33 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Dual targeting of topoisomerase I and DNA G-quadruplexes enhances senescence and chemosensitivity in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13100145/
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nutrient Availability Dictates Cancer Metabolism–Based Therapeutic Responses to Nononcology Drugs
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    pmc.ncbi.nlm.nih.gov/articles/PMC13055633/
  5. Jan 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Sevabertinib, a Reversible HER2 Inhibitor with Activity in Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12793832/
  7. Nov 2025
  8. www.nature.com www.nature.com
    A moonlighting function of tumoral interleukin-1β precursor promotes metastasis via RACK1-mediated actin remodeling
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    nature.com/articles/s41467-025-65220-1
  9. Sep 2025
  10. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Colchicine Modulates the Actin Cytoskeleton by Direct Binding to the Monomer and Facilitating Polymerization
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202501907R
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Repurposing rupatadine as topical treatment against methicillin-resistant Staphylococcus aureus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457276/
  12. Jul 2025
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    Gmelinol ameliorates type 2 diabetes and multi-organ complications in streptozotocin-nicotinamide-induced diabetic rats
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    link.springer.com/article/10.1007/s00210-025-04476-2
  14. Jun 2025
  15. www.sciencedirect.com www.sciencedirect.com
    GRK-biased adrenergic agonists for the treatment of type 2 diabetes and obesity
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    sciencedirect.com/science/article/pii/S0092867425006300
  16. Apr 2025
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development
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    pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
  18. Jan 2025
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    Structural and functional analysis of the Nipah virus polymerase complex
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    sciencedirect.com/science/article/pii/S009286742401434X
  20. Nov 2024
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    sciencedirect.com/science/article/pii/S1934590924003692
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    In silico drug repurposing using molecular docking and dynamics to target the protein interaction between the SARS-CoV-2 S-glycoprotein and the ACE2 receptor
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    pmc.ncbi.nlm.nih.gov/articles/PMC11519612/
  23. Oct 2024
  24. elifesciences.org elifesciences.org
    Inhibitors of the small membrane (M) protein viroporin prevent Zika virus infection
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    elifesciences.org/articles/68404
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic Signatures and Therapeutic Targets in Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443238/
  26. Aug 2024
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    Viral DNA polymerase structures reveal mechanisms of antiviral drug resistance
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    sciencedirect.com/science/article/pii/S0092867424008420
  28. Jul 2024
  29. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site
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    onlinelibrary.wiley.com/doi/10.1111/jnc.16179
  30. Jun 2024
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction
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    onlinelibrary.wiley.com/doi/10.1002/advs.202307695
  32. Dec 2023
  33. f1000research.com f1000research.com
    <i>In silico</i> drug repurposing using molecular docking and dynamics to target the protein interaction between the SARS-CoV-2 S-glycoprotein and the ACE2 receptor
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    f1000research.com/articles/12-1452
  34. Oct 2023
  35. www.sciencedirect.com www.sciencedirect.com
    Breast Cancer Cells are Sensitized by Piperine to Radiotherapy through Estrogen Receptor-α mediated modulation of a Key NHEJ repair protein- DNA-PK
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    sciencedirect.com/science/article/pii/S0944711323004865
  36. Jul 2023
  37. link.springer.com link.springer.com
    Virtual Screening, Molecular Docking, and Dynamic Simulations Revealed TGF-β1 Potential Inhibitors to Curtail Cervical Cancer Progression
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    link.springer.com/article/10.1007/s12010-023-04608-5
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation
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    sciencedirect.com/science/article/pii/S2451945623001502
  40. Aug 2022
  41. f1000research.com f1000research.com
    F1000Research Article: New findings on ligand series used as SARS-CoV-2 virus inhibitors within the frameworks of molecular docking, molecular quantum similarity and chemical reactivity indices.
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    f1000research.com/articles/11-914
  42. Jul 2022
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15913
  44. Jun 2022
  45. pubs.acs.org pubs.acs.org
    Diterpenoid Constituents of Psiadia punctulata and Evaluation of Their Antimicrobial Activity
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    pubs.acs.org/doi/full/10.1021/acs.jnatprod.1c01093
  46. www.nature.com www.nature.com
    Targeting LIPA independent of its lipase activity is a therapeutic strategy in solid tumors via induction of endoplasmic reticulum stress
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    nature.com/articles/s43018-022-00389-8
  47. Apr 2021
  48. www.sciencedirect.com www.sciencedirect.com
    Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor
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    sciencedirect.com/science/article/pii/S0969212621001179
  49. Mar 2021
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homology Model of a Catalytically Competent Bifunctional Rel Protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7983052/
  51. Dec 2020
  52. elifesciences.org elifesciences.org
    Rationally derived inhibitors of hepatitis C virus (HCV) p7 channel activity reveal prospect for bimodal antiviral therapy
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    elifesciences.org/articles/52555
  53. Sep 2020
  54. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14970
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15076
  56. Jan 2020
  57. www.sciencedirect.com www.sciencedirect.com
    Aryl Hydrocarbon Receptor Modulation by Tuberculosis Drugs Impairs Host Defense and Treatment Outcomes
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    sciencedirect.com/science/article/pii/S1931312819306341
  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14774
  59. www.sciencedirect.com www.sciencedirect.com
    Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site
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    sciencedirect.com/science/article/pii/S2211124719302864