Hypothesis

40 Matching Annotations

Jan 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226001896-main-html.html

1
1. scibot 29 Jan 2026
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.isci.2026.114814
  
  Resource: None
  
  Curator: @areedewitt04
  
  SciCrunch record: RRID:SCR_016654
  
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  RRIDCUR:Unresolved RRID:SCR_016654
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54.241.53.176/3822e41eb5bd42b05d252c55463d50c0cecf8e0e/1-s2.0-S2589004226001896-main-html.html
Sep 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress

1
1. scibot 06 Sep 2025
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1126/sciadv.ady0240
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12383277/
www.science.org www.science.org

Putative PINK1/Parkin activators lower the threshold for mitophagy by sensitizing cells to mitochondrial stress

1
1. scibot 03 Sep 2025
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1126/sciadv.ady0240
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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science.org/doi/10.1126/sciadv.ady0240
Aug 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

TBK1 Targeting is Identified as a Therapeutic Strategy to Enhance CAR T-Cell Efficacy Using Patient-Derived Organotypic Tumor Spheroids

1
1. scibot 05 Aug 2025
  
  in Public
  
  SCR_016654
  
  DOI: 10.1158/2326-6066.CIR-23-1011
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @sonofthor
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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pmc.ncbi.nlm.nih.gov/articles/PMC11790382/
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The mitophagy receptors BNIP3 and NIX mediate tight attachment and expansion of the isolation membrane to mitochondria

1
1. scibot 19 May 2025
  
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  RRID:SCR_016654
  
  DOI: 10.1083/jcb.202408166
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12071194/
www.sciencedirect.com www.sciencedirect.com

Regional differences in progenitor metabolism shape brain growth during development

1
1. scibot 16 May 2025
  
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  RRID:SCR_016654
  
  DOI: 10.1016/j.cell.2025.04.003
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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sciencedirect.com/science/article/pii/S0092867425004052
Apr 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer

1
1. scibot 04 Apr 2025
  
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  RRID:SCR_016654
  
  DOI: 10.1158/1535-7163.MCT-24-0785
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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pmc.ncbi.nlm.nih.gov/articles/PMC11962390/
www.sciencedirect.com www.sciencedirect.com

Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

1
1. scibot 01 Apr 2025
  
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  RRID:SCR_016654
  
  DOI: 10.1016/j.chom.2025.03.008
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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sciencedirect.com/science/article/pii/S1931312825000915
Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids

1
1. scibot 12 Feb 2025
  
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  RRID:SCR_016654
  
  DOI: 10.7554/eLife.92180
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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pmc.ncbi.nlm.nih.gov/articles/PMC11810108/
Oct 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Moesin contributes to heat shock gene response through direct binding to the Med15 subunit of the Mediator complex in the nucleus

1
1. scibot 04 Oct 2024
  
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  RRID:SCR_016654
  
  DOI: 10.1098/rsob.240110
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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ncbi.nlm.nih.gov/pmc/articles/PMC11444770/
aacrjournals.org aacrjournals.org

A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier

1
1. scibot 02 Oct 2024
  
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  RRID:SCR_016654
  
  DOI: 10.1158/0008-5472.CAN-19-3911
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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aacrjournals.org/cancerres/article/81/3/619/648134/A-High-Content-Screen-Identifies-Drugs-That
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Drug Discovery Pipeline for MAPK/ERK Pathway Inhibitors in Caenorhabditis elegans

1
1. scibot 25 Sep 2024
  
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  RRID:SCR_016654
  
  DOI: 10.1158/2767-9764.CRC-24-0221
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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ncbi.nlm.nih.gov/pmc/articles/PMC11409438/
Aug 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability

1
1. scibot 21 Aug 2024
  
  in Public
  
  SCR_016654
  
  DOI: 10.1016/j.molcel.2024.07.018
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC11366124/
Apr 2024
www.sciencedirect.com www.sciencedirect.com

GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the type-1 cannabinoid receptor and the consequences on G protein signalling

1
1. scibot 12 Apr 2024
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.bcp.2024.116190
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

sciencedirect.com/science/article/pii/S0006295224001734
www.sciencedirect.com www.sciencedirect.com

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

1
1. scibot 09 Apr 2024
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.cell.2024.03.015
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

sciencedirect.com/science/article/pii/S0092867424003064
Mar 2024
www.cell.com www.cell.com

LncRNA Litchi is a Regulator for Harmonizing Maturity and Resilient Functionality in Spinal Motor Neurons

2
1. scibot 07 Mar 2024
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.isci.2024.109207
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
  What is this?
  
  RRID:SCR_016654
2. scibot 06 Mar 2024
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.isci.2024.109207
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

cell.com/iscience/fulltext/S2589-0042(24)00428-0
Oct 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PROTAC-mediated selective degradation of cytosolic soluble epoxide hydrolase enhances ER-stress reduction

1
1. scibot 21 Oct 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1021/acschembio.3c00017
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

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ncbi.nlm.nih.gov/pmc/articles/PMC10586715/
52.53.155.43 52.53.155.43

Regional Differences in Progenitor Consumption Dynamics Shape Brain Growth during Development

1
1. scibot 20 Oct 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1101/2023.08.21.553891
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

52.53.155.43/5bdf2fa224e97e51381904afe971b5853c9aac1a/2023.08.21.553891.full-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex

1
1. scibot 06 Oct 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.celrep.2023.112838
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10529098/
Jul 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer

1
1. scibot 15 Jul 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.3390/ijms241310870
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC10342141/
www.pnas.org www.pnas.org

The molecular mechanism of CD81 antibody inhibition of metastasis

1
1. scibot 07 Jul 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1073/pnas.2305042120
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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scibot

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pnas.org/doi/abs/10.1073/pnas.2305042120
Apr 2023
www.sciencedirect.com www.sciencedirect.com

Gamma secretase activity modulates BMP-7-induced dendritic growth in primary rat sympathetic neurons

1
1. scibot 08 Apr 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.autneu.2023.103085
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

sciencedirect.com/science/article/pii/S1566070223000140
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

GSK-3 inhibitor elraglusib enhances tumor-infiltrating immune cell activation in tumor biopsies and synergizes with anti-PD-L1 in a murine model of colorectal cancer

1
1. scibot 10 Mar 2023
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1101/2023.02.07.527499
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC9934544/
Mar 2022
www.sciencedirect.com www.sciencedirect.com

BMI-1 regulates DNA end resection and homologous recombination repair

1
1. scibot 23 Mar 2022
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.celrep.2022.110536
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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scibot

URL

sciencedirect.com/science/article/pii/S2211124722002777
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice

1
1. scibot 12 Nov 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.xcrm.2021.100434
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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scibot

URL

sciencedirect.com/science/article/pii/S2666379121002962
Oct 2021
www.mdpi.com www.mdpi.com

Active Targeted Nanoemulsions for Repurposing of Tegaserod in Alzheimer’s Disease Treatment

1
1. scibot 18 Oct 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.3390/pharmaceutics13101626
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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mdpi.com/1999-4923/13/10/1626
Sep 2021
www.sciencedirect.com www.sciencedirect.com

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

1
1. scibot 11 Sep 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.molcel.2021.08.016
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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scibot

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sciencedirect.com/science/article/pii/S1097276521006833
Jul 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 29 Jul 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1111/bph.14852
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14852
journals.plos.org journals.plos.org

The alpha-1 subunit of the Na+,K+-ATPase (ATP1A1) is required for macropinocytic entry of respiratory syncytial virus (RSV) in human respiratory epithelial cells

1
1. scibot 29 Jul 2021
  
  in Public
  
  MetaXpress
  
  DOI: 10.1371/journal.ppat.1007963
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_016654
  
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  RRIDCUR:Missing RRID:SCR_016654
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RRID:SCR_016654

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scibot

URL

journals.plos.org/plospathogens/article
www.sciencedirect.com www.sciencedirect.com

Combined morphological and proteome profiling reveals target-independent impairment of cholesterol homeostasis

1
1. scibot 02 Jul 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.chembiol.2021.06.003
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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sciencedirect.com/science/article/pii/S2451945621003020
May 2021
www.sciencedirect.com www.sciencedirect.com

HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis

1
1. scibot 07 May 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.molcel.2020.04.031
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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sciencedirect.com/science/article/pii/S1097276520302732
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin

1
1. scibot 28 Apr 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.chembiol.2021.02.017
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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sciencedirect.com/science/article/pii/S2451945621001021
www.sciencedirect.com www.sciencedirect.com

Functional interrogation of DNA damage response variants with base editing screens

1
1. scibot 12 Apr 2021
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.cell.2021.01.041
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654
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sciencedirect.com/science/article/pii/S0092867421000842
Sep 2020
www.sciencedirect.com www.sciencedirect.com

Plasmodium vivax Liver and Blood Stages Recruit the Druggable Host Membrane Channel Aquaporin-3

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1016/j.chembiol.2020.03.009
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:SCR_016654
  
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  RRIDCUR:Validated RRID:SCR_016654
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RRIDCUR:Validated

RRID:SCR_016654

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scibot

URL

sciencedirect.com/science/article/pii/S2451945620300830
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 17 Sep 2020
  
  in Public
  
  RRID:SCR_016654
  
  DOI: 10.1111/bph.14964
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654 RRIDCUR:Validated
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RRIDCUR:Validated

RRID:SCR_016654

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scibot

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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14964
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Intravenous antagomiR‐494 lessens brain‐infiltrating neutrophils by increasing HDAC2‐mediated repression of multiple MMPs in experimental stroke

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1. scibot 13 Sep 2020
  
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  RRID:SCR_016654
  
  DOI: 10.1096/fj.201903127R
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @Naa003
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201903127R
www.nature.com www.nature.com

Effects of cytokines on nuclear factor-kappa B, cell viability, and synaptic connectivity in a human neuronal cell line

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1. scibot 09 Sep 2020
  
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  RRID:SCR_016654
  
  DOI: 10.1038/s41380-020-0647-2
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @evieth
  
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nature.com/articles/s41380-020-0647-2
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Resolving Cell Cycle Speed in One Snapshot with a Live-Cell Fluorescent Reporter

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1. scibot 03 Sep 2020
  
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  RRID:SCR_016654
  
  DOI: 10.1016/j.celrep.2020.107804
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:SCR_016654
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ncbi.nlm.nih.gov/pmc/articles/PMC7418154/
Jan 2020
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Untitled document

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1. scibot 13 Jan 2020
  
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  RRID:SCR_016654
  
  DOI: 10.1111/bph.14684
  
  Resource: MetaXpress (RRID:SCR_016654)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_016654
  
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  RRID:SCR_016654 RRIDCUR:Validated
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14684