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  1. Last 7 days
  2. elifesciences.org elifesciences.org
    Control of 3′ splice site selection by the yeast splicing factor Fyv6
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    1. scibot 20 Dec 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.100449

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    elifesciences.org/articles/100449
  3. 52.53.155.43 52.53.155.43
    can-24-2450-html.html
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    1. scibot 19 Dec 2024
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      DOI: 10.1158/0008-5472.can-24-2450

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    52.53.155.43/eda542f05a259fcd2586bec9365306e8eda4954b/can-24-2450-html.html
  4. Dec 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies
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    1. scibot 13 Dec 2024
      RRID:SCR_014222

      DOI: 10.1111/jnc.16274

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16274
  6. www.sciencedirect.com www.sciencedirect.com
    Dual BACH1 regulation by complementary SCF-type E3 ligases
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    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.006

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    sciencedirect.com/science/article/pii/S0092867424013229
  7. 52.53.155.43 52.53.155.43
    quinodoz-et-al-2024-de-novo-variants-in-lrrc8c-resulting-in-constitutive-channel-activation-cause-a-human-multisystem-html.html
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    1. scibot 06 Dec 2024
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      DOI: 10.1038/s44318-024-00322-y

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    52.53.155.43/3ab1f2ac64d4a9d1e1b8c8801c1d180b19e6523a/quinodoz-et-al-2024-de-novo-variants-in-lrrc8c-resulting-in-constitutive-channel-activation-cause-a-human-multisystem-html.html
  8. www.sciencedirect.com www.sciencedirect.com
    Reactive oxygen species control protein degradation at the mitochondrial import gate
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    1. scibot 06 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.004

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    sciencedirect.com/science/article/pii/S1097276524009092
  9. Nov 2024
  10. www.embopress.org www.embopress.org
    Structure of a step II catalytically activated spliceosome from Chlamydomonas reinhardtii
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    1. scibot 28 Nov 2024
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      DOI: 10.1038/s44318-024-00274-3

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    embopress.org/doi/10.1038/s44318-024-00274-3
  11. www.biorxiv.org www.biorxiv.org
    Inhibition of Parkinson’s Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
    1
    1. scibot 26 Nov 2024
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      DOI: 10.1101/2023.09.07.556689

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    biorxiv.org/content/10.1101/2023.09.07.556689v1
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cryo‐EM reveals transition states of the Acinetobacter baumannii F1 ‐ATPase rotary subunits γ and ε, unveiling novel compound targets
    1
    1. scibot 26 Nov 2024
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      DOI: 10.1096/fj.202401629R

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    pmc.ncbi.nlm.nih.gov/articles/PMC11580714/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Structural insights into human zinc transporter ZnT1 mediated Zn2+ efflux
    1
    1. scibot 14 Nov 2024
      RRID:SCR_014222

      DOI: 10.1038/s44319-024-00287-3

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    pmc.ncbi.nlm.nih.gov/articles/PMC11549101/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional implications of the exon 9 splice insert in GluK1 kainate receptors
    1
    1. scibot 10 Nov 2024
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      DOI: 10.7554/eLife.89755

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540303/
  15. elifesciences.org elifesciences.org
    TRPML1 gating modulation by allosteric mutations and lipids
    1
    1. scibot 07 Nov 2024
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      DOI: 10.7554/eLife.100987

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    elifesciences.org/articles/100987
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
    1
    1. scibot 07 Nov 2024
      RRID:SCR_014222

      DOI: 10.1158/1535-7163.MCT-23-0487

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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  17. Oct 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED
    1
    1. scibot 04 Oct 2024
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      DOI: 10.1016/j.molcel.2024.09.002

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    sciencedirect.com/science/article/pii/S1097276524007354
  19. Sep 2024
  20. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
    1
    1. scibot 28 Sep 2024
      RRID:SCR_014222

      DOI: 10.1101/2024.09.17.613365

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    biorxiv.org/content/10.1101/2024.09.17.613365v1
  21. www.sciencedirect.com www.sciencedirect.com
    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
    1
    1. scibot 27 Sep 2024
      RRID:SCR_01422

      DOI: 10.1016/j.str.2024.08.022

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    sciencedirect.com/science/article/pii/S0969212624003691
  22. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  23. Aug 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)
    1
    1. scibot 30 Aug 2024
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      DOI: 10.7554/eLife.93510

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    ncbi.nlm.nih.gov/pmc/articles/PMC11357348/
  25. www.cell.com www.cell.com
    Structural insights into the chloroplast protein import in land plants
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.cell.2024.08.003

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    cell.com/cell/fulltext/S0092-8674(24)00894-8
  26. www.sciencedirect.com www.sciencedirect.com
    Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.cell.2024.08.002

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    sciencedirect.com/science/article/pii/S0092867424008936
  27. www.sciencedirect.com www.sciencedirect.com
    Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
    1
    1. scibot 18 Aug 2024
      RRID:SCR_014222

      DOI: 10.1016/j.xcrm.2024.101668

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    sciencedirect.com/science/article/pii/S2666379124003823
  28. europepmc.orghttp europepmc.orghttp
    Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes
    1
    1. scibot 02 Aug 2024
      COOT

      DOI: 10.1016/j.cell.2017.09.008

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    europepmc.orghttp//europepmc.org/articles/PMC5651216/
  29. www.proquest.com www.proquest.com
    Mechanism of Ca2+ transport by ferroportin - ProQuest
    1
    1. scibot 02 Aug 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.82947

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    proquest.com/docview/2771288630
  30. Jul 2024
  31. www.sciencedirect.com www.sciencedirect.com
    Structure of the Hir histone chaperone complex
    1
    1. scibot 24 Jul 2024
      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2024.05.031

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    sciencedirect.com/science/article/pii/S1097276524004787
  32. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
    1
    1. scibot 19 Jul 2024
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      DOI: 10.1016/j.molcel.2024.06.006

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    sciencedirect.com/science/article/pii/S1097276524004842
  33. www.sciencedirect.com www.sciencedirect.com
    Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38
    1
    1. scibot 16 Jul 2024
      RRID:SCR_01422

      DOI: 10.1016/j.celrep.2024.114502

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    sciencedirect.com/science/article/pii/S2211124724008313
  34. Jun 2024
  35. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014222

      DOI: 10.1016/j.jbc.2024.107469

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    sciencedirect.com/science/article/pii/S0021925824019707
  36. www.cell.com www.cell.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
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    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.str.2024.05.013

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    cell.com/structure/fulltext/S0969-2126(24)00190-4
  37. www.cell.com www.cell.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
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    1. scibot 05 Jun 2024
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      DOI: 10.1016/j.cell.2024.05.002

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    cell.com/cell/fulltext/S0092-8674(24)00493-8
  38. www.sciencedirect.com www.sciencedirect.com
    Cryo-electron tomography reveals the packaging pattern of RuBisCOs in Synechococcus β-carboxysome
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    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.str.2024.05.007

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    sciencedirect.com/science/article/pii/S0969212624001849
  39. May 2024
  40. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
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    1. scibot 31 May 2024
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      DOI: 10.1016/j.celrep.2024.114259

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    sciencedirect.com/science/article/pii/S2211124724005874
  41. Apr 2024
  42. www.sciencedirect.com www.sciencedirect.com
    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
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      DOI: 10.1016/j.immuni.2024.03.022

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    sciencedirect.com/science/article/pii/S1074761324001432
  43. www.nature.com www.nature.com
    Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
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      DOI: 10.1038/s41594-024-01268-9

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    nature.com/articles/s41594-024-01268-9
  44. www.sciencedirect.com www.sciencedirect.com
    Staphylococcus aureus skin colonization is mediated by SasG lectin variation
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    sciencedirect.com/science/article/pii/S2211124724003504
  45. www.cell.com www.cell.com
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
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      DOI: 10.1016/j.celrep.2024.114035

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    cell.com/cell-reports/fulltext/S2211-1247(24)00363-2
  46. Mar 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
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      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  48. www.sciencedirect.com www.sciencedirect.com
    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
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      DOI: 10.1016/j.immuni.2024.03.001

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    sciencedirect.com/science/article/pii/S1074761324000979
  49. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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      DOI: 10.1016/j.cell.2024.02.013

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      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  50. www.sciencedirect.com www.sciencedirect.com
    Epstein-Barr virus gp42 antibodies reveal sites of vulnerability for receptor binding and fusion to B cells
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      DOI: 10.1016/j.immuni.2024.02.008

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    sciencedirect.com/science/article/pii/S1074761324000840
  51. www.sciencedirect.com www.sciencedirect.com
    Structure of the plant plastid-encoded RNA polymerase
    2
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      DOI: 10.1016/j.cell.2024.01.036

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      DOI: 10.1016/j.cell.2024.01.036

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    sciencedirect.com/science/article/pii/S009286742400103X
  52. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
    1
    1. scibot 01 Mar 2024
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2024.01.026

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  53. Feb 2024
  54. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
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      RRID:SCR_014222

      DOI: 10.1158/1535-7163.MCT-22-0681

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  55. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
      RRID:SCR_014222

      DOI: 10.7554/eLife.39611

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  56. Jan 2024
  57. www.sciencedirect.com www.sciencedirect.com
    Structural evidence for protein-protein interaction between the non-canonical methyl-CpG-binding domain of SETDB proteins and C11orf46
    1
    1. scibot 11 Jan 2024
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      DOI: 10.1016/j.str.2023.12.001

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    sciencedirect.com/science/article/pii/S0969212623004434
  58. Dec 2023
  59. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    1. scibot 20 Dec 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.113516

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  60. www.sciencedirect.com www.sciencedirect.com
    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
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  61. www.sciencedirect.com www.sciencedirect.com
    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
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  62. www.sciencedirect.com www.sciencedirect.com
    Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants
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      RRID:SCR_014222

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  63. Nov 2023
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts
    1
    1. scibot 18 Nov 2023
      RRID:SCR_01422

      DOI: 10.1158/2159-8290.CD-23-0396

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  65. www.cell.com www.cell.com
    Architecture of the bacteriophage lambda tail
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    cell.com/structure/fulltext/S0969-2126(23)00363-5
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
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      DOI: 10.7554/eLife.87167

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  67. Oct 2023
  68. www.sciencedirect.com www.sciencedirect.com
    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    1. scibot 28 Oct 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.113321

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  69. www.sciencedirect.com www.sciencedirect.com
    Concerted structural rearrangements enable RNA channeling into the cytoplasmic Ski238-Ski7-exosome assembly
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      RRID:SCR_014222coot

      DOI: 10.1016/j.molcel.2023.09.037

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  70. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
    2
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      RRID:SCR_014222

      DOI: 10.1038/s41556-023-01248-z

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  71. 52.53.155.43 52.53.155.43
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      RRID:SCR_014222

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  72. Sep 2023
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
    1
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      RRID:SCR_014222

      DOI: 10.1158/2159-8290.CD-23-0475

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  74. Aug 2023
  75. 52.53.155.43 52.53.155.43
    Phage T3 overcomes the BREX defense through SAM cleavage and inhibition of SAM synthesis by SAM lyase
    2
    1. scibot 18 Aug 2023
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112972

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  76. 52.53.155.43 52.53.155.43
    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
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      RRID:SCR_014222

      DOI: 10.1016/j.isci.2023.107579

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  77. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
    2
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112926

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  78. Jul 2023
  79. www.sciencedirect.com www.sciencedirect.com
    Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy
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      DOI: 10.1016/j.cell.2023.06.020

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    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112827

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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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      RRID:SCR_014222

      DOI: 10.7554/eLife.86029

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  82. 52.53.155.43 52.53.155.43
    cd-23-0475-html.html
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      RRID:SCR_014222

      DOI: 10.1158/2159-8290.cd-23-0475

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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
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      DOI: 10.7554/eLife.87178

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  84. Jun 2023
  85. www.sciencedirect.com www.sciencedirect.com
    A structural blueprint for interleukin-21 signal modulation
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      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2023.112657

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  86. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
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      DOI: 10.1016/j.molcel.2023.05.036

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    Centromere/kinetochore is assembled through CENP-C oligomerization
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      RRID:SCR_014222

      DOI: 10.1016/j.molcel.2023.05.023

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    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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      DOI: 10.1016/j.chembiol.2023.05.007

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    sciencedirect.com/science/article/pii/S2451945623001502
  89. May 2023
  90. 52.53.155.43 52.53.155.43
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
    1
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      RRID:S CR_01 4222

      DOI: 10.1101/2023.03.06.531323

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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter
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      DOI: 10.7554/eLife.84006

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  92. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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  93. Apr 2023
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the endothelin-1-ETB-Gi complex
    1
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      RRID:SCR_014222

      DOI: 10.7554/eLife.85821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10129325/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of a plant NRAMP-related aluminum transporter
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      DOI: 10.7554/eLife.85641

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115441/
  96. www.sciencedirect.com www.sciencedirect.com
    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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      RRID:SCR_014222

      DOI: 10.1016/j.immuni.2023.03.009

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  97. Mar 2023
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Cancer Antigen Mesothelin and Its Complexes with Therapeutic Antibodies
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      RRID:SCR_014222

      DOI: 10.1158/2767-9764.CRC-22-0306

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    Immunodominant surface epitopes power immune evasion in the African trypanosome
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      DOI: 10.1016/j.celrep.2023.112262

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of NF-κB p52 homodimer-DNA complexes rationalize binding mechanisms and transcription activation
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      DOI: 10.7554/eLife.86258

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    ncbi.nlm.nih.gov/pmc/articles/PMC9991059/
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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      RRID:SCR_014222

      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  102. Feb 2023
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
    1
    1. scibot 17 Feb 2023
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      DOI: 10.1126/sciadv.adg2997

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  104. www.sciencedirect.com www.sciencedirect.com
    Structural basis of a transcription pre-initiation complex on a divergent promoter
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of Ca2+ transport by ferroportin
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  106. Jan 2023
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    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
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    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
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  109. Dec 2022
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    Structures of drug-specific monoclonal antibodies bound to opioids and nicotine reveal a common mode of binding
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of human phagocyte NADPH oxidase in the resting state
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  112. Nov 2022
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    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  117. Oct 2022
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    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
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  119. Sep 2022
  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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  121. Aug 2022
  122. www.sciencedirect.com www.sciencedirect.com
    TITLE: Engineering SARS-CoV-2 neutralizing antibodies for increased potency and reduced viral escape pathways
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    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Emergence of immune escape at dominant SARS-CoV-2 killer T-cell epitope
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  125. Jul 2022
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    Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
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  127. Jun 2022
  128. www.cell.com www.cell.com
    Rational exploration of fold atlas for human solute carrier proteins
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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  130. May 2022
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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  132. Apr 2022
  133. www.sciencedirect.com www.sciencedirect.com
    Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
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    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
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  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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  137. elifesciences.org elifesciences.org
    Assembly of recombinant tau into filaments identical to those of Alzheimer’s disease and chronic traumatic encephalopathy
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  138. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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  139. Mar 2022
  140. www.sciencedirect.com www.sciencedirect.com
    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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    Phosphosite-dependent Presentation of Dual Phosphorylated Peptides by MHC Class I Molecules
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of nanobodies neutralizing SARS-CoV-2 variants
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    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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    Structure and ion-release mechanism of PIB-4-type ATPases
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    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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  149. Feb 2022
  150. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti
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    Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
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    The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
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    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
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  154. elifesciences.org elifesciences.org
    Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
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  155. Jan 2022
  156. elifesciences.org elifesciences.org
    Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
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  157. www.cell.com www.cell.com
    Structural basis of bacteriophage lambda capsid maturation
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      DOI: 10.1016/j.str.2021.12.009

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  158. www.sciencedirect.com www.sciencedirect.com
    Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II
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  160. Dec 2021
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    Rational engineering enables co-crystallization and structural determination of the HIV-1 matrix-tRNA complex
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  162. Nov 2021
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    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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  164. Oct 2021
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  166. www.cell.com www.cell.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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  171. Sep 2021
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    Structural basis for membrane recruitment of ATG16L1 by WIPI2 in autophagy
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    A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease
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    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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    Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace
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    A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites
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    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
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  182. Aug 2021
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    TMEM120A is a coenzyme A-binding membrane protein with structural similarities to ELOVL fatty acid elongase
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    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    HIV-1 matrix-tRNA complex structure reveals basis for host control of Gag localization
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    Protocol for the use of focused ion-beam milling to prepare crystalline lamellae for microcrystal electron diffraction (MicroED)
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  188. pubs.acs.org pubs.acs.org
    Structural, Biochemical, and Evolutionary Characterizations of Glyoxylate/Hydroxypyruvate Reductases Show Their Division into Two Distinct Subfamilies
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    Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies
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    Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
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    Structure and analysis of nanobody binding to the human ASIC1a ion channel
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    Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling
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    Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase
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    sciencedirect.com/science/article/pii/S1097276518309845
  204. Jul 2021
  205. www.sciencedirect.com www.sciencedirect.com
    Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
    1
    1. scibot 31 Jul 2021
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2018.05.041

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    sciencedirect.com/science/article/pii/S0092867418306536
  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
    2
    1. scibot 31 Jul 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.40444

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      RRID:SCR_014222
    2. scibot 28 Jul 2021
      RRID: SCR_014222

      DOI: 10.7554/eLife.40444

      Resource: Coot (RRID:SCR_014222)

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      RRID:SCR_014222 RRIDCUR:Unrecognized
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    ncbi.nlm.nih.gov/pmc/articles/PMC6231770/
  207. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms
    1
    1. scibot 31 Jul 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.43075

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      RRID:SCR_014222 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6365055/
  208. elifesciences.org elifesciences.org
    Cryo-EM analyses reveal the common mechanism and diversification in the activation of RET by different ligands
    1
    1. scibot 30 Jul 2021
      Coot

      DOI: 10.7554/eLife.47650

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      RRID:SCR_014222 RRIDCUR:Missing
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    elifesciences.org/articles/47650
  209. www.nature.com www.nature.com
    Regulation of the endosomal SNX27-retromer by OTULIN
    1
    1. scibot 30 Jul 2021
      COOT

      DOI: 10.1038/s41467-019-12309-z

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      RRID:SCR_014222 RRIDCUR:Missing
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    nature.com/articles/s41467-019-12309-z
  210. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.7554/eLife.46417

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    elifesciences.org/articles/46417
  211. www.pnas.org www.pnas.org
    Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
    1
    1. scibot 29 Jul 2021
      Coot

      DOI: 10.1073/pnas.1906253116

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    pnas.org/content/116/31/15505
  212. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Molecular docking predictions of fragrance binding to human leukocyte antigen molecules
    1
    1. scibot 29 Jul 2021
      coot

      DOI: 10.1111/cod.13283

      Resource: Coot (RRID:SCR_014222)

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    onlinelibrary.wiley.com/doi/full/10.1111/cod.13283
  213. www.sciencedirect.com www.sciencedirect.com
    STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.1016/j.cell.2019.05.036

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    sciencedirect.com/science/article/pii/S0092867419305641
  214. www.sciencedirect.com www.sciencedirect.com
    Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.1016/j.chembiol.2019.05.010

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    sciencedirect.com/science/article/pii/S2451945619301795
  215. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of CD160:HVEM Recognition
    1
    1. scibot 29 Jul 2021
      COOT

      DOI: 10.1016/j.str.2019.05.010

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S0969212619301728
  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of translationally inactive mammalian ribosomes
    1
    1. scibot 28 Jul 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.40486

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    ncbi.nlm.nih.gov/pmc/articles/PMC6226290/
  217. www.sciencedirect.com www.sciencedirect.com
    Characterization of MCU-Binding Proteins MCUR1 and CCDC90B — Representatives of a Protein Family Conserved in Prokaryotes and Eukaryotic Organelles
    1
    1. scibot 28 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.11.004

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S0969212618304234
  218. www.sciencedirect.com www.sciencedirect.com
    Homer Tetramer Promotes Actin Bundling Activity of Drebrin
    1
    1. scibot 28 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.10.011

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S0969212618303721
  219. www.sciencedirect.com www.sciencedirect.com
    Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor
    1
    1. scibot 28 Jul 2021
      COOT

      DOI: 10.1016/j.cell.2018.10.043

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S0092867418313990
  220. www.sciencedirect.com www.sciencedirect.com
    Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection
    1
    1. scibot 28 Jul 2021
      RRID:SCR_014222

      DOI: 10.1016/j.celrep.2019.11.106

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    sciencedirect.com/science/article/pii/S2211124719316298
  221. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases
    1
    1. scibot 28 Jul 2021
      SCR_014222

      DOI: 10.7554/eLife.26111

      Resource: Coot (RRID:SCR_014222)

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    ncbi.nlm.nih.gov/pmc/articles/PMC5468089/
  222. www.sciencedirect.com www.sciencedirect.com
    Structure of a Complete Mediator-RNA Polymerase II Pre-Initiation Complex
    2
    1. scibot 27 Jul 2021
      SCR_014222

      DOI: 10.1016/j.cell.2016.08.050

      Resource: Coot (RRID:SCR_014222)

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      RRIDCUR:Unrecognized RRID:SCR_014222
    2. scibot 27 Jul 2021
      SCR_014222

      DOI: 10.1016/j.cell.2016.08.050

      Resource: Coot (RRID:SCR_014222)

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      RRIDCUR:Validated RRID:SCR_014222
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    sciencedirect.com/science/article/pii/S0092867416311473
  223. www.sciencedirect.com www.sciencedirect.com
    Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.str.2018.10.007

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S096921261830368X
  224. www.sciencedirect.com www.sciencedirect.com
    Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.neuron.2018.10.046

      Resource: Coot (RRID:SCR_014222)

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      RRIDCUR:Missing RRID:SCR_014222
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    sciencedirect.com/science/article/pii/S0896627318309541
  225. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.molcel.2018.10.012

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S109727651830844X
  226. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched
    1
    1. scibot 27 Jul 2021
      COOT

      DOI: 10.1016/j.cell.2018.10.026

      Resource: Coot (RRID:SCR_014222)

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      RRIDCUR:Missing RRID:SCR_014222
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    sciencedirect.com/science/article/pii/S0092867418313795
  227. www.sciencedirect.com www.sciencedirect.com
    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
    1
    1. scibot 27 Jul 2021
      Coot

      DOI: 10.1016/j.celrep.2018.10.031

      Resource: Coot (RRID:SCR_014222)

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    sciencedirect.com/science/article/pii/S2211124718316073
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 27 Jul 2021
      SCR_014222

      DOI: 10.1016/j.celrep.2018.11.058

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    ncbi.nlm.nih.gov/pmc/articles/PMC6342559/
  229. Jun 2021
  230. www.sciencedirect.com www.sciencedirect.com
    Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1
    1
    1. scibot 30 Jun 2021
      RRID:SCR_014222

      DOI: 10.1016/j.str.2021.06.005

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    sciencedirect.com/science/article/pii/S0969212621002094
  231. www.sciencedirect.com www.sciencedirect.com
    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
    1
    1. scibot 14 Jun 2021
      RRID:SCR_014222

      DOI: 10.1016/j.cell.2021.04.032

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    sciencedirect.com/science/article/pii/S0092867421005353
  232. May 2021
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
    1
    1. scibot 12 May 2021
      RRID:SCR_014222

      DOI: 10.7554/eLife.65168

      Resource: Coot (RRID:SCR_014222)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8099430/