131 Matching Annotations
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    Preclinical Evaluation of PTK7-Targeted Radionuclide Therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12402794/
  3. Aug 2025
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    Ceramide transfer protein regulates G-protein coupled phospholipase signalling in Drosophila photoreceptors
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    biorxiv.org/content/10.1101/2025.08.05.668821v1
  5. May 2025
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    Ca2+ binding to Esyt modulates membrane contact site density in Drosophila photoreceptors
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    eIF5A controls mitoprotein import by relieving ribosome stalling at TIM50 translocase mRNA
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  8. Apr 2025
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    Altered Mitochondrial Bioenergetics and Calcium Kinetics in Young‐Onset PLA2G6 Parkinson's Disease iPSCs
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  10. Feb 2025
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    Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling
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  12. Dec 2024
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    Activity-dependent COX-2 proteolysis modulates aerobic respiration and proliferation in a prostaglandin-independent manner
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  14. Nov 2024
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    HERC3 facilitates ERAD of select membrane proteins by recognizing membrane-spanning domains
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    Molecular basis of neurodegeneration in a mouse model of Polr3-related disease
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  17. Sep 2024
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    Pretargeted Radioimmunotherapy with the Novel Anti-oxMIF/HSG Bispecific Antibody ON105 Results in Significant Tumor Regression in Murine Models of Cancer
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    A chemical screen identifies PRMT5 as a therapeutic vulnerability for paclitaxel-resistant triple-negative breast cancer
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  20. Aug 2024
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    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    Galectin-3 induces pathogenic immunosuppressive macrophages through interaction with TREM2 in lung cancer
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    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
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  24. Jul 2024
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    Tumor invasiveness is regulated by the concerted function of APC, formins and Arp2/3 complex
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  26. Jun 2024
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    POT1 recruits and regulates CST-Polα/primase at human telomeres
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  29. May 2024
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    Ataxia-Telangiectasia Mutated Loss-of-Function Displays Variant and Tissue-Specific Differences across Tumor Types
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    Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size
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  32. Feb 2024
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    HERC3 E3 ligase provides an ERAD branch eliminating select membrane proteins
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    Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition
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  35. Dec 2023
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    Mutational impact of APOBEC3A and APOBEC3B in a human cell line and comparisons to breast cancer
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  37. Aug 2023
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    Inhibition of acid sphingomyelinase reduces reactive astrocyte secretion of mitotoxic extracellular vesicles and improves Alzheimer’s disease pathology in the 5xFAD mouse
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  39. Jul 2023
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Obesity during preclinical Alzheimer's disease development exacerbates brain metabolic decline
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  41. Mar 2023
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    Functional hierarchy among different Rab27 effectors involved in secretory granule exocytosis
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  43. Jan 2023
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    Brain-derived neurotrophic factor (BDNF) induces antagonistic action to Nogo signaling by the upregulation of lateral olfactory tract usher substance (LOTUS) expression
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  45. Dec 2022
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    Critical roles for ‘housekeeping’ nucleases in type III CRISPR-Cas immunity
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    LOTUS suppresses amyloid β-induced dendritic spine elimination through the blockade of amyloid β binding to PirB
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  48. Nov 2022
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    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  51. Oct 2022
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering the mechanisms of transcription elongation by eukaryotic RNA polymerases I, II, and III
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  54. Jun 2022
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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    A naturally DNase-free CRISPR-Cas12c enzyme silences gene expression
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  57. May 2022
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    Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding
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  59. Apr 2022
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    A unique mode of nucleic acid immunity performed by a multifunctional bacterial enzyme
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  61. Mar 2022
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    Cardiomyocyte substructure reverts to an immature phenotype during heart failure
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    The anti-diabetic drug metformin regulates voltage-gated sodium channel NaV1.7 via the ubiquitin-ligase NEDD4-2
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  64. Jan 2022
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    Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
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  66. Oct 2021
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    Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
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    SUMOylation contributes to proteostasis of the chloroplast protein import receptor TOC159 during early development
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  69. Aug 2021
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    COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis
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    Reconstitution of the destruction complex defines roles of AXIN polymers and APC in β-catenin capture, phosphorylation, and ubiquitylation
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  74. Jul 2021
  75. www.mdpi.com www.mdpi.com
    Recruitment of DNA Repair MRN Complex by Intrinsically Disordered Protein Domain Fused to Cas9 Improves Efficiency of CRISPR-Mediated Genome Editing
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    Parkin‐mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes
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    Natural changes in light interact with circadian regulation at promoters to control gene expression in cyanobacteria
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    Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling
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    Two Separation-of-Function Isoforms of Human TPP1 Dictate Telomerase Regulation in Somatic and Germ Cells
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    Protein Kinase C Lambda Mediates Acid-Sensing Ion Channel 1a-Dependent Cortical Synaptic Plasticity and Pain Hypersensitivity
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    Translation attenuation by minocycline enhances longevity and proteostasis in old post-stress-responsive organisms
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    Unexpected sequences and structures of mtDNA required for efficient transcription from the first heavy-strand promoter
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    Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria
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    COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis
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    The Exon Junction Complex Undergoes a Compositional Switch that Alters mRNP Structure and Nonsense-Mediated mRNA Decay Activity
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    A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants
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  95. May 2021
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    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
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    Post-transcriptional repression of circadian component CLOCK regulates cancer-stemness in murine breast cancer cells
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    Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon
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    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
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  101. Feb 2021
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    Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15013
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    Homogentisic acid affects human osteoblastic functionality by oxidative stress and alteration of the Wnt/β‐catenin signaling pathway
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  104. Jan 2021
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ecd promotes U5 snRNP maturation and Prp8 stability
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    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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    Isoform-specific roles for AKT in affective behavior, spatial memory, and extinction related to psychiatric disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC7787664/
  108. Dec 2020
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    The Halastavi árva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism
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    CKIP-1 acts downstream to Cx43 on the activation of Nrf2 signaling pathway to protect from renal fibrosis in diabetes
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  111. Oct 2020
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    TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity
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    Eater cooperates with Multiplexin to drive the formation of hematopoietic compartments
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  114. Sep 2020
  115. journals.plos.org journals.plos.org
    Phosphorylation of mouse intestinal basolateral amino acid uniporter LAT4 is controlled by food-entrained diurnal rhythm and dietary proteins
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  116. elifesciences.org elifesciences.org
    Mechanisms of nucleotide selection by telomerase
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    Srsf10 and the minor spliceosome control tissue-specific and dynamic SR protein expression
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    Pre-emptive Quality Control of a Misfolded Membrane Protein by Ribosome-Driven Effects
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    CRISPR-Cas12a exploits R-loop asymmetry to form double-strand breaks
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