2023
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    Nova proteins direct synaptic integration of somatostatin interneurons through activity-dependent alternative splicing
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    Excitatory amino acid transporter 1 supports adult hippocampal neural stem cell self-renewal
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    Transcriptomic landscape of early hair follicle and epidermal development
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions
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  115. rupress.org rupress.org
    Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Noncanonical Activity of Tissue Inhibitor of Metalloproteinases 2 (TIMP2) Improves Cognition and Synapse Density in Aging
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    Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
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    Prolonged dysbiosis and altered immunity under nutritional intervention in a physiological mouse model of severe acute malnutrition
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  119. www.biorxiv.org www.biorxiv.org
    Mapping the Organization and Morphology of Calcitonin Gene-Related Peptide (CGRP)-IR Axons in the Whole Mouse Stomach
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  120. www.jneurosci.org www.jneurosci.org
    Structural modularity tunes mesoscale criticality in biological neuronal networks
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  121. May 2023
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    Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network
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    MFN2-dependent recruitment of ATAT1 coordinates mitochondria motility with α-tubulin acetylation and is disrupted in CMT2A
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  124. www.sciencedirect.com www.sciencedirect.com
    Antagonistic interactions among structured domains in the multivalent Bicc1-ANKS3-ANKS6 protein network govern phase transitioning of target mRNAs
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    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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    Origin of wiring specificity in an olfactory map revealed by neuron type–specific, time-lapse imaging of dendrite targeting
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    Synaptic oligomeric tau in Alzheimer’s disease — A potential culprit in the spread of tau pathology through the brain
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    A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila
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    Aging alters mechanisms underlying voluntary movements in spinal motor neurons of mice, primates, and humans
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    Reinstating olfactory bulb-derived limbic gamma oscillations alleviates depression-like behavioral deficits in rodents
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    Effect of Mitophagy in the Formation of Osteomorphs Derived from Osteoclasts
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    Developmental switch in the function of inhibitory commissural V0d interneurons in zebrafish
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  135. Apr 2023
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deletion of the mRNA stability factor ELAVL1 (HuR) in pancreatic cancer cells disrupts the tumor microenvironment integrity
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    PPRX-1701, a nanoparticle formulation of 6′-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models
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    Ecdysone signaling determines lateral polarity and remodels neurites to form Drosophila’s left-right brain asymmetry
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    γ-Protocadherins control synapse formation and peripheral branching of touch sensory neurons
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    A Novel 3DNA® Nanocarrier effectively delivers payloads to pancreatic tumors
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    Myocardial structure and functional alterations in a preclinical model of exertional heat stroke
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  142. Mar 2023
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    Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage
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    Post-fibrillization nitration of alpha-synuclein abolishes its seeding activity and pathology formation in primary neurons and in vivo
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    Cerebellar nuclei neurons projecting to the lateral parabrachial nucleus modulate classical fear conditioning
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    Ketone bodies promote stroke recovery via GAT-1-dependent cortical network remodeling
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    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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    A Timm-Nissl multiplane microscopic atlas of rat brain zincergic terminal fields and metal-containing glia
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      DOI: 10.1038/s41597-023-02012-6

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    NAADP-Evoked Ca2+ Signaling Leads to Mutant Huntingtin Aggregation and Autophagy Impairment in Murine Astrocytes
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    Proteome of airway surface liquid and mucus in newborn wildtype and cystic fibrosis piglets
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    Cell proliferation and glial cell marker expression in the wall of the third ventricle in the tuberal region of the male mouse hypothalamus during postnatal development
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    Aging and memory are altered by genetically manipulating lactate dehydrogenase in the neurons or glia of flies
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  154. europepmc.org europepmc.org
    ER proteostasis regulators cell-non-autonomously control sleep
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    The P-body protein 4E-T represses translation to regulate the balance between cell genesis and establishment of the postnatal NSC pool
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    Bone marrow Adipoq-lineage progenitors are a major cellular source of M-CSF that dominates bone marrow macrophage development, osteoclastogenesis, and bone mass
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      DOI: 10.7554/eLife.82118

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    Divergent topographic projection of cerebral cortical areas to overlapping cerebellar lobules through distinct regions of the pontine nuclei
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    Organization of projections from the entorhinal cortex to the hippocampal formation of the Egyptian fruit bat Rousettus aegyptiacus
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Smoking-associated Downregulation of FILIP1L Enhances Lung Adenocarcinoma Progression Through Mucin Production, Inflammation, and Fibrosis
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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deconstructing Organs: Single-Cell Analyses, Decellularized Organs, Organoids, and Organ-on-a-Chip Models: A simple method to generate human airway epithelial organoids with externally orientated apical membranes
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    Altered synaptic connectivity in an in vitro human model of STXBP1 encephalopathy
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    The dopamine neuron synaptic map in the striatum
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    CD169+ macrophage intrinsic IL-10 production regulates immune homeostasis during sepsis
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    Developmental neuronal origin regulates neocortical map formation
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  165. www.nature.com www.nature.com
    Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
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    Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors
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    Long-Term SMN- and Ncald-ASO Combinatorial Therapy in SMA Mice and NCALD-ASO Treatment in hiPSC-Derived Motor Neurons Show Protective Effects
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    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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    Intracellular sites of AQP2 S256 phosphorylation identified using inhibitors of the AQP2 recycling itinerary
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    Nail-associated mesenchymal cells contribute to and are essential for dorsal digit tip regeneration
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    En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration
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    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC9672966/
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel function for the sperm adhesion protein IZUMO1 in cell–cell fusion
    1
    1. scibot 19 Nov 2022
      RRID:SCR_013672

      DOI: 10.1083/jcb.202207147

      Resource: ZEN Digital Imaging for Light Microscopy (RRID:SCR_013672)

      Curator: @scibot

      SciCrunch record: RRID:SCR_013672

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      RRID:SCR_013672
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    ncbi.nlm.nih.gov/pmc/articles/PMC9671554/