121 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline-like TCR-α chains shared between autoreactive T cells in blood and pancreas
    2
    1. scibot 22 Jun 2024
      RRID:SCR_014641

      DOI: 10.1038/s41467-024-48833-w

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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    2. scibot 22 Jun 2024
      RRID:SCR_01464118

      DOI: 10.1038/s41467-024-48833-w

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @evieth

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      RRIDCUR:Unresolved DOI:10.1038/s41467-024-48833-w RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC11176301/
  3. diabetesjournals.org diabetesjournals.org
    Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity
    1
    1. scibot 06 Jun 2024
      nPOD

      DOI: 10.2337/db23-0009

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @bandrow

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641 DOI:10.2337/db23-0009
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    diabetesjournals.org/diabetes/article/doi/10.2337/db23-0009/153726/Exocrine-pancreas-in-type-1-and-type-2-diabetes
  4. www.sciencedirect.com www.sciencedirect.com
    Extensive elimination of acinar cells during normal postnatal pancreas growth
    1
    1. scibot 06 Jun 2024
      nPODhttp://www.jdrfnpod.org/for-partners/npod-partners/

      DOI: 10.1016/j.celrep.2023.113457

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @bandrow

      SciCrunch record: RRID:SCR_014641

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      DOI:10.1016/j.celrep.2023.113457 RRID:SCR_014641
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    sciencedirect.com/science/article/pii/S2211124723014699
  5. www.nature.com www.nature.com
    The immunology of type 1 diabetes
    1
    1. scibot 06 Jun 2024
      nPOD; www.jdrfnpod.org

      DOI: 10.1038/s41577-023-00985-4

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @bandrow

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      RRID:SCR_014641 DOI:10.1038/s41577-023-00985-4
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    nature.com/articles/s41577-023-00985-4
  6. www.jove.com www.jove.com
    Advancing Type 1 Diabetes Research Using Innovative Pancreatic Slice Platforms
    2
    1. scibot 06 Jun 2024
      RRID:SCR_014641

      DOI: 10.3791/66468

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
    2. scibot 06 Jun 2024
      RRID:SCR_014641

      DOI: 10.3791/66468

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    jove.com/v/66468/advancing-type-1-diabetes-research-using-innovative-pancreatic-slice
  7. www.biorxiv.org www.biorxiv.org
    Immune perturbations in human pancreas lymphatic tissues prior to and after type 1 diabetes onset
    1
    1. scibot 06 Jun 2024
      RRID:SCR_014641

      DOI: 10.1101/2024.04.23.590798

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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      RRID:SCR_014641
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    biorxiv.org/content/10.1101/2024.04.23.590798v1
  8. link.springer.com link.springer.com
    Capillary contact points determine beta cell polarity, control secretion and are disrupted in the db/db mouse model of diabetes
    1
    1. scibot 05 Jun 2024
      RRID:SCR_014641

      DOI: 10.1007/s00125-024-06180-x

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
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    link.springer.com/article/10.1007/s00125-024-06180-x
  9. May 2024
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NKX2-2 based nuclei sorting on frozen human archival pancreas enables the enrichment of islet endocrine populations for single-nucleus RNA sequencing
    1
    1. scibot 02 May 2024
      RRID:SCR_014641

      DOI: 10.1186/s12864-024-10335-w

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059690/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence of human pancreatic beta cells enhances functional maturation through chromatin reorganization and promotes interferon responsiveness
    1
    1. scibot 02 May 2024
      RRID:SCR_014641

      DOI: 10.1093/nar/gkae313

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC11194086/
  12. Mar 2024
  13. dx.doi.org dx.doi.org
    DNA methylation-based assessment of cell composition in human pancreas and islets
    1
    1. scibot 30 Mar 2024
      RRID:SCR_014641

      DOI: 10.2337/db23-0704

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    dx.doi.org/10.2337/db23-0704
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8+ T cell responses
    1
    1. scibot 09 Mar 2024
      RRID:SCR_014641

      DOI: 10.1126/sciadv.adl1122

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10917340/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repositioning the Early Pathology of Type 1 Diabetes to the Extraislet Vasculature
    1
    1. scibot 08 Mar 2024
      RRID:SCR_014641

      DOI: 10.4049/jimmunol.2300769

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10944819/
  16. Feb 2024
  17. dx.doi.org dx.doi.org
    Bridging the Gap: Pancreas Tissue Slices From Organ and Tissue Donors for the Study of Diabetes Pathogenesis
    2
    1. scibot 16 Feb 2024
      RRID:SCR_014641

      DOI: 10.2337/dbi20-0018

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
    2. scibot 16 Feb 2024
      RRID:SCR_014641

      DOI: 10.2337/dbi20-0018

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    dx.doi.org/10.2337/dbi20-0018
  18. www.biorxiv.org www.biorxiv.org
    Impaired islet function with normal exocrine enzyme secretion is consistent across the head, body, and tail pancreas regions in type 1 diabetes
    1
    1. scibot 15 Feb 2024
      RRID:SCR_014641

      DOI: 10.1101/2024.02.08.579175

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    biorxiv.org/content/10.1101/2024.02.08.579175v1
  19. Jan 2024
  20. dx.doi.org dx.doi.org
    Bridging the Gap: Pancreas Tissue Slices From Organ and Tissue Donors for the Study of Diabetes Pathogenesis
    1
    1. scibot 18 Jan 2024
      RRID:SCR_014641

      DOI: 10.2337/dbi20-0018

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    dx.doi.org/10.2337/dbi20-0018
  21. Nov 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enteroviral infections are not associated with type 2 diabetes
    1
    1. scibot 16 Nov 2023
      SCR_014641

      DOI: 10.3389/fendo.2023.1236574

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10643152/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-reactive germline-like TCR alpha chains shared between blood and pancreas
    1
    1. scibot 09 Nov 2023
      RRID:SCR_014641

      DOI: 10.21203/rs.3.rs-3446917/v1

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10602137/
  24. Oct 2023
  25. www.sciencedirect.com www.sciencedirect.com
    Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage
    1
    1. scibot 28 Oct 2023
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2023.10.001

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    sciencedirect.com/science/article/pii/S1550413123003704
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The role of the interferon/JAK-STAT axis in driving islet HLA-I hyperexpression in type 1 diabetes
    1
    1. scibot 25 Oct 2023
      RRID:SCR_014641

      DOI: 10.3389/fendo.2023.1270325

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10588626/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interferon-α promotes neo-antigen formation and preferential HLA-B-restricted antigen presentation in pancreatic β-cells
    1
    1. scibot 05 Oct 2023
      RRID:SCR_014641

      DOI: 10.1101/2023.09.15.557918

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10516036/
  28. Sep 2023
  29. www.sciencedirect.com www.sciencedirect.com
    The pathogenic “symphony” in type 1 diabetes: A disorder of the immune system, β cells, and exocrine pancreas
    1
    1. scibot 27 Sep 2023
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2023.06.018

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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      RRID:SCR_014641
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    sciencedirect.com/science/article/pii/S1550413123002280
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Nano-Targeted Delivery of Immune Therapeutics in type 1 Diabetes
    1
    1. scibot 19 Sep 2023
      RRID:SCR_014641

      DOI: 10.1002/adma.202300812

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    onlinelibrary.wiley.com/doi/10.1002/adma.202300812
  31. Aug 2023
  32. www.biorxiv.org www.biorxiv.org
    Coxsackievirus infection induces direct pancreatic β-cell killing but poor anti-viral CD8+ T-cell responses
    1
    1. scibot 28 Aug 2023
      RRID:SCR_014641

      DOI: 10.1101/2023.08.19.553954

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    biorxiv.org/content/10.1101/2023.08.19.553954v1
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha cell receptor for advanced glycation end products associate with glucagon expression in type 1 diabetes
    1
    1. scibot 12 Aug 2023
      RRID:SCR_014641

      DOI: 10.1038/s41598-023-39243-x

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10412557/
  34. www.biorxiv.org www.biorxiv.org
    m6A mRNA Methylation Regulates Early Pancreatic β-Cell Differentiation
    1
    1. scibot 12 Aug 2023
      RRID:SCR_014641

      DOI: 10.1101/2023.08.03.551675

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
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    biorxiv.org/content/10.1101/2023.08.03.551675v1
  35. Jul 2023
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β Cell microRNAs Function as Molecular Hubs of Type 1 Diabetes Pathogenesis and as Biomarkers of Diabetes Risk
    1
    1. scibot 07 Jul 2023
      RRID:SCR_014641

      DOI: 10.1101/2023.06.15.545170

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
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    ncbi.nlm.nih.gov/pmc/articles/PMC10312758/
  37. Jun 2023
  38. www.sciencedirect.com www.sciencedirect.com
    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
    1
    1. scibot 21 Jun 2023
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2023.05.007

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    sciencedirect.com/science/article/pii/S1550413123001845
  39. rupress.org rupress.org
    Identification of an anergic BND cell-derived activated B cell population (BND2) in young-onset type 1 diabetes patients
    1
    1. scibot 16 Jun 2023
      RRID:SCR_014641

      DOI: 10.1084/jem.20221604

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
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    rupress.org/jem/article/220/8/e20221604/214110/Identification-of-an-anergic-BND-cell-derived
  40. May 2023
  41. www.nature.com www.nature.com
    A genomic data archive from the Network for Pancreatic Organ donors with Diabetes
    1
    1. scibot 28 May 2023
      RRID:SCR_014641

      DOI: 10.1038/s41597-023-02244-6

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

      SciCrunch record: RRID:SCR_014641

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      RRID:SCR_014641
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    nature.com/articles/s41597-023-02244-6
  42. Mar 2023
  43. europepmc.org europepmc.org
    The Extra-Islet Pancreas Supports Autoimmunity in Human Type 1 Diabetes
    1
    1. scibot 22 Mar 2023
      RRID:SCR_014641

      DOI: 10.1101/2023.03.15.23287145

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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    europepmc.org/article/ppr/ppr632531
  44. link.springer.com link.springer.com
    The extent and magnitude of islet T cell infiltration as powerful tools to define the progression to type 1 diabetes
    1
    1. scibot 14 Mar 2023
      RRID:SCR_014641

      DOI: 10.1007/s00125-023-05888-6

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    link.springer.com/article/10.1007/s00125-023-05888-6
  45. link.springer.com link.springer.com
    Presence of immunogenic alternatively spliced insulin gene product in human pancreatic delta cells
    1
    1. scibot 14 Mar 2023
      RRID:SCR_014641

      DOI: 10.1007/s00125-023-05882-y

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    link.springer.com/article/10.1007/s00125-023-05882-y
  46. Jan 2023
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of Proinflammatory Cytokines on Alternative Splicing Patterns in Human Islets
    1
    1. scibot 06 Jan 2023
      RRID:SCR_014641

      DOI: 10.2337/db20-0847

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8763875/
  48. Dec 2022
  49. 52.53.155.43 52.53.155.43
    Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes
    1
    1. scibot 09 Dec 2022
      RRID:SCR_014641

      DOI: 10.2337/db22-0191

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    52.53.155.43/d86b44398b4d6d308da57b3903457c31e49a9f3c/db220191-html.html
  50. journals.sagepub.com journals.sagepub.com
    Abnormal Expression of an Insulin Synthesizing Enzyme in Islets of Adult Autoantibody Positive Donors
    4
    1. scibot 09 Dec 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @scibot

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      RRID:SCR_014641
    2. scibot 08 Dec 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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      RRID:SCR_014641
    3. scibot 02 Dec 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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      RRID:SCR_014641
    4. scibot 01 Dec 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    journals.sagepub.com/doi/full/10.1369/00221554221138368
  51. www.sciencedirect.com www.sciencedirect.com
    A discovery-based proteomics approach identifies protein disulphide isomerase (PDIA1) as a biomarker of β cell stress in type 1 diabetes
    1
    1. scibot 02 Dec 2022
      RRID:SCR_014641

      DOI: 10.1016/j.ebiom.2022.104379

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    sciencedirect.com/science/article/pii/S2352396422005618
  52. Nov 2022
  53. journals.sagepub.com journals.sagepub.com
    Abnormal Expression of an Insulin Synthesizing Enzyme in Islets of Adult Autoantibody Positive Donors
    6
    1. scibot 30 Nov 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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    2. scibot 22 Nov 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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    4. scibot 15 Nov 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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    5. scibot 10 Nov 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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    6. scibot 08 Nov 2022
      RRID:SCR_014641

      DOI: 10.1369/00221554221138368

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    journals.sagepub.com/doi/full/10.1369/00221554221138368
  54. www.nature.com www.nature.com
    Non-coding variants disrupting a tissue-specific regulatory element in HK1 cause congenital hyperinsulinism
    2
    1. scibot 08 Nov 2022
      RRID SCR_014641

      DOI: 10.1038/s41588-022-01204-x

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    2. scibot 08 Nov 2022
      RRID SCR_014641

      DOI: 10.1038/s41588-022-01204-x

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    nature.com/articles/s41588-022-01204-x
  55. Oct 2022
  56. link.springer.com link.springer.com
    Milder loss of insulin-containing islets in individuals with type 1 diabetes and type 2 diabetes-associated TCF7L2 genetic variants
    1
    1. scibot 27 Oct 2022
      RRID:SCR_014641

      DOI: 10.1007/s00125-022-05818-y

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    link.springer.com/article/10.1007/s00125-022-05818-y
  57. academic.oup.com academic.oup.com
    Exocrine and Endocrine Inflammation Increases Cellular Replication in the Pancreatic Duct Compartment in Type 1 Diabetes
    1
    1. scibot 26 Oct 2022
      RRID:SCR_014641

      DOI: 10.1210/jendso/bvac136

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    academic.oup.com/jes/article/6/11/bvac136/6691224
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alpha cell dysfunction in type 1 diabetes is independent of a senescence program
    1
    1. scibot 25 Oct 2022
      SCR_014641

      DOI: 10.3389/fendo.2022.932516

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    ncbi.nlm.nih.gov/pmc/articles/PMC9586489/
  59. Aug 2022
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Detection of Antiviral Tissue Responses and Increased Cell Stress in the Pancreatic Islets of Newly Diagnosed Type 1 Diabetes Patients: Results From the DiViD Study
    1
    1. scibot 13 Aug 2022
      SCR_014641

      DOI: 10.3389/fendo.2022.881997

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    ncbi.nlm.nih.gov/pmc/articles/PMC9360491/
  61. Jul 2022
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    High Prevalence of Common Human Viruses in Thyroid Tissue
    1
    1. scibot 31 Jul 2022
      RRID:SCR_014641

      DOI: 10.3389/fendo.2022.938633

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    ncbi.nlm.nih.gov/pmc/articles/PMC9333159/
  63. www.medrxiv.org www.medrxiv.org
    HLA-DQβ57, anti-insulin T cells and insulin mimicry in autoimmune diabetes
    1
    1. scibot 15 Jul 2022
      RRID:SCR_014641

      DOI: 10.1101/2022.05.11.22274678

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    medrxiv.org/content/10.1101/2022.05.11.22274678v1
  64. www.medrxiv.org www.medrxiv.org
    A novel disease mechanism leading to the expression of a disallowed gene in the pancreatic beta-cell identified by non-coding, regulatory mutations controlling HK1
    1
    1. scibot 15 Jul 2022
      RRID:SCR_014641

      DOI: 10.1101/2021.12.03.21267240

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    medrxiv.org/content/10.1101/2021.12.03.21267240v1
  65. Jun 2022
  66. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      DOI: 10.1002/1873-3468.14411

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    febs.onlinelibrary.wiley.com/doi/10.1002/1873-3468.14411
  67. diabetesjournals.org diabetesjournals.org
    Circulating C-Peptide Levels in Living Children and Young People and Pancreatic Beta Cell Loss in Pancreas Donors Across Type 1 Diabetes Disease Duration
    1
    1. scibot 25 Jun 2022
      RRID:SCR_014641

      DOI: 10.2337/db22-0097

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    diabetesjournals.org/diabetes/article/71/7/1591/146866/Circulating-C-Peptide-Levels-in-Living-Children
  68. Apr 2022
  69. www.nature.com www.nature.com
    Generation of human islet cell type-specific identity genesets
    1
    1. scibot 23 Apr 2022
      RRID:SCR_014641

      DOI: 10.1038/s41467-022-29588-8

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    nature.com/articles/s41467-022-29588-8
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Observing Islet Function and Islet-Immune Cell Interactions in Live Pancreatic Tissue Slices
    1
    1. scibot 13 Apr 2022
      RRID:SCR_014641

      DOI: 10.3791/62207

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    ncbi.nlm.nih.gov/pmc/articles/PMC8314551/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evidence of islet CADM1-mediated immune cell interactions during human type 1 diabetes
    1
    1. scibot 09 Apr 2022
      RRID:SCR_014641

      DOI: 10.1172/jci.insight.153136

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    ncbi.nlm.nih.gov/pmc/articles/PMC8986082/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MERTK on mononuclear phagocytes regulates T cell antigen recognition at autoimmune and tumor sites
    1
    1. scibot 05 Apr 2022
      RRID:SCR_014641

      DOI: 10.1084/jem.20200464

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    ncbi.nlm.nih.gov/pmc/articles/PMC8383814/
  73. Jan 2022
  74. diabetesjournals.org diabetesjournals.org
    Syntaxin 4 enrichment in β-cells prevents conversion to autoimmune diabetes in non-obese diabetic (NOD) mice
    1
    1. scibot 28 Jan 2022
      RRID:SCR_014641

      DOI: 10.2337/db21-0170

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    diabetesjournals.org/diabetes/article/70/12/2837/139076/Syntaxin-4-Enrichment-in-Cells-Prevents-Conversion
  75. Dec 2021
  76. diabetesjournals.org diabetesjournals.org
    CD8+ T cells variably recognize native versus citrullinated GRP78 epitopes in type 1 diabetes
    1
    1. scibot 23 Dec 2021
      RRID:SCR_014641

      DOI: 10.2337/db21-0259

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    diabetesjournals.org/diabetes/article/70/12/2879/139067/CD8-T-Cells-Variably-Recognize-Native-Versus
  77. link.springer.com link.springer.com
    Upregulation of HLA class II in pancreatic beta cells from organ donors with type 1 diabetes
    1
    1. scibot 22 Dec 2021
      RRID:SCR_014641

      DOI: 10.1007/s00125-021-05619-9

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    link.springer.com/article/10.1007/s00125-021-05619-9
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Substance Use Affects Type 1 Diabetes Pancreas Pathology: Implications for Future Studies
    1
    1. scibot 15 Dec 2021
      SCR_014641

      DOI: 10.3389/fendo.2021.778912

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8667172/
  79. insight.jci.org insight.jci.org
    Autoreactive T cell receptors with shared germline-like α chains in type 1 diabetes
    1
    1. scibot 03 Dec 2021
      RRID:SCR_014641

      DOI: 10.1172/jci.insight.151349

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    insight.jci.org/articles/view/151349
  80. Nov 2021
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Editorial: Footprints of Immune Cells in the Type 1 Diabetic Pancreas
    1
    1. scibot 05 Nov 2021
      SCR_014641

      DOI: 10.3389/fendo.2021.767012

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC8551857/
  82. www.sciencedirect.com www.sciencedirect.com
    Single-cell analysis of the human pancreas in type 2 diabetes using multi-spectral imaging mass cytometry
    1
    1. scibot 03 Nov 2021
      RRID:SCR_014641

      DOI: 10.1016/j.celrep.2021.109919

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    sciencedirect.com/science/article/pii/S2211124721013929
  83. Oct 2021
  84. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Reduced Follicular Regulatory T Cells in Spleen and Pancreatic Lymph Nodes of Patients With Type 1 Diabetes
    1
    1. scibot 18 Oct 2021
      Fousteri

      DOI: 10.2337/db21-0091

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    diabetes.diabetesjournals.org/content/early/2021/10/06/db21-0091
  85. www.pnas.org www.pnas.org
    Human islet T cells are highly reactive to preproinsulin in type 1 diabetes
    1
    1. scibot 16 Oct 2021
      RRID:SCR_014641

      DOI: 10.1073/pnas.2107208118

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    pnas.org/content/118/41/e2107208118
  86. academic.oup.com academic.oup.com
    Human Islet: Mini-organ with Mega-impact
    1
    1. scibot 01 Oct 2021
      RRID:SCR_014641

      DOI: 10.1210/endrev/bnab010

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    academic.oup.com/edrv/article/42/5/605/6223906
  87. Aug 2021
  88. www.nature.com www.nature.com
    Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production
    1
    1. scibot 14 Aug 2021
      RRID:SCR_014641

      DOI: 10.1038/s41467-021-24788-0

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    nature.com/articles/s41467-021-24788-0
  89. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 06 Aug 2021
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2018.10.007

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    sciencedirect.com/science/article/pii/S1550413118306399
  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
    1
    1. scibot 05 Aug 2021
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2018.04.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
  91. www.sciencedirect.com www.sciencedirect.com
    IL-17 is expressed on beta and alpha cells of donors with type 1 and type 2 diabetes
    1
    1. scibot 05 Aug 2021
      RRID:SCR_014641

      DOI: 10.1016/j.jaut.2021.102708

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    sciencedirect.com/science/article/pii/S0896841121001165
  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NKG2D Signaling Within the Pancreatic Islets Reduces NOD Diabetes and Increases Protective Central Memory CD8+ T-Cell Numbers
    1
    1. scibot 04 Aug 2021
      RRID:SCR_014641

      DOI: 10.2337/db19-0979

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    ncbi.nlm.nih.gov/pmc/articles/PMC7372071/
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
      RRID:SCR_014641

      DOI: 10.1016/j.coph.2018.07.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC6294842/
  94. Jul 2021
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 31 Jul 2021
      RRID:SCR_014641

      DOI: 10.1007/s00125-018-4731-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC6223849/
  96. www.sciencedirect.com www.sciencedirect.com
    ACE2 Chromogenic Immunostaining Protocol Optimized for Formalin-fixed Paraffin Embedded Human Tissue Sections
    1
    1. scibot 30 Jul 2021
      RRID:SCR_014641

      DOI: 10.1016/j.xpro.2021.100696

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    sciencedirect.com/science/article/pii/S2666166721004032
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Means, Motive, and Opportunity: Do Non-Islet-Reactive Infiltrating T Cells Contribute to Autoimmunity in Type 1 Diabetes?
    1
    1. scibot 03 Jul 2021
      SCR_014641

      DOI: 10.3389/fimmu.2021.683091

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    ncbi.nlm.nih.gov/pmc/articles/PMC8242234/
  98. Jun 2021
  99. papers.ssrn.com papers.ssrn.com
    ACE2 and SARS-CoV-2 Expression in the Normal and COVID-19 Pancreas
    1
    1. scibot 26 Jun 2021
      RRID:SCR_014641

      DOI: 10.2139/ssrn.3691242

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    papers.ssrn.com/sol3/papers.cfm
  100. www.frontiersin.org www.frontiersin.org
    Whole-Slide Image Analysis of Human Pancreas Samples to Elucidate the Immunopathogenesis of Type 1 Diabetes Using the QuPath Software
    1
    1. scibot 24 Jun 2021
      RRID:SCR_014641

      DOI: 10.3389/fmolb.2021.689799

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    frontiersin.org/article/10.3389/fmolb.2021.689799/full
  101. May 2021
  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    State‐of‐the‐art microscopy to understand Islets of Langerhans: what to expect next?
    1
    1. scibot 13 May 2021
      RRID:SCR_014641

      DOI: 10.1111/imcb.12450

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    onlinelibrary.wiley.com/doi/10.1111/imcb.12450
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreas Optical Clearing and 3-D Microscopy in Health and Diabetes
    1
    1. scibot 12 May 2021
      SCR_014641

      DOI: 10.3389/fendo.2021.644826

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    ncbi.nlm.nih.gov/pmc/articles/PMC8108133/
  104. journals.sagepub.com journals.sagepub.com
    Human Islets Contain a Beta Cell Type That Expresses Proinsulin But Not the Enzyme That Converts the Precursor to Insulin - Gladys Teitelman, 2020
    1
    1. scibot 10 May 2021
      RRID:SCR_014641

      DOI: 10.1369/0022155420961361

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    journals.sagepub.com/doi/10.1369/0022155420961361
  105. link.springer.com link.springer.com
    Identification and characterisation of tertiary lymphoid organs in human type 1 diabetes
    1
    1. scibot 04 May 2021
      RRID:SCR_014641

      DOI: 10.1007/s00125-021-05453-z

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    link.springer.com/article/10.1007/s00125-021-05453-z
  106. Apr 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proinsulin-Reactive CD4 T Cells in the Islets of Type 1 Diabetes Organ Donors
    1
    1. scibot 10 Apr 2021
      RRID:SCR_014641

      DOI: 10.3389/fendo.2021.622647

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    ncbi.nlm.nih.gov/pmc/articles/PMC8027116/
  108. Mar 2021
  109. www.nature.com www.nature.com
    Islet sympathetic innervation and islet neuropathology in patients with type 1 diabetes
    1
    1. scibot 28 Mar 2021
      RRID:SCR_014641

      DOI: 10.1038/s41598-021-85659-8

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    nature.com/articles/s41598-021-85659-8
  110. www.sciencedirect.com www.sciencedirect.com
    TCR+/BCR+ dual-expressing cells and their associated public BCR clonotype are not enriched in type 1 diabetes
    1
    1. scibot 22 Mar 2021
      RRID:SCR_014641

      DOI: 10.1016/j.cell.2020.11.035

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    sciencedirect.com/science/article/pii/S009286742031607X
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Islet expression of type I interferon response sensors is associated with immune infiltration and viral infection in type 1 diabetes
    1
    1. scibot 13 Mar 2021
      RRID:SCR_014641

      DOI: 10.1126/sciadv.abd6527

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    ncbi.nlm.nih.gov/pmc/articles/PMC7904254/
  112. Feb 2021
  113. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    Intracrine Testosterone Activation in Human Pancreatic β Cells Stimulates Insulin Secretion.
    1
    1. scibot 26 Feb 2021
      RRID:SCR_014641

      DOI: 10.2337/db20-0228

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    diabetes.diabetesjournals.org/content/69/11/2392
  114. insight.jci.org insight.jci.org
    Pancreas tissue slices from organ donors enable in situ analysis of type 1 diabetes pathogenesis
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    1. scibot 25 Feb 2021
      RRID:SCR_014641

      DOI: 10.1172/jci.insight.134525

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    insight.jci.org/articles/view/134525
  115. link.springer.com link.springer.com
    Pancreatic beta cell autophagy is impaired in type 1 diabetes
    1
    1. scibot 24 Feb 2021
      RRID:SCR_014641

      DOI: 10.1007/s00125-021-05387-6

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    link.springer.com/article/10.1007/s00125-021-05387-6
  116. Jan 2021
  117. link.springer.com link.springer.com
    Expression of immunoreactive inducible nitric oxide synthase in pancreatic islet cells from newly diagnosed and long-term type 1 diabetic donors is heterogeneous and not disease-associated
    1
    1. scibot 20 Jan 2021
      RRID:SCR_014641

      DOI: 10.1007/s00441-020-03340-4

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    link.springer.com/article/10.1007/s00441-020-03340-4
  118. www.frontiersin.org www.frontiersin.org
    Gene Expression Analysis of the Pre-Diabetic Pancreas to Identify Pathogenic Mechanisms and Biomarkers of Type 1 Diabetes
    1
    1. scibot 07 Jan 2021
      RRID:SCR_014641

      DOI: 10.3389/fendo.2020.609271

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    frontiersin.org/article/10.3389/fendo.2020.609271/full
  119. link.springer.com link.springer.com
    Structural and functional polarisation of human pancreatic beta cells in islets from organ donors with and without type 2 diabetes
    1
    1. scibot 06 Jan 2021
      RRID:SCR_014641

      DOI: 10.1007/s00125-020-05345-8

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    link.springer.com/article/10.1007/s00125-020-05345-8
  120. Dec 2020
  121. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Removing Formaldehyde‐Induced Peptidyl Crosslinks Enables Mass Spectrometry Imaging of Peptide Hormone Distributions from Formalin‐Fixed Paraffin‐Embedded Tissues
    1
    1. scibot 07 Dec 2020
      RRID:SCR_014641

      DOI: 10.1002/anie.202008847

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    onlinelibrary.wiley.com/doi/10.1002/anie.202008847
  122. Nov 2020
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of SARS-CoV-2 Entry Factors in the Pancreas of Normal Organ Donors and Individuals with COVID-19
    1
    1. scibot 24 Nov 2020
      RRID:SCR_014641

      DOI: 10.1016/j.cmet.2020.11.005

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7664515/
  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-4R is expressed on alpha and beta cells of human pancreata
    1
    1. scibot 21 Nov 2020
      RRID:SCR_014641

      DOI: 10.1016/j.clim.2020.108394

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7673200/
  125. Oct 2020
  126. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Presumption of guilt for T cells in type 1 diabetes: lead culprits or partners in crime depending on age of onset?
    1
    1. scibot 24 Oct 2020
      RRID:SCR_014641

      DOI: 10.1007/s00125-020-05298-y

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    pubmed.ncbi.nlm.nih.gov/33084970/
  127. Sep 2020
  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Erratum. GLP-1 Receptor in Pancreatic α-Cells Regulates Glucagon Secretion in a Glucose-Dependent Bidirectional Manner. Diabetes 2019;68:34–44
    1
    1. scibot 16 Sep 2020
      RRID:SCR_014641

      DOI: 10.2337/db20-er02c

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    ncbi.nlm.nih.gov/pmc/articles/PMC7118249/
  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypusinated eIF5A is expressed in the pancreas and spleen of individuals with type 1 and type 2 diabetes
    1
    1. scibot 16 Sep 2020
      RRID:SCR_014641

      DOI: 10.1371/journal.pone.0230627

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7092972/
  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term culture of human pancreatic slices as a model to study real-time islet regeneration
    1
    1. scibot 15 Sep 2020
      RRID:SCR_014641

      DOI: 10.1038/s41467-020-17040-8

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7324563/
  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Organisation of the human pancreas in health and in diabetes
    1
    1. scibot 10 Sep 2020
      RRID:SCR_014641

      DOI: 10.1007/s00125-020-05203-7

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7565096/
  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale electron microscopy database for human type 1 diabetes
    1
    1. scibot 08 Sep 2020
      RRID:SCR_014641

      DOI: 10.1038/s41467-020-16287-5

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    ncbi.nlm.nih.gov/pmc/articles/PMC7235089/
  133. www.pnas.org www.pnas.org
    Single-cell resolution analysis of the human pancreatic ductal progenitor cell niche
    1
    1. scibot 06 Sep 2020
      RRID:SCR_014641

      DOI: 10.1073/pnas.1918314117

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    pnas.org/content/early/2020/04/29/1918314117
  134. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Histological validation of a type 1 diabetes clinical diagnostic model for classification of diabetes
    1
    1. scibot 03 Sep 2020
      RRID:SCR_014641

      DOI: 10.1111/dme.14361

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    onlinelibrary.wiley.com/doi/10.1111/dme.14361
  135. Jan 2020
  136. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell
    1
    1. scibot 13 Jan 2020
      RRID:SCR_014641

      DOI: 10.1038/s42255-019-0135-7

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    pubmed.ncbi.nlm.nih.gov/32432213/
  137. diabetes.diabetesjournals.org diabetes.diabetesjournals.org
    HLA Class II Antigen Processing and Presentation Pathway Components Demonstrated by Transcriptome and Protein Analyses of Islet β-Cells From Donors With Type 1 Diabetes
    1
    1. scibot 13 Jan 2020
      SCR_014641

      DOI: 10.2337/db18-0686

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

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    diabetes.diabetesjournals.org/content/68/5/988
  138. link.springer.com link.springer.com
    Phenotypic alterations in pancreatic lymph node stromal cells from human donors with type 1 diabetes and NOD mice
    1
    1. scibot 13 Jan 2020
      RRID:SCR_014641

      DOI: 10.1007/s00125-019-04984-w

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    link.springer.com/article/10.1007/s00125-019-04984-w
  139. academic.oup.com academic.oup.com
    Cellular stressors may alter islet hormone cell proportions by moderation of alternative splicing patterns
    1
    1. scibot 13 Jan 2020
      RRID:SCR_014641

      DOI: 10.1093/hmg/ddz094

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    academic.oup.com/hmg/article/28/16/2763/5487670
  140. www.sciencedirect.com www.sciencedirect.com
    IL-6 is present in beta and alpha cells in human pancreatic islets: Expression is reduced in subjects with type 1 diabetes
    1
    1. scibot 13 Jan 2020
      RRID:SCR_014641

      DOI: 10.1016/j.clim.2019.108320

      Resource: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641)

      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1521661619304796
  141. link.springer.com link.springer.com
    Untitled document
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      RRID:SCR_014641

      DOI: 10.1007/s00125-019-4822-4

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  142. academic.oup.com academic.oup.com
    Untitled document
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      RRID:SCR_014641

      DOI: 10.1093/hmg/ddz094

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz094/5487670
  143. Nov 2018
  144. link.springer.com link.springer.com
    Untitled document
    1
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    link.springer.com/article/10.1007/s00125-018-4731-y
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6237216/
  146. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1471489217302205
  147. link.springer.com link.springer.com
    Untitled document
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    link.springer.com/article/10.1007/s00125-018-4704-1
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes
    1
    1. scibot 05 Nov 2018
      RRID:SCR_014641

      Curator: @evieth

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    ncbi.nlm.nih.gov/pmc/articles/PMC5989056/