152 Matching Annotations
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  2. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226009314-main-html.html
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  3. Mar 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    3D “emboli” culture models epithelial breast cancer cell oxidative mitochondrial metabolism with relevance for lung metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13012061/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dietary sulfur amino acid restriction elicits a cold-like transcriptional response in inguinal but not epididymal white adipose tissue of male mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12995289/
  6. www.biorxiv.org www.biorxiv.org
    Transcriptomic profiling of mouse mammary tumors enables prognostic and predictive biomarker discovery for human breast cancers
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    biorxiv.org/content/10.64898/2026.02.28.707759v1
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ex Vivo Immuno-Oncology Platform Reveals Spatial T Cell Infiltration Patterns Linked to ATR Inhibition Responses in High-Grade Serous Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618831/
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    DCPS modulates TDP-43-linked neurodegeneration through P-body-mediated RNA decay
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    sciencedirect.com/science/article/pii/S0896627326000449
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    OGDHL promotes prostate cancer progression and regulates neuroendocrine marker expression and nucleotide abundance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12949684/
  10. Feb 2026
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of CADM1 as an Immunotherapeutic Target and Evaluation of a Novel CADM1-Targeting Antibody-Drug Conjugate in Preclinical Osteosarcoma Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12925509/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Modelling EWS::FLI1 protein fluctuations reveal determinants of tumor plasticity in Ewing sarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905378/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clinical and Molecular differences of hypertensive disorders during pregnancy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12900390/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Plastic EMP1+ to LGR5+ Cell State Conversion as a Bypass to KRASG12D Pharmacologic Inhibition in Metastatic Colorectal Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877754/
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    Epigenetic and Transcriptional Programs Define Osteosarcoma Subtypes and Establish Targetable Vulnerabilities
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    pmc.ncbi.nlm.nih.gov/articles/PMC12877751/
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    New Insights Into the Role of Polo-Like Kinase 3 in Lung Tumorigenesis
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.70084
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    pmc.ncbi.nlm.nih.gov/articles/instance/12863058/bin/Supplemental_Material.pdf
  18. Jan 2026
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Broad Utility of Ultrasensitive Analysis of ctDNA Dynamics across Solid Tumors Treated with Immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12809116/
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In vitro protocol demonstrating five functional steps of trained immunity in mice: Implications on biomarker discovery and translational research
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    pmc.ncbi.nlm.nih.gov/articles/PMC12805498/
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    Unraveling SLAN+/− monocytes transcriptomics in lupus and extracellular vesicles effects
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    sciencedirect.com/science/article/pii/S0171298525002876
  22. Dec 2025
  23. www.biorxiv.org www.biorxiv.org
    Plasma cell identity escape drives resistance to anti-BCMA T-cell–redirecting therapy in multiple myeloma
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    biorxiv.org/content/10.64898/2025.12.08.692978v1
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tertiary lymphoid structure‐related RNA indicator as metastasis risk factor in nasopharyngeal carcinoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12705341/
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    Unveiling the prognostic and immunological role of IFI44 in glioma
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    tandfonline.com/doi/full/10.1080/07853890.2025.2593209
  26. Nov 2025
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting CDK12/13 Drives Mitotic Arrest to Overcome Resistance to KRASG12C Inhibitors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12638015/
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
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    pmc.ncbi.nlm.nih.gov/articles/PMC12635067/
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    Epigenetic profiling reveals key super-enhancer networks driving oncogenesis in HPV-positive HNSCC
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    SOCS1 Protects Acute Myeloid Leukemia against Allogeneic T Cell–Mediated Cytotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12050964/
  31. Oct 2025
  32. www.sciencedirect.com www.sciencedirect.com
    Identification of BET inhibitors (BETi) against solitary fibrous tumor (SFT) through high-throughput screening (HTS)
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    sciencedirect.com/science/article/pii/S1476558625001241
  33. www.science.org www.science.org
    Senataxin promotes recombination fidelity during antigen receptor gene diversification
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  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Intratumoral B cell and interferon signatures in newly diagnosed glioblastoma are associated with longer survival in patients treated with SurVaxM
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  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD27 agonist antibodies mediate clinical responses through intratumoral stimulation in B-cell malignancies: multicenter RiVa trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618221/
  36. Sep 2025
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A framework to mine laser microdissection-based omics data and uncover regulators of pancreatic cancer heterogeneity
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  38. aacrjournals.org aacrjournals.org
    Human papillomavirus integration induces oncogenic host gene fusions in oropharyngeal cancers
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    aacrjournals.org/cancerdiscovery/article/15/9/1927/764362/Human-Papillomavirus-Integration-Induces-Oncogenic
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    Differential Chromatin Accessibility, Gene Expression, and mRNA Splicing Between Developing Cochlear Inner and Outer Hair Cells
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    link.springer.com/article/10.1007/s10162-025-01005-z
  40. Aug 2025
  41. www.sciencedirect.com www.sciencedirect.com
    LINE-1 retrotransposons mediate cis-acting transcriptional control in human pluripotent stem cells and regulate early brain development
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  42. Jul 2025
  43. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    TAF1 is required for fetal but not adult hematopoiesis in mice
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  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
  47. www.cell.com www.cell.com
    TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice
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    cell.com/cell-stem-cell/fulltext/S1934-5909(25)00228-0
  48. Jun 2025
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Restoration of the Tumor Suppressor Function of Y220C-Mutant p53 by Rezatapopt, a Small-Molecule Reactivator
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  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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  51. May 2025
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Improvement in the function of self-activating chimeric antigen receptor by replacing the linker sequence
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  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic Plasticity Drives Carcinogenesis and Multi-Therapy Resistance in Multiple Myeloma
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  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Alternative mRNA splicing in anthracycline-induced cardiomyopathy – a COG-ALTE03N1 report
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  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Treatment Efficacy and Molecular Dynamics of Neoadjuvant Durvalumab and Olaparib in Resectable Urothelial Bladder Cancer: The NEODURVARIB Trial
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    pmc.ncbi.nlm.nih.gov/articles/PMC12010967/
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    MCRS1 sensitizes T cell–dependent immunotherapy by augmenting MHC-I expression in solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11572484/
  59. Apr 2025
  60. www.nature.com www.nature.com
    α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells
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    nature.com/articles/s41556-025-01658-1
  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD103+CD56+ ILCs Are Associated with an Altered CD8+ T-cell Profile within the Tumor Microenvironment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11962407/
  62. Mar 2025
  63. www.sciencedirect.com www.sciencedirect.com
    Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo
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  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation
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    Comparative analysis of AAV serotypes for transduction of olfactory sensory neurons
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  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acetalax and Bisacodyl for the Treatment of Triple-Negative Breast Cancer: A Combined Molecular and Preclinical Study
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    pmc.ncbi.nlm.nih.gov/articles/PMC11869203/
  67. Feb 2025
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    Multiomic QTL mapping reveals phenotypic complexity of GWAS loci and prioritizes putative causal variants
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    MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK
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    aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
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    Multiomics Profiling Distinguishes Sebaceous Carcinoma from Benign Sebaceous Neoplasms and Provides Insight into the Genetic Evolution of Sebaceous Carcinogenesis
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    A 5-hydroxymethylcytosine-based non-invasive model for early detection of colorectal carcinomas and advanced adenomas: the METHOD-2 study
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    aacrjournals.org/clincancerres/article/30/15/3337/746576/A-5-Hydroxymethylcytosine-Based-Noninvasive-Model
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    A Phase II Randomized Trial of Chemoradiation with or without Metformin in Locally Advanced Cervical Cancer
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    aacrjournals.org/clincancerres/article/28/24/5263/711455/A-Phase-II-Randomized-Trial-of-Chemoradiation-with
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    Repurposing statins and phenothiazines to treat chemoresistant neuroblastoma
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    biorxiv.org/content/10.1101/2025.01.28.635193v1
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    Using multiomic integration to improve blood biomarkers of major depressive disorder: a case-control study
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  77. Jan 2025
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma
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    Increased local DNA methylation disorder in AMLs with DNMT3A-destabilizing variants and its clinical implication
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  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    JAK inhibition decreases the autoimmune burden in Down syndrome
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  81. www.nature.com www.nature.com
    Hypoxia drives the formation of lung micropapillary adenocarcinoma-like structure through hypoxia-inducible factor-1α
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    nature.com/articles/s41598-024-80280-x
  82. Dec 2024
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single cell long read whole genome sequencing reveals somatic transposon activity in human brain
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  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
  85. Nov 2024
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  88. Oct 2024
  89. aacrjournals.org aacrjournals.org
    RNA sequencing and Immunohistochemistry Reveal ZFN7 as a Stronger Marker of Survival than Molecular Subtypes in G-CIMP–negative Glioblastoma
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    aacrjournals.org/clincancerres/article/27/2/645/83327/RNA-sequencing-and-Immunohistochemistry-Reveal
  90. aacrjournals.org aacrjournals.org
    Glioblastoma TCGA Mesenchymal and IGS 23 Tumors are Identifiable by IHC and have an Immune-phenotype Indicating a Potential Benefit from Immunotherapy
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    aacrjournals.org/clincancerres/article/26/24/6600/82892/Glioblastoma-TCGA-Mesenchymal-and-IGS-23-Tumors
  91. Sep 2024
  92. www.biorxiv.org www.biorxiv.org
    Metastatic tumor cells in bone marrow differ from paired neuroblastoma tumor and contain subsets with therapy-resistant characteristics
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    biorxiv.org/content/10.1101/2024.09.13.612231v1
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    A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies
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    biorxiv.org/content/10.1101/2024.09.12.612675v1
  94. Aug 2024
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator
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    ncbi.nlm.nih.gov/pmc/articles/PMC11310746/
  96. Jul 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11285331/
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multicellular, IVT-derived, unmodified human transcriptome for nanopore-direct RNA analysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11221353/
  100. May 2024
  101. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  102. Mar 2024
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-2-HG Inhibits IDH1mut Glioma Growth via FTO Inhibition and Resultant m6A Hypermethylation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10959073/
  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screen
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