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    Microcephaly-causative ASPM mutations disrupt mitotic spindle orientation and timely specification of human outer radial glia cells
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  3. Oct 2026
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    Opposing functions of gut immunomodulatory metabolites on CAR-T therapy
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  5. Sep 2026
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    Engineering a Model Cell for Rational Tuning of GPCR Signaling
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  7. Jul 2026
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  11. May 2026
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    CD70 regulates the NF1/Ras/ERK axis to promote metastatic potential in clear cell renal cell carcinoma
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  13. Apr 2026
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    E-cadherin expression promotes tumor growth via KLRG1-dependent pathways
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    Actomyosin contractility is a potent suppressor of mesoderm induction by human pluripotent stem cells
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    Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs
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    MAPK Pathway Mutations Emerge in Mutant IDH1 Inhibitor–Resistant Cholangiocarcinoma and Attenuate the IFN Response
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    Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia
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    A dual-reporter mouse for therapeutic discovery in Angelman syndrome
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  20. Nov 2025
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    HMMR has oncoprotein-like properties in neuroblastoma cells and high HMMR expression has independent prognostic potential in neuroblastomas
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  22. Sep 2025
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    Ultrabright chemical labeling enables rapid neural connectivity profiling in large tissue samples
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  24. Aug 2025
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    USP15: the fourth Proteasome-associated DUB
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  26. Jul 2025
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    Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability
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    Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening
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  30. Jun 2025
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage
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  34. Apr 2025
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    Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants
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  36. Mar 2025
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    Opposing roles for Bmp signalling during the development of electrosensory lateral line organs
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  38. Feb 2025
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    Biosensor characterization: formal methods from the perspective of proteome fractions
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    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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  41. Dec 2024
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    High-throughput optimisation of protein secretion in yeast via an engineered biosensor
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  43. Nov 2024
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    TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
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  45. Jul 2024
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    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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  48. Jun 2024
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    CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons
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  50. May 2024
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    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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  54. Mar 2024
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    Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa
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    Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
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  57. Feb 2024
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    Dose-Response Profiling in Heterologous Gene Expression: Insights from Proteome Fraction Analysis
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    Parkinson’s Disease Risk Enhancers in Microglia
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  60. Dec 2023
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    Intron Editing Reveals SNORD-Dependent Maturation of the Small Nucleolar RNA Host Gene GAS5 in Human Cells
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    Glucose stress causes mRNA retention in nuclear Nab2 condensates
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    Optogenetic manipulation of BMP signaling to drive chondrogenic differentiation of hPSCs
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  64. Nov 2023
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    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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  67. Aug 2023
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    The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
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    Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus
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  70. Jul 2023
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    Base editing enables duplex point mutagenesis in Clostridium autoethanogenum at the price of numerous off-target mutations
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  72. Jun 2023
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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  74. May 2023
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    Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling
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  76. Nov 2022
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    TEMPO enables sequential genetic labeling and manipulation of vertebrate cell lineages
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  80. Sep 2022
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    Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning
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  82. Aug 2022
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    Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells
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  84. Apr 2022
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    Colorectal cancer is associated with the presence of cancer driver mutations in normal colon
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  86. Aug 2021
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  89. Jul 2021
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    Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival
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  92. Jun 2021
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    Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs
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  94. May 2021
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    Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision
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  96. Mar 2021
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    An optimized CRISPR/Cas9 approach for precise genome editing in neurons
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  98. Sep 2020
  99. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication
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    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
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    Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy
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  103. Jan 2020
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Are Small Nucleolar RNAs “CRISPRable”? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells
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    Unlimited Genetic Switches for Cell-Type-Specific Manipulation
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    Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
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    Bioprospecting Plant Growth-Promoting Rhizobacteria That Mitigate Drought Stress in Grasses
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  110. Nov 2018
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    Immunomimetic Designer Cells Protect Mice from MRSA Infection
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    The Epstein-Barr Virus Regulome in Lymphoblastoid Cells
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    Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin
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  114. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
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  115. Nov 2017
  116. www.cell.com www.cell.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
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  117. bioinformatics.oxfordjournals.org bioinformatics.oxfordjournals.org
    CRISPR-DO for genome-wide CRISPR design and optimization
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