354 Matching Annotations
  1. May 2026
  2. www.biorxiv.org www.biorxiv.org
    Epilepsy-associated potassium channel KCNT1 is required for multiciliated cell development in Xenopus
    1
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    biorxiv.org/content/10.64898/2026.03.31.710877v1
  3. www.cell.com www.cell.com
    The PAS domain directly regulates hERG channel gating in patch-clamp fluorometry recordings
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    cell.com/biophysj/fulltext/S0006-3495(26)00223-7
  4. Apr 2026
  5. www.biorxiv.org www.biorxiv.org
    Synapse specific alterations of autophagy are a hallmark of Danon disease
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    biorxiv.org/content/10.64898/2026.04.14.718098v1
  6. www.medrxiv.org www.medrxiv.org
    Anillin variant in proteinuric kidney disease drives tubular epithelial cell death, junctional instability, and barrier dysfunction
    1
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    medrxiv.org/content/10.64898/2026.03.24.26348901v1
  7. Mar 2026
  8. dx.doi.org dx.doi.org
    Putative RNA editing of a nicotinic receptor increases acetylcholine sensitivity
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    dx.doi.org/10.1085/jgp.202413677
  9. Feb 2026
  10. www.biorxiv.org www.biorxiv.org
    Supracellular Mechanics and Counter-Rotational Bilateral Flows Orchestrate Posterior Morphogenesis
    1
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    biorxiv.org/content/10.1101/2025.11.18.689090v1
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multiscale and recursive unmixing of spatiotemporal rhythms for live-cell and intravital cardiac microscopy
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC12258837/
  12. journals.plos.org journals.plos.org
    Foxi2 and Sox3 are master transcription regulators that control ectoderm germ layer specification in Xenopus
    1
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    journals.plos.org/plosbiology/article
  13. www.biorxiv.org www.biorxiv.org
    Spinal cord regeneration deploys cell-type specific developmental and non-developmental strategies to restore neuron diversity
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    biorxiv.org/content/10.1101/2025.11.10.687703v1
  14. Jan 2026
  15. journals.plos.org journals.plos.org
    Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms
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    journals.plos.org/plosbiology/article
  16. www.biorxiv.org www.biorxiv.org
    The primary cilium controls programmed cell death via its proteasome-regulating function
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    biorxiv.org/content/10.64898/2026.01.07.698216v1
  17. Oct 2025
  18. app.jove.com app.jove.com
    Optimized Analysis of Proteins from Xenopus Oocytes and Embryos by Immunoblotting
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    app.jove.com/t/69139/optimized-analysis-proteins-from-xenopus-oocytes-embryos
  19. www.biorxiv.org www.biorxiv.org
    Dynamic and non-uniform expression of key transcription factors provides novel insights into the emergence of neural crest cells at the neural plate border
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    biorxiv.org/content/10.1101/2025.10.03.680132v1
  20. www.biorxiv.org www.biorxiv.org
    PAK4 promotes vertex remodeling to maintain epithelial integrity and barrier function
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    biorxiv.org/content/10.1101/2025.10.02.680170v2
  21. www.biorxiv.org www.biorxiv.org
    WDR5 and Myc Cooperate to Regulate Formation of Neural Crest Stem Cells
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    biorxiv.org/content/10.1101/2025.09.19.677424v2
  22. www.biorxiv.org www.biorxiv.org
    Early female germline development in Xenopus laevis: stem cells, nurse cells and germline cysts
    1
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    biorxiv.org/content/10.1101/2025.07.29.667541v1
  23. www.biorxiv.org www.biorxiv.org
    Beyond the Axoneme: Whole-Cell Proteomics Identifies Novel Regulators of Ciliogenesis in Xenopus Epidermal Multiciliated Cells
    1
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    biorxiv.org/content/10.1101/2025.05.20.655211v1
  24. www.biorxiv.org www.biorxiv.org
    Ploidy and neuron size impact nervous system development and function in Xenopus
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    biorxiv.org/content/10.1101/2025.04.22.650131v1
  25. www.nature.com www.nature.com
    Brain implantation of soft bioelectronics via embryonic development
    1
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    nature.com/articles/s41586-025-09106-8
  26. www.sciencedirect.com www.sciencedirect.com
    Differential requirement of Hand1 during differentiation of lateral plate mesoderm lineages in Xenopus laevis
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    sciencedirect.com/science/article/pii/S0012160625001642
  27. www.sciencedirect.com www.sciencedirect.com
    Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord
    1
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    sciencedirect.com/science/article/pii/S0012160625000272
  28. www.sciencedirect.com www.sciencedirect.com
    Optic nerve regeneration in regeneration-capable vertebrates: Lessons from high-throughput genomic studies
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    sciencedirect.com/science/article/pii/B9780443155802000096
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Cell Type-Specific Role for Tubb6 in Ciliogenesis of Xenopus Epidermal Multiciliated Cells
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    onlinelibrary.wiley.com/doi/full/10.1002/cm.70056
  30. Sep 2025
  31. www.biorxiv.org www.biorxiv.org
    Foxh1 is a locus-specific PRC2 recruiter governing germ layer silencing
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    biorxiv.org/content/10.1101/2025.09.21.677640v1
  32. Aug 2025
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PTBP3 Associated With 9q32 Locus Is a Candidate Gene for Nager Syndrome
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    onlinelibrary.wiley.com/doi/10.1002/bdr2.2518
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact
    2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12349098/
  35. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Whole tissue imaging of cellular boundaries at sub-micron resolutions for deep learning cell segmentation: Applications in the analysis of epithelial bending of ectoderm
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    anatomypubs.onlinelibrary.wiley.com/doi/10.1002/dvdy.70061
  36. Jun 2025
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Zmym2 Alters Expression of Key Craniofacial Genes
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    onlinelibrary.wiley.com/doi/10.1002/dvg.70018
  38. May 2025
  39. link.springer.com link.springer.com
    Quantifying Nascent Transcription in Early Embryogenesis
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    link.springer.com/protocol/10.1007/978-1-0716-4522-2_9
  40. www.sciencedirect.com www.sciencedirect.com
    Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis
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    sciencedirect.com/science/article/pii/S1534580725002862
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    An epigenetic clock for Xenopus tropicalis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12098715/
  42. dx.doi.org dx.doi.org
    A homozygous human WNT11 variant is associated with laterality, heart and renal defects
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    dx.doi.org/10.1242/dmm.052211
  43. dx.doi.org dx.doi.org
    RFX6 regulates human intestinal patterning and function upstream of PDX1
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    dx.doi.org/10.1242/dev.202529
  44. www.biorxiv.org www.biorxiv.org
    An epigenetic clock for Xenopus tropicalis reveals age-associated sites enriched in H4K20me3-marked heterochromatin
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    biorxiv.org/content/10.1101/2024.12.21.629929v1
  45. www.biorxiv.org www.biorxiv.org
    A homozygous human WNT11 loss-of-function variant associated with laterality, heart and renal defects
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    biorxiv.org/content/10.1101/2024.11.14.623711v1
  46. www.biorxiv.org www.biorxiv.org
    Koolen-de Vries Syndrome causal gene KANSL1 is required for motile ciliogenesis
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    biorxiv.org/content/10.1101/2024.11.14.621349v1
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The TOG5 domain of CKAP5 is required to interact with F-actin and promote microtubule advancement in neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC11656482/
  48. www.tandfonline.com www.tandfonline.com
    Age-associated DNA methylation changes in Xenopus frogs
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    tandfonline.com/doi/abs/10.1080/15592294.2023.2201517
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Novel laser model of optic nerve transection provides valuable insights about the dynamics of optic nerve regeneration
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11581122/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Krüppel-like factors play essential roles in regulating pluripotency and the formation of neural crest stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12070069/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targets of the transcription factor Six1 identify previously unreported candidate deafness genes
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    pmc.ncbi.nlm.nih.gov/articles/PMC12045605/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SoxB1 transcription factors are essential for initiating and maintaining neural plate border gene expression
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11369808/
  53. www.biorxiv.org www.biorxiv.org
    Spatially ordered zygotic genome activation fulfills embryo quality control
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    biorxiv.org/content/10.1101/2024.12.22.629969v2
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Shh signaling directs dorsal ventral patterning in the regenerating X. tropicalis spinal cord
    1
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    pmc.ncbi.nlm.nih.gov/articles/PMC11507847/
  55. www.biorxiv.org www.biorxiv.org
    Weak magnetic field effects in biology are measurable—accelerated Xenopus embryogenesis in the absence of the geomagnetic field
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    biorxiv.org/content/10.1101/2024.10.10.617626v2
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human rod photoreceptor outer segments are supported by accessory inner segment structures
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    pmc.ncbi.nlm.nih.gov/articles/PMC11326293/
  57. www.biorxiv.org www.biorxiv.org
    Spindle morphology changes between meiosis and mitosis driven by CK2 regulation of the Ran pathway
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    biorxiv.org/content/10.1101/2024.07.25.605073v1
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular basis of urostyle development in frogs: genes and gene regulation underlying an evolutionary novelty
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    pmc.ncbi.nlm.nih.gov/articles/PMC11349433/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Anillin tunes contractility and regulates barrier function during Rho flare–mediated tight junction remodeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC11974952/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The biochemical mechanism of Rho GTPase membrane binding, activation and retention in activity patterning
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    pmc.ncbi.nlm.nih.gov/articles/PMC12048676/
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural basis for saxitoxin congener binding and neutralization by anuran saxiphilins
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    pmc.ncbi.nlm.nih.gov/articles/PMC12022044/
  62. www.sciencedirect.com www.sciencedirect.com
    Leptin signaling promotes blood vessel formation in the Xenopus tail during the embryo-larval transition
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    sciencedirect.com/science/article/pii/S0012160624001106
  63. link.springer.com link.springer.com
    Preparation of Xenopus borealis and Xenopus tropicalis Egg Extracts for Comparative Cell Biology and Evolutionary Studies
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    link.springer.com/protocol/10.1007/978-1-0716-3557-5_11
  64. anatomypubs.onlinelibrary.wiley.com anatomypubs.onlinelibrary.wiley.com
    Interspecific comparisons of anuran embryonic epidermal landscapes and energetic trade-offs in response to changes in salinity
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    anatomypubs.onlinelibrary.wiley.com/doi/full/10.1002/dvdy.70016
  65. Mar 2025
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autism gene variants disrupt enteric neuron migration and cause gastrointestinal dysmotility
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    pmc.ncbi.nlm.nih.gov/articles/PMC11885846/
  67. Jan 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Comparative analysis of Xenopus mesonephric transcriptomics: Conservation of the developmental lineage of nephron stages
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    pmc.ncbi.nlm.nih.gov/articles/PMC11760729/
  69. Dec 2024
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Convergence of autism proteins at the cilium
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    pmc.ncbi.nlm.nih.gov/articles/PMC11643032/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Foxi1 regulates multiple steps of mucociliary development and ionocyte specification through transcriptional and epigenetic mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC11527170/
  72. Sep 2024
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xenopus laevis (Daudin, 1802) as a Model Organism for Bioscience: A Historic Review and Perspective
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    ncbi.nlm.nih.gov/pmc/articles/PMC10295250/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Optimal sparsity allows reliable system-aware restoration of fluorescence microscopy images
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    pmc.ncbi.nlm.nih.gov/articles/PMC10468132/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polyploidy in Xenopus lowers metabolic rate by decreasing total cell surface area
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    ncbi.nlm.nih.gov/pmc/articles/PMC10184464/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transitioning from a research protocol to a scalable applied pathway for Xenopus laevis sperm cryopreservation at a national stock center: The effect of cryoprotectants
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094805/
  77. Aug 2024
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modelling human genetic disorders in Xenopus tropicalis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11179720/
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional multiciliated cell extrusion is controlled by Notch driven basal extrusion and Piezo 1 driven apical extrusion
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    ncbi.nlm.nih.gov/pmc/articles/PMC9882179/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Albino Xenopus laevis tadpoles prefer dark environments compared to wild type
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    ncbi.nlm.nih.gov/pmc/articles/PMC9941856/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Use of Frogs as a Model to Study the Etiology of HLHS
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    ncbi.nlm.nih.gov/pmc/articles/PMC9965361/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monitoring the compaction of single DNA molecules in Xenopus egg extract in real time
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    ncbi.nlm.nih.gov/pmc/articles/PMC10041109/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural interplay of anesthetics and paralytics on muscle nicotinic receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10235084/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Two conserved vocal central pattern generators broadly tuned for fast and slow rates generate species-specific vocalizations in Xenopus clawed frogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10238090/
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Towards the generation of gnotobiotic larvae as a tool to investigate the influence of the microbiome on the development of the amphibian immune system
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    ncbi.nlm.nih.gov/pmc/articles/PMC10258664/
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitotic chromosomes scale to nuclear-cytoplasmic ratio and cell size in Xenopus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10260010/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bidirectional multiciliated cell extrusion is controlled by Notch-driven basal extrusion and Piezo1-driven apical extrusion
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    ncbi.nlm.nih.gov/pmc/articles/PMC10482390/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved chromatin and repetitive patterns reveal slow genome evolution in frogs
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    ncbi.nlm.nih.gov/pmc/articles/PMC10794172/
  89. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Do organisms need an impact factor? Citations of key biological resources including model organisms reveal usage patterns and impact
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    pmc.ncbi.nlm.nih.gov/articles/PMC10827057/
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploring pathways toward open-hardware ecosystems to safeguard genetic resources for biomedical research communities using aquatic model species
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    ncbi.nlm.nih.gov/pmc/articles/PMC11099901/
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na,K-ATPase activity promotes macropinocytosis in colon cancer via Wnt signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11139033/
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET activity plays an essential role in control of stem cell attributes in Xenopus
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    ncbi.nlm.nih.gov/pmc/articles/PMC11266789/
  93. link.springer.com link.springer.com
    DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging
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    link.springer.com/article/10.1007/s11357-023-00840-3
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of an Acute Method to Deliver Transgenes Into the Brains of Adult Xenopus laevis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6213920/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12)
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    ncbi.nlm.nih.gov/pmc/articles/PMC3683776/
  96. www.frontiersin.org www.frontiersin.org
    Quantitative Phenotyping of Xenopus Embryonic Heart Pathophysiology Using Hemoglobin Contrast Subtraction Angiography to Screen Human Cardiomyopathies
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    frontiersin.org/journals/physiology/articles/10.3389/fphys.2019.01197/full
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Importin α partitioning to the plasma membrane regulates intracellular scaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC6368448/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC4549229/
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subfunctionalization of Paralogous Aryl Hydrocarbon Receptors from the Frog Xenopus Laevis: Distinct Target Genes and Differential Responses to Specific Agonists in a Single Cell Type
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    ncbi.nlm.nih.gov/pmc/articles/PMC5291211/
  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DLG5 variants are associated with multiple congenital anomalies including ciliopathy phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785698/
  101. elifesciences.org elifesciences.org
    Co-movement of astral microtubules, organelles and F-actin by dynein and actomyosin forces in frog egg cytoplasm
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    elifesciences.org/articles/60047
  102. www.science.org www.science.org
    Spatial organization of cytokinesis signaling reconstituted in a cell-free system
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  106. Jun 2024
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  114. Feb 2024
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  118. Jan 2024
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  120. Dec 2023
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  129. Aug 2023
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  133. May 2023
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  141. Apr 2023
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  146. Mar 2023
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  166. Nov 2022
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  171. Jul 2022
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  175. Jun 2022
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  178. May 2022
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  187. Apr 2022
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    Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas
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  191. Mar 2022
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    Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains
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  206. Feb 2022
  207. academic.oup.com academic.oup.com
    Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome
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    Evolution of vocal patterns: tuning hindbrain circuits during species divergence
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  209. www.sciencedirect.com www.sciencedirect.com
    Xenopus extract approaches to studying microtubule organization and signaling in cytokinesis
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  210. www.biorxiv.org www.biorxiv.org
    Co-movement of astral microtubules, organelles and F-actin suggests aster positioning by surface forces in frog eggs
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    biorxiv.org/content/10.1101/2020.06.17.154260v1
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    Spatiotemporal Patterning of Zygotic Genome Activation in a Model Vertebrate Embryo
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    The splicing factor PQBP1 regulates mesodermal and neural development through FGF signaling
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    Novel truncating mutations in CTNND1 cause a dominant craniofacial and cardiac syndrome
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  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xenopus pax6 mutants affect eye development and other organ systems, and have phenotypic similarities to human aniridia patients
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  215. www.biorxiv.org www.biorxiv.org
    Cell-Cell Adhesion During Nephron Development Is Driven by Wnt/PCP Formin Daam1
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    biorxiv.org/content/10.1101/2020.08.18.256123v1
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    Xenopus mutant reveals necessity of rax for specifying the eye field which otherwise forms tissue with telencephalic and diencephalic character
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    The Wnt/PCP formin Daam1 drives cell-cell adhesion during nephron development
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    Genome-wide transcriptomics analysis identifies sox7 and sox18 as specifically regulated by gata4 in cardiomyogenesis
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    Disassembly of Actin and Keratin Networks by Aurora B Kinase at the Midplane of Cleaving Xenopus laevis Eggs
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    Using supported bilayers to study the spatiotemporal organization of membrane-bound proteins
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    Model systems for regeneration: Xenopus
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  222. www.pnas.org www.pnas.org
    SPARC triggers a cell-autonomous program of synapse elimination
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  223. journals.sagepub.com journals.sagepub.com
    The Xenopus tadpole: An in vivo model to screen drugs favoring remyelination - Abdelkrim Mannioui, Quentin Vauzanges, Jean Baptiste Fini, Esther Henriet, Somya Sekizar, Loris Azoyan, Jean Léon Thomas, David Du Pasquier, Carine Giovannangeli, Barbara Demeneix, Catherine Lubetzki, Bernard Zalc, 2018
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  224. symposium.cshlp.org symposium.cshlp.org
    Spindle-to-Cortex Communication in Cleaving Frog Eggs
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    Microtubule Growth Rates Are Sensitive to Global and Local Changes in Microtubule Plus-End Density
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    Centriole Number and the Accumulation of Microtubules Modulate the Timing of Apical Insertion during Radial Intercalation
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    no privacy, a Xenopus tropicalis mutant, is a model of human Hermansky-Pudlak Syndrome and allows visualization of internal organogenesis during tadpole development
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