114 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
    1
    1. scibot 17 May 2024
      RRID:SCR_014246

      DOI: 10.1158/1078-0432.CCR-23-1763

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    ncbi.nlm.nih.gov/pmc/articles/PMC11094420/
  3. May 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
    1
    1. scibot 02 May 2024
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      DOI: 10.1016/j.neuron.2024.04.006

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    sciencedirect.com/science/article/pii/S0896627324002447
  5. Feb 2024
  6. 52.53.155.43 52.53.155.43
    HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
    1
    1. scibot 23 Feb 2024
      RRID:SCR_014246

      DOI: 10.1101/2023.10.16.562477

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    52.53.155.43/893a986f25098b75e101f0b7cb970068940c81b3/2023.10.16.562477v2.full-html.html
  7. elifesciences.org elifesciences.org
    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
    1
    1. scibot 08 Feb 2024
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      DOI: 10.7554/eLife.39611

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    elifesciences.org/articles/39611
  8. Dec 2023
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
    1
    1. scibot 15 Dec 2023
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      DOI: 10.1371/journal.pgen.1011043

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    ncbi.nlm.nih.gov/pmc/articles/PMC10715669/
  10. Aug 2023
  11. link.springer.com link.springer.com
    Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
    1
    1. scibot 23 Aug 2023
      RRID:SCR_014246

      DOI: 10.1186/s40478-023-01633-7

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    link.springer.com/article/10.1186/s40478-023-01633-7
  12. Jul 2023
  13. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
    1
    1. scibot 05 Jul 2023
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      DOI: 10.1111/jnc.15900

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15900
  14. Mar 2023
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
    1
    1. scibot 09 Mar 2023
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      DOI: 10.7554/eLife.82821

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    ncbi.nlm.nih.gov/pmc/articles/PMC9988257/
  16. Jan 2023
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
    1
    1. scibot 14 Jan 2023
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      DOI: 10.1111/jnc.15732

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15732
  18. Dec 2022
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity
    1
    1. scibot 31 Dec 2022
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      DOI: 10.7554/eLife.81897

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    ncbi.nlm.nih.gov/pmc/articles/PMC9762709/
  20. link.springer.com link.springer.com
    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
    1
    1. scibot 13 Dec 2022
      RRID:SCR_014246

      DOI: 10.1186/s10020-022-00581-7

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    link.springer.com/article/10.1186/s10020-022-00581-7
  21. Nov 2022
  22. www.researchsquare.com www.researchsquare.com
    Home
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    1. scibot 11 Nov 2022
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      DOI: 10.21203/rs.3.rs-658360/v1

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  23. rupress.org rupress.org
    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
    1
    1. scibot 01 Nov 2022
      RRID:SCR_014246

      DOI: 10.1083/jcb.202207022

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    rupress.org/jcb/article/221/12/e202207022/213573/Mitoguardin-2-mediated-lipid-transfer-preserves
  24. Oct 2022
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III
    1
    1. scibot 27 Oct 2022
      RRID:SCR_014246

      DOI: 10.1016/j.isci.2022.105306

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    ncbi.nlm.nih.gov/pmc/articles/PMC9593817/
  26. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
    1
    1. scibot 25 Oct 2022
      RRID:SCR_014246

      DOI: 10.1186/s13195-022-01096-3

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    alzres.biomedcentral.com/articles/10.1186/s13195-022-01096-3
  27. Jun 2022
  28. www.sciencedirect.com www.sciencedirect.com
    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
    1
    1. scibot 03 Jun 2022
      RRID:SCR_014246

      DOI: 10.1016/j.celrep.2022.110889

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    sciencedirect.com/science/article/pii/S2211124722006647
  29. www.sciencedirect.com www.sciencedirect.com
    A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.molcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1097276522003835
  30. May 2022
  31. elifesciences.org elifesciences.org
    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
    1
    1. scibot 11 May 2022
      RRID:SCR_014246

      DOI: 10.7554/eLife.62625

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    elifesciences.org/articles/62625
  32. Apr 2022
  33. www.sciencedirect.com www.sciencedirect.com
    A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme
    1
    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.chom.2022.03.001

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    sciencedirect.com/science/article/pii/S1931312822001305
  34. Mar 2022
  35. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Cardiomyocyte substructure reverts to an immature phenotype during heart failure
    1
    1. scibot 26 Mar 2022
      RRID:SCR_014246

      DOI: 10.1113/JP277273

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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP277273
  36. www.eneuro.org www.eneuro.org
    The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2
    1
    1. scibot 08 Mar 2022
      RRID:SCR_014246

      DOI: 10.1523/ENEURO.0409-21.2022

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    eneuro.org/content/9/2/ENEURO.0409-21.2022
  37. Jan 2022
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
    1
    1. scibot 07 Jan 2022
      RRID:SCR_014246

      DOI: 10.7554/eLife.68213

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    ncbi.nlm.nih.gov/pmc/articles/PMC8719881/
  39. Oct 2021
  40. www.sciencedirect.com www.sciencedirect.com
    Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
    1
    1. scibot 23 Oct 2021
      RRID:SCR_014246

      DOI: 10.1016/j.molcel.2021.10.003

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    sciencedirect.com/science/article/pii/S1097276521008327
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SUMOylation contributes to proteostasis of the chloroplast protein import receptor TOC159 during early development
    1
    1. scibot 11 Oct 2021
      RRID:SCR_014246

      DOI: 10.7554/eLife.60968

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    ncbi.nlm.nih.gov/pmc/articles/PMC8497054/
  42. Aug 2021
  43. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Untitled document
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    1. scibot 08 Aug 2021
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      DOI: 10.1002/jcp.26330

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    onlinelibrary.wiley.com/doi/10.1002/jcp.26330/full
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis
    1
    1. scibot 08 Aug 2021
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      DOI: 10.7554/eLife.32572

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    ncbi.nlm.nih.gov/pmc/articles/PMC5809144/
  45. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Untitled document
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    1. scibot 06 Aug 2021
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      DOI: 10.1113/JP276714

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    physoc.onlinelibrary.wiley.com/doi/full/10.1113/JP276714
  46. www.sciencedirect.com www.sciencedirect.com
    Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation
    1
    1. scibot 06 Aug 2021
      RRID:SCR_04246

      DOI: 10.1016/j.molcel.2021.07.013

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    sciencedirect.com/science/article/pii/S1097276521005827
  47. Jul 2021
  48. www.mdpi.com www.mdpi.com
    Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing
    1
    1. scibot 31 Jul 2021
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      DOI: 10.3390/biom9100584

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    mdpi.com/2218-273X/9/10/584/htm
  49. www.embopress.org www.embopress.org
    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
    1
    1. scibot 30 Jul 2021
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      DOI: 10.15252/embr.201947728

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    embopress.org/doi/full/10.15252/embr.201947728
  50. advances.sciencemag.org advances.sciencemag.org
    RNA binding activates RIG-I by releasing an autorepressed signaling domain
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1126/sciadv.aax3641

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    advances.sciencemag.org/content/5/10/eaax3641.full
  51. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Mechanisms underlying TNFα‐induced enhancement of force generation in airway smooth muscle
    1
    1. scibot 30 Jul 2021
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      DOI: 10.14814/phy2.14220

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    physoc.onlinelibrary.wiley.com/doi/10.14814/phy2.14220
  52. academic.oup.com academic.oup.com
    Regulation of BTB dynamics in spermatogenesis – insights from the adjudin toxicant model
    1
    1. scibot 30 Jul 2021
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      DOI: 10.1093/toxsci/kfz180

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    academic.oup.com/toxsci/advance-article/doi/10.1093/toxsci/kfz180/5545528
  53. elifesciences.org elifesciences.org
    Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria
    1
    1. scibot 30 Jul 2021
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      DOI: 10.7554/eLife.32032

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    elifesciences.org/articles/32032
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel smoothened antagonists as anti‐neoplastic agents for the treatment of osteosarcoma
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      DOI: 10.1002/jcp.26330

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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.26330
  55. www.sciencedirect.com www.sciencedirect.com
    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1016/j.neuron.2019.08.017

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    sciencedirect.com/science/article/pii/S0896627319307019
  56. www.sciencedirect.com www.sciencedirect.com
    Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
    1
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      DOI: 10.1016/j.celrep.2019.05.073

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    sciencedirect.com/science/article/pii/S2211124719307028
  57. journals.plos.org journals.plos.org
    The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1371/journal.ppat.1007963

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    journals.plos.org/plospathogens/article
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 29 Jul 2021
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      DOI: 10.1111/bph.14777

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    bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14777
  59. www.jneurosci.org www.jneurosci.org
    Protein Kinase C Lambda Mediates Acid-Sensing Ion Channel 1a-Dependent Cortical Synaptic Plasticity and Pain Hypersensitivity
    1
    1. scibot 29 Jul 2021
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      DOI: 10.1523/JNEUROSCI.0213-19.2019

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    jneurosci.org/content/39/29/5773
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.27283

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    ncbi.nlm.nih.gov/pmc/articles/PMC5552277/
  61. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms
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  63. elifesciences.org elifesciences.org
    Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
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    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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    COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis
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    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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  67. europepmc.org europepmc.org
    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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  68. May 2021
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    Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells
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    Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon
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    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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  74. Feb 2021
  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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    Homogentisic acid affects human osteoblastic functionality by oxidative stress and alteration of the Wnt/β‐catenin signaling pathway
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  77. Jan 2021
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    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
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    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
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    TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
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    Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments
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  87. Sep 2020
  88. journals.plos.org journals.plos.org
    Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins
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  89. elifesciences.org elifesciences.org
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  90. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects
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    Extraction of mRNA from Stalled Ribosomes by the Ski Complex
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  96. Jan 2020
  97. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Murine maternal dietary restriction affects neural Humanin expression and cellular profile
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      DOI: 10.1002/jnr.24568

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    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
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    Evolution of (p)ppGpp-HPRT regulation through diversification of an allosteric oligomeric interaction
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrially-targeted APOBEC1 is a potent mtDNA mutator affecting mitochondrial function and organismal fitness in Drosophila
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  101. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
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    Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning
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      DOI: 10.1016/j.cels.2018.09.002

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    A Chaperone Lid Ensures Efficient and Privileged Client Transfer during Tail-Anchored Protein Targeting
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  105. onlinelibrary.wiley.com onlinelibrary.wiley.com
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  106. Nov 2018
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival
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    Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition
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    The cAMP-EPAC Pathway Mediates PGE2-Induced FGF2 in Bovine Granulosa Cells
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    Pb inhibits hippocampal synaptic transmission via cyclin-dependent kinase-5 dependent Synapsin 1 phosphorylation
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    Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins
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    Stable STIM1 Knockdown in Self-Renewing Human Neural Precursors Promotes Premature Neural Differentiation
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    The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor
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    Restoration of Replication Fork Stability in BRCA1- and BRCA2-Deficient Cells by Inactivation of SNF2-Family Fork Remodelers
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    Structure and topology around the cleavage site regulate post-translational cleavage of the HIV-1 gp160 signal peptide
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    The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention
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    Phosphorylation of Synaptic GTPase-activating Protein (synGAP) by Ca2+/Calmodulin-dependent Protein Kinase II (CaMKII) and Cyclin-dependent Kinase 5 (CDK5) Alters the Ratio of Its GAP Activity toward Ras and Rap GTPases
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