68 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Living Multi‐Omics PDX Biobank of High‐Risk Sarcomas Reveals ecDNA‐Driven Oncogene Amplification in Osteosarcoma and Enables Preclinical Precision Oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC13658889/
  3. Oct 2026
  4. www.nature.com www.nature.com
    Switches in alternatively spliced isoforms impact protein and drug interactions in melanoma, ovarian cancer, and acute myeloid leukemia
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    nature.com/articles/s41416-026-03638-0
  5. Sep 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Efficacy and Genomic Analysis of HER2-Mutant Metastatic Triple-Negative Breast Cancer Treated with Neratinib Alone or with Trastuzumab in the SUMMIT Basket Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530984/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical and Pathologic Landscape of DLL3 and SEZ6 Expression in Neuroendocrine Carcinomas
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    pmc.ncbi.nlm.nih.gov/articles/PMC13537436/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Landscape of Genomic and Socioeconomic Variables in Patients with Colorectal Cancer Based on Genetic Ancestry
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    pmc.ncbi.nlm.nih.gov/articles/PMC13530983/
  9. www.sciencedirect.com www.sciencedirect.com
    Integrated clinicogenomic analysis reveals the evolution and metastatic tropisms of advanced colorectal cancer
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    sciencedirect.com/science/article/pii/S1535610826003600
  10. Aug 2026
  11. 54.241.53.176 54.241.53.176
    ccr-25-4135-html.html
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  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HER2 heterogeneous breast cancer models reveal novel therapeutic targets and subclonal dynamics during evolution to resistance to HER2-targeted therapies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430225/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and Clinical Determinants of Targeted Therapy Treatment in Biliary Tract Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13420548/
  14. Jul 2026
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and immune landscape of recurrent and/or distant metastatic squamous cell carcinoma of the head and neck: an EORTC/IMMUCAN project
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    pmc.ncbi.nlm.nih.gov/articles/PMC13320198/
  16. Jun 2026
  17. aacrjournals.org aacrjournals.org
    Characterizing Longitudinal Molecular Changes in ctDNA in Patients with Metastatic Castration-resistant Prostate Cancer
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    aacrjournals.org/clincancerres/article/32/10/2060/785106/Characterizing-Longitudinal-Molecular-Changes-in
  18. aacrjournals.org aacrjournals.org
    PI3K inhibition in combination with tamoxifen in patients with metastatic HR+/HER2- breast cancer: clinical and circulating tumor DNA results
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    aacrjournals.org/clincancerres/article/32/10/1983/785105/PI3K-Inhibition-in-Combination-with-Tamoxifen-in
  19. aacrjournals.org aacrjournals.org
    Phase I/II study of the PARP inhibitor olaparib and irinotecan in children and young adults with recurrent/refractory malignancies: Arm D of the AcSé-ESMART trial
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    aacrjournals.org/clincancerres/article/32/7/1210/775515/Phase-I-II-Study-of-the-PARP-Inhibitor-Olaparib
  20. aacrjournals.org aacrjournals.org
    The Impact of Concordance Between Liquid and Tissue Biopsy for Actionable Mutations: Insights from the Rome Trial
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    aacrjournals.org/clincancerres/article/32/1/45/771258/The-Impact-of-Concordance-between-Liquid-and
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    Evolution of AR and non-AR alterations in circulating tumor DNA of metastatic prostate cancer patients treated in the phase 3 Alliance A031201 trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC13266347/
  22. May 2026
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Contrasting Features of Papillary and Chromophobe Renal Cell Carcinoma Revealed by Whole-Genome Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136883/
  24. Apr 2026
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Gastric epithelium from BRCA1 and BRCA2 carriers harbors increased double-stranded DNA damage and enhanced growth potential
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    pmc.ncbi.nlm.nih.gov/articles/PMC13110856/
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor genomics in patients younger than 40 years of age with metastatic breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13057355/
  27. Mar 2026
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neoadjuvant nivolumab with or without ipilimumab for cisplatin-ineligible patients with muscle-invasive bladder cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12967298/
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Precision Oncology for Pediatric Solid Tumors Using In‐Hospital Pediatric/AYA Malignancy‐Specific Panel Sequencing
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    pmc.ncbi.nlm.nih.gov/articles/PMC12951107/
  30. Feb 2026
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improving Global Access to Genomic Profiling in Rare Pediatric Cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC12233128/
  32. Jan 2026
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Knowledge Connector decision support system for multiomics-based precision oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC12820158/
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinicogenomic characterization of inflammatory breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12255483/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessment of Circulating Tumor DNA for Early Detection of Hepatocellular Carcinoma in Alpha‐Fetoprotein–Negative Patients With Cirrhotic Nodules
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    pmc.ncbi.nlm.nih.gov/articles/PMC12748524/
  36. Dec 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Radiogenomic Profiling of Prostate Tumors prior to External Beam Radiotherapy Converges on a Transcriptomic Signature of TGF-β Activity Driving Tumor Recurrence
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    pmc.ncbi.nlm.nih.gov/articles/PMC12703358/
  38. www.nature.com www.nature.com
    Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion
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    nature.com/articles/s41698-025-01190-3
  39. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PatientProfiler: building patient-specific signaling models from proteogenomic data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12672659/
  40. Oct 2025
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and Immune Landscape of Pancreatic Ductal Adenocarcinoma Associated with Germline Pathogenic Variants in ATM
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    pmc.ncbi.nlm.nih.gov/articles/PMC12500237/
  42. ascopubs.org ascopubs.org
    Clinical and Pathologic Landscapes of Delta-Like Ligand 3 and Seizure-Related Homolog Protein 6 Expression in Neuroendocrine Carcinomas
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    ascopubs.org/doi/10.1200/PO-25-00464
  43. www.sciencedirect.com www.sciencedirect.com
    CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1
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    sciencedirect.com/science/article/pii/S266637912500480X
  44. Sep 2025
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular characterization of NUT carcinoma: a report from the NUT carcinoma registry
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    pmc.ncbi.nlm.nih.gov/articles/PMC12373430/
  46. Jul 2025
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RIT1 Drives Oncogenic Transformation and is an Actionable Target in Lung Adenocarcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281470/
  48. ascopubs.org ascopubs.org
    Clinical Significance of TERT Promoter Mutations in Neuroblastoma
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    ascopubs.org/doi/10.1200/PO-25-00074
  49. Jun 2025
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cambridge Neoadjuvant Cancer of the Prostate (CANCAP03): A Window Study into the Effects of Olaparib ± Degarelix in Primary Prostate Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617790/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Spatial–Temporal Diversity of Extrachromosomal DNA Shapes Urothelial Carcinoma Evolution and the Tumor Immune Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12130809/
  52. May 2025
  53. 52.53.155.43 52.53.155.43
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  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Diverse ERBB2/ERBB3 Activating Alterations and Coalterations Have Implications for HER2/3-Targeted Therapies across Solid Tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12022956/
  55. Apr 2025
  56. aacrjournals.org aacrjournals.org
    Ancestral differences in anti-cancer treatment efficacy and their underlying genomic and molecular alterations
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    aacrjournals.org/cancerdiscovery/article/15/3/511/752115/Ancestral-Differences-in-Anticancer-Treatment
  57. Feb 2025
  58. 52.53.155.43 52.53.155.43
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  59. aacrjournals.org aacrjournals.org
    Transcriptional phenocopies of deleterious KEAP1 mutations correlate with survival outcomes in lung cancer treated with immunotherapy
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    aacrjournals.org/clincancerres/article/30/19/4397/748547/Transcriptional-Phenocopies-of-Deleterious-KEAP1
  60. Nov 2024
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Molecular and modular intricacies of precision oncology
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    pmc.ncbi.nlm.nih.gov/articles/PMC11537923/
  62. Oct 2024
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical value of liquid biopsy in FGFR2 fusion-positive cholangiocarcinoma patients during targeted therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443220/
  64. Sep 2024
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel ERBB2 Variant Potentially Associated with Resistance against Anti-HER2 Monoclonal Antibody–Based Therapy in ERBB2-Amplified Metastatic Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393546/
  66. aacrjournals.org aacrjournals.org
    Activating mTOR mutations are detrimental in nutrient-poor conditions
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    aacrjournals.org/cancerres/article/82/18/3263/709030/Activating-mTOR-Mutations-Are-Detrimental-in
  67. Aug 2024
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of rare structural variant events in newly diagnosed multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10841766/
  69. Jul 2024
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical and genomic landscape of FGFR3-altered urothelial carcinoma and treatment outcomes with erdafitinib: a real-world experience
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    ncbi.nlm.nih.gov/pmc/articles/PMC11233068/
  71. Jun 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early detection and diagnosis of cancer with interpretable machine learning to uncover cancer-specific DNA methylation patterns
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    ncbi.nlm.nih.gov/pmc/articles/PMC11186673/
  73. May 2024
  74. aacrjournals.org aacrjournals.org
    Integrative molecular analyses of the MD Anderson prostate cancer patient-derived xenograft (MDA PCa PDX) series
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    aacrjournals.org/clincancerres/article/30/10/2272/745168/Integrative-Molecular-Analyses-of-the-MD-Anderson
  75. aacrjournals.org aacrjournals.org
    Molecular and pathological characterization of YAP1-expressing small cell lung cancer cell lines leads to reclassification as SMARCA4-deficient malignancies
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    aacrjournals.org/clincancerres/article/30/9/1846/743134/Molecular-and-Pathologic-Characterization-of-YAP1
  76. Mar 2024
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10907580/
  78. Feb 2024
  79. 52.53.155.43 52.53.155.43
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  80. Nov 2023
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical and Molecular Features of Long-term Response to Immune Checkpoint Inhibitors in Patients with Advanced Non–Small Cell Lung Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10618656/
  82. Oct 2023
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic Biomarkers Associated with Response to Induction Chemotherapy in Patients with Localized Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073273/
  84. Sep 2023
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identifying mechanisms of resistance by circulating tumour DNA in EVOLVE, a Phase II Trial of Cediranib Plus Olaparib for Ovarian Cancer at time of PARP Inhibitor Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10502468/
  86. Aug 2023
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alterations in Somatic Driver Genes Are Associated with Response to Neoadjuvant FOLFIRINOX in Patients with Localized Pancreatic Ductal Adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9319357/
  88. Jun 2023
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Efficacy and Whole Exome Sequencing of Liquid Biopsies in a Phase IB/II study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9722539/
  90. Apr 2023
  91. link.springer.com link.springer.com
    Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways
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    link.springer.com/article/10.1038/s41598-023-33096-0
  92. Feb 2023
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9936149/
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic Stratification of Resectable Colorectal Liver Metastasis Patients and Implications for Adjuvant Therapy and Survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC8754193/
  95. Jan 2023
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human metastatic cholangiocarcinoma patient-derived xenografts and tumoroids for preclinical drug evaluation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9873249/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Phase II Trial of the Bruton Tyrosine-Kinase Inhibitor Zanubrutinib (BGB-3111) in Patients with Relapsed/Refractory Waldenström Macroglobulinemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC9401548/
  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic Essentiality of Tryptophan 2,3-dioxygenase 2 in APC-Mutated Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262860/
  99. Aug 2022
  100. 52.53.155.43 52.53.155.43
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  101. Jun 2022
  102. 52.53.155.43 52.53.155.43
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  103. Apr 2022
  104. aacrjournals.org aacrjournals.org
    FREQUENCY AND GENOMIC ASPECTS OF INTRINSIC RESISTANCE TO VISMODEGIB IN LOCALLY ADVANCED BASAL CELL CARCINOMA
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    aacrjournals.org/clincancerres/article/28/7/1422/682219/Frequency-and-Genomic-Aspects-of-Intrinsic
  105. Aug 2021
  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic characterization of de novo metastatic breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC7887078/
  107. Jan 2020
  108. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genomic stratification beyond Ras/B‐Raf in colorectal liver metastasis patients treated with hepatic arterial infusion
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    onlinelibrary.wiley.com/doi/10.1002/cam4.2415