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www.nature.com www.nature.com

PI3Kδ is selectively inhibited by roginolisib by stabilizing the C-terminal helix kα12

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1. scibot 15 Oct 2026
  
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  DOI: 10.1038/s41467-026-77424-0
  
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nature.com/articles/s41467-026-77424-0
Sep 2026
54.241.53.176 54.241.53.176

ccr-26-0805-html.html

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1. scibot 03 Sep 2026
  
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  DOI: 10.1158/1078-0432.ccr-26-0805
  
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54.241.53.176/7fc53958ca97b2e0c2d5412b179bc34b6a39df91/ccr-26-0805-html.html
Jul 2026
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B7-H3/CD276-specific nanobody T3CL11 enables tumor imaging in murine osteosarcoma and colorectal cancer models

1
1. scibot 30 Jul 2026
  
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  DOI: 10.1016/j.celrep.2026.117758
  
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sciencedirect.com/science/article/pii/S2211124726008363
Jun 2026
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Trio analysis in dystonia identifies de novo KLC1 variants in a kinesinopathy with distinct motor and neurodevelopmental features

1
1. scibot 30 Jun 2026
  
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  DOI: 10.1016/j.ebiom.2026.106358
  
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sciencedirect.com/science/article/pii/S2352396426002410
Sep 2025
elifesciences.org elifesciences.org

Structural evolution of nitrogenase over 3 billion years

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1. scibot 16 Sep 2025
  
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  DOI: 10.7554/eLife.105613
  
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elifesciences.org/articles/105613
Jul 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

M4205 (IDRX-42) Is a Highly Selective and Potent Inhibitor of Relevant Oncogenic Driver and Resistance Variants of KIT in Cancer

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1. scibot 04 Jul 2025
  
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  DOI: 10.1158/1535-7163.MCT-24-0699
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12214875/
Mar 2024
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ZP2 cleavage blocks polyspermy by modulating the architecture of the egg coat

2
1. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.013
  
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2. scibot 15 Mar 2024
  
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  DOI: 10.1016/j.cell.2024.02.013
  
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sciencedirect.com/science/article/pii/S009286742400179X
Feb 2024
elifesciences.org elifesciences.org

Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS607-family transposition

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1. scibot 08 Feb 2024
  
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  DOI: 10.7554/eLife.39611
  
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elifesciences.org/articles/39611
Nov 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STX-478, a Mutant-Selective, Allosteric PI3Kα Inhibitor Spares Metabolic Dysfunction and Improves Therapeutic Response in PI3Kα-Mutant Xenografts

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1. scibot 03 Nov 2023
  
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  DOI: 10.1158/2159-8290.CD-23-0396
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10618743/
Nov 2022
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IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling

1
1. scibot 05 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111489
  
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sciencedirect.com/science/article/pii/S2211124722013390
Mar 2022
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Structures of SAS-6 coiled coil hold implications for the polarity of the centriolar cartwheel

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1. scibot 04 Mar 2022
  
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  DOI: 10.1016/j.str.2022.02.005
  
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sciencedirect.com/science/article/pii/S0969212622000417
Jul 2021
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Site-Selective Antibody Functionalization via Orthogonally Reactive Arginine and Lysine Residues

1
1. scibot 29 Jul 2021
  
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  DOI: 10.1016/j.chembiol.2019.05.010
  
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sciencedirect.com/science/article/pii/S2451945619301795
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Cross-Reactive Donor-Specific CD8+ Tregs Efficiently Prevent Transplant Rejection

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1. scibot 28 Jul 2021
  
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  DOI: 10.1016/j.celrep.2019.11.106
  
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sciencedirect.com/science/article/pii/S2211124719316298
Apr 2021
www.cell.com www.cell.com

SARS-CoV-2 evolution in an immunocompromised host reveals shared neutralization escape mechanisms

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1. scibot 08 Apr 2021
  
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  DOI: 10.1016/j.cell.2021.03.027
  
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cell.com/cell/fulltext/S0092-8674(21)00355-X
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

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1. scibot 09 Mar 2021
  
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  DOI: 10.7554/eLife.65339
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7924943/
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cannabidiol interactions with voltage-gated sodium channels

1
1. scibot 12 Nov 2020
  
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  DOI: 10.7554/eLife.58593
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7641581/
Sep 2020
elifesciences.org elifesciences.org

Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas

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1. scibot 12 Sep 2020
  
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  RRID:SCR_015653
  
  DOI: 10.7554/eLife.50004
  
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elifesciences.org/articles/50004
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Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor IL-17RC to Drive IL-17RA-Independent Signaling

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1. scibot 08 Sep 2020
  
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  RRID:SCR_015653
  
  DOI: 10.1016/j.immuni.2020.02.004
  
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sciencedirect.com/science/article/pii/S1074761320300753
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Insights into herpesvirus assembly from the structure of the pUL7:pUL51 complex

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1. scibot 07 Sep 2020
  
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  DOI: 10.7554/eLife.53789
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7289601/
Jan 2020
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Design on a Rational Basis of High-Affinity Peptides Inhibiting the Histone Chaperone ASF1

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.chembiol.2019.09.002
  
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sciencedirect.com/science/article/pii/S2451945619302764
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Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins

1
1. scibot 13 Jan 2020
  
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  DOI: 10.1016/j.cell.2019.08.038
  
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sciencedirect.com/science/article/pii/S0092867419309572
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint

1
1. scibot 13 Jan 2020
  
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  DOI: 10.7554/eLife.44353
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
www.cell.com www.cell.com

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies

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1. scibot 13 Jan 2020
  
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  RRID:SCR_015653
  
  DOI: 10.1016/j.cell.2019.05.025
  
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cell.com/cell/fulltext/S0092-8674(19)30553-7
Nov 2018
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6188088/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Human LINE-1 retrotransposition requires a metastable coiled coil and a positively charged N-terminus in L1ORF1p

1
1. scibot 05 Nov 2018
  
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  BUSTER
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5940361/
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In Crystallo Selection to Establish New RNA Crystal Contacts

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1. scibot 05 Nov 2018
  
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sciencedirect.com/science/article/pii/S0969212618301692
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Robo1 Forms a Compact Dimer-of-Dimers Assembly

1
1. scibot 05 Nov 2018
  
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  Buster
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5807052/
elifesciences.org elifesciences.org

Untitled document

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1. scibot 05 Nov 2018
  
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  SCR_015653
  
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elifesciences.org/articles/31529
europepmc.org europepmc.org

A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

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1. scibot 05 Nov 2018
  
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europepmc.org/articles/PMC5655547/
Nov 2017
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Structural Basis for Apelin Control of the Human Apelin Receptor

1
1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S0969212617301260