385 Matching Annotations
  1. Last 7 days
  2. elifesciences.org elifesciences.org
    Control of 3′ splice site selection by the yeast splicing factor Fyv6
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    1. scibot 20 Dec 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.100449

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    elifesciences.org/articles/100449
  3. 52.53.155.43 52.53.155.43
    can-24-2450-html.html
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    1. scibot 19 Dec 2024
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      DOI: 10.1158/0008-5472.can-24-2450

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    52.53.155.43/eda542f05a259fcd2586bec9365306e8eda4954b/can-24-2450-html.html
  4. Dec 2024
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nanobodies against the myelin enzyme CNPase as tools for structural and functional studies
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    1. scibot 13 Dec 2024
      RRID:SCR_014224

      DOI: 10.1111/jnc.16274

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16274
  6. www.sciencedirect.com www.sciencedirect.com
    Structural insights into subunit-dependent functional regulation in epithelial sodium channels
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    1. scibot 12 Dec 2024
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      DOI: 10.1016/j.str.2024.11.013

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    sciencedirect.com/science/article/pii/S0969212624005264
  7. www.sciencedirect.com www.sciencedirect.com
    Dual BACH1 regulation by complementary SCF-type E3 ligases
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    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cell.2024.11.006

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    sciencedirect.com/science/article/pii/S0092867424013229
  8. 52.53.155.43 52.53.155.43
    quinodoz-et-al-2024-de-novo-variants-in-lrrc8c-resulting-in-constitutive-channel-activation-cause-a-human-multisystem-html.html
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    1. scibot 06 Dec 2024
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      DOI: 10.1038/s44318-024-00322-y

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    52.53.155.43/3ab1f2ac64d4a9d1e1b8c8801c1d180b19e6523a/quinodoz-et-al-2024-de-novo-variants-in-lrrc8c-resulting-in-constitutive-channel-activation-cause-a-human-multisystem-html.html
  9. Nov 2024
  10. www.embopress.org www.embopress.org
    Structure of a step II catalytically activated spliceosome from Chlamydomonas reinhardtii
    1
    1. scibot 28 Nov 2024
      RRID:SCR_014224

      DOI: 10.1038/s44318-024-00274-3

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    embopress.org/doi/10.1038/s44318-024-00274-3
  11. www.biorxiv.org www.biorxiv.org
    Inhibition of Parkinson’s Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
    1
    1. scibot 26 Nov 2024
      RRID:SCR_014224

      DOI: 10.1101/2023.09.07.556689

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    biorxiv.org/content/10.1101/2023.09.07.556689v1
  12. www.sciencedirect.com www.sciencedirect.com
    Structural basis of signaling complex inhibition by IL-6 domain-swapped dimers
    1
    1. scibot 24 Nov 2024
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      DOI: 10.1016/j.str.2024.10.028

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    sciencedirect.com/science/article/pii/S0969212624004635
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional implications of the exon 9 splice insert in GluK1 kainate receptors
    1
    1. scibot 10 Nov 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.89755

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    pmc.ncbi.nlm.nih.gov/articles/PMC11540303/
  14. Oct 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Filament formation activates protease and ring nuclease activities of CRISPR Lon-SAVED
    1
    1. scibot 04 Oct 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.09.002

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    sciencedirect.com/science/article/pii/S1097276524007354
  16. Sep 2024
  17. www.biorxiv.org www.biorxiv.org
    Type-II kinase inhibitors that target Parkinson’s Disease-associated LRRK2
    1
    1. scibot 28 Sep 2024
      RRID:SCR_014224

      DOI: 10.1101/2024.09.17.613365

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    biorxiv.org/content/10.1101/2024.09.17.613365v1
  18. www.sciencedirect.com www.sciencedirect.com
    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
    1
    1. scibot 27 Sep 2024
      RRID:SCR_014224

      DOI: 10.1016/j.str.2024.08.022

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    sciencedirect.com/science/article/pii/S0969212624003691
  19. www.sciencedirect.com www.sciencedirect.com
    Conformational Plasticity in the HIV-1 Fusion Peptide Facilitates Recognition by Broadly Neutralizing Antibodies
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.chom.2019.04.011

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    sciencedirect.com/science/article/pii/S1931312819302148
  20. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
    1
    1. scibot 17 Sep 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  21. Aug 2024
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of the human heparan-α-glucosaminide N-acetyltransferase (HGSNAT)
    1
    1. scibot 30 Aug 2024
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      DOI: 10.7554/eLife.93510

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    ncbi.nlm.nih.gov/pmc/articles/PMC11357348/
  23. www.sciencedirect.com www.sciencedirect.com
    Conservation and specialization of the Ycf2-FtsHi chloroplast protein import motor in green algae
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.cell.2024.08.002

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    sciencedirect.com/science/article/pii/S0092867424008936
  24. www.cell.com www.cell.com
    Structural insights into the chloroplast protein import in land plants
    1
    1. scibot 28 Aug 2024
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      DOI: 10.1016/j.cell.2024.08.003

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    cell.com/cell/fulltext/S0092-8674(24)00894-8
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    Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance
    1
    1. scibot 28 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.07.048

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    sciencedirect.com/science/article/pii/S0092867424008420
  26. www.sciencedirect.com www.sciencedirect.com
    Hybrid immunity to SARS-CoV-2 arises from serological recall of IgG antibodies distinctly imprinted by infection or vaccination
    1
    1. scibot 18 Aug 2024
      RRID:SCR_014224

      DOI: 10.1016/j.xcrm.2024.101668

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    sciencedirect.com/science/article/pii/S2666379124003823
  27. europepmc.orghttp europepmc.orghttp
    Structural Basis for a Safety-Belt Mechanism That Anchors Condensin to Chromosomes
    1
    1. scibot 02 Aug 2024
      Phenix suite

      DOI: 10.1016/j.cell.2017.09.008

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    europepmc.orghttp//europepmc.org/articles/PMC5651216/
  28. www.proquest.com www.proquest.com
    Mechanism of Ca2+ transport by ferroportin - ProQuest
    1
    1. scibot 02 Aug 2024
      RRID:SCR_014224

      DOI: 10.7554/eLife.82947

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    proquest.com/docview/2771288630
  29. Jul 2024
  30. www.sciencedirect.com www.sciencedirect.com
    Structure of the Hir histone chaperone complex
    1
    1. scibot 24 Jul 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.05.031

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    sciencedirect.com/science/article/pii/S1097276524004787
  31. www.sciencedirect.com www.sciencedirect.com
    An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II
    1
    1. scibot 19 Jul 2024
      RRID:SCR_014224

      DOI: 10.1016/j.molcel.2024.06.006

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    sciencedirect.com/science/article/pii/S1097276524004842
  32. www.sciencedirect.com www.sciencedirect.com
    Crimean-Congo hemorrhagic fever survivors elicit protective non-neutralizing antibodies that target 11 overlapping regions on glycoprotein GP38
    1
    1. scibot 16 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114502

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    sciencedirect.com/science/article/pii/S2211124724008313
  33. Jun 2024
  34. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.jbc.2024.107469

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    sciencedirect.com/science/article/pii/S0021925824019707
  35. www.cell.com www.cell.com
    Mechanism of heterochromatin remodeling revealed by the DDM1 bound nucleosome structures
    1
    1. scibot 21 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.str.2024.05.013

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    cell.com/structure/fulltext/S0969-2126(24)00190-4
  36. www.cell.com www.cell.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.05.002

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    cell.com/cell/fulltext/S0092-8674(24)00493-8
  37. www.sciencedirect.com www.sciencedirect.com
    Cryo-electron tomography reveals the packaging pattern of RuBisCOs in Synechococcus β-carboxysome
    1
    1. scibot 04 Jun 2024
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      DOI: 10.1016/j.str.2024.05.007

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    sciencedirect.com/science/article/pii/S0969212624001849
  38. May 2024
  39. www.sciencedirect.com www.sciencedirect.com
    A targeted single mutation in influenza A virus universal epitope transforms immunogenicity and protective immunity via CD4+ T cell activation
    1
    1. scibot 31 May 2024
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2024.114259

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    sciencedirect.com/science/article/pii/S2211124724005874
  40. Apr 2024
  41. www.sciencedirect.com www.sciencedirect.com
    Eliciting a single amino acid change by vaccination generates antibody protection against group 1 and group 2 influenza A viruses
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.immuni.2024.03.022

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    sciencedirect.com/science/article/pii/S1074761324001432
  42. www.nature.com www.nature.com
    Visualizing chaperone-mediated multistep assembly of the human 20S proteasome
    1
    1. scibot 11 Apr 2024
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      DOI: 10.1038/s41594-024-01268-9

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    nature.com/articles/s41594-024-01268-9
  43. www.sciencedirect.com www.sciencedirect.com
    Staphylococcus aureus skin colonization is mediated by SasG lectin variation
    1
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      DOI: 10.1016/j.celrep.2024.114022

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    sciencedirect.com/science/article/pii/S2211124724003504
  44. www.cell.com www.cell.com
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
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      DOI: 10.1016/j.celrep.2024.114035

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    cell.com/cell-reports/fulltext/S2211-1247(24)00363-2
  45. Mar 2024
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural mechanisms for VMAT2 inhibition by tetrabenazine
    1
    1. scibot 27 Mar 2024
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      DOI: 10.7554/eLife.91973

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    ncbi.nlm.nih.gov/pmc/articles/PMC10959523/
  47. www.sciencedirect.com www.sciencedirect.com
    Convergent evolution and targeting of diverse E2 epitopes by human broadly neutralizing antibodies are associated with HCV clearance
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      DOI: 10.1016/j.immuni.2024.03.001

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    sciencedirect.com/science/article/pii/S1074761324000979
  48. www.sciencedirect.com www.sciencedirect.com
    ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat
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      DOI: 10.1016/j.cell.2024.02.013

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    2. scibot 15 Mar 2024
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      DOI: 10.1016/j.cell.2024.02.013

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    sciencedirect.com/science/article/pii/S009286742400179X
  49. www.sciencedirect.com www.sciencedirect.com
    Structure of the plant plastid-encoded RNA polymerase
    2
    1. scibot 01 Mar 2024
      RRID:SCR_014224

      DOI: 10.1016/j.cell.2024.01.036

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    2. scibot 01 Mar 2024
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      DOI: 10.1016/j.cell.2024.01.036

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    sciencedirect.com/science/article/pii/S009286742400103X
  50. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM structures of the plant plastid-encoded RNA polymerase
    1
    1. scibot 01 Mar 2024
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      DOI: 10.1016/j.cell.2024.01.026

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    sciencedirect.com/science/article/pii/S0092867424000631
  51. Feb 2024
  52. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
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      DOI: 10.7554/eLife.39611

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  53. Dec 2023
  54. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
    1
    1. scibot 20 Dec 2023
      RRID:SCR_014224

      DOI: 10.1016/j.celrep.2023.113516

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  55. www.sciencedirect.com www.sciencedirect.com
    Titin domains with reduced core hydrophobicity cause dilated cardiomyopathy
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      DOI: 10.1016/j.celrep.2023.113490

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  56. www.sciencedirect.com www.sciencedirect.com
    Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense
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      DOI: 10.1016/j.molcel.2023.11.007

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    sciencedirect.com/science/article/pii/S1097276523009498
  57. Nov 2023
  58. www.sciencedirect.com www.sciencedirect.com
    Leveraging vaccination-induced protective antibodies to define conserved epitopes on influenza N2 neuraminidase
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    1. scibot 18 Nov 2023
      RRID:SCR_014224

      DOI: 10.1016/j.immuni.2023.10.005

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  59. www.cell.com www.cell.com
    Architecture of the bacteriophage lambda tail
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      DOI: 10.1016/j.str.2023.10.006

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  60. www.sciencedirect.com www.sciencedirect.com
    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
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      DOI: 10.1016/j.cell.2023.10.002

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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Energy coupling and stoichiometry of Zn2+/H+ antiport by the prokaryotic cation diffusion facilitator YiiP
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      DOI: 10.7554/eLife.87167

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  62. Oct 2023
  63. www.sciencedirect.com www.sciencedirect.com
    KANK1 shapes focal adhesions by orchestrating protein binding, mechanical force sensing, and phase separation
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113321

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  64. www.nature.com www.nature.com
    A Legionella toxin exhibits tRNA mimicry and glycosyl transferase activity to target the translation machinery and trigger a ribotoxic stress response
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      DOI: 10.1038/s41556-023-01248-z

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  65. Sep 2023
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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    1. scibot 08 Sep 2023
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      DOI: 10.1158/2159-8290.CD-23-0475

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  67. Aug 2023
  68. 52.53.155.43 52.53.155.43
    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
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      DOI: 10.1016/j.isci.2023.107579

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  69. 52.53.155.43 52.53.155.43
    Structural insights into anion selectivity and activation mechanism of LRRC8 volume-regulated anion channels
    2
    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112926

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  70. Jul 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Structural definition of HLA class II-presented SARS-CoV-2 epitopes reveals a mechanism to escape pre-existing CD4+ T cell immunity
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112827

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
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      DOI: 10.7554/eLife.86029

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  73. 52.53.155.43 52.53.155.43
    cd-23-0475-html.html
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      DOI: 10.1158/2159-8290.cd-23-0475

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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange
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      DOI: 10.7554/eLife.87178

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  75. Jun 2023
  76. www.sciencedirect.com www.sciencedirect.com
    A structural blueprint for interleukin-21 signal modulation
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    1. scibot 21 Jun 2023
      SCR_014224

      DOI: 10.1016/j.celrep.2023.112657

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  77. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
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    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.036

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  78. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.007

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  79. May 2023
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High-resolution structures with bound Mn2+ and Cd2+ map the metal import pathway in an Nramp transporter
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      DOI: 10.7554/eLife.84006

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  81. www.sciencedirect.com www.sciencedirect.com
    Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response
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      DOI: 10.1016/j.str.2023.04.010

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    sciencedirect.com/science/article/pii/S0969212623001338
  82. Apr 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of the endothelin-1-ETB-Gi complex
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    1. scibot 29 Apr 2023
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      DOI: 10.7554/eLife.85821

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    ncbi.nlm.nih.gov/pmc/articles/PMC10129325/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and functional properties of a plant NRAMP-related aluminum transporter
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    1. scibot 27 Apr 2023
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      DOI: 10.7554/eLife.85641

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    ncbi.nlm.nih.gov/pmc/articles/PMC10115441/
  85. www.sciencedirect.com www.sciencedirect.com
    Machine learning predictions of MHC-II specificities reveal alternative binding mode of class II epitopes
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      DOI: 10.1016/j.immuni.2023.03.009

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    sciencedirect.com/science/article/pii/S1074761323001292
  86. Mar 2023
  87. www.sciencedirect.com www.sciencedirect.com
    Immunodominant surface epitopes power immune evasion in the African trypanosome
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      DOI: 10.1016/j.celrep.2023.112262

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    sciencedirect.com/science/article/pii/S2211124723002735
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
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      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  89. Feb 2023
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for ATG9A recruitment to the ULK1 complex in mitophagy initiation
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      RRID:SCR_0142294

      DOI: 10.1126/sciadv.adg2997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9931213/
  91. www.sciencedirect.com www.sciencedirect.com
    Structural basis of a transcription pre-initiation complex on a divergent promoter
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      DOI: 10.1016/j.molcel.2023.01.011

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanism of Ca2+ transport by ferroportin
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      DOI: 10.7554/eLife.82947

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    ncbi.nlm.nih.gov/pmc/articles/PMC9883014/
  93. Jan 2023
  94. www.sciencedirect.com www.sciencedirect.com
    Nucleosome dyad determines the H1 C-terminus collapse on distinct DNA arms
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      DOI: 10.1016/j.str.2022.12.005

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  95. Dec 2022
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of human phagocyte NADPH oxidase in the resting state
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      DOI: 10.7554/eLife.83743

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    ncbi.nlm.nih.gov/pmc/articles/PMC9711523/
  97. Nov 2022
  98. www.sciencedirect.com www.sciencedirect.com
    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
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      DOI: 10.1016/j.cell.2022.10.030

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
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      DOI: 10.1016/j.immuni.2022.10.019

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    ncbi.nlm.nih.gov/pmc/articles/PMC9606073/
  100. www.sciencedirect.com www.sciencedirect.com
    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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      DOI: 10.1016/j.celrep.2022.111489

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    sciencedirect.com/science/article/pii/S2211124722013390
  101. Oct 2022
  102. www.sciencedirect.com www.sciencedirect.com
    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
    1
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      DOI: 10.1016/j.cmet.2022.09.001

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  103. Sep 2022
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
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      DOI: 10.7554/eLife.79148

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  105. Aug 2022
  106. www.sciencedirect.com www.sciencedirect.com
    Structure of a fully assembled tumor-specific T cell receptor ligated by pMHC
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      DOI: 10.1016/j.cell.2022.07.010

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  107. Jul 2022
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conserved structural elements specialize ATAD1 as a membrane protein extraction machine
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      DOI: 10.7554/eLife.73941

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  109. Jun 2022
  110. www.cell.com www.cell.com
    Rational exploration of fold atlas for human solute carrier proteins
    1
    1. scibot 15 Jun 2022
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      DOI: 10.1016/j.str.2022.05.015

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    cell.com/structure/fulltext/S0969-2126(22)00189-7
  111. www.sciencedirect.com www.sciencedirect.com
    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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      DOI: 10.1016/j.cell.2022.04.016

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    sciencedirect.com/science/article/pii/S0092867422004639
  112. May 2022
  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
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    1. scibot 21 May 2022
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      DOI: 10.7554/eLife.77696

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    ncbi.nlm.nih.gov/pmc/articles/PMC9113749/
  114. Apr 2022
  115. www.sciencedirect.com www.sciencedirect.com
    Basis for drug selectivity of plasmepsin IX and X inhibition in Plasmodium falciparum and vivax
    1
    1. scibot 28 Apr 2022
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      DOI: 10.1016/j.str.2022.03.018

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  116. www.sciencedirect.com www.sciencedirect.com
    RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex
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    sciencedirect.com/science/article/pii/S2211124722004934
  117. www.sciencedirect.com www.sciencedirect.com
    Structure of the poxvirus decapping enzyme D9 reveals its mechanism of cap recognition and catalysis
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis Of Memory B Cells Identifies Conserved Neutralizing Epitopes On The N-Terminal Domain Of Variant SARS-Cov-2 Spike Proteins
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      DOI: 10.1016/j.immuni.2022.04.003

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  119. Mar 2022
  120. www.cell.com www.cell.com
    Facile discovery of surrogate cytokine agonists
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    cell.com/cell/fulltext/S0092-8674(22)00247-1
  121. www.sciencedirect.com www.sciencedirect.com
    Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis for an unprecedented enzymatic alkylation in cylindrocyclophane biosynthesis
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      DOI: 10.7554/eLife.75761

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    ncbi.nlm.nih.gov/pmc/articles/PMC8916777/
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of nanobodies neutralizing SARS-CoV-2 variants
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystals of TELSAM–target protein fusions that exhibit minimal crystal contacts and lack direct inter-TELSAM contacts
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      DOI: 10.1098/rsob.210271

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    ncbi.nlm.nih.gov/pmc/articles/PMC8889177/
  125. www.sciencedirect.com www.sciencedirect.com
    Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure and ion-release mechanism of PIB-4-type ATPases
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    ncbi.nlm.nih.gov/pmc/articles/PMC8880997/
  127. www.sciencedirect.com www.sciencedirect.com
    Structural insights into DNMT5-mediated ATP-dependent high-fidelity epigenome maintenance
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      DOI: 10.1016/j.molcel.2022.01.028

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    sciencedirect.com/science/article/pii/S1097276522001046
  128. www.sciencedirect.com www.sciencedirect.com
    Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel
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    sciencedirect.com/science/article/pii/S0969212622000417
  129. www.sciencedirect.com www.sciencedirect.com
    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
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      DOI: 10.1016/j.devcel.2022.02.008

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    sciencedirect.com/science/article/pii/S1534580722000740
  130. Feb 2022
  131. elifesciences.org elifesciences.org
    Fluorescence activation mechanism and imaging of drug permeation with new sensors for smoking-cessation ligands
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      RRID:SCR_014224

      DOI: 10.7554/eLife.74648

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    elifesciences.org/articles/74648
  132. elifesciences.org elifesciences.org
    Structural basis of Plasmodium vivax inhibition by antibodies binding to the circumsporozoite protein repeats
    2
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      RRID:SCR_014224

      DOI: 10.7554/eLife.72908

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      DOI: 10.7554/eLife.72908

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    elifesciences.org/articles/72908
  133. elifesciences.org elifesciences.org
    Structural and functional properties of a magnesium transporter of the SLC11/NRAMP family
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      DOI: 10.7554/eLife.74589

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    elifesciences.org/articles/74589
  134. Jan 2022
  135. elifesciences.org elifesciences.org
    Nanofluidic chips for cryo-EM structure determination from picoliter sample volumes
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    1. scibot 28 Jan 2022
      RRID:SCR_014224v1

      DOI: 10.7554/eLife.72629

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    elifesciences.org/articles/72629
  136. www.cell.com www.cell.com
    Structural basis of bacteriophage lambda capsid maturation
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      DOI: 10.1016/j.str.2021.12.009

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    cell.com/structure/fulltext/S0969-2126(21)00461-5
  137. www.sciencedirect.com www.sciencedirect.com
    Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II
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      DOI: 10.1016/j.molcel.2021.12.020

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    sciencedirect.com/science/article/pii/S1097276521010820
  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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      DOI: 10.7554/eLife.72823

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    ncbi.nlm.nih.gov/pmc/articles/PMC8758145/
  139. Dec 2021
  140. www.sciencedirect.com www.sciencedirect.com
    Rational engineering enables co-crystallization and structural determination of the HIV-1 matrix-tRNA complex
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      RRID:SCR_014224

      DOI: 10.1016/j.xpro.2021.101056

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    sciencedirect.com/science/article/pii/S2666166721007620
  141. Nov 2021
  142. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
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      DOI: 10.1016/j.str.2021.10.004

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    sciencedirect.com/science/article/pii/S0969212621003725
  143. Oct 2021
  144. www.sciencedirect.com www.sciencedirect.com
    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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      RRID:SCR_014224

      DOI: 10.1016/j.cell.2021.09.035

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    sciencedirect.com/science/article/pii/S009286742101165X
  145. www.cell.com www.cell.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
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      DOI: 10.1016/j.celrep.2021.109877

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    cell.com/cell-reports/fulltext/S2211-1247(21)01347-4
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the cis and trans assembly of human trophoblast cell surface antigen 2
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      DOI: 10.1016/j.isci.2021.103190

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    ncbi.nlm.nih.gov/pmc/articles/PMC8517388/
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural characterization of NrnC identifies unifying features of dinucleotidases
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      DOI: 10.7554/eLife.70146

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    ncbi.nlm.nih.gov/pmc/articles/PMC8492067/
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural insights into the activation of human calcium-sensing receptor
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      DOI: 10.7554/eLife.68578

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    ncbi.nlm.nih.gov/pmc/articles/PMC8476121/
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
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      DOI: 10.7554/eLife.71474

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  150. Sep 2021
  151. elifesciences.org elifesciences.org
    Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
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      DOI: 10.7554/eLife.71420

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    elifesciences.org/articles/71420
  152. www.sciencedirect.com www.sciencedirect.com
    Structural basis and regulation of the reductive stress response
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      DOI: 10.1016/j.cell.2021.09.002

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    sciencedirect.com/science/article/pii/S0092867421010497
  153. www.sciencedirect.com www.sciencedirect.com
    Atypical TNF-TNFR superfamily binding interface in the GITR-GITRL complex for T cell activation
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    sciencedirect.com/science/article/pii/S2211124721011839
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Broad cross-reactivity across sarbecoviruses exhibited by a subset of COVID-19 donor-derived neutralizing antibodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8423902/
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
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      DOI: 10.7554/eLife.70871

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    ncbi.nlm.nih.gov/pmc/articles/PMC8439649/
  156. www.sciencedirect.com www.sciencedirect.com
    Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
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      DOI: 10.1016/j.cell.2021.08.012

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  157. www.sciencedirect.com www.sciencedirect.com
    High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor
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    sciencedirect.com/science/article/pii/S0969212621002963
  158. Aug 2021
  159. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
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    1. scibot 25 Aug 2021
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      DOI: 10.7554/eLife.68110

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  160. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    McsB forms a gated kinase chamber to mark aberrant bacterial proteins for degradation
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      DOI: 10.7554/eLife.63505

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    ncbi.nlm.nih.gov/pmc/articles/PMC8370763/
  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
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    A Rare Lysozyme Crystal Form Solved Using Highly Redundant Multiple Electron Diffraction Datasets from Micron-Sized Crystals
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    Fcab-HER2 Interaction: a Ménage à Trois. Lessons from X-Ray and Solution Studies
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    Cryo-EM structures of the caspase-activated protein XKR9 involved in apoptotic lipid scrambling
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    Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex
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    High resolution cryo-EM structure of the helical RNA-bound Hantaan virus nucleocapsid reveals its assembly mechanisms
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    Regulation of the endosomal SNX27-retromer by OTULIN
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    Structure of the thermo-sensitive TRP channel TRP1 from the alga Chlamydomonas reinhardtii
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    Crystal structures of DNA polymerase I capture novel intermediates in the DNA synthesis pathway
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    Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer
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    Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues
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    Structural and functional characterization of an otopetrin family proton channel
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    Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor
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    Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition
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    Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins
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    Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis
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    Structural Basis for Cholesterol Transport-like Activity of the Hedgehog Receptor Patched
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    A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
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  204. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.str.2018.06.006

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    sciencedirect.com/science/article/pii/S0969212618302120
  205. www.sciencedirect.com www.sciencedirect.com
    Structural Basis of Mitochondrial Transcription Initiation
    1
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      DOI: 10.1016/j.cell.2017.10.036

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    sciencedirect.com/science/article/pii/S009286741731262X
  206. Jun 2021
  207. www.sciencedirect.com www.sciencedirect.com
    Identification of an atypical interaction site in the BTB domain of the MYC-interacting zinc-finger protein 1
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    sciencedirect.com/science/article/pii/S0969212621002094
  208. www.sciencedirect.com www.sciencedirect.com
    B cell genomics behind cross-neutralization of SARS-CoV-2 variants and SARS-CoV
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      DOI: 10.1016/j.cell.2021.04.032

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  209. May 2021
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CM1-driven assembly and activation of yeast γ-tubulin small complex underlies microtubule nucleation
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      DOI: 10.7554/eLife.65168

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    ncbi.nlm.nih.gov/pmc/articles/PMC8099430/
  211. www.sciencedirect.com www.sciencedirect.com
    The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
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    sciencedirect.com/science/article/pii/S0969212620302112
  212. www.sciencedirect.com www.sciencedirect.com
    Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
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    sciencedirect.com/science/article/pii/S1097276520307802
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    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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  214. Apr 2021
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    Structural insights into viral RNA capping and plasma membrane targeting by Chikungunya virus nonstructural protein 1
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      DOI: 10.1016/j.chom.2021.02.018

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    Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells
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    Cellular mRNA triggers structural transformation of Ebola virus matrix protein VP40 to its essential regulatory form
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    sciencedirect.com/science/article/pii/S2211124721003004
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    The tissue protective functions of interleukin-22 can be decoupled from pro-inflammatory actions through structure-based design
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    sciencedirect.com/science/article/pii/S1074761321001205
  219. www.cell.com www.cell.com
    SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms
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    cell.com/cell/fulltext/S0092-8674(21)00355-X
  220. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
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  221. Mar 2021
  222. www.cell.com www.cell.com
    Structure and immune recognition of the porcine epidemic diarrhea virus spike protein
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    cell.com/structure/fulltext/S0969-2126(20)30470-6
  223. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7924943/
  224. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
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      DOI: 10.7554/eLife.64690

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    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
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    sciencedirect.com/science/article/pii/S1097276520309540
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    Vaccination induces maturation in a mouse model of diverse unmutated VRC01-class precursors to HIV-neutralizing antibodies with >50% breadth
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      DOI: 10.1016/j.immuni.2020.12.014

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    sciencedirect.com/science/article/pii/S1074761320305422
  227. Feb 2021
  228. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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      DOI: 10.7554/eLife.56664

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  229. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
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      DOI: 10.7554/eLife.59991

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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  230. www.cell.com www.cell.com
    Calmodulin binds to Drosophila TRP with an unexpected mode
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    cell.com/structure/abstract/S0969-2126(20)30463-9
  231. elifesciences.org elifesciences.org
    A processive rotary mechanism couples substrate unfolding and proteolysis in the ClpXP degradation machinery
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      DOI: 10.7554/eLife.52158

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    elifesciences.org/articles/52158
  232. www.cell.com www.cell.com
    Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody
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    cell.com/cell/abstract/S0092-8674(20)30057-X
  233. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site
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      DOI: 10.7554/eLife.50661

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    ncbi.nlm.nih.gov/pmc/articles/PMC6957272/
  234. www.cell.com www.cell.com
    Mimicry of Canonical Translation Elongation Underlies Alanine Tail Synthesis in RQC
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      DOI: 10.1016/j.molcel.2020.11.001

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30779-6
  235. Jan 2021
  236. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutations in SKI in Shprintzen–Goldberg syndrome lead to attenuated TGF-β responses through SKI stabilization
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      DOI: 10.7554/eLife.63545

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  237. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
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      DOI: 10.7554/eLife.62047

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  238. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of bacterial phospholipid transporter MlaFEDB with substrate bound
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      DOI: 10.7554/eLife.62518

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    ncbi.nlm.nih.gov/pmc/articles/PMC7790496/
  239. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients
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      DOI: 10.7554/eLife.62611

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