54 Matching Annotations
  1. Nov 2024
  2. www.biorxiv.org www.biorxiv.org
    Inhibition of Parkinson’s Disease-related LRRK2 by type-I and type-II kinase inhibitors: activity and structures
    1
    1. scibot 26 Nov 2024
      RRID:SCR_016732

      DOI: 10.1101/2023.09.07.556689

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    biorxiv.org/content/10.1101/2023.09.07.556689v1
  3. Sep 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2
    1
    1. scibot 25 Sep 2024
      RRID:SCR_016731

      DOI: 10.7554/eLife.59991

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    ncbi.nlm.nih.gov/pmc/articles/PMC7434445/
  5. elifesciences.org elifesciences.org
    Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1
    1
    1. scibot 25 Sep 2024
      RRID:SCR_016731

      DOI: 10.7554/eLife.59555

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    elifesciences.org/articles/59555
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gating and selectivity mechanisms for the lysosomal K+ channel TMEM175
    1
    1. scibot 25 Sep 2024
      RRID:SCR_016731

      DOI: 10.7554/eLife.53430

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    ncbi.nlm.nih.gov/pmc/articles/PMC7141809/
  7. Jun 2024
  8. www.sciencedirect.com www.sciencedirect.com
    A designed ankyrin-repeat protein that targets Parkinson’s disease-associated LRRK2
    1
    1. scibot 21 Jun 2024
      RRID:SCR_016732

      DOI: 10.1016/j.jbc.2024.107469

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    sciencedirect.com/science/article/pii/S0021925824019707
  9. www.cell.com www.cell.com
    POT1 recruits and regulates CST-Polα/primase at human telomeres
    1
    1. scibot 05 Jun 2024
      RRID:SCR_016732

      DOI: 10.1016/j.cell.2024.05.002

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    cell.com/cell/fulltext/S0092-8674(24)00493-8
  10. Apr 2024
  11. www.cell.com www.cell.com
    Structural basis of ligand specificity and channel activation in an insect gustatory receptor
    1
    1. scibot 04 Apr 2024
      RRID:SCR_016732

      DOI: 10.1016/j.celrep.2024.114035

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    cell.com/cell-reports/fulltext/S2211-1247(24)00363-2
  12. Nov 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa
    1
    1. scibot 03 Nov 2023
      RRID:SCR_016732

      DOI: 10.1016/j.cell.2023.10.002

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    sciencedirect.com/science/article/pii/S009286742301084X
  14. Aug 2023
  15. 52.53.155.43 52.53.155.43
    EMBO Reports - 2023 - Jiang-html.html
    1
    1. scibot 16 Aug 2023
      RRID:SCR_016732

      DOI: 10.15252/embr.202356864

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    52.53.155.43/72eed5338814ac6922d23d3395f365b4e68799b2/EMBO Reports - 2023 - Jiang-html.html
  16. Jul 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sterol derivative binding to the orthosteric site causes conformational changes in an invertebrate Cys-loop receptor
    1
    1. scibot 14 Jul 2023
      RRID:SCR_016732

      DOI: 10.7554/eLife.86029

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    ncbi.nlm.nih.gov/pmc/articles/PMC10338036/
  18. Jun 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Type IV-A CRISPR-Csf complex: Assembly, dsDNA targeting, and CasDinG recruitment
    1
    1. scibot 21 Jun 2023
      RRID:SCR_016732

      DOI: 10.1016/j.molcel.2023.05.036

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    sciencedirect.com/science/article/pii/S1097276523004203
  20. Mar 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structures of mitochondrial respiratory complex I from Drosophila melanogaster
    1
    1. scibot 05 Mar 2023
      RRID:SCR_016732

      DOI: 10.7554/eLife.84424

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    ncbi.nlm.nih.gov/pmc/articles/PMC9977279/
  22. Jan 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
    1
    1. scibot 02 Jan 2023
      RRID:SCR_016732

      DOI: 10.1016/j.celrep.2022.111902

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    sciencedirect.com/science/article/pii/S2211124722018010
  24. Dec 2022
  25. www.nature.com www.nature.com
    Structural basis for Parkinson’s disease-linked LRRK2’s binding to microtubules
    1
    1. scibot 13 Dec 2022
      RRID:SCR_016732

      DOI: 10.1038/s41594-022-00863-y

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    nature.com/articles/s41594-022-00863-y
  26. Mar 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Structural basis for catalyzed assembly of the Sonic hedgehog–Patched1 signaling complex
    1
    1. scibot 02 Mar 2022
      RRID:SCR_016732

      DOI: 10.1016/j.devcel.2022.02.008

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    sciencedirect.com/science/article/pii/S1534580722000740
  28. Nov 2021
  29. www.sciencedirect.com www.sciencedirect.com
    Structure and assembly pattern of a freshwater short-tailed cyanophage Pam1
    1
    1. scibot 02 Nov 2021
      RRID:SCR_016732

      DOI: 10.1016/j.str.2021.10.004

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    sciencedirect.com/science/article/pii/S0969212621003725
  30. Oct 2021
  31. www.cell.com www.cell.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
    1
    1. scibot 27 Oct 2021
      RRID:SCR_016732

      DOI: 10.1016/j.celrep.2021.109877

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    cell.com/cell-reports/fulltext/S2211-1247(21)01347-4
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM120A contains a specific coenzyme A-binding site and might not mediate poking- or stretch-induced channel activities in cells
    1
    1. scibot 02 Oct 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.71474

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    ncbi.nlm.nih.gov/pmc/articles/PMC8480983/
  33. Sep 2021
  34. elifesciences.org elifesciences.org
    Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome
    1
    1. scibot 30 Sep 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.71420

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    elifesciences.org/articles/71420
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of human mTOR complexes by DEPTOR
    1
    1. scibot 18 Sep 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.70871

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    ncbi.nlm.nih.gov/pmc/articles/PMC8439649/
  36. Aug 2021
  37. elifesciences.org elifesciences.org
    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
    1
    1. scibot 25 Aug 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.68110

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    elifesciences.org/articles/68110
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structure of Escherichia coli respiratory complex I reconstituted into lipid nanodiscs reveals an uncoupled conformation
    1
    1. scibot 17 Aug 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.68710

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    ncbi.nlm.nih.gov/pmc/articles/PMC8357420/
  39. Jul 2021
  40. elifesciences.org elifesciences.org
    Mechanism of pharmacochaperoning in a mammalian KATP channel revealed by cryo-EM
    1
    1. scibot 29 Jul 2021
      CTFFIND

      DOI: 10.7554/eLife.46417

      Resource: CTFFIND (RRID:SCR_016732)

      Curator: @Naa003

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      RRIDCUR:Missing RRID:SCR_016732
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    elifesciences.org/articles/46417
  41. www.sciencedirect.com www.sciencedirect.com
    Structure of the Mechanosensitive Channel MscS Embedded in the Membrane Bilayer
    1
    1. scibot 29 Jul 2021
      CTFFind4

      DOI: 10.1016/j.jmb.2019.07.006

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    sciencedirect.com/science/article/pii/S0022283619304279
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core
    1
    1. scibot 27 Jul 2021
      CTFFIND4

      DOI: 10.7554/eLife.37688

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    ncbi.nlm.nih.gov/pmc/articles/PMC6237438/
  43. May 2021
  44. www.sciencedirect.com www.sciencedirect.com
    The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain
    1
    1. scibot 09 May 2021
      RRID:SCR_016732

      DOI: 10.1016/j.str.2020.06.008

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    sciencedirect.com/science/article/pii/S0969212620302112
  45. www.sciencedirect.com www.sciencedirect.com
    Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis
    1
    1. scibot 07 May 2021
      RRID:SCR_016732

      DOI: 10.1016/j.molcel.2020.08.010

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    sciencedirect.com/science/article/pii/S1097276520305530
  46. Apr 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
    1
    1. scibot 28 Apr 2021
      RRID:SCR_016732

      DOI: 10.1016/j.str.2021.04.003

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    sciencedirect.com/science/article/pii/S0969212621001192
  48. elifesciences.org elifesciences.org
    Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor
    1
    1. scibot 06 Apr 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.66097

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    elifesciences.org/articles/66097
  49. Mar 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A pentameric protein ring with novel architecture is required for herpesviral packaging
    1
    1. scibot 02 Mar 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.62261

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    ncbi.nlm.nih.gov/pmc/articles/PMC7889075/
  51. www.sciencedirect.com www.sciencedirect.com
    Structural basis for self-cleavage prevention by tag:anti-tag pairing complementarity in type VI Cas13 CRISPR systems
    1
    1. scibot 01 Mar 2021
      RRID:SCR_016732

      DOI: 10.1016/j.molcel.2020.12.033

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    sciencedirect.com/science/article/pii/S1097276520309540
  52. Feb 2021
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
    1
    1. scibot 26 Feb 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.56664

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    ncbi.nlm.nih.gov/pmc/articles/PMC7447434/
  54. Jan 2021
  55. elifesciences.org elifesciences.org
    Atomic structures of respiratory complex III 2, complex IV, and supercomplex III 2-IV from vascular plants
    1
    1. scibot 23 Jan 2021
      RRID:SCR_016732

      DOI: 10.7554/eLife.62047

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    elifesciences.org/articles/62047
  56. Dec 2020
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large domain movements through the lipid bilayer mediate substrate release and inhibition of glutamate transporters
    1
    1. scibot 07 Dec 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.58417

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    ncbi.nlm.nih.gov/pmc/articles/PMC7682989/
  58. Nov 2020
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of ClpXP recognition and unfolding of ssrA-tagged substrates
    1
    1. scibot 18 Nov 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.61496

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    ncbi.nlm.nih.gov/pmc/articles/PMC7652416/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of αE-catenin–F-actin catch bond behavior
    1
    1. scibot 13 Nov 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.60878

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    ncbi.nlm.nih.gov/pmc/articles/PMC7588230/
  61. Oct 2020
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular mechanism for direct actin force-sensing by α-catenin
    1
    1. scibot 31 Oct 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.62514

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    ncbi.nlm.nih.gov/pmc/articles/PMC7588232/
  63. Sep 2020
  64. elifesciences.org elifesciences.org
    Cryo-EM structures of S-OPA1 reveal its interactions with membrane and changes upon nucleotide binding
    1
    1. scibot 25 Sep 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.50294

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    elifesciences.org/articles/50294
  65. elifesciences.org elifesciences.org
    Molecular principles of assembly, activation, and inhibition in epithelial sodium channel
    1
    1. scibot 17 Sep 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.59038

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    elifesciences.org/articles/59038
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical and structural investigation of the paroxetine-human serotonin transporter complex
    1
    1. scibot 16 Sep 2020
      RRID:SCR_016732

      DOI: 10.7554/eLife.56427

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    ncbi.nlm.nih.gov/pmc/articles/PMC7470834/
  67. www.sciencedirect.com www.sciencedirect.com
    Cryo-EM Reveals Integrin-Mediated TGF-β Activation without Release from Latent TGF-β
    1
    1. scibot 13 Sep 2020
      RRID:SCR_016732

      DOI: 10.1016/j.cell.2019.12.030

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  68. elifesciences.org elifesciences.org
    Structure and activation mechanism of the BBSome membrane protein trafficking complex
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Limited dishevelled/Axin oligomerization determines efficiency of Wnt/β-catenin signal transduction
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  70. elifesciences.org elifesciences.org
    Moyamoya disease factor RNF213 is a giant E3 ligase with a dynein-like core and a distinct ubiquitin-transfer mechanism
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      DOI: 10.7554/eLife.56185

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  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural basis of substrate recognition by a polypeptide processing and secretion transporter
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structures of the ATP-fueled ClpXP proteolytic machine bound to protein substrate
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atomic structure of a mitochondrial complex I intermediate from vascular plants
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  75. Jan 2020
  76. elifesciences.org elifesciences.org
    Regulation of Eag1 gating by its intracellular domains
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      DOI: 10.7554/eLife.49188

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  77. www.sciencedirect.com www.sciencedirect.com
    Multisystem Proteinopathy Mutations in VCP/p97 Increase NPLOC4·UFD1L Binding and Substrate Processing
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  78. www.cell.com www.cell.com
    Capsid Structure of a Freshwater Cyanophage Siphoviridae Mic1
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    Near-Complete Structure and Model of Tel1ATM from Chaetomium thermophilum Reveals a Robust Autoinhibited ATP State
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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