72 Matching Annotations
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    E-cadherin expression promotes tumor growth via KLRG1-dependent pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108842/
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    Actomyosin contractility is a potent suppressor of mesoderm induction by human pluripotent stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13108843/
  4. Apr 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13069148/
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    MAPK Pathway Mutations Emerge in Mutant IDH1 Inhibitor–Resistant Cholangiocarcinoma and Attenuate the IFN Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13056288/
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    Single-Cell Lineage Tracing Uncovers Resistance Signatures and Sensitizing Strategies to FLT3 Inhibitors in Acute Myeloid Leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618455/
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    A dual-reporter mouse for therapeutic discovery in Angelman syndrome
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    pmc.ncbi.nlm.nih.gov/articles/PMC13041673/
  9. Nov 2025
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    HMMR has oncoprotein-like properties in neuroblastoma cells and high HMMR expression has independent prognostic potential in neuroblastomas
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    nature.com/articles/s41598-025-23141-5
  11. Sep 2025
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    Ultrabright chemical labeling enables rapid neural connectivity profiling in large tissue samples
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    sciencedirect.com/science/article/pii/S0896627325006579
  13. Aug 2025
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    USP15: the fourth Proteasome-associated DUB
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    biorxiv.org/content/10.1101/2025.08.13.670075v1
  15. Jul 2025
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    Differential roles of NaV1.2 and NaV1.6 in neocortical pyramidal cell excitability
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    elifesciences.org/articles/105696
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    Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
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    sciencedirect.com/science/article/pii/S0092867425006919
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    Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
  19. Jun 2025
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    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    sciencedirect.com/science/article/pii/S2211124725006928
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    Lentiviral CRISPRa/i in the adult prairie vole brain: modulating neuronal gene expression without DNA cleavage
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    pmc.ncbi.nlm.nih.gov/articles/PMC12162470/
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  23. Apr 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision genome editing and in-cell measurements of oxidative DNA damage repair enable functional and mechanistic characterization of cancer-associated MUTYH variants
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    pmc.ncbi.nlm.nih.gov/articles/PMC11952967/
  25. Mar 2025
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Opposing roles for Bmp signalling during the development of electrosensory lateral line organs
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    pmc.ncbi.nlm.nih.gov/articles/PMC11936418/
  27. Feb 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Biosensor characterization: formal methods from the perspective of proteome fractions
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  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
  30. Dec 2024
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    High-throughput optimisation of protein secretion in yeast via an engineered biosensor
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  32. Nov 2024
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    TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
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    biorxiv.org/lookup/doi/10.1101/2024.10.29.620655
  34. Jul 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
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    The SASP factor IL-6 sustains cell-autonomous senescent cells via a cGAS-STING-NFκB intracrine senescent noncanonical pathway
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    onlinelibrary.wiley.com/doi/10.1111/acel.14258
  37. Jun 2024
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    CGG repeats in the human FMR1 gene regulate mRNA localization and cellular stress in developing neurons
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    sciencedirect.com/science/article/pii/S2211124724006582
  39. May 2024
  40. www.biorxiv.org www.biorxiv.org
    SMAD4 and KRAS status shape malignant-stromal crosstalk in pancreatic cancer
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    biorxiv.org/content/10.1101/2024.04.28.591518v1
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    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
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  43. Mar 2024
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Regulation of astrocyte metabolism by mitochondrial translocator protein 18 kDa
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16089
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    Engraftment of adult hematopoietic stem and progenitor cells in a novel model of humanized mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10904995/
  46. Feb 2024
  47. www.biorxiv.org www.biorxiv.org
    Dose-Response Profiling in Heterologous Gene Expression: Insights from Proteome Fraction Analysis
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    biorxiv.org/content/10.1101/2023.12.01.569588v1
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    Parkinson’s Disease Risk Enhancers in Microglia
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    ncbi.nlm.nih.gov/pmc/articles/PMC10845915/
  49. Dec 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intron Editing Reveals SNORD-Dependent Maturation of the Small Nucleolar RNA Host Gene GAS5 in Human Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC10743478/
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    Glucose stress causes mRNA retention in nuclear Nab2 condensates
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    Optogenetic manipulation of BMP signaling to drive chondrogenic differentiation of hPSCs
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    sciencedirect.com/science/article/pii/S2211124723015140
  53. Nov 2023
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    CRISPR-Cas12a-integrated transgenes in genomic safe harbors retain high expression in human hematopoietic iPSC-derived lineages and primary cells
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    sciencedirect.com/science/article/pii/S2589004223023647
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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    biorxiv.org/content/10.1101/2023.10.24.563645v1
  56. Aug 2023
  57. www.sciencedirect.com www.sciencedirect.com
    The Achromobacter type 3 secretion system drives pyroptosis and immunopathology via independent activation of NLRC4 and NLRP3 inflammasomes
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    sciencedirect.com/science/article/pii/S2211124723010239
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    Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus
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    ncbi.nlm.nih.gov/pmc/articles/PMC10404257/
  59. Jul 2023
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Base editing enables duplex point mutagenesis in Clostridium autoethanogenum at the price of numerous off-target mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10366002/
  61. Jun 2023
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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    sciencedirect.com/science/article/pii/S2211124723005442
  63. May 2023
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    Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling
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  65. Nov 2022
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    De-erosion of X chromosome dosage compensation by the editing of XIST regulatory regions restores the differentiation potential in hPSCs
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    sciencedirect.com/science/article/pii/S2667237522002491
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    TEMPO enables sequential genetic labeling and manipulation of vertebrate cell lineages
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    sciencedirect.com/science/article/pii/S0896627322009953
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9-induced gene knockout in zebrafish
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    ncbi.nlm.nih.gov/pmc/articles/PMC9617198/
  69. Sep 2022
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    Functionally distinct NPAS4-expressing somatostatin interneuron ensembles critical for motor skill learning
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  71. Aug 2022
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    Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells
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    sciencedirect.com/science/article/pii/S0301468122000627
  73. Apr 2022
  74. aacrjournals.org aacrjournals.org
    Colorectal cancer is associated with the presence of cancer driver mutations in normal colon
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    aacrjournals.org/cancerres/article/82/8/1492/694359/Colorectal-Cancer-Is-Associated-with-the-Presence
  75. Aug 2021
  76. academic.oup.com academic.oup.com
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  78. Jul 2021
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC6611694/
  81. Jun 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Deletion of lncRNA XACT does not change expression dosage of X-linked genes, but affects differentiation potential in hPSCs
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    sciencedirect.com/science/article/pii/S2211124721005738
  83. May 2021
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-photopic and photopic visual cycles differentially regulate immediate, early, and late phases of cone photoreceptor-mediated vision
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    ncbi.nlm.nih.gov/pmc/articles/PMC7212626/
  85. Mar 2021
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An optimized CRISPR/Cas9 approach for precise genome editing in neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC7946428/
  87. Sep 2020
  88. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication
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    pubmed.ncbi.nlm.nih.gov/32966791/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC7244321/
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    Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
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    sciencedirect.com/science/article/pii/S2352396420301614
  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC6984822/
  92. Jan 2020
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Are Small Nucleolar RNAs “CRISPRable”? A Report on Box C/D Small Nucleolar RNA Editing in Human Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6856654/
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    Unlimited Genetic Switches for Cell-Type-Specific Manipulation
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research
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    ncbi.nlm.nih.gov/pmc/articles/PMC6579517/
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    Bioprospecting Plant Growth-Promoting Rhizobacteria That Mitigate Drought Stress in Grasses
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    frontiersin.org/article/10.3389/fmicb.2019.02106/full
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  99. Nov 2018
  100. www.sciencedirect.com www.sciencedirect.com
    Immunomimetic Designer Cells Protect Mice from MRSA Infection
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    sciencedirect.com/science/article/pii/S0092867418306512
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    The Epstein-Barr Virus Regulome in Lymphoblastoid Cells
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    sciencedirect.com/science/article/pii/S1931312817303554
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    Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin
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    sciencedirect.com/science/article/pii/S1097276518302235
  103. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC5924568/
  104. Nov 2017
  105. www.cell.com www.cell.com
    Interspecies Chimerism with Mammalian Pluripotent Stem Cells
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  106. bioinformatics.oxfordjournals.org bioinformatics.oxfordjournals.org
    CRISPR-DO for genome-wide CRISPR design and optimization
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    bioinformatics.oxfordjournals.org/content/early/2016/07/31/bioinformatics.btw476.long